Best Large Grants for Nonprofit Organizations in Maine

About Legacy Foundation

Legacy Foundation is the community foundation for Lake County, Indiana. We connect people, knowledge, and funding to build an equitable, accessible, and inclusive Lake County, now and for generations to come.

Legacy Foundation is supported by a broad base of individuals, families, and businesses connected by the desire to improve Lake County, Indiana. With a growing portfolio of over 300 funds and approximately $80 million in assets, Legacy Foundation is a trusted source for philanthropic giving in the region.

For over 30 years, Legacy Foundation has been empowering people, providing strategic leadership, and impactful philanthropic support to create an equitable Lake County where all people thrive.

Mission Statement

Transforming Lake County by providing strategic leadership and impactful philanthropic support to ensure equitable opportunity for all communities that we serve.

Vision Statement

Create an equitable Lake County where all people thrive.

Cenifax Scholarship

Use the chart below to see which scholarships are the best fit for you! You must complete the Legacy Universal Application to apply.

Scholarship eligibility requires students to attend an accredited 2 or 4 year public or private institution of higher learning. All scholarships are for full-time students, unless otherwise noted. Renewable awards are for 4 years of undergraduate study and cannot be used for post graduate coursework; all awards are paid directly to the school or may be used for book reimbursement.

The Autism Centers of Excellence R01 aims to advance research in autism through collaborative networks, enhancing the past 23 years of progress. This initiative encourages innovative methods and technologies, inviting experts to consider applying for future funding opportunities. Although applications are not currently solicited, potential applicants are urged to form meaningful collaborations. This funding opportunity reflects a commitment to improving research in autism, leveraging diverse scientific expertise to address critical challenges in the field.

The Autism Centers of Excellence (ACE) initiative, spearheaded by the Eunice Kennedy Shriver National Institute for Child Health and Human Development along with several other prominent institutes, aims to encourage innovative research projects. While applications are not currently open, potential applicants are urged to prepare collaborative proposals that leverage cutting-edge technologies. This funding opportunity, utilizing the P50 Research Program Projects and Centers activity code, seeks to build upon over two decades of research advancements.

The FY26 Alzheimer’s Research Program's Transforming Diagnosis Award (TrDA) promotes innovative research aimed at overcoming significant barriers to accurate diagnosis and monitoring of Alzheimer's disease. This award encourages community collaboration and requires preliminary data. It supports studies leveraging existing cohorts, especially those including individuals aged 65 and younger. The TrDA also offers a partnership option for multiple principal investigators, fostering collaborative research efforts while ensuring at least one independent investigator meets eligibility criteria.

The DoW Alzheimer’s Transforming Research Award supports innovative research aimed at reducing the risk and preventing Alzheimer’s disease and related dementias. It emphasizes projects that enhance understanding of risk factors and develop effective risk reduction strategies. Clinical research is permitted, but trials and animal studies are not. Collaboration and preliminary data are essential for proposal consideration, and an option for multiple principal investigators is available to foster partnerships.

The Ovarian Cancer Clinical Trial Academy (OCCTA) supports Early-Career Investigators (ECIs) in clinical trial research aimed at effective ovarian cancer treatments. It provides essential mentoring, networking, and skill development needed for executing clinical trials. The FY26 funding will specifically support translational research and early-phase trials, requiring preliminary data and a commitment of at least 25% effort from the ECI. Mentorship is vital, with a focus on experienced clinical trialists guiding ECIs.

The Believe in Reading Grant, offered by The Steve and Loree Potash Family Foundation, targets established literacy programs with a proven track record. The foundation aims to support initiatives that address literacy across various age groups, particularly in areas of high need. Grants can be up to $10,000, with a focus on projects that earmark funds specifically for literacy. Applications are reviewed bi-monthly, and first-time applicants are limited to $3,000.

The Max L. and Marilyn Harshman Scholarship, offered by the Ashland County Community Foundation, supports high school graduates who are in their senior year of college majoring in Social Work. Eligible applicants must have a minimum GPA of 3.0. This scholarship aims to assist students in pursuing their educational goals while contributing to the community through their chosen field.

The Small Business Transition Grant for New Entrepreneurs, funded by the NIH, aims to support early-career scientists as they transition into entrepreneurship. This program invites eligible small business concerns to apply for STTR Phase I and Fast-Track grant applications, which include funding for research and development, as well as essential entrepreneurial training and mentorship. It is designed for first-time Principal Investigators, emphasizing the importance of industry mentorship in project development.

The FY26 Arthritis Research Program Clinical Research Award supports innovative clinical research addressing factors and interventions for arthritis. This program encourages proposals focusing on Prevention and Early Diagnosis or Treatment and Mitigation of Disease Progression. Applicants can choose between two research levels, with the requirement of a community collaborator for Research Level 2. Projects should aim to provide actionable evidence to enhance patient care and outcomes, making significant contributions to the field of arthritis research.

Native Forward awards are allocated based on the financial aid information provided by the institution’s Financial Aid Office. Awards can vary, ranging from $100 to $30,000 per academic year.

Native Forward Scholars Fund members of federally and state-recognized Tribes as well as first and second-generation descendants. However, Native Forward Scholars Fund scholarship opportunities have different Tribal eligibility requirements and can be determined by submitting a Tribal Eligibility Certificate.

Grace Wall Barreda Memorial Scholarship

This opportunity is provided to honor the life and legacy of Grace Wall Barreda.

The purpose of the Grace Wall Barreda Scholarship program is to provide financial assistance to eligible American Indian and Alaska Native graduate students pursuing degrees full-time at an accredited institution in Public Health or Environmental Science/Studies.

This opportunity is a need-based award.

The SETAC North America Student Meeting Attendance Grant supports student participation in annual meetings, emphasizing inclusivity and excellence. This program provides waived registration and stipends for costs such as travel and dependent care. Eligible students can apply during abstract submission from March to May, with grants available for each degree program. The initiative encourages applicants from diverse backgrounds, particularly those from indigenous communities and minority-serving institutions, enhancing representation within the environmental sciences.

AD Osherman Scholarship

Benefiting first-generation students in Texas.

Funding

Four (4) scholarships awarded out:

• $3,500 for students pursuing a 4-year degree
• $2,500 for students pursuing a 2-year degree

One-time award. Previous recipients may reapply as long as all eligibility requirements are met.

The ASTRO-PCF Young Investigator Award, a collaboration between the Prostate Cancer Foundation and the American Society for Radiation Oncology, supports early-career researchers in prostate cancer. It offers $225,000 over three years to young investigators under 35, enabling them to further their research and career. Awardees are required to participate in the Annual PCF Scientific Retreat and Young Investigator Forum, fostering a community dedicated to advancing the field of radiation oncology.

Camillo Family Scholarship 

Benefiting dependents of Camillo Properties, Camcorp Entities, or LCI Services employees.

The Camillo Family Scholarship was created to provide dependents of employees of Camillo Companies (Camillo Holdings, LCI Services, Legend Homes, Millmark Capital, and SimplyHome) with scholarships to further their education.

This is a renewable scholarship, meaning recipients can renew the award and claim up to 4 years of funding if they meet the GPA and enrollment requirements and complete the renewal application for each academic year they plan to be enrolled.

Multiple scholarships awarded for the 2026-27 academic year. Award amount varies by college/degree type:

• 4-Year College/University - The scholarship is comprised of up to four annual awards of $5,000, for a total award of up to $20,000. The four annual awards may be received over a period of up to five years.
• 2-Year College/Trade School - The scholarship award is comprised of up to two annual awards of $2,500, for a total award of up to $5,000. The two annual awards may be received over a period of up to three years.

What can the scholarship be used for?

The scholarship will be mailed directly to the student's college to be used towards tuition, required academic fees, and/or book expenses. 

Scholarship funding cannot be distributed directly to the student. 

The Big Country Athletic Hall of Fame Scholarship, established by the Community Foundation of Abilene, supports varsity athletes in the top 25% of their graduating class from specific counties. This scholarship honors outstanding high school athletes and coaches in the Abilene area, promoting academic and athletic excellence. Applicants must have participated in varsity sports during their junior and senior years and provide a recommendation from a varsity coach. This initiative aims to empower students to pursue their college education dreams.

Fuel Up

We’re Fuel Up – an initiative created by America’s Dairy Farmers to help meet the needs of schools across the country when it comes to fueling healthy bodies and healthy minds.

Fuel Up is all about educators, students and partners working together to make a difference in their schools and their communities.

Fuel Up is an initiative focused on helping educators and students fuel wellness in the areas that matter most, like being mindful and staying healthy. Our educational resources, partnerships and grant/funding opportunities aim to broaden access to good nutrition and overall wellness.

School Nutrition Equipment Grants

Nutrition equipment grants are now available through GENYOUth's End Student Hunger initiative, with applications now open in the new School Wellness Portal.

K-12 schools can apply for an equipment grant to help increase students' access to, and participation in, nutritious school meals.

Overview of Fuel Up Equipment Grant

• One of two nutrition equipment kits—each valued at $2,000—is available to qualified K-12 schools to improve access to nutritious foods.

• Your application must demonstrate how the funding will increase your students’ access to and their consumption of dairy products (milk, yogurt, cheese). Your local Dairy Council can help you with ideas for how to increase dairy.

• Applications will be evaluated based on a variety of factors, including school enrollment, student reach, in-school support, school location, and the sustainability of the proposed program. Consideration will be given to schools in underserved communities whose students are most at risk for poor nutrition and childhood obesity.

• You are encouraged to contact your local Dairy Council with questions about the application process. They can be especially helpful in suggesting ways to increase dairy consumption at your school.

Schools can visit the GENYOUth School Wellness Portal to review eligibility requirements, explore equipment options, and begin an application.  

The Greater Tindall Neighborhood Scholarship Fund, established by the Community Foundation of Central Georgia, aims to support residents of Tindall Heights pursuing post-secondary education. It offers $2,000 per recipient, renewable for up to four years. Eligible applicants must demonstrate financial need, maintain a minimum 2.0 GPA, and enroll full-time at an accredited institution. The scholarship fosters educational growth and community development, ensuring that residents have the necessary resources to succeed in their academic endeavors.

The Ovarian Cancer Research Program (OCRP) Investigator-Initiated Research Award aims to support impactful research addressing critical needs in ovarian cancer and patient care. It requires a robust research plan with preliminary data and allows for studies across all research phases, excluding clinical trials. A unique Partnering Principal Investigator option encourages collaboration between two PIs to enhance research outcomes beyond individual efforts, promoting innovation in the field of ovarian cancer.

Agog Open Call: Climate Futures + Immersive Media

This open call supports immersive media projects that help people better understand and respond to climate challenges and imagine what a better world could be.

We are looking for projects that use immersive technologies—including smart glasses, augmented reality, spatial sound, and mixed reality—to create more engaging, experiential forms of climate storytelling and civic participation.

The open call will support projects across a range of stages and formats, from early ideas to more developed work. What matters most is a compelling story or experience, a clear sense of purpose, and a thoughtful approach to bringing the work to life.

Grants may be awarded in denominations ranging from $25,000 to $200,000. In addition to funding, selected projects may receive mentorship, advisor support, and opportunities for partnership and distribution.

About Pfizer Grants

Pfizer supports the global healthcare community’s independent initiatives (e.g., research, quality improvement or education) to improve patient outcomes in areas of unmet medical need that are aligned with Pfizer’s medical and/or scientific strategies.

Pre-clinical Investigation of anti-TFPI-mediated Rebalancing Mechanisms in Non-Hemophilic Bleeding Disorders

There remains a scientific gap in understanding of the role of anti-TFPImediated hemostatic rebalancing in the context of inherited or non-hemophilic bleeding disorders. This competitive grant program encourages competitive submissions focsed on generating preclinical/foundational data exploring the therapeutic potential and mechanisms of TFPI modulation in bleeding disorders other than hemophilia.

Project Types and Area of Interest

Potential applicants are encouraged to identify and address preclinical/basic science data generation for TFPI modulation/rebalancing in their local setting. This may include:

• Rare bleeding disorders which arise from deficiencies in different clotting factors or pathway components but converge on a common functional endpoint which is an impaired thrombin generation (e.g., Factor II, Factor V, Factor VII, Factor X and Factor XI deficiencies, as well as von Willebrand disease).
• Other diseases such as Glanzmann's thrombasthenia (GT) that have a distinct pathophysiological mechanism.
• Other rare bleeding disorders whose mechanisms are not well understood (e.g., Bleeding Disorder of Unknown Cause, BDUC).

Society of Toxicology

Founded in 1961, the Society of Toxicology (SOT) is a professional and scholarly organization of scientists from academic institutions, government, and industry representing the great variety of scientists who practice toxicology in the US and abroad. The Society’s mission is to create a safer and healthier world by advancing the science and increasing the impact of toxicology. SOT operates under four guiding principles:

• Serving the needs of the scientific discipline and our members to enhance human, animal, and environmental health.
• Life-long learning and intellectual scientific stimulation.
• Diversity of representation in all activities of the Society.
• Integrity.

BMSS Perry J. Gehring Biological Modeling Endowment Award

The Biological Modeling Specialty Section (BMSS) will present the Perry J. Gehring Biological Modeling Award at the BMSS Business Meeting and Reception during the SOT Annual Meeting. This award is made possible by the Perry J. Gehring Biological Modeling Award Fund of the SOT Endowment, and it will consist of a plaque and a cash award.

Research areas of interest include all aspects of biologically based modeling and simulation, including but not limited to: modeling of complex biological systems, biological insights gained through model development and application, model validation, and mathematical/statistical/computational approaches to biological modeling.

Applicants for this award will be considered for all BMSS awards for which graduate students and postdoctoral scholars are eligible.

About Legacy Foundation

Legacy Foundation is the community foundation for Lake County, Indiana. We connect people, knowledge, and funding to build an equitable, accessible, and inclusive Lake County, now and for generations to come.

Legacy Foundation is supported by a broad base of individuals, families, and businesses connected by the desire to improve Lake County, Indiana. With a growing portfolio of over 300 funds and approximately $80 million in assets, Legacy Foundation is a trusted source for philanthropic giving in the region.

For over 30 years, Legacy Foundation has been empowering people, providing strategic leadership, and impactful philanthropic support to create an equitable Lake County where all people thrive.

Mission Statement

Transforming Lake County by providing strategic leadership and impactful philanthropic support to ensure equitable opportunity for all communities that we serve.

Vision Statement

Create an equitable Lake County where all people thrive.

Lake County Athletic Officials Association Scholarship

Use the chart below to see which scholarships are the best fit for you! You must complete the Legacy Universal Application to apply.

Scholarship eligibility requires students to attend an accredited 2 or 4 year public or private institution of higher learning. All scholarships are for full-time students, unless otherwise noted. Renewable awards are for 4 years of undergraduate study and cannot be used for post graduate coursework; all awards are paid directly to the school or may be used for book reimbursement.

The Ham Family Scholarship Fund, established by Stephanie and CJ Ham along with Essentia Health and the NFL Foundation, supports diverse students in Duluth and Superior. Created to enhance BIPOC retention and graduation rates, it offers $1,000 annually for up to four years. Eligible applicants must identify as BIPOC, demonstrate financial need, maintain a GPA of 2.5 or higher, and engage in extracurricular activities. This scholarship aims to empower students in their pursuit of higher education.

Residential Substance Abuse Treatment for State Prisoners (RSAT) Program

Overview

The Residential Substance Abuse Treatment (RSAT) Program is a formula grant program that enhances the capabilities of state, local, and tribal governments to provide residential substance use disorder (SUD) treatment to adult and juvenile populations during detention or incarceration, initiate or continue evidence-based SUD treatment in jails, prepare individuals for reintegration into the community, and assist them and their communities throughout the reentry process by delivering community-based treatment and other recovery aftercare services.

The RSAT Program encourages the establishment and maintenance of drug-free prisons and jails and development and implementation of specialized residential SUD treatment for individuals with co-occurring mental health and substance use disorders. The program also encourages the inclusion of medication-assisted treatment as part of any SUD treatment protocol.

Bureau of Justice Assistance

The Bureau of Justice Assistance (BJA) was created in 1984 to reduce violent crime, create safer communities, and reform our Nation’s criminal justice system.

BJA strengthens the Nation’s criminal justice system and helps America’s state, local, and tribal jurisdictions reduce and prevent crime, reduce recidivism, and promote a fair and safe criminal justice system. BJA focuses its programmatic and policy efforts on providing a wide range of resources, including training and technical assistance, to law enforcement, courts, corrections, treatment, reentry, justice information sharing, and community-based partners to address chronic and emerging criminal justice challenges nationwide. 

FY25 Residential Substance Abuse Treatment (RSAT) for State Prisoners Training and Technical Assistance Program

Executive Summary

This NOFO will provide training and technical assistance (TTA) to state and local grantees of the Residential Substance Abuse Treatment (RSAT) for State Prisoners Program to enhance implementation of comprehensive residential substance use treatment during detention or incarceration and aftercare services to prepare individuals for successful reintegration into the community. The selected TTA provider will also maintain and update the RSAT TTA website to serve as single source of information for RSAT grantees that reflects evolving needs and emerging evidence-based approaches.

The Veterans Treatment Court Program Enhancement Grant aims to bolster the operations of veterans treatment courts (VTCs) that serve veterans involved in the justice system. By addressing substance use and mental health disorders, these courts facilitate access to essential treatment services, reducing recidivism and overdose fatalities. The grant supports jurisdictions in enhancing their VTC capacity, improving service quality, and ensuring veterans receive the necessary support for long-term recovery. Funding of up to $1,000,000 is available for eligible jurisdictions.