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Best Operating Grants for Nonprofits in New York

Find the perfect Operating grants for nonprofits in New York on Instrumentl. 10,000+ Operating grants for nonprofits in New York in the United States.

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$2.80B

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$5K

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10,000+ grants
$2.80B total
$5K median

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10,274 Results based on applied filters

ESA Youth Scholarship Program

Electronic Security Association
Association/Society
United States
US $2,500 - US $15,000
The ESA Youth Scholarship Program, by the Electronic Security Association, provides financial support to children of first responders, having awarded over $941,500 to date. Eligible applicants are high school seniors with parents who are full-time active first responders. Each scholarship winner receives $1,000 and a chance to compete for larger awards of $14,000 for first place and $5,000 for second place. Applications are welcomed from students in participating states.
Emergency Medical Care & Services Academic Scholarship Programs First Responders

NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (UG3/UH3 Clinical Trial Optional) (357256)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH StrokeNet initiative invites applications for clinical trials and biomarker studies aimed at stroke treatment, recovery, and prevention. This funding opportunity encourages collaborative projects that validate promising interventions and scientific aims within the NIH StrokeNet framework. Key deadlines for submissions span from February 2025 to November 2026, with support provided by the National Coordinating Center and Regional Coordinating Centers to ensure efficient study implementation and participant recruitment.
Stroke

NIGMS Institutional Biomedical Undergraduate Research Training Program

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIGMS Institutional Biomedical Undergraduate Research Training Program aims to enhance the training of undergraduate students in biomedical research. By supporting institutions with limited NIH funding, the program provides trainees with 2–3 years of full-time research training. This initiative fosters a skilled workforce prepared for advanced biomedical degrees, addressing national health-related research needs through comprehensive educational and developmental programs.
Biology Biotechnology Biochemistry +2 more

Applied regulatory science research to evaluate and treat cardiotoxicity of oncology therapeutics

US Department of Health & Human Services: Food and Drug Administration (FDA)
Federal Government
United States
Unspecified amount
This grant aims to enhance applied regulatory science research for the evaluation and treatment of cardiotoxicity associated with oncology therapeutics. The initiative will facilitate collaboration with the FDA to develop effective methodologies and solutions, ensuring that research outcomes are directly relevant to regulatory decision-making. Key activities include regular communication with funded investigators and a focus on improving detection and management of cardiotoxicity, ultimately leading to impactful publications and presentations.
Cancer / Oncology Drug Safety

The Walt Secord “Always Sunny and 75” Memorial Trade Scholarship

Midlands Community Foundation
Private
United States
US $1,000

About Us

Midlands Community Foundation (MCF) is here to serve and add value to donors’ philanthropic needs by providing them an opportunity to “invest in the power of community.” It is our goal to identify current and emerging issues, channel resources to address community needs, and help prepare for the future.

MCF Mission

The mission of Midlands Community Foundation is to be a catalyst for lasting impact in Sarpy and Cass counties and to give opportunities to organizations and individuals to pursue their charitable goals.

Scholarships Through MCF

Midlands Community Foundation is committed to the futures of communities in Sarpy and Cass Counties, and across the country. Supporting higher education of students is a direct investment in the futures of these communities.

The Walt Secord “Always Sunny and 75” Memorial Trade Scholarship Application

The Fund shall annually distribute two (2) scholarships in the amount of $1,000 each.

Vocational & Trade Education Apprenticeship & Internship Programs Educational Access & Equity

AO Spine NA: Young Investigator Research Grant Award

Ao North America Inc
Private
North America
US $20,000
The AO Spine NA Young Investigator Research Grant Award supports early-career surgeons and researchers focusing on clinically relevant spinal or spinal cord research. With funding of $20,000, this initiative encourages new investigators by providing essential start-up capital. Successful applicants are required to present their findings at the Annual AO Spine North America Fellows Forum and submit progress and final reports detailing their research outcomes. This grant aims to foster innovation and excellence in spinal care.
Spinal Cord Injuries Medical Education & Professional Training Orthopedics

NEI Postbaccalaureate Opportunities in Vision Science (POVS) Research Education Program (R25 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $2,000,000
The NEI Postbaccalaureate Opportunities in Vision Science (POVS) Research Education Program aims to enhance the training of a diverse workforce in biomedical research. This initiative encourages recent college graduates from various backgrounds to gain hands-on research experience, particularly in vision science. The program supports educational activities focused on research experiences, ensuring participants are from a nationally recruited cohort. This funding opportunity is crucial for advancing the mission of the NEI and fostering inclusivity in scientific research.
Eye Diseases & Disorders Vision Impairment Care & Services

Community Support - Fundraising Events and Giveaway Donations

Bass Pro Shops & Cabelas Outdoor Fund
Private
Canada, United States
Up to US $2,500 in in-kind support
Bass Pro Shops & Cabela's Outdoor Fund supports conservation-focused nonprofits through fundraising events and donation of merchandise or gift cards. Organizations eligible for funding must be registered 501(c)(3) entities in the U.S. or provincially registered nonprofits in Canada. This initiative aims to connect communities to outdoor activities while promoting wildlife conservation and support for military veterans. Grants of up to $1,000 are available to enhance local fundraising efforts.
Environmental Conservation Outdoor Recreation Outdoor Equity +1 more

KUH P30 Resource Core Center (P30 Clinical Trial Not Allowed)

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The KUH P30 Resource Core Center funding opportunity invites applications for centers aimed at enhancing research in Kidney, Urology, and Hematology diseases. These centers will provide essential resources, including data and tools, to the research community, fostering collaboration through a national network with the Center Coordinating Hub. This initiative by the National Institutes of Health aims to drive innovative research and shared expertise for improved health outcomes.
Kidney Diseases

KUH U24 Center Coordinating Hub (U24 Clinical Trial Not Allowed)

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The KUH U24 Center Coordinating Hub aims to foster collaboration among funded Centers within the NIDDK/KUHN mission. This initiative encourages the development and sharing of vital research resources, including data, reagents, and expertise, with the broader scientific community. By creating a national network, the program enhances research capabilities and promotes innovative solutions in kidney, urology, and hematology diseases.
Kidney Diseases

NIDDK Multi-Purpose Resource-Related, Multi-Component Research Services Centers Cooperative Agreement (U2C - Clinical Trial Optional)

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIDDK Multi-Purpose Resource-Related Research Centers Cooperative Agreement (U2C) invites applications to enhance research capabilities in areas such as obesity and diabetes. These centers provide specialized services, including technical support and data coordination, primarily to clients at other institutions lacking necessary expertise. This initiative aims to bolster high-impact research through collaboration and experiential training, addressing critical health challenges aligned with NIDDK's mission.
Kidney Diseases

Radiation Oncology Certified Nurse (ROCN™) Exam Scholarship

Oncology Nursing Society
Private
American Samoa, Canada +5 more
Unspecified amount

Oncology Nursing Foundation

The mission of the Oncology Nursing Foundation is to support cancer nursing excellence.

Since 1981, the Oncology Nursing Foundation(ONF), through generous contributions from individuals and institutions, has provided more than $33 million in funding to support oncology nursing education, research and leadership development. This funding has translated to career development awards, academic scholarships, research grants, a myriad of specialized educational initiatives, as well as nurse resiliency support. The Foundation’s activities have played a critical role in improving patient care and advancing the oncology nursing profession.

Radiation Oncology Certified Nurse (ROCN™) Exam Scholarship

Recipients receive funding to cover the ONCC ROCN™ Certification exam fee.

Purpose

To support registered oncology nurses who specialize in providing care for adult or pediatric patients with cancer undergoing radiation therapy by providing funding support to cover the ROCN™ Certification exam fee. 

Cancer / Oncology Nursing

Open Ocean Research Grant Program

Global Fishing Watch Inc
Private
Algeria, Andorra +155 more
Up to US $20,000
The Open Ocean Research Grant Program, funded by Global Fishing Watch Inc, aims to enhance ocean governance through data sharing on human activity at sea. It invites researchers to improve technologies for better governance, offering up to $10,000 for individuals and $20,000 for small groups. This initiative strengthens the community of practice and optimizes Global Fishing Watch datasets to maximize their impact on ocean conservation efforts.
Oceanography Marine / Ocean Conservation Marine Biology

Peer Education Grant

Organization For Autism Research
Private
United States
US $500 - US $10,000
The Peer Education Grant, offered by the Organization for Autism Research, aims to enhance autism acceptance among children by providing educational resources and funding for initiatives. Grants of up to $10,000 support school-wide projects, with smaller grants available for other activities. Eligible applicants include educators and community organization leaders focused on autism awareness, particularly in low-income areas. This initiative fosters inclusive relationships and understanding between children and their autistic peers.
Autism

Jacqueline Hall Minet Travel Award for Cross-Cultural Understanding

Rochester Area Community Foundation
Private
United States
Up to US $2,000

Jacqueline Hall Minet Travel Award for Cross-Cultural Understanding

To provide financial assistance to a Brighton High School student or a Rochester City School District high school student so that he or she can participate in a travel experience that offers significant opportunities for involvement in a foreign-language culture.

Number and Size of Awards

Number of recipients and award amounts vary; maximum $2,000.

Allowed Use of Award

Awards may be used for expenses associated with travel abroad programs.

Education - Higher Education Career / College Preparation Language Education

Interventions to Address Disparities in Liver Diseases and Liver Cancer (R01 - Clinical Trials Optional) (357550)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This initiative aims to support research interventions targeting disparities in liver diseases and liver cancer among underserved populations in the U.S. It encourages innovative approaches to reduce health inequities and improve health outcomes. The funding opportunity is available through various deadlines for both standard and renewal applications, promoting multi-level strategies to address these critical health issues effectively.
Cancer / Oncology Liver Disease Health Disparities & Social Determinants of Health

Dr. Jeffrey Hanson Memorial Scholarship

Rochester Area Community Foundation
Private
United States
US $2,750

Dr. Jeffrey Hanson Memorial Scholarship

To support those pursuing careers in medicine, particularly primary care. 

Number and Size of Awards

One award of $2,750; paid in one lump sum in the Fall and divided equally between the Fall and Spring semesters.  

Allowed Use of Award

Awards may be used for tuition, fees, books, and other expenses associated with higher education.

Education - Higher Education Medical Education & Professional Training Primary Health Care

JPF Principal Grant Program RFP

Jacques Pepin Foundation
Private
United States
Up to US $10,000
The Jacques Pepin Foundation (JPF) is dedicated to advancing culinary arts education by supporting community kitchens that provide culinary training to individuals facing employment barriers. Grants of up to $10,000 are available for nonprofits to enhance their culinary programs, including operating costs and facility improvements. Eligibility extends to organizations funded in prior cycles, those that applied but were not funded, and newcomers to JPF funding. This initiative aims to empower underserved communities through culinary skills.
Workforce Preparation & Job Readiness Culinary Arts

GSSI Pathways in Sports Science Award | Graduate Student Research & Mentorship Award

American College Of Sports Medicine Foundation Inc
Private
United States
US $4,000 - US $6,000

American College Of Sports Medicine Foundation Inc

ACSM is the largest sports medicine and exercise science organization in the world, with nearly 50,000 international, national and regional members and certified fitness professionals.

Our Mission: To educate and empower professionals to advance the science and practice of health and human performance.

GSSI Pathways in Sports Science Award | Graduate Student Research & Mentorship Award

GSSI celebrates the passion, resilience, and academic excellence of first-generation college students pursuing graduate degrees in exercise physiology, sports science, kinesiology, and/or sports nutrition. Designed to empower emerging leaders in the field, the award recognizes individuals who are breaking new ground, not only in their families but in the science of human performance.

In addition to research funding, to help promote professional development, award winners will receive one year of 1:1 mentorship from a GSSI scientist. Award winners will also receive complementary registration to ACSM’s 2027 Annual Meeting in Indianapolis, IN.

ACSM requires award winners to:   

  • Submit official transcripts if selected as an award winner, 
  • Attend the 2027 ACSM Annual Meeting in Indianapolis, IN. 
  • Present funded research at a future ACSM Annual Meeting, and   
  • Send ACSM a copy of any publications or presentations related to the funded research. 
Education - Higher Education Kinesiology & Sports Medicine Tutoring & Mentoring

NIMH Career Transition Award for Tenure-Track Intramural Investigators (K22 Independent Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $600,000
The NIMH Career Transition Award (K22) supports tenure-track intramural investigators at NIMH in their transition to independent research faculty positions. This program aims to foster innovative research in mental health, encouraging applicants with a strong record of research excellence. Key deadlines for applications vary, including those for standard and renewal submissions, emphasizing the importance of timely applications to secure funding and advance mental health research initiatives.
Biology Health & Medicine Medical Education & Professional Training +1 more

CLRA Research Grant Program

Childrens Leukemia Research Assn Inc
Private
United States
Up to US $30,000
The CLRA Research Grant Program, led by the Children’s Leukemia Research Association, focuses on funding innovative research aimed at uncovering the causes of leukemia and improving treatment options. Grants totaling $30,000 are awarded to U.S.-based researchers, with the intention of advancing scientific understanding and ultimately finding a cure. The program has made significant contributions to the high cure rates for childhood leukemia, showcasing the importance of continued research in this field.
Leukemia

REI Cooperative Action Fund Grant

Rei Cooperative Action Fund
Private
United States
Unspecified amount
The REI Cooperative Action Fund Grant supports U.S.-based organizations that align with its mission to serve communities, particularly those connecting historically excluded individuals to the outdoors. The fund prioritizes initiatives that promote equitable access to outdoor spaces, enhance community health through nature, and create inclusive outdoor experiences. Eligible applicants must have a 501(c)(3) status and demonstrate a commitment to these values. However, individuals and certain organizations are not eligible for funding.
Outdoor Equity Outdoor Recreation Healthy Habits & Behaviors +1 more

LCRF | AstraZeneca Research Award on Strategies Using Patient Advocacy to Improve Outcomes in Small Cell Lung Cancer

Lung Cancer Research Foundation
Private
United States
US $250,000

The grant mechanism will focus on furthering the development of strategies towards improving the outcomes of Small Cell Lung Cancer (SCLC) patients through patient advocacy. Work supported through this mechanism will address important areas of need across the entire care continuum and have the immediate potential to increase research efforts, quality of life and survivorship. The overarching theme of the proposals should be centered around using patient advocacy as a tool to develop strategies toward improving outcomes for patients with SCLC. We will encourage applications on a wide variety of topics related to SCLC, including but not limited to the following:

  • Patient-Centric Care Models
    • Develop and implement care models that prioritize patient needs and preferences, integrating innovative approaches from diagnosis through survivorship
  • Advanced Screening and Diagnostic Technologies
    • Create comprehensive survivorship care plans addressing long-term healthcare needs, focusing on follow-up care, monitoring for recurrence, and managing chronic side effects
  • Access and Equity
    • Investigate barriers to accessing quality care, clinical trials, screening and biomarker testing for SCLC patients and purpose solutions to ensure equitable healthcare delivery for diverse populations

    • Technology Integration
      • Explore the use of digital health tools and technologies to facilitate better patient-provider interactions, personalized care, and continuous monitoring during the care continuum
    • Patient Feedback Mechanisms
      • Establish robust feedback systems to gather patient insights and experiences and use this data to inform continuous improvements in care delivery, diagnostic technologies, treatment approaches, clinical protocols and accessible repositories to facilitate broad research collaboration

      The 2026 Strategies Using Patient Advocacy to Improve Outcomes in Small Cell Lung Cancer will grant a minimum of one award of $250,000 for a period two years ($125,000 per year).

      Lung Cancer

      AISES National Conference Travel Scholarship

      American Indian Science and Engineering Society (AISES)
      Association/Society
      United States
      Unspecified amount
      The AISES National Conference Travel Scholarship provides financial support for full-time students in STEM fields to attend the annual conference. Covering registration, airfare, and lodging, recipients must commit to attending all events and uphold the AISES Code of Conduct. Selection is based on the quality of essays, letters of recommendation, and academic performance. Announcements for awarded scholarships will be made in late August/early September 2025, facilitating networking and professional development for indigenous students.
      Academic Success & Enrichment STEM / STEAM Education Indigenous Services

      Lee Essie and Charlie McMillan, Jr. Scholarships: Music Scholarship

      Saginaw Community Foundation
      Private
      United States
      Unspecified amount

      Scholarships

      Since awarding our first $500 scholarship in 1987, the Saginaw Community Foundation has awarded college scholarships to area students totaling more than $13.7 million, thanks to our generous donors. Each year, over 500 college-bound or career and technical education students benefit from our scholarship awards.

      Our single application process makes it easy to potentially qualify for one or more of our 260+ scholarships.

      Music Scholarship

      At a very early age in Alabama, Lee Essie Smith was a self-taught musician. After losing her mother as a young teenager, she began putting her God-given musical talent to work as a pianist for several churches. By the time she graduated from high school, she had learned the cosmetology trade and met Charlie McMillan, Jr.

      After his wife’s death, Mr. McMillan continued his community service with the Democratic Party, Habitat for Humanity and Mt. Olive Baptist Church as an usher. Although he did not serve very long in the military, Mr. McMillan continues to exemplify the values and physical energy of the “Army Strong” slogan. He is the patriarch of the family – always dapper – and a regular attendee at church services.

      Education - Higher Education Vocational & Trade Education Music

      Exhibitions Abroad Support Grant Program

      Japan Foundation, New York
      Private
      Africa, Americas +14 more
      Unspecified amount
      The Exhibitions Abroad Support Grant Program, initiated by the Japan Foundation in New York, offers financial aid to U.S. museums and art institutions organizing exhibitions that showcase Japanese art and culture internationally. This program supports a range of events, including biennials and triennials featuring Japanese artists. Eligible applicants are non-profit organizations from designated states, with a focus on promoting cultural exchange and understanding through art.
      Asian Art Asian / Pacific Island Culture & Heritage

      Athene Charitable Foundation Grants

      Athene Charitable Foundation
      Private
      United States
      Unspecified amount
      The Athene Charitable Foundation focuses on corporate social responsibility through community involvement, aiming to create positive social impacts in education, health, human services, and the environment. Their initiatives include partnerships, employee volunteering, and donations aligned with their mission. They prioritize organizations that support diversity and inclusion while ensuring compliance with their non-discrimination policies. Eligible entities must be registered 501(c)(3) organizations or equivalent, enhancing community welfare where Athene employees live and work.
      Education Wellness & Healthy Living Human & Social Services +1 more

      Operating Grants for Nonprofits in New York Highlights

      Looking for operating grants for nonprofits in New York?


      Read more about each grant below or start your 14-day free trial to see all operating grants for nonprofits in New York recommended for your specific programs.

      Last updated: October 5, 2026. Next update: November 1, 2026.

      Grant Insights : Operating Grants for Nonprofits in New York

      Grant Availability

      How common are grants in this category?

      Common — grants in this category appear regularly across funding sources.

      300+ Operating grants for nonprofits in New York grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

      100+ Operating grants for nonprofits in New York over $25K in average grant size

      100+ Operating grants for nonprofits in New York over $50K in average grant size

      38 Operating grants for nonprofits in New York supporting general operating expenses

      200+ Operating grants for nonprofits in New York supporting programs / projects

      1,000+ Grants on Instrumentl focused on Workforce Preparation & Job Readiness

      1,000+ Grants on Instrumentl focused on Academic Success & Enrichment

      Grant Deadline Distribution

      Over the past year, when are grant deadlines typically due for Operating grants for Nonprofits in New York?

      Most grants are due in the third quarter.

      Q1
      26.5%
      Q2
      21.7%
      Q3
      27.4%
      Q4
      24.4%

      Typical Funding Amounts

      What's the typical grant amount funded for Operating Grants for Nonprofits in New York?

      Grants are most commonly $52,500.

      $300 $300 Min.
      $52,500 $52.5 K Median
      $870,598 $870.6 K Average
      $40,331,313 $40.3 M Max.

      Average Grant Size

      What's the typical amount funded for New York?

      Grants are most commonly $123,825.

      $123,825

      Total Number of Grants

      What's the total number of grants in Operating Grants for Nonprofits in New York year over year?

      In 2024, funders in New York awarded a total of 270,645 grants.

      2022 258,176

      2023 259,835

      2024 270,645

      Top Grant Focus Areas

      Among all the Operating Grants for Nonprofits in New York given out in New York, the most popular focus areas that receive funding are Philanthropy, Voluntarism & Grantmaking Foundations, Education, and Human Services.

      1. Philanthropy, Voluntarism & Grantmaking Foundations

      2. Education

      3. Human Services

      Funding Over Time

      How is funding for Operating Grants for Nonprofits in New York changing over time?

      Funding has increased by 16.44%.

      2022 $28,202,880,598

      2023 $28,659,853,906
      1.62%

      2024 $33,370,589,734
      16.44%

      New York Counties That Receive the Most Funding

      How does grant funding vary by county?

      New York County, Kings County, and Nassau County receive the most funding.

      County Total Grant Funding in 2024
      New York County $21,403,401,202
      Kings County $2,517,718,693
      Nassau County $2,484,899,697
      Tompkins County $2,194,408,740
      Rockland County $1,906,062,935