Best Grants for Capital Funding in North Carolina

Asia-Pacific Network for Global Change Research

The Asia-Pacific region, home to over half the world's population, faces challenges due to its development goals, which strain natural resources, communities, and cultural heritage. These issues are exacerbated by adverse environmental changes. While research has shed light on these problems, it's clear that more challenges lie ahead. The Asia-Pacific Network for Global Change Research (APN) is well-positioned to generate new knowledge and solutions for these evolving global change and sustainability issues by supporting collaborative research and scientific capacity development activities, particularly those aimed at training the next generation of early career professionals.

APN 2025 Call for Proposals: CAPaBLE Programmes

CAPaBLE, our scientific capacity development programme, aims to enhance the capacity of scientists, policymakers and practitioners to assess global change issues, and explore options to resolve issues towards achieving sustainability. Through CAPaBLE, we support activities that enhance capacity at individual, organizational and systemic levels.

Activities of interest under the CAPaBLE Programme

APN supports CAPaBLE activities that enhance existing capacities of developing countries at three levels of individual-based capacity development; group, organisation, network-based capacity development; and societies, governance, and system level capacity development. APN accepts CAPaBLE proposals that engage 1 or more member/approved countries. Proposals must address one or more of the following activities:

SCIENTIFIC CAPACITY DEVELOPMENT ACTIVITIES that promote the following approaches related to one or more of the six thematic areas of APN:

• Utilising and strengthening existing capacity, 
• Creating opportunities to use/instil capacity, 
• Developing new capacity through innovative approaches.

AWARENESS-RAISING AND DISSEMINATION activities through policy- and decision-making communities, civil society, and/or the general public.

SCIENCE-POLICY interfacing in the context of the priority topics.

CAPACITY DEVELOPMENT PARTNERSHIP ACTIVITIES that contribute to the capacity development components of the evolving global change arena, including the UNFCCC Paris Agreement, IPCC, IPBES, post-2015 Sustainable Development Goals, Sendai Framework for Disaster Risk Reduction, and the UN Decade of Ocean Science, and ongoing and new global change and sustainability research programmes.

Activities geared towards using SCIENCE COMMUNICATION to disseminate knowledge generated from projects, particularly to non-science audiences.

The Rotary Club of Burgaw Scholarship Endowment, managed by the North Carolina Community Foundation, supports Pender County residents pursuing higher education in North Carolina. This scholarship particularly favors students attending community colleges and those from local high schools. Emphasizing financial need, it aims to foster educational opportunities for deserving individuals, ensuring they have access to the resources needed for academic success and community contribution.

About PCORI

PCORI funds patient-centered comparative clinical effectiveness research (CER).

Our Mission

PCORI helps people make informed healthcare decisions, and improves healthcare delivery and outcomes, by producing and promoting high-integrity, evidence-based information that comes from research guided by patients, caregivers, and the broader healthcare community.

Broad Pragmatic Studies PCORI Funding

The Patient-Centered Outcomes Research Institute (PCORI) intends to issue a Broad Pragmatic Studies (BPS) PCORI Funding Announcement (PFA), seeking to fund patient-centered comparative clinical effectiveness research (CER) projects. 

Research Initiative Highlights

CER compares at least two available health treatments, services or care delivery strategies. PCORI seeks proposals that compare clinical interventions (e.g., pharmacological and nonpharmacological treatments, screening and diagnostic approaches) and healthcare delivery system interventions (e.g., workforce, technologies, healthcare service delivery designs) to evaluate potential benefits and harms of different treatment and care delivery options, thus generating evidence that empowers patients, caregivers and the broader healthcare community with information to make informed choices that reflect their needs and preferences.

Special Areas of Emphasis

For Cycle 2 2026, PCORI is particularly interested in submissions that address the following Special Areas of Emphasis (SAE) within the BPS funding opportunity. The purpose of identifying these SAEs is to encourage submissions to these areas, rather than limiting submissions to these topics. Applicants addressing one of the below SAEs should identify the area that is best associated with their research approach:  

• Addressing Obesity
• Diabetes Prevention, Care and Treatment
• Management of Urogynecological and Pelvic Pain
• Pain Management for Individuals Living With Sickle Cell Disease

In PCORI-funded research, patients and other research partners are expected to meaningfully contribute their lived experience or professional expertise to ensure studies are patient-centered, relevant and useful for healthcare decision making. Applicants must address PCORI’s Foundational Expectations for Partnerships in Research — an evidence-based framework supported by tools and resources to guide effective engagement strategies. Applicants are also strongly encouraged to consider the inclusion of a broad range of patient-centered burdens and economic outcomes. 

Broad Pragmatic Studies PFA: Category 1, Category 2 and Category 3 Study Specifications

PCORI will commit up to $120 million in direct costs through this funding opportunity. This funding opportunity contains three categories for funding:

• Category 1: Category 1 will support research projects with direct costs up to and including $5 million.

• Category 2: Category 2 will support research projects with direct costs greater than $5 million and up to a maximum of $12 million. Applications for funding under Category 2 will be required to provide additional information in the Letter of Intent (LOI) and application to justify the size and scope of the proposed research projects and to explain how additional funds are necessary with respect to the scale, scope and complexity of personnel and material resources needed to address the research question.

• Category 3: Category 3 will support research projects with direct costs up to $12 million that utilize PCORnet® to conduct observational studies and/or pragmatic trials that are national in scale. Category 3 PCORnet Studies® must include two or more Clinical Research Networks and share study progress, performance metrics and best practices with the network to promote continuous learning and improvement. PCORnet Studies® will leverage the PCORnet Common Data Model® as appropriate. Additional details about Category 3 can be found on the PCORI website.  

The Area Development Grant Program, managed by the Appalachian Regional Commission (ARC), supports economic growth in Appalachia through investments in critical infrastructure and workforce development. Targeting 423 counties across 13 states, the program encourages local communities to collaborate with state governments to identify and implement impactful projects. Key focus areas include enhancing utilities, promoting entrepreneurship, and strengthening local leadership. This initiative aims to uplift the 26 million residents of Appalachia, fostering sustainable economic opportunities.

The Norfolk Southern Trades on Track SkillPointe Scholarship offers $5,000 scholarships for students pursuing trades education related to the rail industry. Eligible candidates must be enrolled in a post-secondary institution and focused on railway-related trades. With over 1,000 scholarships funded and a mission to close the skills gap, this initiative empowers individuals towards high-demand careers without requiring a four-year degree, ultimately strengthening the workforce and economy.

The Russell Glenwood Baldwin Scholarship supports graduating seniors from Brunswick County, NC, pursuing higher education in state. Ideal candidates are those from Leland, NC, and those focusing on natural health, nutrition, or organic farming. The scholarship considers character, academic dedication, and financial need. Applications open on Dec. 16, 2025, and close on March 3, 2026. Preference may be given to students from Pungo Christian Academy or those who have served as volunteer firefighters.

The NC Alpha Delta Kappa Student Achievement Scholarship supports North Carolina high school seniors pursuing education degrees. Eligible applicants should have a GPA between 2.5 and 3.5 and SAT scores ranging from 900 to 1050. The selection committee considers academic performance, community service, integrity, and leadership potential. Applications will be accepted from December 16, 2025, to March 3, 2026, providing a valuable opportunity for future educators to advance their studies.

The CASL Scholarship Fund in Memory of Lane Meyer, managed by the North Carolina Community Foundation, awards scholarships to high school seniors actively participating in the Capital Area Soccer League at the Challenge Level or above. Applicants are evaluated on their academic excellence, soccer skills, sportsmanship, and community involvement, reflecting the values exemplified by Lane Meyer. This initiative not only honors Lane's legacy but also fosters leadership and teamwork among young athletes across North Carolina.

The Jecholiah Dinkins Hollar Legacy Scholarship, offered by the North Carolina Community Foundation, supports high school graduates from Yadkin County pursuing undergraduate degrees at private colleges in North Carolina. Preference is given to those attending Duke University. Selection is based on academic achievement, moral character, and community service. Established in honor of Jecholiah Dinkins Hollar, this scholarship emphasizes the importance of education and fostering a love of learning for future generations.

The Larry and Diane Stone Scholarship Endowment, established by the North Carolina Community Foundation, supports Wilkes County high school seniors pursuing higher education within the University of North Carolina system. This initiative aims to empower local students by providing them with essential financial assistance, thereby fostering academic achievement and community development. The Foundation's commitment to philanthropy ensures that resources are allocated effectively to meet the educational needs of students across North Carolina.

The Film and Entertainment Grant from the North Carolina Department of Commerce supports filmmakers in the state by offering financial assistance for qualifying productions. Eligible projects include television series, feature films, and commercials that meet specific spending requirements. Grants can reach up to $15 million for series and $7 million for films, encouraging the growth of the local film industry. North Carolina's favorable production environment enhances opportunities for filmmakers.

Service Objects In-Kind Grants support non-profit organizations dedicated to environmental conservation and sustainability. By leveraging their data validation services, they aim to assist projects that promote ecological health and responsible resource management. The program prioritizes applications with clear, measurable objectives and impactful outcomes within one to three years. Organizations with 501(c)(3) status in the U.S. are eligible, while initiatives lacking detailed plans or focusing on generalized education will not qualify. This grant fosters community involvement in environmental stewardship.

The Mebane Foundation Grant focuses on enhancing educational opportunities for children by ensuring access to top-tier education for all, regardless of background. Emphasizing early reading skills as foundational, the grant promotes collaborations among educators, business leaders, and the community to foster innovative solutions. Organizations eligible for funding must be 501(c)(3) exempt and not private foundations. The Foundation encourages proposals that include challenge matches and offers multi-year funding for new initiatives.

The Indian Education Formula Grants, funded by the U.S. Department of Education, aim to support the educational needs of American Indian and Alaska Native students. This program assists local educational agencies, tribes, and organizations in meeting state academic standards through various initiatives like after-school programs, tutoring, and enrichment activities. Eligible entities include certain local educational agencies, schools funded by the Bureau of Indian Education, and Indian organizations. Grants aim to supplement regular educational programs.

The Kassel Smit Make A Difference Scholarship, established by the Triangle Community Foundation, is designed to honor the legacy of Kassel Smit by recognizing graduating students from Cary High School who embody creativity, curiosity, and compassion. This non-renewable scholarship offers financial support for various educational expenses at accredited institutions, with no GPA or residency requirements, allowing deserving students to pursue their academic goals without barriers.

The Ernest Morgan Memorial Scholarship, managed by CommunityGiving, supports central Minnesota student athletes and leaders to pursue higher education outside their home states. This scholarship aims to expand students' horizons and experiences, with a total award of $5,000 available. Open to high school seniors from specific schools, applicants are encouraged to apply online and demonstrate their leadership or athletic skills. This initiative enhances educational opportunities and fosters personal growth among local youth.

The Albemarle-Pamlico National Estuary Partnership (APNEP) offers funding for projects focused on community engagement and stewardship aimed at enhancing environmental literacy and volunteerism in the Albemarle-Pamlico region. Grants typically range from $40,000 to $80,000, supporting initiatives that foster stewardship, promote outdoor experiences, and address environmental inequities, ensuring diverse community involvement in protecting local ecosystems.

The DeLeon Carter Foundation Grants support a wide range of charitable purposes, including religious, scientific, educational, and literary initiatives, as well as the prevention of cruelty to children and animals. This private foundation is committed to addressing the needs of the Rocky Mount and Nashville communities while maintaining flexibility in its decision-making processes. Eligible applicants must be tax-exempt under Section 501(c)(3) of the Internal Revenue Code.

The Ethnic Minorities and Women’s Internship Grant supports entry-level athletics administrative positions for one academic year, promoting diversity in NCAA Division II. It provides $30,000 for intern salaries and $3,000 for professional development, benefiting six schools annually from a total budget of $180,000. Eligible applicants must be active NCAA members, with a focus on enhancing ethnic minority and gender representation in athletics administration. This initiative encourages professional growth and compliance in diverse environments.

The Patient-Centered Outcomes Research Institute (PCORI) intends to issue a Broad Pragmatic Studies (BPS) PCORI Funding Announcement (PFA) on Aug. 4, 2026, seeking to fund high-impact, patient-centered comparative clinical effectiveness research (CER) projects. This preannouncement provides potential applicants additional time to identify collaborators; obtain patient and stakeholder input on potential studies; and develop responsive, high-quality applications. 

Patient-centered CER compares at least two available health treatments, services or care delivery strategies. PCORI seeks proposals that compare clinical interventions (e.g., pharmacological and nonpharmacological treatments, screening and diagnostic approaches) and healthcare delivery system interventions (e.g., workforce, technologies, healthcare service delivery designs) to evaluate potential benefits and harms of different treatment and care delivery options, thus generating evidence that empowers patients, caregivers and the broader healthcare community with information to make informed choices that reflect their needs and preferences. 

The Go Outside (GO) Grants provide North Carolina K-12 schools and nonprofit organizations funding for outdoor educational experiences, including field trips and visiting programs. With grants of up to $2,500, educators can enhance outdoor learning through activities involving aquariums, zoos, and STEM organizations. While applications are currently open, funding is contingent upon state funding availability, and applicants are advised to plan for dates no earlier than July 2025.

The Governor's Crime Commission Grants, under the Violence Against Women Act (VAWA-STOP), aim to enhance the support and protection for victims of domestic violence, sexual assault, dating violence, and stalking. Administered by the North Carolina Department of Public Safety, these grants foster community partnerships and effective responses to such crimes, thereby promoting a safer environment for all. The initiative aligns with the Office on Violence Against Women's goals to address these critical issues comprehensively.

The US Department of Health & Human Services, through the NIH, invites applications for innovative approaches to implement SBIRT/P for addressing alcohol, tobacco, and other drug use in adults facing health disparities. This funding opportunity encourages research that tests screening, brief interventions, and referrals for treatment or prevention services. Applications are due on specified deadlines from February 2024 through March 2027, fostering collaboration with healthcare and community partners to enhance public health outcomes.

The Building Reuse Program by the North Carolina Department of Commerce aims to revitalize older buildings for economic development. Grants are available for renovating vacant buildings, expanding existing business locations, and constructing health care facilities. This initiative supports local governments in transforming these structures into assets that attract new businesses and create jobs, particularly in rural areas. Eligible applicants include local governments in Tier 1 and Tier 2 counties, ensuring community development and sustainability.

The Watson-Brown Foundation Grant supports organizations dedicated to preserving the history and culture of the South. It offers various types of grants, including for educational programming and historic preservation, with a focus on southern studies. Eligible recipients include public charities in the southeastern United States. The Foundation's Junior Board of Trustees also awards grants to preservation projects in east central Georgia, emphasizing youth engagement in cultural heritage.

The Sidney B. Meadows Scholarship, established in 1989, offers financial support to students pursuing degrees in horticulture across 16 southeastern states. Administered by the Sidney B. Meadows Scholarship Endowment Fund, this scholarship honors the legacy of Sidney B. Meadows, a dedicated advocate for education in the horticultural industry. Applicants must meet specific eligibility criteria related to academic standing and residency, with preference given to those intending to work in the field after graduation.

The Abelard Foundation, established in 1958, supports progressive social change projects located east of the Mississippi River. With an average grant size of $12,000, they prioritize new initiatives with budgets under $350,000. The foundation emphasizes community organizing, civil rights, and empowering marginalized groups. Eligible applicants must be associated with a nonprofit organization and demonstrate a commitment to local leadership and broader policy connections. The board meets biannually to decide on approximately 15 grants per year, focusing mainly on general support.