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Best Operating Grants for Nonprofits in North Carolina

Find the perfect Operating grants for nonprofits in North Carolina on Instrumentl. 10,000+ Operating grants for nonprofits in North Carolina in the United States.

10,000+

Available grants

$2.70B

Total funding

$5K

Median grant

10,000+ grants
$2.70B total
$5K median

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9,788 Results based on applied filters

Alpha Delta Kappa Xi Education Scholarship

Community Foundation of Northern Illinois
Private
United States
Unspecified amount
The Alpha Delta Kappa Xi Education Scholarship supports graduate students pursuing careers in education. This scholarship aims to recognize and foster fellowship among educators, promoting educational excellence and altruism. By providing financial assistance, it encourages aspiring educators to achieve their goals and contribute to the field of education. Eligible applicants can complete a single online application to match with multiple scholarship opportunities, streamlining the application process.
Education Academic Scholarship Programs Social Justice / Human Rights +3 more

BioMarin Medical Education Grant

BioMarin
Corporate
North America
Unspecified amount
The BioMarin Medical Education Grant offers funding for educational activities aimed at enhancing the knowledge and skills of healthcare professionals. Eligible applicants include accredited providers, medical associations, and patient advocacy groups. The grant focuses on supporting initiatives related to rare diseases, ensuring timely access to treatments and education. Applications are accepted year-round, but a minimum of 60 days is required for review prior to events. This commitment underscores BioMarin's dedication to improving patient care and advancing medical knowledge.
Rare Diseases Hematological Systems Genetic Conditions & Birth Defects +1 more

Native Forward Direct Scholarship

Native Forward Scholars Fund
Association/Society
United States
Unspecified amount
The Native Forward Direct Scholarship supports American Indian and Alaska Native students by providing mid-year funding opportunities to alleviate educational costs. With over 50 years of experience, Native Forward has empowered more than 22,000 students from diverse backgrounds. This scholarship recognizes the limited access these students face in higher education and aims to enhance their academic journeys while fostering community engagement and mentorship through a strong alumni network.
Education - Higher Education Academic Success & Enrichment Native American Services +2 more

Rogers and Meredith Scholarship (College)

Central Carolina Community Foundation
Private
United States
Unspecified amount

About

Central Carolina Community Foundation is a nonprofit organization that helps generous people give back to the Midlands of South Carolina in ways that matter. Since 1984, we’ve been a trusted partner, helping individuals, families, and businesses make smart, meaningful contributions that support local nonprofits, scholarships, and community projects.

Rogers and Meredith Scholarship (College) ($4,000) 

This renewable scholarship is available to students who have been residents of Epworth Children’s Home, Thornwell Home for Children or students who’ve been in custody of the South Carolina Department of Juvenile Justice. 

Education - Higher Education Education - High School Academic Scholarship Programs +2 more

Leonard Litz Foundation-TransPLUS Resource Grants

Leonard Litz Foundation
Private
United States
Unspecified amount
The Leonard Litz LGBTQ+ Foundation, via its TransPLUS Resource Center, supports transgender, gender-nonconforming, non-binary, and intersex individuals. By providing grants and resources, the Foundation aims to address urgent needs in healthcare, housing, and legal services while fostering community connections. They build peer-support networks, publish updates, and support initiatives to empower TGNCNBI individuals and their allies, ensuring that marginalized voices are heard and uplifted.
Sexuality & LGBTQIA+ Rights LGBTQIA+ Services Intersex & Transgender Rights

NC Hunter and Jumper Association’s Norah Morris Memorial Scholarship Endowment

North Carolina Community Foundation Inc
Private
United States
More than US $1,000
The NC Hunter and Jumper Association’s Norah Morris Memorial Scholarship Endowment supports individuals pursuing higher education who have engaged in equestrian activities. Open to undergraduates, graduates, and adult re-entry students, the scholarship aims to assist those attending various educational institutions in the United States. Applications for NCCF scholarships will be accepted from December 16, 2025, to March 3, 2026. Be sure to check specific eligibility requirements for each scholarship.
Education - Higher Education Education - High School Academic Scholarship Programs +2 more

Edward P. Suchecki Family Scholarship

Grand Haven Area Community Foundation
Private
United States
Unspecified amount
The Edward P. Suchecki Family Scholarship, established by the Grand Haven Area Community Foundation, supports local high school senior athletes pursuing a business career. Named after Ed Suchecki, a dedicated coach and businessman who valued education, this scholarship prioritizes financial need and favors football and golf players. Applicants must submit their transcripts and other required documents. This initiative aims to empower young athletes to achieve their educational goals.
Education - Higher Education Educational Access & Equity Sports & Athletics +3 more

Transportation Research and Policy

Arnold Ventures
Private
United States
Up to US $200,000

Transportation Research and Policy

Arnold Ventures (AV) is a philanthropy dedicated to improving the lives of all Americans through evidence-based solutions that maximize opportunity and minimize injustice.

The Infrastructure team has been investing in efforts to build better, faster, and lower-cost infrastructure with a focus on housing, energy, and transportation. For transportation, we are investing in policymaking and research that tackles the inefficiencies that make U.S. transportation infrastructure so difficult and expensive to build. 

Purpose

Transportation policy represents an avenue for improving the systems moving people, goods, and services. The Infrastructure team is seeking proposals evaluating the effectiveness and/or benefits of existing transportation or transportation-adjacent policies on outcomes for communities in the United States.

Eligible Projects and Topic Areas of Interest

This Request for Proposals (RFP) aims to bolster the knowledge base of potentially effective policies, programs, and interventions by funding efforts that align with key AV Infrastructure policy areas.

AV is primarily focused on traditional surface transportation — road and public transit — but is open to proposals in aviation, maritime, passenger and freight rail, trucking, and more.

We seek proposals for: 1) research, expanded data sets, or analysis; 2) administrative or legislative policy reforms at the federal, state, or local level; or 3) models of effective implementation including proposals for implementing agencies to partner with researchers or program evaluators to conduct baseline and post-intervention research on implementation effectiveness that will advance the knowledge base and provide illustrative examples within, but not limited to, the following topic areas:

  • Transportation Capital Investment Reform. Evaluating how capital funding is prioritized and selected at the federal, state, or regional level, including discretionary grant programs and formula-based funding. What reforms could ensure projects deliver higher public returns?
  • Cost Estimation, Oversight, and Accountability. Why do major transportation projects frequently exceed budgets and timelines, and how can we identify strategies to improve transparency, cost realism, and performance oversight?
  • Access in Mobility Outcomes. Measuring how current transportation investments affect access to jobs, services, and economic opportunities for workers and families, and what policy changes could improve access.
  • Performance-Based Project Selection. How can public agencies shift from current, politically driven allocations to datadriven, performance-based decision-making on capital project selections?
  • Institutional Barriers to Reform. What organizational, legal, or procedural hurdles prevent DOTs and MPOs from adopting better practices (e.g., outcome-based planning, integrated land use/transportation policy)?
  • Permitting and Permit Reform. How do current local, state, and federal permitting practices affect project cost, quality, timeline, and other concerns?
  • Intergovernmental Dynamics. How do federal, state, and local funding structures and requirements enable or constrain effective transportation investment? What governance structures would improve outcomes when it comes to transportation planning and project delivery?
  • Data Sets and Root Causes of High Delivery Costs. Expanded data sets on unit costs and/or research illuminating the root causes of why transportation and transit projects cost so much and take so long to deliver. What policy and practice changes could manage project delivery risks and improve the likelihood that projects will be delivered on s chedule and on budget?
  • Domestic Content. How do Buy America and domestic content requirements affect the cost, speed, innovation, and effectiveness of transportation infrastructure projects?
  • Procurement Process. How do current procurement practices affect project cost, quality, innovation, and accountability — and what policy and regulatory reforms could improve outcomes?
  • Other. AV also welcomes innovative proposals on other transportation issues that align with our mission.

These research, policy development, and implementation proposals can be relevant to federal surface transportation reauthorization legislation or federal administrative changes; state reforms to Departments of Transportation; and/or local-level reforms relevant either to regional transportation agencies, transit agencies, or municipal governments.

Public Policy Public Transportation & Mass Transit Systems Public Infrastructure

Clinical Trials Addressing Unmet Needs of Rare Neurodegenerative Diseases (R01) Clinical Trials Required

US Department of Health & Human Services: Food and Drug Administration (FDA)
Federal Government
United States
US $650,000 - US $900,000
The US Department of Health & Human Services, through the FDA, is funding clinical trials targeting rare neurodegenerative diseases. This initiative aims to enhance treatment options by evaluating the efficacy and safety of new products for both children and adults. By fostering innovative and collaborative trial designs, the FDA seeks to accelerate the approval of new therapies, ultimately benefiting patients with rare conditions and advancing drug development in this critical area.
Pharmacology Drug Safety Neurological Diseases & Disorders +1 more

Breast Cancer Community Education Grants for ONS Chapters

Oncology Nursing Society
Private
United States
Up to US $1,000
The Breast Cancer Community Education Grants, funded by the Oncology Nursing Foundation through AstraZeneca HealthCare Foundation, aim to enhance breast cancer awareness through nurse-led community education programs. Grants of up to $1,000 are available to ONS Chapters in the U.S., enabling them to implement impactful educational initiatives. Eligible activities must focus on community outreach and education, fostering a broader understanding of breast cancer.
Nursing Breast Cancer Community Health Education

Martha Rodriguez Scholarship Fund

Nurses Educational Funds Inc.
Private
United States
Unspecified amount

Nurses Educational Funds

Nurses Educational Funds, Inc. depends solely on donations to advance our only mission, to promote nursing leadership through annual scholarship support for professional nurses seeking masters and doctoral degrees in nursing education, practice, research, and administration.

NEF’s only purpose is to provide nursing scholarship assistance to make graduate level nursing education possible. NEF is one of the largest, national, private, professionally endorsed source of funds for advanced nursing study with over one hundred years of service to and for professional nursing. NEF is a non-profit organization with 501(c) status.

Martha Rodriguez Scholarship Fund

Martha Rodriguez Memorial Scholarship was initiated in 2025 by Lisa Ackerman, close friend and then Director of the Columbus Citizens Foundation. Raised in Gary, Indiana and a true New Yorker, Martha died as the result of traumatic head injuries from a tragic accident just outside her NYC apartment. Martha Rodriguez gave in life, working as a nurse helping patients navigate the trauma of breast cancer at Memorial Sloan Kettering Cancer Center. In her death, she was lauded by the President of LiveOnNY, an organization that coordinates and oversees organ donations, for her last selfless act of giving. Martha donated organs that gave life and hope and helped three people lead better lives. Her zest for life was contagious, and her dedication, compassion, and expertise left an indelible mark on the lives of countless MSKCC patients and caregivers. She was a friend and mentor to many. She loved being a nurse at MSKCC and worked for more than 28 years as a nurse practitioner and for the last 15 years of her life dealing with breast cancer patients. This scholarship is awarded to nurses studying in master's or doctoral programs who are dedicated to oncology care, or women’s health, or are Latinx nurses.

Education - Higher Education Nursing Cancer / Oncology +1 more

The Jenna’s Rainbow Moving Forward Grant

Childrens Brain Tumor Foundation Inc.
Private
United States
Unspecified amount
The Jenna’s Rainbow Moving Forward Grant, offered by the Children’s Brain Tumor Foundation, provides crucial financial assistance to adult survivors of brain or spinal cord tumors. Aimed at fostering independence, this grant supports costs associated with job transitions, new living situations, and resources to enhance self-sufficiency. Eligible applicants must be at least 18 years old, diagnosed before 21, and not have received recent funding from CBTF or JRF. This initiative empowers survivors to overcome challenges and move forward in their lives.
Education - Higher Education Vocational & Trade Education Education - High School +2 more

The Amazing Grace Scholarship

Childrens Brain Tumor Foundation Inc.
Private
United States
US $1,000
The Amazing Grace Scholarship, established by the Children's Brain Tumor Foundation, honors Grace Fulcher, a brain tumor survivor. This scholarship supports students diagnosed with brain or spinal cord tumors before age 21, who reside in the U.S. and are pursuing higher education. With a $1000 award, the scholarship aims to empower survivors to achieve their educational goals, inspired by Grace's resilience and academic success despite her challenges.
Education - Higher Education Vocational & Trade Education Education - High School +2 more

Lakken’s Legacy Survivor Scholarship

Childrens Brain Tumor Foundation Inc.
Private
United States
US $1,000
The Lakken’s Legacy Survivor Scholarship, offered by the Children’s Brain Tumor Foundation, awards $1,000 to brain tumor survivors pursuing education beyond high school. This initiative honors Lakken, who faced challenges during her cancer journey yet remained passionate about education. The scholarship aims to support individuals diagnosed with brain or spinal cord tumors before age 21, ensuring they have the opportunity to continue their studies in various educational institutions. It's a commitment to empower survivors and foster their dreams.
Education - Higher Education Vocational & Trade Education Education - High School +2 more

Louis Stokes Alliances for Minority Participation (LSAMP) Bridge to Doctorate Scholars Program

Montana State University
State/Local Government
United States
US $88,000
The Louis Stokes Alliances for Minority Participation (LSAMP) Bridge to Doctorate Scholars Program, funded by the National Science Foundation, aims to recruit and retain minority graduate students in STEM fields. This program offers significant benefits, including a $32,000 annual stipend and $12,000 educational allowance for two years, fostering a supportive community through monthly dinners for Indigenous graduate students. Eligible applicants must be U.S. citizens, identify as American Indian or Alaska Native, and have participated in an LSAMP program.
Education - Higher Education Academic Success & Enrichment Academic Scholarship Programs +3 more

LinkScholars Program Scholarship

Central Carolina Community Foundation
Private
United States
Unspecified amount

About

Central Carolina Community Foundation is a nonprofit organization that helps generous people give back to the Midlands of South Carolina in ways that matter. Since 1984, we’ve been a trusted partner, helping individuals, families, and businesses make smart, meaningful contributions that support local nonprofits, scholarships, and community projects.

LinkScholars Program Scholarship ($2,000) 

This renewable scholarship supports graduating high school seniors from Fairfield, Kershaw, Lexington, Richland, or Sumter counties in South Carolina.

Education - Higher Education Vocational & Trade Education Education - High School +2 more

Lakken’s Legacy Sibling Scholarship

Childrens Brain Tumor Foundation Inc.
Private
United States
US $1,000
The Lakken’s Legacy Sibling Scholarship, established by the Children’s Brain Tumor Foundation, honors Lakken Burzynski's courage and resilience in her battle with cancer. This $1,000 scholarship is designed for siblings of children diagnosed with brain tumors, emphasizing support for families impacted by such challenges. Eligible applicants must be 21 or younger at diagnosis and reside in the U.S. This initiative promotes positivity and hope, continuing Lakken's legacy of strength and family support.
Education - Higher Education Vocational & Trade Education Education - High School +2 more

Joyce Price Johnson’s Samaritan Fund

North Carolina Community Foundation Inc
Private
United States
More than US $1,000
The Joyce Price Johnson’s Samaritan Fund provides scholarships for young people in North Carolina who are exiting foster care or facing poverty. Eligible candidates include undergraduates, graduates, and adult re-entry students attending various accredited institutions. Applications for NCCF scholarships open on December 16, 2025, and close on March 3, 2026. Preference is given to applicants from Wayne County and adjacent areas, ensuring support for those with exceptional financial need.
Education - Higher Education Education - High School Academic Scholarship Programs +2 more

Carson Bailey Memorial Scholarship for Siblings

Childrens Brain Tumor Foundation Inc.
Private
United States
US $1,000
The Carson Bailey Memorial Scholarship for Siblings, established by the Children’s Brain Tumor Foundation, honors the memory of Carson Bailey. This scholarship aims to support brain tumor survivors pursuing their educational goals. Eligible applicants must have been diagnosed with a brain or spinal cord tumor before age 21, reside in the U.S., maintain a GPA of 2.0 or higher, and be at least a senior in high school. A $1000 scholarship is available for those attending various educational institutions.
Education - Higher Education Vocational & Trade Education Education - High School +2 more

Carson Bailey Memorial Scholarship

Childrens Brain Tumor Foundation Inc.
Private
United States
US $1,000
The Carson Bailey Memorial Scholarship, established by the Children's Brain Tumor Foundation, honors the memory of Carson Bailey, a dedicated student and beloved family member. This scholarship is aimed at brain tumor survivors who have been diagnosed before the age of 21 and seek to pursue higher education. It provides $1000 to eligible applicants, supporting their educational aspirations while promoting inclusiveness and respect for all backgrounds within the brain tumor community.
Education - Higher Education Vocational & Trade Education Education - High School +2 more

Charles B. Decker Memorial Scholarship

Adirondack Foundation
Private
United States
Unspecified amount
The Charles B. Decker Memorial Scholarship, established in 1991, supports college and graduate students from the Tri-Lakes area pursuing journalism careers. This scholarship emphasizes the importance of education in the Adirondack region by providing essential financial assistance to students dedicated to journalism. Candidates are evaluated based on financial need, demonstrated commitment to journalism, and academic achievements, ensuring that the scholarship aligns with the foundation's mission to invest in educational opportunities.
Education - Higher Education Education - High School Academic Scholarship Programs +2 more

Grayce Wills MacDonald and Ivan A. MacDonald Endowment

North Carolina Community Foundation Inc
Private
United States
More than US $1,000

Scholarships

We partner with donors to administer scholarships for students across the state. Most NCCF scholarships open for applications on Dec. 16, 2025, and close on March 3, 2026.

Undergraduates, graduates, medical and professional school students and adult re-entry students who are attending community colleges, four-year universities, career/technical schools, teaching credential programs and graduate, medical or professional schools in the United States are eligible for scholarships offered at NCCF.

Each scholarship has specific eligibility requirements defined by the donor when the scholarship was established. Be sure to read the requirements of each scholarship carefully as directed through the universal application and address those elements as needed in your application.

Grayce Wills MacDonald and Ivan A. MacDonald Endowment

Shall support students who attended high school in Cherokee, Graham, Clay, Swain, Macon, Jackson, Haywood, Buncombe, and Henderson counties, and who are pursuing a college or post-graduate level degree in the field of nutrition with emphasis on the study of natural foods and the vegetarian lifestyle. Scholarships may be based on both need and merit.

Education - Higher Education Education - High School Academic Scholarship Programs +2 more

GLLCF Nursing Scholarship

Greater Lake City Community Foundation
Corporate
United States
Unspecified amount

About

Created by the community for the good of the community, the GLCCF is here to turn problems into opportunities through strategic grant making and initiatives created to address our region’s most pressing needs. We work with you to identify your charitable goals, and we ensure that they are carried out efficiently.

Work with us to make the kind of impact you want to see in your community. Let us take on the financial complexities and paperwork, while you focus on the important things like fostering good works throughout our community.

When you give to the Greater Lake City Community Foundation, you are making an investment that will benefit the community, now and in the future.

GLLCF Nursing Scholarship

To award annually a scholarship to a qualified applicant who intends to further his/her education toward a degree in nursing.

Education - Higher Education Education - High School Academic Scholarship Programs +2 more

Howe Foundation Grant

Howe Foundation 45871100
Private
United States
Approximately US $5,000
The Howe Foundation, established by Thomas E. Howe in Clark County, Nevada, supports U.S. charitable organizations focused on education, medical advancements, and game hunters associations. Grants are administered by Wells Fargo Bank, with applications reviewed annually in September. Eligible organizations must be 501(c)(3) exempt under the Internal Revenue Code, ensuring support for meaningful community initiatives.
Education Health & Medicine Wildlife Management +1 more

Edith M. Pritchard Scholarship

Nurses Educational Funds Inc.
Private
United States
Unspecified amount
The Edith M. Pritchard Scholarship, offered by Nurses Educational Funds Inc., supports nurses pursuing master's or doctoral degrees in nursing education and public health. Applicants must hold a current RN license, maintain a GPA of 3.6, and have at least two semesters of study remaining post-award notification. This scholarship promotes nursing leadership and is funded through donations, reflecting over a century of commitment to nursing education.
Education - Higher Education Nursing Mental Health & Psychiatric Diseases +2 more

Environmental Engineering and Science Foundation Master's Degree Scholarship Program

Environmental Engineering and Science Foundation (EESF)
Association/Society
United States
US $2,500
The Environmental Engineering and Science Foundation offers six Master's Degree scholarships of $2,500 each for students pursuing advanced studies in Environmental Engineering or related fields. Eligible candidates must be U.S. citizens or permanent residents, have a strong academic record with a minimum GPA of 3.0, and be accepted into an accredited graduate program. This initiative aims to support future leaders in environmental engineering and science.
Education - Higher Education Ecology Geology +4 more

Allison Adams Wieczorek Scholarship

Nurses Educational Funds Inc.
Private
United States
Unspecified amount
The Allison Adams Wieczorek Scholarship supports graduate nurses pursuing degrees in maternal-infant and pediatric nursing. Established through the Nurses Educational Funds, Inc., this scholarship honors the contributions of Allison Adams Wieczorek, a dedicated board member with extensive experience in financial services. Applicants must have at least two semesters of study remaining and meet specific eligibility criteria, including holding a current RN license and maintaining a minimum GPA of 3.6. This initiative fosters nursing leadership and education.
Education - Higher Education Nursing Mental Health & Psychiatric Diseases +2 more

Operating Grants for Nonprofits in North Carolina Highlights

Looking for operating grants for nonprofits in North Carolina?


Read more about each grant below or start your 14-day free trial to see all operating grants for nonprofits in North Carolina recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Operating Grants for Nonprofits in North Carolina

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Operating grants for nonprofits in North Carolina grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

70 Operating grants for nonprofits in North Carolina over $25K in average grant size

51 Operating grants for nonprofits in North Carolina over $50K in average grant size

35 Operating grants for nonprofits in North Carolina supporting general operating expenses

200+ Operating grants for nonprofits in North Carolina supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

2,000+ Grants on Instrumentl focused on Human & Social Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Operating grants for Nonprofits in North Carolina?

Most grants are due in the first quarter.

Q1
30.4%
Q2
22.4%
Q3
26.2%
Q4
21.1%

Typical Funding Amounts

What's the typical grant amount funded for Operating Grants for Nonprofits in North Carolina?

Grants are most commonly $17,500.

$500 $500 Min.
$17,500 $17.5 K Median
$477,452 $477.5 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for North Carolina?

Grants are most commonly $131,121.

$131,121

Total Number of Grants

What's the total number of grants in Operating Grants for Nonprofits in North Carolina year over year?

In 2024, funders in North Carolina awarded a total of 70,602 grants.

2022 63,850

2023 62,335

2024 70,602

Top Grant Focus Areas

Among all the Operating Grants for Nonprofits in North Carolina given out in North Carolina, the most popular focus areas that receive funding are Education, Human Services, and Philanthropy, Voluntarism & Grantmaking Foundations.

1. Education

2. Human Services

3. Philanthropy, Voluntarism & Grantmaking Foundations

Funding Over Time

How is funding for Operating Grants for Nonprofits in North Carolina changing over time?

Funding has increased by 15.49%.

2022 $7,927,620,616

2023 $7,987,830,464
0.76%

2024 $9,224,796,270
15.49%

North Carolina Counties That Receive the Most Funding

How does grant funding vary by county?

Durham County, Orange County, and Mecklenburg County receive the most funding.

County Total Grant Funding in 2024
Durham County $2,942,551,198
Orange County $2,549,339,233
Mecklenburg County $1,468,677,341
Wake County $1,122,908,782
Buncombe County $444,853,701

Related Grants in North Carolina

Browse Other Nonprofit Operations & Capacity Grants in North Carolina

Browse Grants For Nearby Locations

Browse Grants by Major US Cities within North Carolina