Best Small Grants for Nonprofits in North Carolina

The Conchologists of America (COA) offers grants up to $2,500 for research on recent or fossil mollusks. This funding is available for projects that explore malacological topics, ensuring that the proposed work is self-contained and capable of addressing specific research questions. While COA encourages applications for amounts less than the maximum, funding is not typically awarded to high school students or for institutional overhead. This initiative supports a wide range of malacological disciplines.

The Lung Cancer Discovery Award, offered by the American Lung Association, supports innovative research aimed at improving outcomes for lung cancer patients. With funding of $100,000 per year for up to two years, this award encourages groundbreaking projects that enhance diagnostic and therapeutic strategies, investigate genetic forms of lung cancer, and develop novel screening methods. The initiative is a vital step towards reducing lung cancer morbidity and mortality, ultimately improving patient care and saving lives.

The Walking College Fellowship, offered by America Walks, is an innovative online program aimed at empowering community champions to enhance walkability. Participants engage in six modules, committing 5-10 hours weekly, to develop actionable plans addressing local challenges. Over 200 alumni have successfully implemented initiatives such as sidewalk installations and complete streets policies. The program encourages diverse candidates, fostering collaboration and effective advocacy for safer, more accessible communities.

The Arthur F. Burns Fellowship offers journalists from the U.S., Canada, and Germany a unique opportunity to enhance their skills through a two-month exchange program. Participants engage in a structured orientation in Washington, D.C., followed by hands-on training at German media outlets. This fellowship not only enriches careers but also fosters international understanding, with many alumni advancing in prominent media roles globally. With financial support for living and travel expenses, this program significantly enhances the quality of transatlantic news coverage.

The AOTF Implementation Research Grant supports innovative research aimed at integrating evidence-based practices into occupational therapy. This grant encourages projects that directly involve stakeholders, particularly from underrepresented populations, to address health inequities. With funding options of up to $100,000 for two years or $50,000 for one year, the AOTF seeks to enhance the effectiveness of care through practical implementation strategies in diverse clinical settings.

The American Occupational Therapy Foundation's AOTF Intervention Research Grant Program supports innovative research in occupational therapy, providing up to $100,000 for projects that address health inequities and social justice. This initiative aims to generate preliminary data essential for larger studies, aligning with the profession's Vision 2025. By focusing on underrepresented populations, the program encourages inclusivity and ethical research practices, ensuring a diverse study population. This funding opportunity is crucial for advancing evidence-based practices in occupational therapy.

The Journalism & Media Grant aims to promote inclusive narratives and accurate media that engage communities in democratic processes. It supports U.S.-based nonprofit organizations focused on professional reporting, multimedia storytelling, and civic media. The grant addresses barriers to media participation and fosters innovation in journalism, providing essential infrastructure for a diverse media landscape. While unsolicited proposals are not accepted, organizations can share ideas through a Letter of Inquiry (LOI).

The Edna B. Collins Scholarship, offered by the Community Foundation of Central Wisconsin, supports graduating seniors from Wautoma pursuing a degree in business. With awards ranging from $500 to $40,000, this scholarship aims to help students achieve their educational goals. Selection is based on academic performance, financial need, and extracurricular involvement, encouraging a diverse range of applicants to apply for this valuable opportunity.

The American Journalism Project is dedicated to enhancing local news organizations by investing in their business capacities and providing personalized coaching. They prioritize diversity, equity, and inclusion, encouraging inquiries from organizations serving underrepresented communities. Their approach offers tailored support based on grantees' strategic challenges, fostering sustainable growth in revenue and programming. They seek grantees with strong public-service missions, independent 501(c)(3) status, and a commitment to transparency and accountability in their operations.

The Collaborative Centers in Children’s Environmental Health Research and Translation program aims to establish a national network of research centers focused on improving children's health through innovative research and public health strategies. By fostering collaboration within the children’s environmental health community, these centers will lead the way in translating scientific findings into actionable practices, ensuring a healthier future for children while addressing emerging environmental threats.

The OAR Community Grant aims to enhance the quality of life for autistic individuals by funding community-led projects that address physical health and support services. Grants ranging from $1,000 to $15,000 are available for initiatives designed to produce practical tools and resources. Eligible applicants include family members, autistic individuals, and community organizations committed to improving the lives of those affected by autism. Projects should be innovative, publicly accessible, and focus on priority topics such as health systems and community services.

The OJJDP FY 2026 Second Chance Act Youth Reentry Program aims to provide critical support for moderate- to high-risk youth transitioning back into their communities after confinement. This funding opportunity encourages collaboration among state agencies, local governments, Tribes, and community organizations to deliver comprehensive reentry services and assist youth in overcoming challenges related to recidivism. Applications are due by November 9, 2026, at 8:59 p.m. ET.

The OJJDP FY 2026 Internet Crimes Against Children (ICAC) Task Force Program Support aims to fortify a national network of 61 multiagency task forces dedicated to combating child sexual exploitation facilitated by technology. This funding opportunity enhances training, prevention, and outreach efforts while fostering collaboration among law enforcement entities. Applications are due in JustGrants by November 9, 2026, at 8:59 p.m. ET, ensuring timely support for critical initiatives to protect children.

The Gender Justice Organizing Fund Grant supports initiatives led by women, girls, trans, gender nonconforming, and LGBTQI+ individuals to achieve gender justice. Organizations must prioritize community organizing and demonstrate an understanding of systemic oppression. Grants from the Bread & Roses Community Fund are crucial for groups that lack traditional funding due to their commitment to amplifying marginalized voices. The fund emphasizes long-term strategies that foster sustainable social change in the Philadelphia area.

The American Epilepsy Society offers Postdoctoral Research Fellowships to support trainees conducting research on epilepsy's causes, treatment, and consequences. These fellowships provide up to $49,000 for stipend and benefits, $1,000 for travel to the AES annual meeting, and complimentary membership. Proposals can be basic, translational, or clinical research, and the number of awards depends on available funding.

The Advanced Rehabilitation Research Training (ARRT) Program, funded by the US HHS: Administration for Community Living, aims to enhance the capabilities of individuals with advanced degrees in conducting high-quality research focused on health and function outcomes for people with disabilities. The program offers advanced training opportunities over a 36-month period, specifically targeting rehabilitation researchers, including those with disabilities, to foster multidisciplinary approaches in disability and rehabilitation research.

The American Epilepsy Society offers Predoctoral Research Fellowships to support students conducting epilepsy-related dissertation research under expert mentorship. Proposals in basic, translational, or clinical research are encouraged. Each fellowship provides up to $30,000 for stipend and travel to the AES Annual Meeting for one year, along with a one-year AES membership. The number of awards varies annually based on available funding.

The Field Initiated Projects Program aims to foster new research and develop solutions that enhance the inclusion and independence of individuals with disabilities. This initiative focuses on generating scientific knowledge and understanding critical issues faced by these populations, particularly those with significant support needs. With a total of 16 grants available over a 36-month period, this program encourages innovative approaches that support employment, living arrangements, and caregiver involvement.

LSC’s Basic Field Grants aim to enhance access to civil legal services for low-income individuals across the U.S. and territories. These grants support eligible organizations for up to three years through a competitive application process. The funding is allocated to specific service areas, which change annually, and focuses on providing comprehensive legal assistance. The program includes three types of service areas, ensuring diverse populations, including agricultural and Native American communities, receive necessary legal support.

The Anderson Foundation for Autism Grant supports organizations aiming to enhance the quality of life for individuals with autism. Grants of up to $50,000 are available for qualified 501(c)(3) organizations, enabling them to implement impactful programs. The foundation not only funds its own initiatives but also extends support to other entities dedicated to similar goals. This initiative emphasizes a collaborative approach to improving autism care and support.

The Arthritis National Research Foundation (ANRF) offers grants for research focused on Psoriatic Arthritis (PsA). With funding of up to $125,000 over two years, the ANRF encourages innovative projects that reveal the underlying mechanisms of PsA. Eligibility includes M.D. or Ph.D. qualifications and affiliation with a U.S. nonprofit research institution. Preference is given to senior post-doctoral researchers transitioning to independent status and new assistant professors. Applications without a Co-PI or those who have previously received ANRF funding will not be accepted.

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is extending the Kidney Precision Medicine Project (KPMP) for five years to enhance participant recruitment and tissue interrogation. This initiative aims to discover novel molecular pathways associated with Chronic Kidney Diseases (CKDs) and Acute Kidney Injuries (AKIs). The renewed funding will support robust longitudinal follow-ups for existing enrollees and facilitate the enrollment of new participants, ensuring comprehensive data analysis and collaboration within the research community.

The Kidney Precision Medicine Project Central Hub, funded by the National Institute of Diabetes and Digestive and Kidney Disease (NIDDK), aims to enhance our understanding of Chronic Kidney Diseases (CKDs) and Acute Kidney Injuries (AKIs). This initiative, which began in FY2017, focuses on ethically collecting and analyzing kidney biopsy tissues to uncover molecular pathways. The project was expanded in FY2022 to improve participant recruitment and tissue analysis, driving forward research in kidney health.

The Frederic C. Collin Trust Grant supports 501(c)(3) organizations in promoting polo and tennis, especially among youth. Established under Frederic C. Collin's will, it offers grants ranging from $2,000 to $3,800, with an annual total giving of approximately $9,000. Applications are accepted year-round for consideration during the annual grant meeting. This initiative aims to enhance participation in these sports, fostering talent and interest among young players.

The National Fish Passage Program (NFPP) offers technical and financial support to restore aquatic connectivity for fish and other organisms. By improving infrastructure like culverts and bridges, the program enhances fish populations and ecosystem resilience, providing quality fishing experiences. Managed by the US Fish and Wildlife Service, NFPP collaborates with partners to implement strategic projects that align with conservation goals, ensuring biological diversity and effective use of scientific principles in project planning.

The Anna Fuller Fund Grant provides year-round support for organizations dedicated to alleviating suffering caused by cancer. Established in memory of Egbert C. Fuller’s wife, the fund prioritizes applications that focus on cancer research and education initiatives. Eligible applicants must be 501(c)(3) organizations or equivalent charities outside the U.S. Grant funds cannot be used for direct treatment, ensuring that resources are allocated to research and public education.

The Changing Aging (CA) Grant supports innovative projects aimed at enhancing economic opportunities for older adults and combating ageism. Priorities include advancing digital equity and promoting aging in place for marginalized communities. Funded by Next50, the grant encourages collaboration among nonprofits and requires an equity-focused approach to project design. Organizations may apply for up to three years of funding, with no maximum request limit, although a pre-application call is necessary for larger requests.