Best Small Grants for Nonprofits in North Carolina

The Plus Collective offers up to $25,000 in Programs, Projects, and Events (PPE) Grants to organizations serving the LGBTQ+ community in Charlotte. Grants aim to promote inclusion, leadership, and engagement among diverse populations. Eligible 501(c)(3) nonprofits can apply for direct grants of up to $5,000 or $7,500 when partnering with other organizations. The initiative prioritizes impactful projects that align with TPC's vision of community support and diversity.

The Kellly Marie Mcquate Memorial Scholarship, offered by the Quad Cities Community Foundation, supports graduating high school seniors from Rock Island or Scott County, IL, who have lost a parent. This need-based scholarship awards up to $500 and focuses on financial need as the primary criterion. Applicants must plan to enroll full-time in college, with merit evaluated through school and community activities. This scholarship represents a significant opportunity for eligible students to pursue their educational goals.

The Deana and Paul Strunk Military Veterans Scholarship Program offers financial aid ranging from $2,500 to $5,000 for veterans and military dependents pursuing geoscience degrees at accredited institutions. This program facilitates educational opportunities and aids in the transition of veterans to civilian careers. Eligible applicants must provide proof of military service and demonstrate financial need, along with academic excellence and a commitment to geoscience. This initiative aims to support both active service members and veterans in their educational journeys.

The VFW Student Fellowship, hosted by the Veterans of Foreign Wars and Student Veterans of America, empowers student veterans to advocate for their community on Capitol Hill. Running from October 2025 to March 2026, this program offers selected fellows the chance to collaborate on policy priorities, attend leadership training, and participate in significant conferences, ensuring their voices are heard among 500 advocates at the VFW Washington Conference. Travel expenses are fully covered.

The Dupuytren’s Disease Fund, managed by the HealthWell Foundation, aims to reduce financial barriers for underinsured patients suffering from Dupuytren's Disease. This fund provides assistance for prescription drug copays and insurance premiums related to treatment. With an average grant utilization of $1,650 over a 12-month period, the fund ensures that essential medications and therapies are affordable. HealthWell Foundation, a private non-profit, has helped over 1.1 million patients since 2004, demonstrating its commitment to healthcare access.

The Cushing's Disease or Cushing's Syndrome Fund, operated by the HealthWell Foundation, provides vital financial assistance to underinsured patients facing high medical costs associated with these conditions. The fund covers co-payments, insurance premiums, and necessary treatments, ensuring that patients receive the care they need without financial burden. With an average grant utilization of $3,000 over twelve months, this fund aims to alleviate the challenges of treatment accessibility, supporting both physical and mental health for those affected.

The ASH Graduate Hematology Award supports graduate students in the U.S. and Canada pursuing research in hematology. Offering a $40,000 annual stipend for two years, it covers tuition, research expenses, and travel to the ASH Annual Meeting. Eligible applicants must be PhD students in their first three years and have a mentor's support. This award aims to foster careers in academic hematology, encouraging innovative research in various hematologic fields.

The Blepharitis Fund, managed by the HealthWell Foundation, aims to alleviate financial barriers for underinsured patients suffering from blepharitis, an inflammatory condition of the eyelids. This program assists with prescription drug copays and insurance premiums, covering up to $3,500 annually for treatments. With a mission to ensure no patient is deprived of necessary healthcare due to financial constraints, the HealthWell Foundation has provided over $1.2 billion in grants, supporting more than 1.1 million patients since its inception.

The Amyotrophic Lateral Sclerosis Fund, managed by HealthWell Foundation, aims to alleviate financial barriers for underinsured patients battling ALS, a progressive neurodegenerative disease. The fund provides financial assistance for prescription copays, insurance premiums, and related healthcare expenses, ensuring patients can access vital treatments. With an average grant utilization of $3,000 over twelve months, the fund exemplifies HealthWell's commitment to ensuring no patient is denied necessary healthcare due to cost. Since 2004, HealthWell has awarded over $1.2 billion in grants, supporting more than 1.1 million patients.

The Alagille Syndrome Vitamins and Supplements Fund, managed by the HealthWell Foundation, offers financial assistance to patients suffering from Alagille Syndrome. This fund helps cover the costs of essential vitamins and supplements needed for treatment. With a maximum award of $1,500, the program aims to reduce financial barriers for underinsured individuals, ensuring they receive the necessary support to manage their health, thereby enhancing their quality of life.

The National Human Genome Research Institute (NHGRI) is set to release a Notice of Funding Opportunity (NOFO) focused on the ethical, legal, and social implications (ELSI) of genomics. This initiative aims to explore how genomics can enhance health and well-being while addressing its broader societal impacts. The NHGRI encourages applications from diverse academic disciplines to promote innovative and replicable research approaches that effectively analyze the consequences of genomic advancements.

The OREF/John W. Brown Early-Stage Investigator Grant supports innovative research in musculoskeletal health, encouraging early-stage investigators to submit proposals utilizing enabling technologies. Established by the Orthopaedic Research and Education Foundation, this grant honors John W. Brown's contributions to orthopaedics. With a maximum funding of $100,000 over one or two years, the grant aims to enhance clinical practice and improve patient outcomes through groundbreaking research.

The It Gets Better Project is offering 50 grants of up to $10,000 each to public and charter schools across the U.S. to enhance inclusivity for LGBTQ+ youth. Schools can propose projects such as enhancing library resources, artistic installations, or establishing support groups. The initiative aims to empower LGBTQ+ students and foster a supportive environment, ensuring that every school can participate in uplifting their communities and promoting equality.

The Barbara Hodgdon Award, presented by the Shakespeare Association of America (SAA), honors exceptional scholarship in the field of Shakespeare and Performance. Established in memory of Barbara Hodgdon, this award encourages innovative research across various media and time periods related to Shakespeare's work. Eligible submissions must be authored by SAA members and published two years prior to the award presentation. This recognition promotes new discussions and insights within the realm of Shakespearean performance studies.

Stark Community FoundationStark Community Foundation is one of the area’s major sources of college scholarship support— thanks to the generosity of caring individuals, families and businesses that have created scholarship funds. The Foundation currently manages more than 100 scholarship funds that support hundreds of deserving students each year from Stark and Carroll counties. In 2025, more than $1,000,000 was awarded to local students to help them achieve their educational dreams.The Canton Professional Educators' Scholarships FundThe Canton Professional Educators’ Scholarships Fund was established to assist high school graduates enrolled in an academic plan (college/university, 2-year vocational, technical or advanced study). Applicants must be the natural or adopted child of a CPEA member, must have achieved a cumulative high school GPA of 3.0 or above, and college students must be “a student in good standing.”Renewable scholarship: No

Stark Community FoundationStark Community Foundation is one of the area’s major sources of college scholarship support— thanks to the generosity of caring individuals, families and businesses that have created scholarship funds.

The Foundation currently manages more than 100 scholarship funds that support hundreds of deserving students each year from Stark and Carroll counties. In 2025, more than $1,000,000 was awarded to local students to help them achieve their educational dreams.The Canton Advertising Federation Endowment for Creative Enrichment FundThe Canton Advertising Federation Endowment for Creative Enrichment Fund assists graduating high school seniors or current college students majoring in advertising, graphic design, communication or related fields. Applicants must reside in Stark County.Renewable Scholarship: Yes

Stark Community FoundationStark Community Foundation is one of the area’s major sources of college scholarship support— thanks to the generosity of caring individuals, families and businesses that have created scholarship funds.The Foundation currently manages more than 100 scholarship funds that support hundreds of deserving students each year from Stark and Carroll counties. In 2025, more than $1,000,000 was awarded to local students to help them achieve their educational dreams.Adrienne O’Neill Scholarship FundThe Adrienne O’Neill Scholarship Fund was established to assist students who are the first generation in their family to attend college. Applicant must have a cumulative GPA of 2.5, demonstrate financial need and intend to utilize this scholarship as the “last dollars” after all aid/scholarships have been awarded.Renewable Scholarship: Yes

The AHRQ Small Research Projects (R03) program supports short-term research endeavors in primary care, enabling innovative pilot studies, secondary data analysis, and the development of research methodologies. This initiative encourages researchers to explore new technologies and approaches within limited resource frameworks, fostering advancements in healthcare quality and efficiency. Applications are due by 5:00 PM local time of the applicant organization, emphasizing the importance of timely submission.

The National Human Genome Research Institute (NHGRI) is launching a funding opportunity for the ancient DNA for Modern Genomics (aDMG) program. This initiative aims to create an ethical resource of ancient human DNA to enhance understanding of modern human traits and health. By leveraging both existing and new aDNA data, the program seeks innovative collaborations that integrate ancient and contemporary genomic information. Researchers with expertise in population genomics are encouraged to apply.

The George S. Souten Performing Arts Scholarship, offered by the Four County Community Foundation, supports high school seniors from Armada, Capac, Imlay City, and Romeo who plan to major or minor in performing arts. Applicants must demonstrate a strong background in the arts and submit an essay. Awardees will be recognized during the Foundation's Scholarship Celebration in May and at their respective high school awards events.

The Pichichero Family Foundation Research Development Award supports innovative research in pediatric infectious diseases, focusing on vaccine development and pathogenesis. Established in 2016, it encourages both new and established investigators to apply for grants of one to two years. Eligible applicants must be members of the Pediatric Infectious Diseases Society (PIDS) and should aim to create novel insights into vaccine and therapeutic advancements, avoiding overlap with existing funding sources.

The John R. Kiley Memorial Scholarship, offered by the Quad Cities Community Foundation, provides need-based financial assistance of up to $1,500 for students pursuing a Bachelor's Degree. Applicants must have a GPA of at least 3.25 and be enrolled or planning to enroll in college. Iowa residents can attend any institution, while Illinois residents may attend colleges in Iowa only. This scholarship emphasizes financial need, leadership, and academic merit.

The Jane & Clem Werner Scholarship, funded by the Quad Cities Community Foundation, awards $5,000 annually to five deserving seniors from specific local high schools. It is aimed at students with financial need who have a minimum GPA of 3.0 or are in the top third of their class, and who plan to enroll full-time in a college program. Preference is given to those attending private liberal arts schools outside a 150-mile radius of Arsenal Island.

The James W. Victor Scholarship, administered by the Quad Cities Community Foundation, offers up to $10,000 annually to graduating seniors from Davenport, Iowa, who demonstrate financial need and academic ability. This renewable scholarship can be maintained for up to four years, provided recipients uphold a minimum GPA of 2.5. With nearly $600,000 awarded yearly, it aims to support students pursuing higher education at various institutions.

The Horsley Opportunity Scholarship Fund, administered by the Quad Cities Community Foundation, provides need-based scholarships of up to $1,000 for Scott County, Iowa high school graduates. With a GPA requirement between 2.0 and 3.5, the scholarship especially encourages applications from nontraditional students and veterans. This initiative supports students in pursuing post-secondary education at community colleges, trade schools, or four-year institutions, contributing to over $600,000 awarded annually in scholarships.

The Dr. & Mrs. Yang Ho Rhee Scholarship, established in 2000, aims to support students of Korean heritage in the Quad Cities region. This scholarship provides up to $2,500 to graduating seniors who demonstrate financial need and have a minimum GPA of 3.0. It honors the Rhee family's commitment to education, ensuring that opportunities are available for local students to pursue higher education and achieve their academic goals.

The Corky Kress Golf Scholarship, administered by the Quad Cities Community Foundation, supports graduating seniors from specific high schools in Iowa who are members of their golf teams. This scholarship, which is need-based and offers up to $2,500, aims to assist students in covering college costs for two-year or four-year programs. Financial need is a primary criterion for selection, emphasizing the importance of academic performance and commitment to the sport.