Best Unrestricted Grants for Nonprofits in North Carolina

The FY26 Arthritis Research Program Clinical Research Award supports innovative clinical research addressing factors and interventions for arthritis. This program encourages proposals focusing on Prevention and Early Diagnosis or Treatment and Mitigation of Disease Progression. Applicants can choose between two research levels, with the requirement of a community collaborator for Research Level 2. Projects should aim to provide actionable evidence to enhance patient care and outcomes, making significant contributions to the field of arthritis research.

The DoW Arthritis Translational Research Award, funded by the U.S. Army Medical Command, aims to support high-impact translational research focused on accelerating findings into clinically relevant solutions for arthritis. This award is intended for preclinical or animal research, emphasizing the significance of the proposed outcomes in advancing arthritis research and benefiting Service Members, Veterans, and their Families. Applications must include preliminary or published data to demonstrate the feasibility and relevance of the research.

The ASF Family Fund Grant, offered by the Angelman Syndrome Foundation, provides crucial financial assistance to families of individuals with Angelman syndrome. This rare neuro-genetic disorder affects approximately 500,000 people globally. The fund aims to enhance the quality of life for affected individuals, allowing caregivers to apply for up to $5,000 to cover essential needs. Limitations include restrictions on certain expenses and prior grant awards. This initiative aims to support families through education and necessary resources.

The CFF/NIH R01-Unfunded Award, offered by the Cystic Fibrosis Foundation, supports exceptional CF-related research projects that have been submitted to NIH but lack funding. This program aims to bridge the gap for meritorious projects, providing up to $125,000 per year for two years. By facilitating research in cystic fibrosis, the foundation helps ensure that innovative ideas can continue to progress toward improving care and outcomes for individuals affected by this disease.

The CF Foundation/NIH K-Unfunded Award aims to support exceptional research projects in cystic fibrosis (CF) that have been approved by the NIH but lack funding. This award provides temporary financial assistance of up to $80,000 per year for two years to ensure that promising CF research continues without interruption. The initiative focuses on fostering a new generation of researchers dedicated to advancing CF studies while encouraging the NIH to provide long-term support.

The SETAC North America Student Meeting Attendance Grant supports student participation in annual meetings, emphasizing inclusivity and excellence. This program provides waived registration and stipends for costs such as travel and dependent care. Eligible students can apply during abstract submission from March to May, with grants available for each degree program. The initiative encourages applicants from diverse backgrounds, particularly those from indigenous communities and minority-serving institutions, enhancing representation within the environmental sciences.

Armstrong County Community Foundation

The Armstrong County Community Foundation, a public nonprofit corporation,

• Gives grants, scholarships, and organizational support to address the needs of our community.
• Builds a permanent endowment to help our donors create a legacy through this endowment.
• Promotes informed philanthropy to increase and sustain charitable resources for the region.
• Provides leadership and builds partnerships to identify and solve community issues.

Joan Tatsak Memorial Scholarship

Joan Tatsak was a beloved friend, colleague and mentor to many of our friends and neighbors here in Armstrong County. She inspired and encouraged her peers and coworkers to achieve and strive for excellence. This unique fund is a fitting memorial. The Joan Tatsak Memorial Fund is a non-traditional scholarship fund that offers grants for entrepreneurship, leadership and scholarship.

Scholarship Details

• Available to Adult Students
• Nonrenewable

All ACCF Scholarships are merit based.

$20K for changemakers with transformative ideas & firsthand insight in early childhood

About the Imagine Award

The Imagine Award by the Promise Fund offers $20,000 in flexible funding (see definition in FAQs) and a six-month cohort-based learning experience for community-rooted early childhood leaders with ideas for transformative impact. ​​Award recipients are at the idea stage and will launch a pilot within six months, testing their solutions with real users, gathering feedback, and refining their approach.

Imagine Award recipients will learn strategies for designing and executing lightweight tests for rapid learning while gaining clarity on their idea's direction using impact and business models. They will craft a compelling story about their work to build future partnerships and run a focused pilot with strong feedback loops for gathering data, all while growing alongside a supportive peer community.

What We Provide

Our grant dollars are flexible and meant to be used at award recipients’ discretion for the pursuit of tests or a pilot of a transformative idea. Read the FAQ for more information.

Direct, one-on-one support from our team to help you learn, get tailored help, and make relevant connections.

Multi-day gathering for peer connection, learning, and pilot design.

Access to a bench of mentors to guide you as you transition out of the program and navigate next steps with your pilot.

Light, tailored coaching to support pilot preparation, launch, and implementation.

Ongoing peer community and resources to continue learning and collaboration

The Cystic Fibrosis Foundation's Student Traineeship Award supports students in engaging with cystic fibrosis research through hands-on projects. With a maximum funding of $4,000 for one year, the program aims to inspire students to pursue careers in CF research or care. Eligible applicants must be enrolled in a degree program and collaborate with a faculty mentor on a relevant project. This initiative also emphasizes the importance of maintaining interest in CF-related research among new generations.

The Cystic Fibrosis Foundation offers a Travel Award Supplement aimed at supporting Ph.D. students, postdoctoral fellows, and junior faculty. This funding of up to $3,000 enables trainees to participate in off-site workshops or training programs to enhance their research skills. Eligible applicants must be active researchers in CF projects, with a minimum of one year of experience. The program excludes conference attendance and for-profit entities, ensuring focused support for advancing cystic fibrosis research.

The Harry Shwachman Clinical Investigator Award, offered by the Cystic Fibrosis Foundation, supports clinically trained physicians transitioning to independent researchers in cystic fibrosis. It provides up to $133,000 per year for three years to facilitate research tailored to individual interests. The funding covers personnel costs and supplies, promoting a strong mentorship during this critical stage of their academic careers.

The Path to a Cure (PTAC) - Postdoc-to-Faculty Transition Award by the Cystic Fibrosis Foundation supports postdoctoral fellows in advancing their research careers in cystic fibrosis. This program offers up to five years of funding, including 3 years for research training and 2 years for transitioning to an independent faculty position, with a maximum support of $110,000 per year. It aims to foster innovative research that develops new therapies for cystic fibrosis.

Margaret B. Moeller Memorial Fund for Alzheimer's Home Care Companions

Grants support families in the Boyertown Area School District with members who suffer from Alzheimer's disease or other types of dementia.

The Margaret B. Moeller Fund for Alzheimer's Home Care Companions provides grants for families in the Boyertown Area School District with individuals who suffer from Alzheimer's disease or other types of dementia to obtain the services of in-home care companions, aides or other providers of respite care. Grants generally pay for several days of care for a specified period of time. The fund was created to help families who are not eligible for any other form of reimbursement for such services. Decisions are generally made within 15 days of receiving a complete application, including the referral.

The Cystic Fibrosis Foundation offers the Path to a Cure (PTAC) Postdoctoral Research Fellowship Award to support innovative research training in cystic fibrosis (CF). Aimed at enhancing scientific knowledge and facilitating the transition to independent careers, this program funds projects targeting the development of new therapies for CFTR variants. Awards can reach up to $75,000 in the first year and $76,000 in the second year, fostering foundational research that could lead to breakthroughs in CF treatment.

The APSF/FAER Mentored Research Training Grant aims to enhance anesthesia patient safety by funding promising anesthesiologists who are within 10 years of their first faculty appointment. This two-year grant, totaling $300,000, supports the development of independent researchers focused on perioperative safety. Recipients must allocate 60% of their time to research and career development. With this initiative, the APSF and FAER seek to cultivate the next generation of safety scientists in anesthesia.

The Pizza Hut Foundation is offering scholarships for students demonstrating financial need and community leadership. Eligible applicants must be U.S. residents aged 17-26, enrolled in accredited post-secondary education for Spring 2026, and maintain a minimum GPA of 2.5. Scholarship amounts range from $500 to $5,000, with distribution to be made in Spring 2026. The application period runs from July 8 to September 5, 2025, with notifications for recipients by November 17, 2025.

The National Swine Resource and Research Center (NSRRC) is a pivotal resource that enhances biomedical research by providing genetically modified models. This centralized facility reduces variability and costs for researchers, allowing them to focus on scientific discovery. NSRRC offers breeding, cryopreservation, and genotyping services, ensuring consistent access to high-quality models. By consolidating these resources, it promotes reproducibility and supports the development of innovative methodologies in research, ultimately advancing our understanding of human health and disease.

The James S.T. Yao Resident Research Award encourages early-career physicians in the U.S. and Canada to engage in groundbreaking research on vascular diseases and therapies. Awarded by the SVS Basic and Translational Research Committee, it includes a $5,000 prize, a presentation opportunity at the Vascular Annual Meeting, and a subscription to the Journal of Vascular Surgery. This award honors the legacy of Dr. James S.T. Yao, a prominent figure in vascular research.

The Grant for Grassroots Exchange: U.S.-Japan Community Networking supports initiatives that foster connections between grassroots communities in the U.S. and Japan. With funding up to $10,000, projects should enhance mutual understanding through events like workshops and conferences. Eligibility is limited to U.S. organizations with 501(c)(3) status, and priority is given to collaborations with underrepresented groups. This grant aims to strengthen community ties and promote cultural exchange on a local level.

Mission & Vision

Rochester Area Community Foundation, in partnership with generous philanthropists and community partners, works to improve the quality of life for people who live and work in the eight-county region through its leadership and strategic grantmaking.

Our Mission:

We are cultivating a thriving Greater Rochester region — powered by philanthropy, grounded in community, and sustained across generations.

Our Vision:

We envision a Greater Rochester region transformed by enduring philanthropy, where every person, neighborhood, and future generation can thrive.

Joseph and Lorraine Finley Scholarship

Purpose of Scholarship

To provide financial support to high school seniors who are residents of the Wayne County town of Walworth and continuing their education at any accredited two-year, four-year, or technical school.

Number and Size of Awards

Four awards of $7,000 each; paid as $1,750 per year for up to four consecutive years of undergraduate study. Award paid in the Fall and divided equally between the Fall and Spring semesters.

Donor Information

This scholarship was established by a couple who believed in education and in helping their community.

Who We Are

Saginaw County is home. It is a beautiful community you’d be foolish to underestimate. We may have our challenges, but seeing its cities, villages and townships continue to grow and flourish gives us a sense of satisfaction and pride like none other.

Back in 1984, The Saginaw Community Foundation was founded to enhance the quality of life in our county by providing leadership, education, and support for philanthropy. Today, we still continue this mission of supporting the needs of our community through targeted grants, investments, and scholarships.

In addition to our grantmaking and scholarship programs, the Foundation also offers donor advised funds, which allow donors to recommend charitable grants to organizations of their choice. We also manage several endowed funds, which provide ongoing support for specific causes or organizations.

Saginaw Community Foundation is governed by a Board of Directors composed of community leaders and volunteers. A staff of professionals oversee our day-to-day operations and work with donors and community organizations to identify and address community needs.

CTE Scholarships

Dreaming of a career in welding? Maybe managing your own auto mechanics garage fuels your thoughts or you would love to become an electrician. Perhaps studying to become a chef in a culinary arts program suits your tastes.

No matter what your career path may be, there is little doubt that in recent years interest in Career and Technical Education (CTE) has grown. The increased need for workers skilled in the trades has resulted in larger numbers of students seeking out CTE programs.

Schools offering CTE encompass a wide variety of hands-on education, from HVAC to carpentry to cosmetology. In the past, financial assistance has been hard to come by for these areas of study, but that is no longer the case. Saginaw Community Foundation has several scholarship opportunities for those who have the desire to pursue CTE.

According to leading economists, not everyone needs a four-year degree. In fact, millions of good-paying jobs are opening up in the trades. And some pay better than what the average college graduate makes.

For aspiring welders, electricians, carpenters, and other valued skilled trade workers, there is great opportunity to take advantage of tailored CTE programs. The demand is massive as an estimated 3 million trade jobs in the United States remain vacant.

Our CTE scholarship awards range between $500 – $4,000 typically.

Reverend William D. Aldridge, Sr., Scholarship

The Reverend William Desmond Aldridge, the second oldest of five children, was born May 1, 1927, in Europa, Miss. The Reverend Aldridge was called to the ministry in 1944 at the age of 17. He completed three years of study at Rusk College before accepting his first pastorship in 1948. The Reverend Aldridge was named pastor of Christ Community Church on Easter Sunday in 1954, making him one of the longest-serving pastors in Saginaw County.

The Reverend Aldridge taught in the Buena Vista School District for nearly 10 years and has always placed a high priority on encouraging youth to seek academic excellence. Mary Viola “Jean” Aldridge, his wife of 50 years, was a teacher in the Buena Vista School District as well.

The Reverend Aldridge also worked at the General Motors Malleable Iron Plant and retired in 1981 after 28 years of service.

The Rev. Dr. Roosevelt and Dr. Nurame Austin, Sr. Scholarship, established by the Saginaw Community Foundation, honors Pastor Roosevelt Austin's dedication to his church and community. This scholarship supports graduating high school seniors from Saginaw County pursuing undergraduate degrees or Career and Technical Education (CTE) training. With awards ranging from $500 to $4,000, it fosters educational opportunities for students in skilled trades, reflecting Pastor Austin's belief in the power of education.

The OJJDP FY 2026 Community and Schools Youth Drug Prevention Program aims to combat youth substance use through comprehensive prevention strategies. This initiative invites applications from states, local governments, and nonprofit organizations to develop programs that educate and support youth in schools and community settings. By fostering collaboration with law enforcement and community coalitions, the program seeks to build capacity and implement effective interventions to protect the well-being of American youth.

The AMD Resident Research Grant aims to foster innovative research projects related to migraine, encouraging residents to explore diverse topics that are scientifically sound. Applicants, who must be enrolled in accredited training programs, can collaborate with preceptor investigators and receive support from their institutions. The grant is open to all residents without country restrictions, promoting advancements in migraine understanding and treatment.

The St. Baldrick’s Foundation Fellowship Award supports pediatric oncology training through a two-year fellowship, with a potential third year based on need and achievements. This initiative, powered by community fundraising events, aims to advance research for childhood cancer cures. The award provides a salary capped at $97,500 per year, covering salary and benefits for fellows. This fellowship not only fosters professional growth but also contributes significantly to the fight against childhood cancers.

The St. Baldrick’s Foundation Research Grant Award supports innovative research aimed at curing childhood cancers. With funding of $100,000 per year for two years, this grant is designed for hypothesis-driven projects that can be laboratory, clinical, or epidemiological in nature. Established through community-driven fundraising events, the foundation empowers volunteers and donors to make a significant impact in the fight against cancer, ensuring a brighter future for young survivors.

The Raymond and Mary Jane Barry Educational Scholarship Fund, established by the Saginaw Community Foundation, aims to support students from Saginaw County pursuing careers in technical fields. With awards ranging from $500 to $4,000, this fund honors the Barrys' commitment to education and community service. Eligible applicants must maintain a minimum 2.7 GPA and demonstrate enrollment in a Career and Technical Education program or an undergraduate degree. This scholarship encourages students to overcome challenges with humor and determination.