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Best Unrestricted Grants for Nonprofits in North Carolina

Find the perfect Unrestricted grants for nonprofits in North Carolina on Instrumentl. 10,000+ Unrestricted grants for nonprofits in North Carolina in the United States.

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$2.70B

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$5K

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10,000+ grants
$2.70B total
$5K median

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DoW Breast Cancer, Clinical Research Extension Award (363671)

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The FY26 Breast Cancer Research Program's Clinical Research Extension Award aims to enhance breast cancer clinical studies by extending data collection and follow-up. This funding mechanism emphasizes the importance of patient participation and addresses challenges from early trial terminations. Notably, applications must include two breast cancer consumer advocates and can feature either a single Principal Investigator or a duo. This initiative seeks to improve outcomes through comprehensive data analysis and patient engagement.
Breast Cancer

DoW Breast Cancer, Breakthrough Award Levels 1 and 2 (363670)

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
US $750,000 - US $3,350,000
The FY26 Breast Cancer Research Program's Breakthrough Award supports transformative research aimed at significant advancements in breast cancer treatment. This award offers various funding levels, including Population Science Studies, allowing for innovative approaches that can lead to clinical applications. Each application must align with overarching BCRP challenges, ensuring a focus on impactful research. The program acknowledges both individual and collaborative Principal Investigators, emphasizing the importance of timely submissions to avoid administrative issues.
Breast Cancer

Pocket Nurse Scholarship Fund

Pittsburgh Foundation
Private
United States
Approximately US $5,000
The Pocket Nurse Scholarship Fund, established by Pocket Nurse at The Pittsburgh Foundation, provides financial assistance to students pursuing education in Allied Health, Nursing, and Nursing Faculty. This initiative highlights the Foundation's commitment to supporting local students, especially those from marginalized backgrounds, as they strive to achieve their academic and career goals. With a minimum GPA requirement of 3.5, the program aims to empower the next generation of healthcare professionals.
Education - Higher Education Nursing Academic Scholarship Programs

CS: Youth Incentive Award

Coleopterists Society
Association/Society
United States
US $1,000
The Youth Incentive Award, established by the Coleopterists Society, encourages students in grades 7-12 to explore the fascinating world of beetles. Annually, up to $1200 is awarded, with two grants of $400 and $800 for junior and senior categories, respectively. Recipients also receive a subscription to The Coleopterists Bulletin. The program aims to promote beetle studies, develop essential life skills, and provide financial support for educational projects, fostering a passion for entomology among youth.
Entomology

Senator Paul D. Wellstone Muscular Dystrophy Specialized Research Centers (MDSRC)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Senator Paul D. Wellstone Muscular Dystrophy Specialized Research Centers (MDSRC) program is designed to enhance research on muscular dystrophy through a collaborative, center-based approach. By fostering interdisciplinary projects and providing essential training for emerging scientists, the MDSRCs aim to drive innovation in both basic and clinical research. Engaging patient and advocacy communities is a key component, ensuring research is patient-centered and informed by real-world needs. This initiative is supported by various legislative authorities.
Muscular Dystrophy

Scholarship Athletes of Stanislaus - Formerly Tom Mellis Memorial

Stanislaus Community Foundation
Private
United States
US $2,500

Stanislaus Community Foundation provides scholarship opportunities for students in order to help them achieve their educational and career goals. We believe that by investing in our students, we are investing in a brighter future for Stanislaus. 

Scholarship Athletes of Stanislaus - Formerly Tom Mellis Memorial

Open to high school graduating seniors participating in a Varsity sport. Must demonstrate strong academics, leadership qualities, and community service.

Award Amount:

  • $2,500
Education - Higher Education Sports & Athletics Career / College Preparation

Retina Society Underrepresented in Medicine (RESOURCE) Mentoring Program

The Retina Society, Inc.
Association/Society
United States
Up to US $5,000

The Retina Society, Inc.

The Retina Society was founded in 1968 exclusively for educational and scientific purposes concerning the diagnosis, care and treatment of diseases and injuries to the retina. The Retina Society began as an outgrowth of alumni meetings of Retina Associates, a retina practice founded in Boston in 1951 by Charles L. Schepens. Dr. Schepens is credited with establishing retina surgery as a sub-specialty.  

Our mission is to reduce worldwide visual disability and blindness by promoting the education and professional interaction of vitreoretinal specialists, providing optimal care for patients with vitreoretinal diseases, and encouraging, through clinical and basic research, the discovery and development of new means to further patient care.

Retina Society Underrepresented in Medicine (RESOURCE) Mentoring Program

The Retina Society Underrepresented in Medicine (RESOURCE) Mentoring Program was created to engage and interest ophthalmology residents from underrepresented populations* in research and in pursuing careers in the retina subspecialty through dedicated mentoring exposure. The program will pair ophthalmology residents from underrepresented backgrounds with Retina Society mentors, with the goal of providing the residents with research and career mentorship.

*The American Association of Medical Colleges definition of underrepresented in medicine is: "Underrepresented in medicine means those racial and ethnic populations that are underrepresented in the medical profession relative to their numbers in the general population." We define the following groups as underrepresented: Black (African American or African), Latino/Hispanic, American Indian, Alaska Native, Native Hawaiian or Pacific Islander. We will also be considering applicants from LGBTQIA+ and socioeconomically underprivileged backgrounds.

Mentors will work with their designated mentees on research projects that will be presented at the Retina Society Annual Meeting in 2027 and submitted for publication consideration. Mentors and mentees will be acknowledged at the Retina Society Annual Meeting.

Eye Diseases & Disorders Tutoring & Mentoring

Apple Crop Protection Request for Proposals

Washington Tree Fruit Research Commission
State/Local Government
United States
Unspecified amount
The Washington Tree Fruit Research Commission is inviting research proposals aimed at apple crop protection, emphasizing organic practices and pollinator protection. Key areas of focus include the management of pests like Codling Moth and Fire Blight, testing new crop protection products, enhancing soil health, and developing efficient monitoring techniques. Collaboration among institutions is encouraged, and projects should aim for practical industry applications to ensure sustainable and profitable tree fruit production.
Agricultural Crops Agricultural Pest Management Pollinator Conservation

Whole Foods Market Store Giving Program

Whole Foods Market
Corporate
Canada, United Kingdom +1 more
Unspecified amount
The Whole Foods Market Store Giving Program supports local communities by providing financial assistance to 501(c)(3) nonprofit organizations that focus on food access and environmental stewardship. This biannual program allows eligible organizations to apply via the Community Engagement Portal, although not all requests can be fulfilled due to high demand. Priority is given to those without recent funding, promoting sustainable community engagement.
Food Access & Hunger Environmental Stewardship

Biocodex Microbiota Foundation- Call for Projects USA

Biocodex Microbiota Foundation
Private
United States
US $50,000
The Biocodex Microbiota Foundation invites early career researchers in the microbiome field from U.S. institutions to apply for the 2024 grant. This initiative focuses on groundbreaking research into gut microbiota's role in human health and disease, particularly in areas like circadian rhythms and metabolic disorders. The grant supports operational costs, allowing for innovative projects aimed at fostering independent research careers in microbiota studies.
Microbiomes Digestive System Health & Diseases

Owen C. Meadows and Brenda J. Meadows Scholarship

Beckley Area Foundation
Private
United States
Unspecified amount

Beckley Area Foundation

Beckley Area Foundation was established in January 1985 by ten community-minded citizens. It began with a gift of $1.1 million from the Dr. Thomas Walker Memorial Health Foundation as “seed” money for this Raleigh County project. BAF assets have grown to over $70 million with over 500 different funds managed by our three trustee banks. Today, Beckley Area Foundation is one of West Virginia’s largest community foundations.

Since its inception, BAF has distributed over $23 million to charities and other worthy projects in the fields of education, public recreation, health & human services, the arts, animal services and beautification.

Scholarships

The Beckley Area Foundation proudly manages scholarship funds established by individuals, businesses, and organizations dedicated to helping students pursue higher education. Many of these scholarships are tailored for specific schools, fields of study, or graduates from local high schools, while others offer broader opportunities. No matter the path, our scholarships aim to support students from our region as they work toward achieving their educational goals.

Most of these scholarships must be awarded to students from our geographic area or at least preference given to such students. While the majority of scholarships benefit Raleigh County applicants there are others designated for Fayette, Summers, Webster, and Wyoming students. 

Owen C. Meadows and Brenda J. Meadows Scholarship

Must be resident of Raleigh County; Pursuing an accredited nursing program (including technical, baccalaureate or advanced nursing education programs); Merit and need based.​

This scholarship is not renewable.

Education - Higher Education Nursing Vocational & Trade Education

Cinderella’s Closet of NEPA Scholarship

Scranton Area Foundation Inc
Private
United States
Unspecified amount

Who We Are

Buiding a stronger, More Vibrant Community

For over 70 years, the Scranton Area Community Foundation has served Northeastern Pennsylvania as a steward of charitable resources, a grantmaker, and a catalyst for positive change. Guided by our core values of collaboration, trust, integrity, innovation, and inclusivity, we work to ensure that our communities thrive with opportunities for all.

This scholarship is awarded to a female or female-identified student from a high school in Lackawanna, Luzerne, Pike, Susquehanna, Wayne, or Wyoming county who has 50 or more documented volunteer hours and and who has a GPA of 3.0 or higher.

Education - Higher Education Women & Girl Services Volunteerism & Philanthropy

Post-Doctoral Fellowships

American Parkinson Disease Association
Private
United States
Up to US $150,000
The American Parkinson Disease Association offers Post-Doctoral Fellowships to support research focused on Parkinson's disease. These fellowships, lasting two years, provide up to $75,000 per year to eligible post-doctoral trainees at U.S. institutions. Applicants must have completed their MD, PhD, or residency within two years prior to the award. Funding can cover direct research costs, but not travel or publication expenses over $1,000, ensuring resources are allocated effectively for impactful research.
Parkinson’s Disease

Greg Legg NEPA Diamond Scholarship

Scranton Area Foundation Inc
Private
United States
Unspecified amount

Who We Are

Buiding a stronger, More Vibrant Community

For over 70 years, the Scranton Area Community Foundation has served Northeastern Pennsylvania as a steward of charitable resources, a grantmaker, and a catalyst for positive change. Guided by our core values of collaboration, trust, integrity, innovation, and inclusivity, we work to ensure that our communities thrive with opportunities for all.

This scholarship is awarded to a graduating senior from a high school in Lackawanna, Luzerne, Wayne, or Pike county who plays baseball and plans to continue playing in college.

Education - Higher Education Sports & Athletics Baseball & Softball

Prader-Willi Syndrome Mini-Fellowship Grant ( up to $25,000)

Prader Willi Syndrome Association (Usa)
Private
United States
Up to US $25,000
The Prader-Willi Syndrome Mini-Fellowship Grant aims to enhance understanding of Prader-Willi Syndrome (PWS) through clinical proctorships. Offering up to $25,000 USD, this grant supports providers in shadowing experts in PWS while engaging in an academic project. PWSA | USA, dedicated to advancing research since 1983, focuses on high-impact projects that translate biomedical knowledge into effective treatments, ultimately improving the lives of those affected by PWS.
Endocrine & Metabolic Diseases Neurological Diseases & Disorders

FOXG1 Scientific Research Project Grants

FOXG1 RESEARCH INC
Private
Countries
Unspecified amount

About

What is FOXG1 Syndrome?

FOXG1 syndrome is a rare genetic neurodevelopmental disorder caused by a mutation in the FOXG1 gene. FOXG1 gene is one of the first and most important genes for early brain development and when impaired, causes developmental disabilities as well as medical complexities, including epilepsy.

Every child born with FOXG1 syndrome is unique as FOXG1 manifests as a spectrum where symptoms and severity vary between individuals. Our patient data shows characteristics of children with FOXG1 syndrome include: non-speaking, non-ambulatory, experience seizures, feeding problems, cortical vision impairment, movement disorders, and developmental delays. Less-severely-affected FOXG1 children often present with (ASD) Autism Spectrum Disorder as FOXG1 is an autism related gene. FOXG1 syndrome is found equally among both females and males and is geographically more prevalent where diagnostic testing is more advanced. 

Our Story & Mission

When our children were diagnosed with FOXG1 syndrome, we were told there was nothing we could do. No treatments, no concerted research underway, no roadmap. Just a devastating diagnosis for a disorder few had ever heard of.

But we refused to accept that. 

Research Assets & Grants

FOXG1 Scientific Research Project Grants

The FOXG1 Research Foundation is providing grants to scientists to deepen the understanding of the biology of FOXG1 with the goal of identifying innovative therapeutic strategies and finding a cure.

For the next few years, these are the strategic focus areas:

  • Experiments designed to understand when, where, and levels of FOXG1 needed for normal brain development in mice
  • Experiments designed to understand the biophysical properties of FOXG1 mutations
  • Experiments designed to gain insights into the molecular and cell biological pathways regulated by FOXG1  
Rare Diseases Neurological Diseases & Disorders

RRF Pilot Study Grants

Retina Research Foundation
Private
United States
Unspecified amount

Retina Research Foundation

Across the nation, there were only a handful of voluntary groups with the will and the means to tackle retinal disdorders. Retina Research Foundation, established in 1969, was one of those organizations. By the 1980s, RRF had become a voice for retina research in an effort to reduce the incidence of retinal disease, which was fast becoming the leading cause of blindness in developing countries.

Undaunted, the Foundation steadily raised funds each year for vision scientists who were nationally recognized for their work in retina research. Government funding for eye research increased dramatically, and the field of retina research matured. As this body of knowledge grew, RRF programs were expanded to include major awards that recognize established retina scientists and contribute to their ongoing research. The Foundation also developed scientific exchange programs to disseminate knowledge of the dramatic advances that were being made in the laboratory.

RRF Pilot Study Grants

The mission of the Retina Research Foundation is to reduce retinal blindness worldwide by funding programs in research and education. As a public charity, RRF raises funds from the private sector and the investment of its endowment funds.

RRF is currently welcoming pilot study grant applications for the 2027 grant period. Each grant application must be signed by the principal investigator and either their Department Chair or Dean of Research.

Eye Diseases & Disorders Vision Impairment Care & Services

Antoinette Lierman Medlin Scholarship (Energy Geology Division)

Geological Society of America (GSA)
Association/Society
United States
US $1,500 - US $2,000
The Antoinette Lierman Medlin Scholarship, administered by the Geological Society of America, supports graduate students in coal science. It offers two awards: $2000 for laboratory research and $1500 for fieldwork. This scholarship aims to recognize and assist students in completing their research projects successfully. Contributions from personal and corporate sponsors help sustain this valuable fund, encouraging commitment to advancing knowledge in energy geology.
Petrology Geochemistry & Biogeochemistry Mining Engineering

FSR Early Career Fellowship Grant

Foundation For Sarcoidosis Research
Private
United States
US $150,000
The FSR Early Career Fellowship Grant supports early-stage researchers in sarcoidosis, fostering skills and knowledge advancement. With $150,000 over two years, this grant aims to enhance medical care and scientific understanding of the disease. Eligible applicants, including international candidates, must present innovative study proposals and demonstrate a commitment to sarcoidosis research. FSR encourages transitions from fellowships to faculty positions, thereby strengthening academic credentials and promoting impactful research contributions.
Respiratory Diseases & Systems Immune System Diseases

ISTAART Grant Program for Conferences and Convenings (IGPCC) Grant

Alzheimer's Association
Private
Algeria, Andorra +160 more
Up to US $20,000
The ISTAART Grant Program for Conferences and Convenings (IGPCC) Grant, funded by the Alzheimer's Association, aims to support innovative initiatives that enhance research discussions among Professional Interest Areas (PIAs). This funding mechanism encourages collaboration and networking opportunities for ISTAART members, allowing for the organization of educational workshops and conferences. Grants of up to $20,000 are available, with a focus on new projects that haven't received funding in the last 24 months. Applications are reviewed year-round.
Dementia & Alzheimer’s Disease

Pat R. Gereau R.N. Scholarship

Tulsa Community Foundation
Private
Tulsa County, Oklahoma, United States
Unspecified amount

Scholarship funds at TCF annually provide approximately $20 million in educational aid for students at institutions of higher learning. Each donor or group of donors determines the conditions for which the scholarships are awarded. The diversity of eligibility criteria reflects the variety of donor motivations to create or support scholarship funds.

Pat R. Gereau R.N. Scholarship

Available to students who are in an undergraduate program of study and pursuing a career in nursing at an accredited U.S. college, university, technical program or trade school in Tulsa, Oklahoma area.

Education - Higher Education Nursing Vocational & Trade Education

Child Well-Being National Program

Doris Duke Foundation Inc.
Private
United States
Unspecified amount
The Child Well-Being Grant Program, established by the Doris Duke Foundation, focuses on promoting the healthy development of children and preventing abuse. With a commitment to addressing systemic inequities, the program supports initiatives that strengthen social service systems and foster partnerships to enhance access to services. It prioritizes funding for projects that encourage community-based interventions and the development of future leaders dedicated to improving child welfare, ensuring all children have the opportunity to thrive in safe and supportive environments.
Child Welfare Services Early Childhood Development Child Abuse & Neglect

Emergency Department Alternatives to Opioids Program

Substance Abuse and Mental Health Services Adminis
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Emergency Department Alternatives to Opioids Program aims to implement practices that offer alternatives to opioid treatments in hospitals. This initiative focuses on reducing the harmful consequences of opioid use for pain management, promoting safer treatment options, and minimizing the risk of opioid misuse and overdose. Specifically, it targets healthcare organizations to enhance their pain care strategies, ultimately contributing to better patient safety and health outcomes.
Addiction & Substance Use Disorders Health Care Access & Delivery Preventative Healthcare

APA Congressional Fellowship

American Psychological Foundation Inc
Private
United States
US $75,000 - US $90,000
The APA Congressional Fellowship offers psychologists a unique opportunity to engage in public policy, enhancing the application of psychological knowledge in government. Over a year, fellows work alongside Congress members, drafting legislation and participating in oversight activities. The fellowship is available for APA members, with stipends ranging from $75,000 to $90,000, in addition to health insurance reimbursement and professional development funds. This initiative aims to support psychologists interested in societal challenges and policy issues.
Public Policy Psychology Health Policy & Advocacy

NCB - Botany Research Scholarship Program

Northern California Botanists
Association/Society
United States
US $1,500
The NCB - Botany Research Scholarship Program, offered by Northern California Botanists, targets undergraduate and graduate students pursuing research in botany and plant ecology. Scholarships of $1,500 support independent study, thesis, or dissertation projects within a specific geographic area of Northern California. Eligible applicants may reapply for funding for up to four years. This initiative aims to foster academic careers in botany and promote valuable ecological research.
Plant Science Ecology Botanical Conservation

Bridgestone Americas Trust Fund: Adaptive Sports in Schools Mobility Grants

Bridgestone Americas Trust Fund
United States
US $25,000

Adaptive Sports in Schools Mobility Grants

Request for Proposals

More than 7 million students in the U.S. receive special education services for disabilities in public schools. A 2010 study by the U.S. General Accountability Office found that students with disabilities participated in athletics at significantly lower rates than their peers. Currently, 2,490 k-12 public schools in the U.S. are members of the American Association of Adaptive Sports Programs schools and have adaptive sports programs for students.

The Bridgestone Americas Trust Fund seeks public schools pursuing funding to start adaptive sports programs or increase access to adaptive sports and equipment for children and youth. Bridgestone is offering eight $25,000 “mobility” grants to organizations that can establish new athletic programming for students with disabilities. Organizations must articulate a clear plan to provide access to new athletic programs for students with disabilities in one or more public schools for students grades K-12.

Education - K through 12 Sports & Athletics Youth Services +1 more

Diversity Leadership Fellowship

American Psychiatric Association Foundation
Private
United States
Unspecified amount

American Psychiatric Association Foundation

There is no health without mental health. The APA Foundation is working in your community to provide the support and resources we all need to prioritize mental wellbeing where you live, learn, work, worship, and play.

Backed by the medical expertise of the APA and industry-leading strategic partners, we administer community-changing programs, public education campaigns, grants, and awards aimed at increasing mental health literacy, connecting individuals to needed care, and shifting attitudes toward mental health.

Our Mission is to promote the mental health and well-being of individuals and communities. Our Vision is a mentally healthy nation for all – where we live, learn, work, worship, and play.

Diversity Leadership Fellowship

The Diversity Leadership Fellowship identifies and motivates minority psychiatry residents or those interested in minority and vulnerable populations to become well equipped to teach, administer, and provide culturally competent, evidence based mental health and substance abuse services to diverse minority groups and at-risk populations. These populations include—but are not limited to—American Indians/Native Alaskans, Asian Americans/Native Hawaiians/Native Pacific Islanders, Blacks/African Americans, Hispanics/Latinos, LGBTQ, and religious minorities. Program Benefits:

  • Sponsorship to attend a minimum of four APA meetings:
    • Two APA Annual Meetings
    • Two Fellowship Forums
  • Develop leadership skills in the field of psychiatry and advance understanding of the life experiences of racial ethnic minority communities
  • Gain an understanding of APA/APAF Governance through observation and service on an APA Council, Committee, or APAF initiative
  • Have the opportunity to sit on the APAF Board of Directors as a non-voting member (one Diversity Leadership fellow allowed)
  • Cultivate a professional network with psychiatrists interested in minority mental health and services through exclusive events and engagements with APA leaders. Establish relationships and peer-mentorship with a diverse group of resident fellows with similar career interests and goals
Medical Education & Professional Training Mental Health & Psychiatric Diseases Diversity, Equity & Inclusion

Unrestricted Grants for Nonprofits in North Carolina Highlights

Looking for unrestricted grants for nonprofits in North Carolina?


Read more about each grant below or start your 14-day free trial to see all unrestricted grants for nonprofits in North Carolina recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Unrestricted Grants for Nonprofits in North Carolina

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Unrestricted grants for nonprofits in North Carolina grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

70 Unrestricted grants for nonprofits in North Carolina over $25K in average grant size

51 Unrestricted grants for nonprofits in North Carolina over $50K in average grant size

35 Unrestricted grants for nonprofits in North Carolina supporting general operating expenses

200+ Unrestricted grants for nonprofits in North Carolina supporting programs / projects

1,000+ Grants on Instrumentl focused on Environment

2,000+ Grants on Instrumentl focused on Community Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Unrestricted grants for Nonprofits in North Carolina?

Most grants are due in the first quarter.

Q1
30.4%
Q2
22.4%
Q3
26.2%
Q4
21.1%

Typical Funding Amounts

What's the typical grant amount funded for Unrestricted Grants for Nonprofits in North Carolina?

Grants are most commonly $17,500.

$500 $500 Min.
$17,500 $17.5 K Median
$477,452 $477.5 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for North Carolina?

Grants are most commonly $131,121.

$131,121

Total Number of Grants

What's the total number of grants in Unrestricted Grants for Nonprofits in North Carolina year over year?

In 2024, funders in North Carolina awarded a total of 70,602 grants.

2022 63,850

2023 62,335

2024 70,602

Top Grant Focus Areas

Among all the Unrestricted Grants for Nonprofits in North Carolina given out in North Carolina, the most popular focus areas that receive funding are Education, Human Services, and Philanthropy, Voluntarism & Grantmaking Foundations.

1. Education

2. Human Services

3. Philanthropy, Voluntarism & Grantmaking Foundations

Funding Over Time

How is funding for Unrestricted Grants for Nonprofits in North Carolina changing over time?

Funding has increased by 15.49%.

2022 $7,927,620,616

2023 $7,987,830,464
0.76%

2024 $9,224,796,270
15.49%

North Carolina Counties That Receive the Most Funding

How does grant funding vary by county?

Durham County, Orange County, and Mecklenburg County receive the most funding.

County Total Grant Funding in 2024
Durham County $2,942,551,198
Orange County $2,549,339,233
Mecklenburg County $1,468,677,341
Wake County $1,122,908,782
Buncombe County $444,853,701

Related Grants in North Carolina

Browse Other Nonprofit Operations & Capacity Grants in North Carolina

Browse Grants For Nearby Locations

Browse Grants by Major US Cities within North Carolina