Best Grants for Preschools in Northern Mariana Islands

The National Institute of Environmental Health Sciences (NIEHS) is launching a funding opportunity for research hubs focused on the health impacts of extreme weather. This initiative encourages multidisciplinary teams to engage with community partners on issues such as wildfire smoke and extreme heat. Emphasizing collaboration, the program aims to develop scalable solutions and measurable public health outcomes, leveraging resources and expertise across institutions to address climate-related health challenges effectively.

The SPARK-EHS initiative aims to broaden the reach of NIEHS training by launching innovative environmental health programs for predoctoral trainees at institutions without recent NIEHS T32 funding. This initiative focuses on research regarding the impact of the environment on biological systems and seeks to translate findings into practical health solutions. Eligible institutions will receive support for developing and implementing these targeted training programs, fostering advancements in environmental health research.

The NIH Blueprint and BRAIN Initiative Diversity Specialized Predoctoral to Postdoctoral Advancement in Neuroscience (D-SPAN) Award aims to support underrepresented graduate students in neuroscience. This two-phase program facilitates the completion of doctoral dissertations and transitions students to postdoctoral positions, enhancing their career development and fostering their growth into independent neuroscience researchers. Applications are due by 5:00 PM local time of the applicant's organization.

The National Institute of Nursing Research (NINR) plans to publish a funding opportunity announcement for Community-Partnered Nursing Research Centers (P20 Clinical Trial Optional). This initiative aims to strengthen nursing-led programs that foster community-partnered research addressing significant health issues. By enhancing interdisciplinary research capacities, the program will establish centralized resources in nursing schools, build expertise in community partnerships, and support nurse-led teams in developing, implementing, and evaluating impactful research projects.

The All of Us Research Program seeks to advance its mission by enabling access to biospecimens stored in the All of Us supported Biobank for researchers to conduct assays to evaluate associations between biomarkers and chronic diseases and add data to the All of Us resource for broad use by researchers. Biomarker analysis includes, but is not limited to, biomarker discovery; biomarker validation; novel disease stratification; and multiomics integration for disease risk, diagnosis, and prognosis, in support of advancing precision medicine. The All of Us Research Program is a historic effort to enroll 1 million participants who share data to accelerate research and medical breakthroughs, and enable individualized prevention, treatment, and care. Researchers use data from the program to learn more about how individual differences in lifestyle, environment, and genetics can influence health and disease.Grant authorities that allow the All of Us Research Program to forecast this opportunity are as follows: 42 USC 241 and 284.

The NCCIH Natural Product Mid Phase Clinical Trial (R01 Clinical Trial Required) invites applications for mid-phase clinical trials involving natural products like botanicals and dietary supplements. The goal is to advance clinical testing through robust preliminary data, ensuring these products demonstrate measurable impacts on target engagement. Submission deadlines span from March 2024 to October 2026. Applications must focus on optimizing doses and identifying patient responders to inform future efficacy trials, aligning with NCCIH's research priorities.

The NCCIH Natural Product Early Phase Clinical Trial Award (R33 Clinical Trial Required) promotes innovative clinical trials on natural products, such as botanicals and dietary supplements. This funding opportunity supports studies that demonstrate significant scientific rationale and preliminary evidence for efficacy. Applications can explore various delivery methods and combinations with existing treatments to enhance outcomes. Funding is available for up to three years, aimed at bridging basic science discoveries into practical clinical applications.

The Mobile Learning Fund provides grants to adult literacy programs in the U.S. and Canada, enabling access to digital learning solutions. These grants support various online learning tools, such as New Readers Press, Learning Upgrade, and EnGen, aimed at enhancing literacy, math, and digital skills. Eligible programs must implement the solutions within 30 days and ensure active learner engagement. This initiative empowers educators to expand their reach and improve student outcomes through innovative digital resources.

The NCCIH Natural Product Early Phase Clinical Trial Phased Innovation Award supports investigator-initiated clinical trials of natural products, including botanicals and dietary supplements. This funding opportunity aims to validate the pharmacokinetics and bioavailability of these products over three years in a phased approach. Successful trials will provide crucial data for further development and clinical application, emphasizing the importance of scientifically driven research in natural product efficacy.

The Desalination and Water Purification Research Program, led by the Bureau of Reclamation, aims to enhance water supply through innovative research in water treatment technologies. This initiative seeks proposals for laboratory and pilot-scale projects that demonstrate significant benefits and commercialization pathways. By addressing cost and energy barriers, the program aligns with federal priorities to improve resource management and support the development of sustainable water solutions for the American public.

The WaterSMART Enhancing Water Resources Projects program invites eligible entities to secure funding for initiatives that enhance water resource management across various sectors, including conservation, infrastructure improvement, and watershed restoration. Priority is given to projects that collaboratively address community needs and yield significant environmental benefits. This funding opportunity aligns with federal priorities aimed at optimizing resource use and improving grant oversight, as outlined in recent executive orders.

The NCDDG program supports innovative research aiming to discover and develop new treatments for mental disorders, including substance use and alcohol use disorders. This initiative encourages collaborations between academic and industry partners to advance neurostimulation techniques and drug/device development. Applicants are invited to submit proposals that focus on specific projects utilizing the U01 mechanism, with a clear emphasis on rationally designed candidate agents and cutting-edge technologies. Letters of Intent are encouraged 30 days prior to the submission deadline.

The NIAID is dedicated to advancing research on medical countermeasures against chemical and radiation threats, focusing on innovative technologies to diagnose and treat exposure effects. The initiative promotes the development of models, biomarkers, and devices that enhance survival and reduce morbidity during public health emergencies. It supports preclinical efforts to address injuries from designated Chemicals of Concern, emphasizing the need for effective solutions in civilian mass casualty scenarios.

The T32 Training Program aims to enhance the participation of individuals from underrepresented backgrounds in cardiovascular, pulmonary, hematologic, and sleep disorders research. This initiative, funded by the NIH, supports institutions committed to diversity and health disparity populations. By providing training opportunities for students and postdoctoral trainees, the program seeks to foster research that improves health outcomes for these communities. Note that appointed trainees cannot lead independent clinical trials but can gain experience in trials conducted by mentors.

The NIAID is focused on advancing the research and development of next-generation malaria vaccines, aiming to leverage innovative vaccine design techniques. This initiative not only aims to enhance malaria prevention but also serves as a model for combating other mosquito-borne diseases. By utilizing cutting-edge methods such as structure-based immunogen design and combination vaccines, the program seeks to significantly reduce both parasite infection rates and the overall disease burden associated with malaria.

The National Cooperative Drug/Device Discovery/Development Groups (NCDDG) program invites applications to foster innovative research in treating mental disorders and substance use issues. This initiative promotes collaboration between academia and industry, supporting diverse, multidisciplinary projects aimed at developing rational therapies and neurostimulation techniques. Applicants are encouraged to submit Letters of Intent 30 days before the proposal deadline to enhance project alignment with funding goals.

• Innovative: An approach that brings fresh thinking, tools, or models to homeownership in ways that challenge the status quo and demonstrate a disruptive, future-oriented vision with potential to inspire or shift broader field practice.
• Impactful: A solution with meaningful potential to expand homeownership through knowledge and action, featuring clear and measurable progress indicators that demonstrate capacity to shift trajectories for low- and moderate-income households.
• Bridge-Building: An initiative that effectively connects and unifies a wide range of stakeholders, fostering meaningful collaboration across sectors or perspectives. The strongest submissions will reflect strong community partnerships across the housing ecosystem.
• Durable: A sustainable pathway that addresses root causes of homeownership barriers rather than just symptoms, with compelling evidence of potential to elicit robust support from broad private, philanthropic, and public funding sources over time.

The Cooperative Program for Modeling Clinical Transplantation, supported by the NIAID, aims to enhance human solid organ transplantation through innovative in-vitro and in-vivo systems. This program encourages applications utilizing new approach methods (NAMs) and refined mouse models to improve clinical translation. Emphasis is placed on developing models that address clinical obstacles and reduce reliance on nonhuman primates, while promoting data sharing to foster reproducibility and best practices in research.

The Title XVI Water Reclamation and Reuse Projects, funded by the US Department of the Interior's Bureau of Reclamation, invites proposals for innovative water reuse solutions. This program enhances water supply reliability and supports sustainable practices for urban and agricultural communities. By leveraging Federal and non-Federal resources, the initiative aims to address water scarcity and improve hydropower reliability, aligning with national priorities for energy and resource management.

The Rapid Response Opioid and Pain Management ECHO Funding Opportunity by the Association of State and Territorial Health Officials (ASTHO) aims to enhance clinician training in effective pain management strategies. This initiative focuses on non-opioid treatments, substance use screening, and risk reduction counseling, promoting compassionate care while addressing public health challenges and ensuring continuity for patients affected by prescription disruptions. The program seeks to improve overall health outcomes and reduce risks associated with opioid use.

This funding opportunity aims to enhance the development of medical products in rare diseases through innovative natural history studies. By generating high-quality data, the FDA seeks to bridge critical knowledge gaps and eliminate barriers in rare disease research. The initiative focuses on diseases with unmet needs, fostering significant impacts for those affected and facilitating the development of effective therapeutic solutions.

The NARMS Cooperative Agreement Program aims to enhance antibiotic resistance surveillance in retail food specimens. Funded by the FDA, this initiative strengthens the National Antimicrobial Resistance Monitoring System established in 1996. By improving detection methods and expanding sampling sites, the program seeks to protect public health and align with NARMS objectives, ultimately combating the growing threat of antibiotic resistance in food commodities.

The RFA-FD-23-001 funding opportunity aims to support clinical trials for orphan products targeting rare diseases. It focuses on evaluating the efficacy and safety of treatments to address unmet medical needs. By promoting innovative and collaborative trial designs, the FDA seeks to enhance the approval rates of effective therapies for rare conditions, ultimately benefiting patients and advancing drug development in this critical area.

The Core State Injury Prevention Program (Core SIPP) aims to enhance public health infrastructure and partnerships to prevent unintentional injuries through data-driven strategies. Focusing on key areas such as traumatic brain injury, falls among older adults, and drowning, it seeks to improve community safety by strengthening data use and fostering collaborations. This initiative supports states in identifying local injury concerns, thus promoting evidence-based prevention approaches and increasing the capacity for sustained public health actions.

The NIH's Investigator-Focused Award (Parent R35) aims to support research programs for investigators at all career stages, including Early Stage Investigators. This funding provides stability and freedom in research, allowing for innovative and ambitious studies without the constant pressure of securing new grants. Key benefits include flexibility in research direction, opportunities to tackle significant questions, and a greater potential for scientific breakthroughs, fostering a robust research environment.

The NIH Director’s Transformative Research Award supports individual scientists or groups of scientists proposing bold, groundbreaking, exceptionally innovative, original, and/or unconventional research with the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or develop transformative technologies. Applications in any area within the biomedical sciences are welcome. No preliminary data are required. Projects must clearly demonstrate, based on the strength of the logic, a compelling potential to produce a major impact in a broad area of relevance to the NIH. The NIH Director’s Transformative Research Award is a component of the High-Risk, High-Reward Research (HRHR) Program of the NIH Common Fund.

The NIDCD Research Dissertation Fellowship for Au.D. Audiologists (F32) supports rigorous biomedical research training and dissertation research for doctoral candidates in clinical, behavioral, or biomedical sciences. Funded by the NIH, this fellowship aims to enhance research capabilities and knowledge in the field of audiology. Key deadlines for applications include April 8, August 8, and December 8 for the years 2025 to 2027, ensuring timely opportunities for aspiring researchers.