Best Grants for International Development in Pennsylvania

The Ruth Danley and William Enoch Moore Charitable Fund Grant is a private foundation based in Pittsburgh, established in 1992. It focuses on philanthropy, specifically supporting K-12 education for Native American children living on reservations. The foundation directs its grants primarily to regions preferred by donors, including several states in the Northeast and Midwest, aiming to improve educational opportunities and foster community development in underserved populations.

The Patient-Centered Outcomes Research Institute (PCORI) intends to issue a Broad Pragmatic Studies (BPS) PCORI Funding Announcement (PFA) on Aug. 4, 2026, seeking to fund high-impact, patient-centered comparative clinical effectiveness research (CER) projects. This preannouncement provides potential applicants additional time to identify collaborators; obtain patient and stakeholder input on potential studies; and develop responsive, high-quality applications. 

Patient-centered CER compares at least two available health treatments, services or care delivery strategies. PCORI seeks proposals that compare clinical interventions (e.g., pharmacological and nonpharmacological treatments, screening and diagnostic approaches) and healthcare delivery system interventions (e.g., workforce, technologies, healthcare service delivery designs) to evaluate potential benefits and harms of different treatment and care delivery options, thus generating evidence that empowers patients, caregivers and the broader healthcare community with information to make informed choices that reflect their needs and preferences. 

Asia-Pacific Network for Global Change Research

The Asia-Pacific region, home to over half the world's population, faces challenges due to its development goals, which strain natural resources, communities, and cultural heritage. These issues are exacerbated by adverse environmental changes. While research has shed light on these problems, it's clear that more challenges lie ahead. The Asia-Pacific Network for Global Change Research (APN) is well-positioned to generate new knowledge and solutions for these evolving global change and sustainability issues by supporting collaborative research and scientific capacity development activities, particularly those aimed at training the next generation of early career professionals.

APN 2025 Call for Proposals: CAPaBLE Programmes

CAPaBLE, our scientific capacity development programme, aims to enhance the capacity of scientists, policymakers and practitioners to assess global change issues, and explore options to resolve issues towards achieving sustainability. Through CAPaBLE, we support activities that enhance capacity at individual, organizational and systemic levels.

Activities of interest under the CAPaBLE Programme

APN supports CAPaBLE activities that enhance existing capacities of developing countries at three levels of individual-based capacity development; group, organisation, network-based capacity development; and societies, governance, and system level capacity development. APN accepts CAPaBLE proposals that engage 1 or more member/approved countries. Proposals must address one or more of the following activities:

SCIENTIFIC CAPACITY DEVELOPMENT ACTIVITIES that promote the following approaches related to one or more of the six thematic areas of APN:

• Utilising and strengthening existing capacity, 
• Creating opportunities to use/instil capacity, 
• Developing new capacity through innovative approaches.

AWARENESS-RAISING AND DISSEMINATION activities through policy- and decision-making communities, civil society, and/or the general public.

SCIENCE-POLICY interfacing in the context of the priority topics.

CAPACITY DEVELOPMENT PARTNERSHIP ACTIVITIES that contribute to the capacity development components of the evolving global change arena, including the UNFCCC Paris Agreement, IPCC, IPBES, post-2015 Sustainable Development Goals, Sendai Framework for Disaster Risk Reduction, and the UN Decade of Ocean Science, and ongoing and new global change and sustainability research programmes.

Activities geared towards using SCIENCE COMMUNICATION to disseminate knowledge generated from projects, particularly to non-science audiences.

The Santander Charitable Sponsorship Program focuses on supporting low- to moderate-income communities primarily in the Northeast and Florida. With a commitment of $100 million in charitable giving, the program addresses key community development needs, including affordable housing, job creation, financial education, and disaster relief. Eligible organizations must have IRS 501(c)(3) status or be public agencies, demonstrating capacity to meet community needs. Unsolicited applications are not accepted.

The Climate Change Investment Initiative Grant Program, funded by the Exelon Foundation, aims to support innovative start-ups focused on climate change solutions within Exelon's service territories. With a commitment of $20 million over ten years, the program promotes not only environmental sustainability but also social equality and economic prosperity. Eligible businesses can benefit from substantial equity investments and valuable in-kind services. The initiative seeks to empower diverse leadership teams, particularly those representing women and minorities, to drive impactful change.

The RMEF Grant Program lies at the core of advancing our mission.

RMEF established the program in 1986 to provide financial and logistical support to projects that align with our priorities and goals. Grant funds raised by RMEF members, volunteers and generous donors from across the country translate into significantly more conservation accomplishment when matched with partner funds. The RMEF Grant Program also aims to build recognition for RMEF’s work, grow engagement, and boost local fundraising efforts.

Governed by clear guidelines and criteria, the RMEF Grant Program seeks to foster meaningful collaborations and long-term impacts in the conservation of natural resources and outdoor traditions. Grant project partners include federal, state, local, and tribal wildlife and land management agencies, private landowners and local stakeholders, sportsmen and women, and conservation organizations, universities, foundations and the outdoor industry. Eligible projects primarily focus on habitat stewardship, land conservation and access, wildlife management, and hunting heritage.

We support organizations recognized by the Internal Revenue Service (IRS) as a 501(c)3 entity, federal, state, local, or tribal government entities, sportsmen’s organizations, or educational institutions. All applicants must have a Federal Employer Identification Number (EIN) issued by the IRS. RMEF does not offer grants to individuals.

Wildlife Management and Research

RMEF funds wildlife management and research to keep big game healthy and thriving, including disease surveillance, big game-friendly fencing, road management, and scientific studies that expand our understanding of big game habitat, movement, interactions, and overall herd health.

RMEF’s 2026 priorities include:

• Research on migration + connectivity, critical habitat + nutrition, big game population trajectories, challenges to big game populations, and big game management solutions
• Big Game-Friendly Fencing

The Wellness Across the Lifespan Grant supports the health of communities by providing access to nutritious food and essential nutrition education. Grants ranging from $5,000 to $10,000 are awarded to 501(c)(3) nonprofits in areas where Sprouts Farmers Market operates. This funding emphasizes health and nutrition education, as well as programs that promote healthy lifestyles and nutrition security, ultimately benefiting adults and vulnerable populations.

The UPMC Administrative Fellowship Program is a two-year opportunity designed for graduate students passionate about healthcare management. Participants engage with executive leadership through rotations, gaining hands-on experience in various health sectors. The program offers competitive salaries, benefits, and potential reimbursement for conference travel. UPMC is dedicated to developing future leaders in healthcare, emphasizing training and professional growth within its administrative fellowship.

The Ethnic Minorities and Women’s Internship Grant supports entry-level athletics administrative positions for one academic year, promoting diversity in NCAA Division II. It provides $30,000 for intern salaries and $3,000 for professional development, benefiting six schools annually from a total budget of $180,000. Eligible applicants must be active NCAA members, with a focus on enhancing ethnic minority and gender representation in athletics administration. This initiative encourages professional growth and compliance in diverse environments.

The Main Street Matters program aims to enhance downtown areas and neighborhoods through façade grants that encourage private investment and support revitalization efforts. Eligible local governments and organizations can apply for funding to improve exterior building aesthetics, ensuring vibrant and secure communities. The program emphasizes matching funds and adherence to design guidelines to maximize impact. With a maximum grant of $100,000, it serves as a flexible tool for community and economic development.

The Melville Alexander Eberhardt Memorial Fund, established by The Pittsburgh Foundation, aims to provide scholarship assistance to deserving high school graduates from Pennsylvania. Founded in 1945, The Pittsburgh Foundation promotes community impact, equity, and opportunity through its philanthropic efforts. This fund specifically supports students who demonstrate financial need, maintain a minimum GPA of 3.0, and plan to attend an accredited vocational or academic institution. It is a vital resource for fostering educational advancement in the region.

Armstrong County Technical School Scholarship

The purpose of the Armstrong County Technical School Scholarship Fund is to provide funds for scholarships for students pursuing a course of study in the trade arts at an accredited career school, vocational technical school or community college located in the Commonwealth of Pennsylvania.

The Foundation hopes that this program will encourage many of our community’s most talented students to consider pursuing occupations in the region following graduation.

The Express Health Information Outreach Awards aim to enhance public health by increasing access to biomedical information for U.S. health professionals and the general public. These awards support projects that improve health information literacy among consumers and caregivers, ensuring they can effectively find and utilize health information. Focused on partnerships and outreach to underrepresented communities, the initiative seeks to promote healthy behaviors, prevent illness, and improve health outcomes through informed decision-making.

About PA IOLTA

The core mission of the Pennsylvania Interest on Lawyers’ Trust Accounts (IOLTA) Board is to support the provision of civil legal services to the Commonwealth’s poor and disadvantaged. The IOLTA Board is a not-for-profit organization operating under the jurisdiction of the Supreme Court of Pennsylvania.

How Does the IOLTA Program Work?

The IOLTA program is simple. Clients and others frequently transfer moneys to attorneys to hold. When the amount is large or if the funds will be held for an extended period of time, attorneys invest them for the benefit of the client. But when the funds are small or expected to be held for a short time, they cannot practically be invested to benefit the client. Pennsylvania Rule of Professional Conduct 1.15 requires attorneys to deposit nominal and short-term fiduciary funds in interest-bearing IOLTA accounts. The attorneys’ banks transfer the interest earned on IOLTA accounts to the Pennsylvania IOLTA Board.

How is the Money Used?

Upon approval of the Supreme Court of PA, the Board makes grants annually to non-profit organizations, law school clinical programs, and administration of justice projects that provide civil legal services free of charge to the poor and disadvantaged.

Grants

The Pennsylvania IOLTA Board carries out its mission to financially support the delivery of civil legal aid to low-income and disadvantaged Pennsylvanians through the careful administration of various revenue sources, both court-directed and legislatively-directed. Upon approval of the Supreme Court of Pennsylvania, the IOLTA Board makes grants annually to qualified legal aid organizations across the state, Pennsylvania’s nine law school clinical and externship programs, and administration of justice projects, all of which provide legal assistance to low-income individuals and families facing a civil legal crisis where basic human needs, such as shelter, food, medicine and safety, are at stake.

Specialized Legal Services Grant Program

These discretionary grants – often referred to as “zone grants” – support the delivery of specialized legal services to targeted groups of people such as the disabled, non-English speaking communities, and victims of domestic violence. Funding is allocated to geographic zones based on the proportion of people living in poverty throughout the state. Applicants compete with one another in the zone where the proposed services would be delivered. Learn more about the geographic boundaries of our funding zones by viewing the IOLTA Funding Zone Map.

Service Objects In-Kind Grants support non-profit organizations dedicated to environmental conservation and sustainability. By leveraging their data validation services, they aim to assist projects that promote ecological health and responsible resource management. The program prioritizes applications with clear, measurable objectives and impactful outcomes within one to three years. Organizations with 501(c)(3) status in the U.S. are eligible, while initiatives lacking detailed plans or focusing on generalized education will not qualify. This grant fosters community involvement in environmental stewardship.

Wyoming County Community Health

The Community Health Foundation identifies, selects and invests in programs and organizations that will improve the health and wellness of people in Wyoming County, PA and surrounding communities.

Our Guiding Principles

• Support collaborative approaches to address unmet community needs
• Promote proven health care techniques and understanding
• Encourage innovative approaches to health care and understanding
• Identify and advocate for underserved and vulnerable populations

Wyoming County Health Grants

Our grants focus on programs and organizations that will improve the health and wellness of people in Wyoming County, PA and surrounding communities.

Our vision is to be recognized as a collaborative and important funding source for programs that provide for enhanced health -- and the understanding of health and wellness -- in our communities.

The Ernest Morgan Memorial Scholarship, managed by CommunityGiving, supports central Minnesota student athletes and leaders to pursue higher education outside their home states. This scholarship aims to expand students' horizons and experiences, with a total award of $5,000 available. Open to high school seniors from specific schools, applicants are encouraged to apply online and demonstrate their leadership or athletic skills. This initiative enhances educational opportunities and fosters personal growth among local youth.

The Great American Cleanup Grants, offered by Keep America Beautiful, aim to enhance community beautification and environmental efforts across the U.S. This initiative encourages KAB affiliates to remove litter, plant greenery, and restore public spaces, contributing to the larger goal of cleaning up 25 billion pieces of litter by 2026. With cash grants available, this program fosters collaboration among communities, promoting sustainable practices and a cleaner, greener future for all.

The Public School Facility Improvement Grant Program supports Pennsylvania's public school districts and area career and technical schools by funding facility improvement projects. Grants range from $500,000 to $5 million, covering essential upgrades such as roof repairs, HVAC systems, plumbing, and energy-saving initiatives. This program aims to create safer, more accessible learning environments, enhancing educational opportunities for all students in the Commonwealth.

The Pennsylvania Commission on Crime and Delinquency (PCCD) invites applications for funding under the Endowment Act, distributing $48 million from NCAA penalties to support child sexual abuse prevention and victim assistance. This funding specifically targets Multidisciplinary Investigative Teams (MDITs) to develop satellite Child Advocacy Centers (CAC) in counties lacking sufficient cases. The goal is to enhance support for child abuse victims and improve response capabilities across the Commonwealth.

The Extension Risk Management Education (ERME) Competitive Grants: Exploratory Projects aim to enhance agricultural producers' economic viability through innovative risk management education. Funded by the University of Delaware, these grants offer up to $10,000 for projects that address emerging risk topics or support producer workshops. With an 18-month duration from April 2026 to September 2027, this initiative encourages the development of new educational approaches to better serve the needs of farmers and ranchers.

The Area Development Grant Program, managed by the Appalachian Regional Commission (ARC), supports economic growth in Appalachia through investments in critical infrastructure and workforce development. Targeting 423 counties across 13 states, the program encourages local communities to collaborate with state governments to identify and implement impactful projects. Key focus areas include enhancing utilities, promoting entrepreneurship, and strengthening local leadership. This initiative aims to uplift the 26 million residents of Appalachia, fostering sustainable economic opportunities.

About PCORI

PCORI funds patient-centered comparative clinical effectiveness research (CER).

Our Mission

PCORI helps people make informed healthcare decisions, and improves healthcare delivery and outcomes, by producing and promoting high-integrity, evidence-based information that comes from research guided by patients, caregivers, and the broader healthcare community.

Broad Pragmatic Studies PCORI Funding

The Patient-Centered Outcomes Research Institute (PCORI) intends to issue a Broad Pragmatic Studies (BPS) PCORI Funding Announcement (PFA), seeking to fund patient-centered comparative clinical effectiveness research (CER) projects. 

Research Initiative Highlights

CER compares at least two available health treatments, services or care delivery strategies. PCORI seeks proposals that compare clinical interventions (e.g., pharmacological and nonpharmacological treatments, screening and diagnostic approaches) and healthcare delivery system interventions (e.g., workforce, technologies, healthcare service delivery designs) to evaluate potential benefits and harms of different treatment and care delivery options, thus generating evidence that empowers patients, caregivers and the broader healthcare community with information to make informed choices that reflect their needs and preferences.

Special Areas of Emphasis

For Cycle 2 2026, PCORI is particularly interested in submissions that address the following Special Areas of Emphasis (SAE) within the BPS funding opportunity. The purpose of identifying these SAEs is to encourage submissions to these areas, rather than limiting submissions to these topics. Applicants addressing one of the below SAEs should identify the area that is best associated with their research approach:  

• Addressing Obesity
• Diabetes Prevention, Care and Treatment
• Management of Urogynecological and Pelvic Pain
• Pain Management for Individuals Living With Sickle Cell Disease

In PCORI-funded research, patients and other research partners are expected to meaningfully contribute their lived experience or professional expertise to ensure studies are patient-centered, relevant and useful for healthcare decision making. Applicants must address PCORI’s Foundational Expectations for Partnerships in Research — an evidence-based framework supported by tools and resources to guide effective engagement strategies. Applicants are also strongly encouraged to consider the inclusion of a broad range of patient-centered burdens and economic outcomes. 

Broad Pragmatic Studies PFA: Category 1, Category 2 and Category 3 Study Specifications

PCORI will commit up to $120 million in direct costs through this funding opportunity. This funding opportunity contains three categories for funding:

• Category 1: Category 1 will support research projects with direct costs up to and including $5 million.

• Category 2: Category 2 will support research projects with direct costs greater than $5 million and up to a maximum of $12 million. Applications for funding under Category 2 will be required to provide additional information in the Letter of Intent (LOI) and application to justify the size and scope of the proposed research projects and to explain how additional funds are necessary with respect to the scale, scope and complexity of personnel and material resources needed to address the research question.

• Category 3: Category 3 will support research projects with direct costs up to $12 million that utilize PCORnet® to conduct observational studies and/or pragmatic trials that are national in scale. Category 3 PCORnet Studies® must include two or more Clinical Research Networks and share study progress, performance metrics and best practices with the network to promote continuous learning and improvement. PCORnet Studies® will leverage the PCORnet Common Data Model® as appropriate. Additional details about Category 3 can be found on the PCORI website.  

The Mellon Foundation's Economic Development Grant Program aims to address economic disparities in Pittsburgh and southwestern Pennsylvania by enhancing workforce skills and creating job opportunities. The program focuses on talent development, workforce systems, and community building, advocating for innovative education and training that aligns with future job markets. It seeks proposals that promote 21st-century skills, foster entrepreneurship, and support underrepresented groups, ultimately driving economic independence and community vitality.

The Alternative Fuels Incentive Grant Program is now accepting applications for the 2026 program year.

AFIG has approximately $5 million in funding available to school districts, municipalities, nonprofit organizations, and businesses in Pennsylvania that want to transition to cleaner fuel transportation. Applicants will be eligible for a maximum grant award across all applications of $500,000. Individual application awards are still capped at $300,000.

Supported alternative fuels include electricity, compressed natural gas, liquefied natural gas, propane, hydrogen, hythane, biodiesel, ethanol, methanol, and other advanced biofuels. Grant funding covers:

• Incremental costs related to retrofitting vehicles to operate on alternative fuels;
• Incremental costs to purchase alternative fuel vehicles;
• Cost to purchase and install the necessary fleet-refueling or home-refueling equipment for alternative fuel vehicles;
• Cost to perform research, training, development, and demonstration of new applications or next-phase technology related to alternative fuel vehicles.

The Norfolk Southern Trades on Track SkillPointe Scholarship offers $5,000 scholarships for students pursuing trades education related to the rail industry. Eligible candidates must be enrolled in a post-secondary institution and focused on railway-related trades. With over 1,000 scholarships funded and a mission to close the skills gap, this initiative empowers individuals towards high-demand careers without requiring a four-year degree, ultimately strengthening the workforce and economy.

The National Forest Foundation's Matching Awards Program connects communities to forests by funding stewardship activities that promote engagement with National Forests and nearby public lands. This program aims to create lasting impacts, ensuring that all communities can benefit from the rich resources of these natural areas. By supporting various projects, the program fosters a deeper relationship between people and the environment, ultimately enhancing conservation efforts and community well-being.