Best Operating Grants for Nonprofits in Pennsylvania

The Charles B. Degenstein Foundation, established in 1989, provides grants to 501(c)(3) organizations in the Sunbury, Pennsylvania area. It focuses on educational and healthcare services, regional needs, and projects of strategic interest. Larger grants are awarded based on alignment with the Foundation's goals. Multi-year requests are discouraged, and the Foundation does not cover all project costs. It values community support and additional funding sources for projects.

The Pittsburgh Foundation

Established in 1945, The Pittsburgh Foundation is one of the nation’s oldest community foundations and as of 2022 is the 18th largest of more than 750 similar foundations across the United States.

As a community foundation, its resources comprise endowment funds established by individuals, businesses and organizations with a passion for charitable giving and fulfilling the Foundation’s mission of improving quality of life for all in the region. The Foundation currently manages about 2,500 individual donor funds and, together with its supporting organizations and its affiliate, The Community Foundation of Westmoreland County, has assets of $1.386 billion (2022). Grantmaking benefits a broad spectrum of basic needs and development opportunities within Pittsburgh and beyond.

Scholarships

The Pittsburgh Foundation and The Community Foundation of Westmoreland County provide scholarship opportunities for local students to pursue their educational goals. Scholarships are available for graduating high school seniors, undergraduates, graduate, medical and professional school students who are attending community colleges, four-year universities and career/technical schools.

Frank A. Weidman Fund

The Frank A. Weidman Fund was established at The Pittsburgh Foundation to provide funds for graduates of Pittsburgh Public Schools to complete college and university studies in the arts and social sciences.

Award Type: Single-Year Award

The Somatic Mosaicism across Human Tissues (SMaHT) Program aims to enhance our understanding of biological processes driven by somatic mutations in human tissues through innovative technology development. Since its inception in 2023, the program has produced multi-omic datasets from human tissues representing all germ layers. The NIH is now advancing to Stage 2, focusing on collaborative efforts to refine and implement validated technologies for somatic mutation detection and functional interpretation, promoting rigorous and cost-effective methodologies.

The Field Initiated Projects Program (Development) aims to enhance the inclusion and self-sufficiency of individuals with disabilities through innovative research and development. This program supports the creation of tools, methods, and systems that assist people with disabilities, particularly those with significant support needs. With 16 grants available, the initiative will span 36 months, focusing on impactful projects that foster independence, employment, and community integration.

Our Consortium

ROAR (Rare Organic Acidemias Research) is a multi‑center study that brings together patients, families, clinicians, and researchers to better understand rare organic acidemias such as PA, MMA, GA‑1, IVA, and others. Our goal is to improve lifelong care and future treatment options for the rare disease community.

ROAR works in partnership with patient organizations, clinicians, and research networks to ensure that study findings are shared, accessible, and meaningful. Families play a central role in shaping our questions and informing our direction.

Rare Organic Acidemias Research (ROAR) Consortium Pilot and Feasibility Grants

The overall mission of the ROAR pilot & feasibility grant is to support small projects which advance diagnosis, enhance clinical trial readiness, and improve therapies and outcomes for individuals with organic acidemias. Potential pilot projects may include data-mining of existing data, genotype-phenotype correlations, observational studies, patient-reported outcomes assessments, focus groups with patients and advocacy groups, interventional clinical trials (with prior NIH approval), biomarker studies, ancillary studies to ROAR clinical projects, or other similar projects. Upon completion of funding, we expect that the data generated from ROAR pilot projects will be leveraged for larger grant applications and larger projects within and outside the consortium. Moreover, we expect that the data generated will inform the design of future clinical trials and clinical studies in organic acidemias and ultimately, will impact the lives of individuals with organic acidemias by improving the diagnosis, management, and treatment for these disorders. 

Annual funding of up to $40,000 (total cost, including indirect costs) is available to support one pilot project for a one-year period. The ROAR Consortium intends to fund at least 1 award this cycle starting on October 15, 2026.

The Robert C. Seamans, Jr. Fellowship in Science, Technology, and Public Policy at Harvard Kennedy School supports students excelling in research and management at the intersection of technology and public policy. This fellowship fosters future leadership in these critical areas, ensuring a commitment to addressing pressing public challenges. Applicants from diverse backgrounds are encouraged, as the program is designed to promote inclusivity and recognizes the importance of varied perspectives in policy-making.

The Professor Emeritus John Edward Lillich Endowed Scholarship Program, funded by the United Negro College Fund, aims to provide need-based scholarships to students majoring in engineering at HBCUs, with a preference for those attending North Carolina Agricultural and Technical State University (NCAT). This scholarship honors John Edward Lillich, a WWII veteran and advocate for women in engineering, supporting students in their pursuit of education and leadership roles.

The Science of Science: Discovery, Communication, and Impact (SoS:DCI) program fosters research that enhances the public value of scientific endeavors. It invites proposals that explore mechanisms of scientific discovery, improve understanding of communication outcomes, and assess societal benefits of science. Emphasizing interdisciplinary approaches, the program prioritizes proposals that broaden participation in science, engage diverse teams, and support America's leadership in global scientific innovation. The goal is to create impactful, evidence-based policies and advance the science of science.

The Powering Affordable Reliable Technology (PART) Energy Program, managed by the Rural Utilities Service, seeks Letters of Interest for loan applications to fund renewable energy generation and energy storage projects. With approximately $410 million available from the Inflation Reduction Act, the program offers up to 75% financing for project costs, along with potential loan forgiveness options. This initiative aims to enhance energy infrastructure in rural areas, promoting sustainable energy solutions.

William Wayne Justice Center for Public Interest Law - The University of Texas School of Law

The William Wayne Justice Center for Public Interest Law was created in 2004 when the law school joined with Judge William Wayne Justice’s former law clerks and many admirers to establish it in his honor. The Justice Center is a comprehensive resource for students, faculty, alumni, and the community.

Since its inception, the Justice Center has steadily expanded its programming and scope. Dedicated to promoting a culture and habit of pro bono service by all students, the Justice Center includes the school-wide Richard and Ginni Mithoff Pro Bono Program. We also regularly undertake special projects that bring together research and pro bono work on topics as varied as real estate titles in the wake of natural disasters, expunging criminal records, and supported decision-making by persons with disabilities.

Baron & Budd Public Interest Summer Fellowships

In the summer of 2026, the Baron & Budd Public Interest Summer Fellowships Program will provide up to 4 fellows with a $8,000 stipend to work for at least 10 weeks under the supervision of an attorney at a qualified sponsoring organization.

The fellowships are supported by generous funding from Baron & Budd, PC.

This named fellowship is awarded through the Summer Public Service Program.

In just one application, our Common Scholarship Application provides students access to more than 150 scholarship opportunities with awards ranging from $1,000 to more than $5,000. 

In 2025, San Diego Foundation awarded a record-breaking $5.5 million in scholarships to nearly 1,400 students.

William “Peasy” Johnson Scholarship

Plan to enroll full-time at an accredited four-year university, community college, or licensed career/technical school in the United States in fall.

The Public Humanities Projects program supports projects that bring the ideas and insights of the humanities to life for general audiences through in-person, hybrid, or virtual programming. Projects must engage humanities scholarship to analyze significant themes in disciplines such as history, literature, ethics, and art history.

The Otto & Aegun Hensens Educational Fund, established in 2018, supports Hawaii high school graduates pursuing degrees in medicine, science, technology, engineering, or mathematics. To qualify, applicants must be residents of Hawaii, maintain a GPA of 2.0 or higher, and demonstrate financial need. Preference is given to previous recipients and members of the Aiea Korean Methodist Church. This fund plays a vital role in fostering future leaders in STEM fields.

The CHEST 2025 Travel Grant aims to foster inclusivity in chest medicine by supporting diverse healthcare professionals. Recipients receive complimentary registration and $1,000 for attending the CHEST Annual Meeting in Chicago. Open to CHEST members from historically excluded backgrounds, the grant enhances professional growth and engagement in the field. With a focus on diversity and equity, the program also offers opportunities for mentorship, contributing to the development of future leaders in chest medicine.

The Postdoctoral Diversity Enrichment Grant Program, funded by the Burroughs Wellcome Fund, offers $60,000 over three years to support underrepresented postdoctoral fellows in the U.S. and Canada. This initiative aims to enhance their career development through mentorship and networking opportunities. Since its inception in 2013, the program has awarded over 150 fellowships, investing more than $9 million to promote diversity in biomedical research and foster an inclusive scientific community.

Native Forward awards are allocated based on the financial aid information provided by the institution’s Financial Aid Office. Awards can vary, ranging from $100 to $30,000 per academic year.

Native Forward Scholars Fund members of federally and state-recognized Tribes as well as first and second-generation descendants. However, Native Forward Scholars Fund scholarship opportunities have different Tribal eligibility requirements and can be determined by submitting a Tribal Eligibility Certificate.

PNM Pueblo Education Endowment Everett F. Chavez Scholarship

The PNM Everett F. Chavez Memorial Scholarship was established to honor the life and legacy of Everett F. Chavez. The purpose of the PNM Everett F. Chavez Memorial Scholarship is to provide financial assistance to eligible students from one of the nineteen Pueblo Nations of New Mexico who are pursuing an undergraduate or graduate degree in the field of engineering. This opportunity is a merit-based award.

About Us

The Arthur L. Carter Journalism Institute at NYU

We want to educate those who agree. Opportunities abound in the media world, but at NYU Journalism, the opportunity to do compelling work that informs, engages, and matters to the societies in which we live drives our faculty, motivates our students, and shapes our approach.

Those who find this their calling will discover encouragement, support, and an endless amount to learn at NYU. Our graduates are able to work anywhere their talents take them, and they do. Students come here not only to gain competence in the journalist’s craft but also the tools to make it better than it is. And those two things are the essence of what we teach.

Matthew Power Literary Reporting Award

Matthew Power was an award-winning journalist who reported empathetically on the human condition. He died in March 2014, while on assignment in Uganda.

About the Award

The Matthew Power Literary Reporting Award is a grant of $15,000 to support the work of a promising early-career nonfiction journalist on a story that uncovers truths about the human condition.

Offered for the first time in 2015, the Award has been endowed by individuals and organizations touched by the life and work of Matthew Power, a wide-roving and award-winning journalist who sought to live and share the experience of the individuals and places on which he was reporting. Power, a longtime friend of the Arthur L. Carter Journalism Institute, died in March 2014, while on assignment in Uganda.

The award proceeds from the recognition that many important stories need to be reported from afar, and that publications do not always have the resources to send a journalist where the story is. The money need not be used exclusively for travel, but we expect that most successful applications will include such expenses. A panel of NYU journalism professors, outside writers, and editors will review the proposals. Finalists will be asked to take part in an interview online.

The judges will be interested in perpetuating Power’s legacy, as his former editor Roger Hodge put it, of “strong, character-driven narratives with detailed scenes and lyrical description.” Power was always open to the absurdity that often attends politics and international affairs; he was always searching, as he put it, for “the human truth beneath the sorry facts.” Power’s ultimate ambition, he added, was literary beauty.

That said, judges will be looking for a journalist as singular in his or her own approach as Power was in his. In addition to longform print projects, we will consider audio projects involving substantial reporting and running over 20 minutes in length. The award will not fund proposals to report on armed conflicts where journalists are already imperiled, nor projects that are mainly investigatory. The winner will normally receive visiting scholar privileges at NYU, including library access.

Golden Garden Scholarship

The Golden Garden Scholarship supports Buckingham and Louisa highschool seniors who plan to attend a two‑year community college or a four‑year university as full‑time students. Established to support first‑generation college students—particularly students of color—with financial need, the award provides $2,500 per year, renewable for up to four years, and seeks candidates who demonstrate an interest in the Arts & Humanities, have a minimum 2.75 high‑school GPA, and a commitment to healthy lifestyle choices. Recipients must reside in Buckingham or Louisa County, remain enrolled full‑time throughout the scholarship term, and uphold good character and citizenship.

The Gene & Joan Witiak Fund Grant, established in 2014 by the Lehigh Valley Community Foundation, supports charitable organizations focused on environmental and sustainability programs. This area-of-interest fund aims to tackle pressing issues by pooling resources from like-minded donors to create a greater impact. Through a community committee's recommendations, grants are awarded to initiatives that align with these values, fostering collaborative efforts for a sustainable future.

In just one application, our Common Scholarship Application provides students access to more than 150 scholarship opportunities with awards ranging from $1,000 to more than $5,000.

In 2025, San Diego Foundation awarded a record-breaking $5.5 million in scholarships to nearly 1,400 students.

Rotary Club of San Diego Diana Venable Scholarship

Diana Venable was a successful San Diego entrepreneur who spent much of her adult life devoted to helping financially disadvantaged children and young adults achieve a sense of respect, responsibility, and academic achievement in order to overcome the repeated cycle of poverty. As a member of the Rotary Club of San Diego, Ms. Venable exemplified the Rotary Motto of “Service Above Self” by contributing her time, financial resources, leadership, and enthusiasm to the cause of helping others experience the fulfillment of a more rewarding life through personal and educational achievement. This Scholarship Fund is dedicated to carrying on a small portion of the legacy of Ms. Venable, who, unfortunately, died at an early age.

The purpose of the Diana Venable Scholarship Fund is to enable low to moderate-income students who have a record of academic achievement and personal growth, along with leadership potential for both professional careers and civic contributions, to attend a college program. The primary focus will be on students who have ties to Rotary School Programs at Hoover, San Diego High and Monarch or students who have past Rotary ties through the Club’s other school programs or Club members at large. Recipients will be chosen during the second semester of their junior year and must meet rigorous standards in their senior year including: academic performance, personal growth through extracurricular, community service, and other activities, financial need, a high degree of motivation, and excellent communication skills. Recipients are also expected to actively pursue other sources of financial aid. The Diana Venable Scholarship committee will select one recipient to receive $20,000 over 4-5 years.

This scholarship may be used for tuition, books, fees, room & board, and other educational expenses.

This scholarship may be renewable (depending upon available funds) for up to five consecutive years of undergraduate coursework provided the recipient maintains full-time enrollment, a minimum 2.0 GPA on a 4.0 scale, and good citizenship record.

• Average number of awards: 1-2
• Average amount of award: not to exceed $5000 annually

The Erie Community Foundation offers Community Impact (CI) Sponsorships aimed at supporting free community events that benefit marginalized groups. With a focus on education and multicultural values, these sponsorships typically do not exceed $2,500. Applications are accepted on a rolling basis until funds are exhausted, with specific review dates throughout the year. Organizations must have a DEI strategy and be located in or serve Erie County, PA to be eligible.

The Ethel Sergeant Clark Smith Memorial Fund Grant supports organizations in southeastern Pennsylvania, focusing on community needs in Delaware County. Grants are awarded in areas such as medical, educational, cultural, arts, and human services. Eligible organizations must be 501(c)(3) exempt and provide a complete project budget. Average grant sizes range from $5,000 to $25,000, with no multi-year funding allowed. The foundation emphasizes responsive grant-making to adapt to local needs.

In just one application, our Common Scholarship Application provides students access to more than 150 scholarship opportunities with awards ranging from $1,000 to more than $5,000.

In 2025, San Diego Foundation awarded a record-breaking $5.5 million in scholarships to nearly 1,400 students.

Wen Bo Wang Scholarship

Be graduating high school seniors and plan to enroll full-time at an accredited four-year university in the United States in fall.

The Ignite Leadership Program, organized by the Society of Women Engineers, empowers early-career women engineers to enhance their leadership skills. Participants will assess their strengths, identify growth opportunities, and create personalized leadership development plans. This virtual program runs from September to December 2025, featuring group discussions and peer coaching. Its goal is to broaden the leadership pipeline within SWE, preparing the next generation of women leaders in engineering and technology.

The Department of the Air Force is soliciting innovative research proposals for technologies that enhance multi-source data processing to improve Battlespace Awareness and automate decision-making processes. With a funding ceiling of approximately $99M and awards ranging from $3M to $35M, this opportunity is open to qualified offerors, including Federally Funded Research and Development Centers (FFRDCs). Note that foreign participation is not allowed in this BAA.

The Mildred Rowlett Scholarship, offered by the Central Kentucky Community Foundation, supports Hart County graduating seniors in their pursuit of higher education. To qualify, applicants must rank in the top 15% of their class and aim for a degree in mathematics or a related field. This scholarship exemplifies the foundation's commitment to enhancing community life through educational opportunities.

This funding opportunity announcement (FOA) invites applications for Animal and Biological Material Resource Centers (P40), aimed at enhancing biomedical research through providing essential resources such as laboratory animal colonies and informatics tools. The initiative supports both the continuation of existing resources and the development of new ones, emphasizing alignment with NIH Institutes and Centers. Applicants are encouraged to consult with NIH staff to ensure their proposals meet program priorities and competitiveness in the grant process.