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Best Quality of Life Grants in South Carolina

Find the perfect Quality of Life Grants in South Carolina on Instrumentl. 9,000+ Quality of Life Grants in South Carolina in the United States.

9,000+

Available grants

$2.62B

Total funding

$5K

Median grant

9,000+ grants
$2.62B total
$5K median

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9,451 Results based on applied filters

HIV Prevention and Alcohol (R61/R33 Clinical Trials Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The HIV Prevention and Alcohol R61/R33 funding opportunity aims to advance innovative HIV prevention strategies through a phased research approach. The R61 phase focuses on developing and pilot testing interventions, addressing key implementation questions for diverse populations. Following successful milestones, the R33 phase expands testing of these interventions and explores their effectiveness and sustainability, particularly in relation to alcohol use and related health issues.
Infectious & Parasitic Diseases HIV / AIDS Preventative Healthcare

15 and the Mahomies Foundation Grants

15 And The Mahomies Foundation
Private
United States
Up to US $15,000
The 15 and the Mahomies Foundation Grants aim to enhance the lives of children by supporting health, wellness, and community initiatives. This private foundation seeks to fund 501(c)(3) non-profit organizations, focusing on charitable causes. Grant requests are reviewed quarterly, and applicants must meet eligibility criteria. However, the foundation does not accept applications from individuals or for non-charitable items such as autographs or game tickets.
Children’s Health & Pediatrics Children’s Mental Health Children With Disabilities +4 more

Rheumatology Scholarship – Undergraduate Students and Post-Baccalaureate Training

Rheumatology Research Foundation
Private
United States
US $2,000
The Rheumatology Scholarship supports undergraduate and post-baccalaureate students in attending ACR Convergence 2025, a premier event for rheumatology. Awardees gain exposure to innovative research and networking opportunities, enhancing their understanding of rheumatic diseases. The scholarship includes $2,000 for travel expenses and complimentary registration, encouraging future professionals to explore careers in this essential field. This initiative aims to strengthen the rheumatology workforce, ensuring better care for patients with musculoskeletal diseases.
Musculoskeletal Diseases Immune System Diseases Arthritis +1 more

Medical and Graduate Student Preceptorship

Rheumatology Research Foundation
Private
United States
US $4,000
The Medical and Graduate Student Preceptorship provides a unique opportunity for students to engage in rheumatology through either clinical or research experiences lasting 4 to 8 weeks. Participants will observe practices in a shadowing role, gaining invaluable insights without direct patient management. The program supports students with financial awards of $2,000 or $4,000, depending on the duration of their preceptorship, and includes additional funds for travel expenses to attend professional conferences.
Musculoskeletal Diseases Immune System Diseases Arthritis +1 more

Sustainable Forests and Communities Grant

Weyerhaeuser Family Foundation
Private
United States
Up to US $50,000
The Sustainable Forests and Communities Grant aims to foster environmentally and economically sustainable forest communities in the U.S., particularly where the Weyerhaeuser Family has interests. It prioritizes projects enhancing the environment, economy, and community through sustainable practices. Eligible organizations must be 501(c)(3) tax-exempt entities operating in forested areas, focusing on integrated approaches that value forest ecosystem services. This initiative encourages local job creation, sustainable economic activities, and innovative partnerships to achieve sustainability goals.
Forestry Environmental Conservation Ecology +1 more

HEAL Initiative-Early-Stage Discovery of New Pain Targets Within the Understudied Druggable Proteome (R03 Clinical Trial Not Allowed) (357655)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $100,000
The HEAL Initiative aims to identify new druggable targets for pain within the understudied proteome. This funding opportunity invites applications for pilot projects that generate preliminary data and tools for exploring these targets. The initiative seeks to enhance research on understudied proteins related to pain management, providing essential funding for biochemical and biological work. This NOFO is part of the NIH's broader effort to develop novel medications that address various aspects of opioid addiction and its consequences.
Chronic / Acute Pain Anesthesia and Pain Medicine Drug Use Disorder +1 more

Ella B. Cleveland Trust Grant

Ella B. Cleveland Trust
Private
United States
Unspecified amount
The Ella B. Cleveland Trust Grant supports charitable medical research organizations focusing on leukemia, muscular dystrophy, and cerebral palsy. Established in memory of Ella B. Cleveland, the trust prioritizes 501(c)(3) entities and has no geographic limitations, though it often funds organizations in Georgia. Applications are accepted year-round, with an average grant size of $5,000, and total annual giving ranging from $10,000 to $15,000.
Leukemia Muscular Dystrophy Cerebral Palsy

Tick-Borne Disease Research Program Therapeutic/Diagnostic Research Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The FY26 Tick-Borne Disease Research Program (TBDRP) Therapeutic/Diagnostic Research Award aims to foster innovative therapeutic and diagnostic research for Lyme disease and other tick-borne conditions. This award supports early-stage drug discovery and evaluation studies, as well as novel diagnostic methods that can be seamlessly implemented in clinical environments, ultimately enhancing patient care and quality of life.
Acarology Lyme Disease

AAAAI Mentorship Award

American Academy of Allergy, Asthma & Immunology (AAAAI)
Association/Society
United States
Unspecified amount
The AAAAI Mentorship Award honors dedicated mentors who significantly impact the careers of trainees and colleagues in the field of allergy and immunology. By supporting and guiding more than one mentee, awardees embody the core values of the American Academy of Allergy, Asthma & Immunology. This prestigious recognition highlights the importance of mentorship in fostering professional growth and advancing the specialty, benefiting both individuals and the broader medical community.
Immune System Diseases Asthma Allergies & Allergic Diseases +1 more

Alpha Gamma Delta Foundation: Fighting Hunger Grants

Alpha Gamma Delta Foundation Inc
Private
Canada, United States
Up to US $10,000
The Alpha Gamma Delta Foundation provides grants aimed at combating hunger in the U.S. and Canada, focusing on direct food assistance, food rescue, and nutrition education. Eligible organizations can receive up to $10,000 in funding, with an average grant size of $5,000. Since its inception, the Foundation has awarded over $2 million to support local food programs, ensuring communities have access to essential resources and assistance for those in need.
Food Access & Hunger Food Security Food Delivery & Distribution Services +1 more

WaterSMART Cooperative Watershed Management Program

US Department of the Interior: Bureau of Reclamation (USBR)
Federal Government
American Samoa, Guam +4 more
US $50,000 - US $300,000
The WaterSMART Cooperative Watershed Management Program offers funding to eligible entities for developing local solutions to water management issues. This initiative supports watershed group development, restoration planning, and project design, promoting stakeholder cooperation and improving water reliability. It aligns with key priorities from the Trump administration, addressing complex water challenges and enhancing federal grant oversight. By facilitating these efforts, the program aims to stretch limited water resources and foster collaborative solutions among diverse stakeholders.
Habitat & Ecosystem Restoration Water Resource Management

AAAAI Travel Scholarship

American Academy of Allergy, Asthma & Immunology (AAAAI)
Association/Society
United States
Up to US $1,000
The AAAAI Travel Scholarship supports eligible professionals to attend the AAAAI Annual Meeting in Philadelphia from February 27 to March 2, 2026. This event features plenary sessions, workshops, and presentations on current research in allergy and immunology. The scholarship not only provides financial assistance but also fosters opportunities for networking and collaboration among attendees, enhancing their knowledge and experience in the field.
Immune System Diseases Asthma Allergies & Allergic Diseases +1 more

Easement Restoration and Stewardship

USDA: Natural Resources Conservation Service (NRCS)
Federal Government
American Samoa, Guam +4 more
US $250,000 - US $5,000,000
The Easement Restoration and Stewardship program, funded by the USDA NRCS, focuses on restoring and managing Wetland and Floodplain Easements. It includes developing restoration plans, conducting assessments, and implementing stewardship activities to enhance ecological health. Awardees will collaborate with NRCS personnel to ensure effective restoration design and maintenance strategies, fostering sustainable landscapes. This initiative addresses critical habitat conditions and promotes long-term environmental benefits for protected lands.
Habitat & Ecosystem Restoration Freshwater Conservation Land / Habitat Conservation +1 more

Thoma Foundation Special Project Funding Grant

Carl And Marilynn Thoma Foundation
Private
United States
Unspecified amount
The Carl and Marilynn Thoma Foundation offers Special Project Funding to support innovative initiatives in the arts, particularly in under-resourced areas. This grant encourages collaborative projects that enhance community engagement and education, focusing on art exhibitions and scholarships in the greater Texas Panhandle. By fostering leadership and creativity, the Foundation aims to empower individuals and organizations to make a lasting impact in the fields of art and art history.
Fine Art Visual Arts Art Education +7 more

Notice of Intent to Publish a Funding Opportunity Announcement for HIV Pediatric, Adolescent and Maternal Clinical Trials

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $30,000,000
The US Dept. of Health & Human Services, through the Eunice Kennedy Shriver National Institute of Child Health and Human Development, is set to announce a funding opportunity focused on HIV research for pediatric and maternal populations. This initiative aims to foster innovative clinical trials addressing critical research areas in HIV, inviting collaborations from experts in various fields. Applications are not currently solicited, but potential applicants are encouraged to prepare for this opportunity.
Infectious & Parasitic Diseases HIV / AIDS Chronic Illnesses

Arthur N. Rupe Foundation Grant

Arthur N Rupe Foundation
Private
United States
Unspecified amount
The Arthur N. Rupe Foundation Grant focuses on promoting positive social change through scholarly studies, education, and public debate. It supports projects related to caregiving, civil debate, and public policy, aiming to enhance the quality of life in America. The foundation prioritizes specific project funding over general operations and does not support individuals or capital campaigns. Grant inquiries are invited through a letter of inquiry process, ensuring alignment with its mission.
Home Health Care Public Policy Nursing +3 more

MPPEP Phase 3 Invasive Wild-Caught Catfish (363804)

Rural Business-Cooperative Service
Federal Government
American Samoa, Guam +4 more
US $50,000 - US $2,000,000
The MPPEP Phase 3 program aims to enhance processing capabilities for invasive, wild-caught catfish, benefiting both processors and fishers. By increasing processing capacity and volume, the initiative seeks to create fair wages and stable job opportunities, fostering economic growth in rural areas. This grant will support innovative strategies that ensure sustainable practices and elevate incomes within the community, thus contributing to the overall development of the meat and poultry sector.
Agriculture Economic Services & Development Food Security +3 more

Emergency/Medical Workers Behavioral Health Fund

Healthwell Foundation
Private
United States
Up to US $2,000
The Emergency/Medical Workers Behavioral Health Fund aims to support emergency workers facing trauma and anxiety due to their roles. Established by the HealthWell Foundation, it provides financial assistance for treatment-related costs, including copayments for prescription drugs, counseling, and transportation. In 2024, the Foundation awarded over $1.2 billion to underinsured patients, ensuring no one is denied essential healthcare due to financial barriers. This initiative helps address the critical mental health needs of those who serve on the front lines.
Crisis Intervention Emergency Medical Care & Services Public Transportation & Mass Transit Systems +4 more

Jeanette Zaichkin NRP Nursing Grant for Excellence and Innovation in NRP Education

American Academy Of Pediatrics
Private
Canada, United States
Up to US $10,000
The Jeanette Zaichkin NRP Nursing Grant for Excellence and Innovation in NRP Education supports nurses dedicated to enhancing neonatal resuscitation training. This grant, offered by the American Academy of Pediatrics, provides up to $10,000 for innovative projects addressing key gaps in transitional physiology and evidence-based practices. Eligible applicants must be current NRP Instructors and work in neonatal care settings. The initiative aims to empower nurses in teaching essential skills for successful newborn resuscitation.
Nursing Obstetrics & Neonatal Care Medical Education & Professional Training +1 more

Wildlife Annual Grants - Established Investigator ( Avian/Fish/Invertebrates)

Morris Animal Foundation
Private
Afghanistan, Algeria +166 more
Approximately US $100,000
Morris Animal Foundation invites Established Investigators to submit pre-proposals for research focused on reptile and amphibian health. This initiative emphasizes the importance of animal health and welfare while facilitating impactful conservation efforts. Proposals must demonstrate clear animal health needs, collaborative strategies, and potential benefits to wildlife populations. Funding for these projects is anticipated to average around $100,000 over a maximum duration of 36 months, fostering innovative solutions for pressing health challenges in these species.
Herpetology Wildlife Health

Wildlife Health (Reptile and Amphibian) - First Award

Morris Animal Foundation
Private
Afghanistan, Algeria +166 more
Up to US $120,000
The Morris Animal Foundation invites research pre-proposals for the Wildlife Health (Reptile and Amphibian) - First Award, aimed at enhancing the health and welfare of amphibians and reptiles. This initiative focuses on impactful research, particularly in chytrid disease. Eligible applicants include early career researchers with appropriate qualifications and a clear understanding of animal health challenges. Projects should demonstrate collaboration with relevant stakeholders and provide direct benefits to wildlife populations, emphasizing conservation through an animal health perspective.
Herpetology Wildlife Health

Spartanburg Regional Foundation Grant

The Spartanburg Regional Healthcare System Foundation
Private
Cherokee County, South Carolina, Greenville County, South Carolina +2 more
Unspecified amount
The Spartanburg Regional Foundation, established in 1991, plays a crucial role in enhancing community health in the Upstate of South Carolina. By supporting projects and initiatives, the Foundation has contributed over $100 million to healthcare efforts. It allocates funds to priority areas such as maternal health, behavioral health, and workforce development. The Foundation aims to empower change through innovative grantmaking, benefiting both Spartanburg Regional Healthcare System and community partners dedicated to improving health outcomes.
Maternal And Perinatal Health Workforce Preparation & Job Readiness Health Disparities & Social Determinants of Health +1 more

Board of Associates Centennial Pollinator Fellowship

Garden Club of America
Association/Society
United States
Approximately US $4,000
The Garden Club of America Board of Associates Centennial Pollinator Fellowship offers funding for research on pollinator decline, specifically targeting bees, bats, butterflies, and moths. This fellowship, established in 2013, supports graduate students in U.S. institutions with annual funding typically around $4,000. It aims to enhance knowledge in pollinator science while fostering a new generation of scientists dedicated to conservation. Recipients may reapply for additional funding in subsequent years.
Entomology Mammalogy Pollinator Conservation

Wildlife Health (Reptile and Amphibian) - Pilot Study Awards

Morris Animal Foundation
Private
Afghanistan, Algeria +166 more
Up to US $20,000
The Morris Animal Foundation is offering Pilot Study Awards focused on reptile and amphibian health and welfare, particularly for chytrid research. These awards aim to fund innovative, proof-of-concept studies that demonstrate a clear understanding of animal health issues and collaboration with stakeholders. Proposals must have a direct impact on wildlife populations and adhere to strict health study policies. The maximum funding is $20,000 for a duration of 12 months, ensuring significant contributions to wildlife health advancements.
Herpetology Wildlife Health

NIHCM: Journalism Grants

The National Institute for Health Care Management
Private
United States
Unspecified amount
The NIHCM Journalism Grants support projects that enhance health reporting and education, targeting critical issues such as healthcare affordability, pharmaceutical pricing, provider market dynamics, and chronic disease management. This initiative emphasizes the importance of informing policymakers and the public on how to improve healthcare quality and access in the U.S. Proposals may also explore the role of artificial intelligence in healthcare delivery. Applications are welcome from journalists, nonprofits, and universities.
Journalism Health Information Technology Health Policy & Advocacy +5 more

Longleaf Landscape Stewardship Fund Grant

National Fish and Wildlife Foundation (NFWF)
Private
Acadia Parish, Louisiana, Adams County, Mississippi +389 more
US $250,000 - US $3,000,000
The Longleaf Landscape Stewardship Fund Grant, managed by the National Fish and Wildlife Foundation (NFWF), provides funding for projects aimed at restoring and conserving longleaf pine and bottomland hardwood forests. With approximately $30 million available for 2024, grants range from $250,000 to $3,000,000. This initiative, supported by various federal and private entities, emphasizes the importance of ecological preservation and sustainable land management practices.
Forestry Habitat & Ecosystem Restoration

J.R. Simplot Company Foundation Grant

J R Simplot Company Foundation Inc
Private
Arkansas, California +8 more
Unspecified amount
The J.R. Simplot Company Foundation Grant supports U.S. non-profit organizations focused on art, education, youth, community, and global food and agriculture. Established in 1929, the foundation is committed to enhancing community welfare through creative cultural endeavors, educational initiatives, health services, and youth programs. Applications are reviewed quarterly, ensuring a timely response to organizations dedicated to making a positive impact in their communities.
Performing Arts Visual Arts Education - Higher Education +5 more

Quality of Life Grants in South Carolina Highlights

Looking for quality of life grants in South Carolina?


Read more about each grant below or start your 14-day free trial to see all quality of life grants in South Carolina recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Quality of Life Grants in South Carolina

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Quality of Life Grants in South Carolina grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

53 Quality of Life Grants in South Carolina over $25K in average grant size

40 Quality of Life Grants in South Carolina over $50K in average grant size

32 Quality of Life Grants in South Carolina supporting general operating expenses

100+ Quality of Life Grants in South Carolina supporting programs / projects

2,000+ Grants on Instrumentl focused on Art & Culture

3,000+ Grants on Instrumentl focused on Education

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Quality of Life grants in South Carolina?

Most grants are due in the first quarter.

Q1
28.9%
Q2
25.2%
Q3
24.8%
Q4
21.1%

Typical Funding Amounts

What's the typical grant amount funded for Quality of Life Grants in South Carolina?

Grants are most commonly $15,000.

$500 $500 Min.
$15,000 $15 K Median
$535,356 $535.4 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for South Carolina?

Grants are most commonly $74,506.

$74,506

Total Number of Grants

What's the total number of grants in Quality of Life Grants in South Carolina year over year?

In 2024, funders in South Carolina awarded a total of 24,410 grants.

2022 21,855

2023 21,722

2024 24,410

Top Grant Focus Areas

Among all the Quality of Life Grants in South Carolina given out in South Carolina, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Quality of Life Grants in South Carolina changing over time?

Funding has increased by 22.06%.

2022 $1,534,818,247

2023 $1,485,349,233
-3.22%

2024 $1,813,067,383
22.06%

South Carolina Counties That Receive the Most Funding

How does grant funding vary by county?

Greenville County, Richland County, and Charleston County receive the most funding.

County Total Grant Funding in 2024
Greenville County $580,646,902
Richland County $413,417,941
Charleston County $355,724,083
Spartanburg County $325,246,878
Pickens County $159,596,081

Related Grants in South Carolina

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