Best Greenville Grants for Nonprofits in South Carolina

The Jean Griswold Foundation

The Jean Griswold Foundation (JGF) is a non-profit organization dedicated to supporting Caregivers through educational opportunities and scholarships. 

Our Mission

The mission of the Jean Griswold Foundation is to support Caregivers by providing educational scholarships* to enable them to further their training, enhance their careers, and better assist the clients they serve.

By offering educational scholarships*, our Foundation will not only make a positive impact on the Caregivers themselves, but also the clients they assist and the home healthcare agencies where they are employed, as well as help advance the overarching home-care industry.

Scholarships will be paid directly to the federally accredited educational institutions of the winning Scholars’ choosing.

Empowering Caregivers Through Education

The Jean Griswold Foundation Scholarship Program awards scholarships to deserving Caregivers who wish to further their education in a care-related field. Applicants do not have to be associated with Griswold in any way, and the funds will be paid directly to the institution where the caregiver will be receiving education.  

Our Winter 2026 Scholarship Application period is now open! Applications will be accepted until 11:59pm ET August 31, 2026. Join our email list to get the first notice of all Scholarship happenings.  

Where would we be without Caregivers? 

Their selflessness is astounding, yet they are often overlooked and underappreciated. 

The Jean Griswold Foundation is dedicated to supporting Caregivers, the backbone of the care industry. We provide educational scholarships so Care Professionals can further their training, enhance their skills, elevate their careers, and better assist the people they serve.

Greenville, South Carolina 501(c)(3) nonprofits seeking more than US $20,000 for capital or other mission-aligned projects can apply for the F. W. Symmes Foundation Grant. Funding supports programs benefiting Greenville County residents across arts, education, health, human services, environment, religion, and public benefit, with priority given to capital projects and sustainable initiatives.

New Leaf Fund - Summer Cycle

Community Foundation of Greenville administers grants to preserve parks, open spaces, and historical and cultural assets through the New Leaf Fund.

The New Leaf Fund was established in 2025 by a Greenville native with a passion for conservation.

The Foundation encourages grant requests that include the protection of land and waterfront areas, increased tree cover and access to green spaces, and the protection and restoration of historical properties, in the City of Greenville, in Greenville County, and, to a lesser degree, in the Upstate.

Additional Information

• Awards typically range from $20,000 to $100,000
• Applicants may apply for more than one grant annually
• Funding opportunities may include
• Projects including acquisition, development, preservation, or restoration of land
• Projects including acquisition, development, preservation, or restoration of historical and cultural assets
• Planning, survey, appraisal or design fees for implementing such projects

The TD Bank Community Sponsorships Program, supported by the TD Charitable Foundation, provides funding for events and activities that positively impact communities from Maine to Florida. This initiative aims to enhance community awareness and foster partnerships among diverse groups, promoting economic development, cultural enrichment, and social responsibility. Organizations can apply for funding to support community-oriented programs, with applications reviewed quarterly. It's essential to submit applications at least 90 days before the event deadlines.

The Robert B. and Ruth K. Lee Foundation Grant aims to enhance the quality of life in Greenville County, South Carolina. Established in 2000, the foundation supports diverse areas including arts, education, health, and human services. With no geographic limitations, it primarily funds programs benefiting the local community. Grants typically range from $2,000 to $5,000, emphasizing initiatives for the elderly, children’s programs in the arts, and literary projects. Organizations must be 501(c)(3) exempt to be eligible.

New Leaf Fund - Spring Cycle

The New Leaf Fund was established in 2025 by a Greenville native with a passion for conservation.

The Foundation encourages grant requests that include the protection of land and waterfront areas, increased tree cover and access to green spaces, and the protection and restoration of historical properties, in the City of Greenville, in Greenville County, and, to a lesser degree, in the Upstate.

Additional Information

• Awards typically range from $20,000 to $100,000
• Applicants may apply for more than one grant annually

Funding opportunities may include

Funding opportunities may include

• Projects including acquisition, development, preservation, or restoration of land
• Projects including acquisition, development, preservation, or restoration of historical and cultural assets
• Planning, survey, appraisal or design fees for implementing such projects

The Hathaway Family Foundation Grant aims to enhance the lives of individuals in need within Greenville, South Carolina. This private foundation focuses on improving food security, access to quality healthcare, conservation efforts, and addressing homelessness. By supporting organizations that provide temporary shelters, mental health care, and food distribution, the foundation ensures targeted assistance for the most vulnerable populations. The foundation's commitment reflects a dedication to fostering community well-being and positive change.

Nonprofit 501(c)(3) organizations serving Greenville, South Carolina can seek funding for programs that advance economic mobility, education, housing, transportation, and employment. With a mission to remove systemic barriers, Hollingsworth Funds provides US $15,000 - US $500,000 for general operating, capital, or project support benefiting Greenville County residents, especially low-income Black and Hispanic/Latinx communities.

Greenville, South Carolina 501(c)(3) nonprofits and government units can access funding through the Community Foundation of Greenville for high-impact projects in arts, education, environment, health, and human services. Greenville Women Giving awards US $50,000 - US $100,000 grants annually for initiatives serving residents of Greenville County, South Carolina.

The Spartanburg Regional Foundation, established in 1991, plays a crucial role in enhancing community health in the Upstate of South Carolina. By supporting projects and initiatives, the Foundation has contributed over $100 million to healthcare efforts. It allocates funds to priority areas such as maternal health, behavioral health, and workforce development. The Foundation aims to empower change through innovative grantmaking, benefiting both Spartanburg Regional Healthcare System and community partners dedicated to improving health outcomes.

Nonprofit 501(c)(3) organizations with budgets under $1 million serving Greenville, South Carolina communities with a Truliant branch can seek project support for financial wellness, social mobility, and workforce education initiatives. Truliant Federal Credit Union supports efforts like financial literacy, food security, affordable housing, transportation access, and career skills development through its quarterly Community Giving program.

The Spinks Family Foundation offers small grants to support non-profit organizations dedicated to improving community life in South Carolina. Eligible organizations must be 501(c)(3) certified, with a focus on volunteer engagement and community services. Applications are accepted on a rolling basis and reviewed quarterly, providing essential funding for initiatives in education, health, and food security. This philanthropic effort aims to foster strong, healthy communities and enhance the well-being of residents.

The Spinks Family Foundation provides large grants of $10,000 and above annually to support non-profit organizations focused on education, food security, health, and mental health initiatives. Organizations must be 501(c)3 certified and demonstrate community impact with at least 500 volunteer hours. Applications are accepted from March 1 to March 30, and awards are announced by September 15. This initiative aims to empower nonprofits to effectively address pressing community needs.

The Prisma Health-Upstate Foundation Micro-Grant Program, established in 2023, aims to enhance the patient experience and quality of care by providing clinical care teams with resources. Individual awards can reach up to $5,000, with funds available to selected applicants in February, to be utilized by the end of the fiscal year. Award recipients are expected to report on the impact of their funding, contributing to a legacy of compassionate care in the Upstate community.

Nonprofit 501(c)(3) organizations serving underrepresented children, PreK–12 students, or families in Greenville, South Carolina may be eligible for community-focused funding that supports direct program needs. Focused on education, child wellbeing, and community-based family support, the ScanSource Charitable Foundation prioritizes impactful services and meaningful volunteer opportunities within its Greenville County footprint.

Nonprofit 501(c)(3) organizations, public schools, and qualified local governments can receive funding to provide job-related classes and courses for their employees, including one-day sessions and certification programs. Grants from TD Charitable Foundation help Greenville, South Carolina nonprofits and other TD Bank market-area organizations strengthen staff skills while serving low- to moderate-income and historically underserved communities in areas like financial literacy, housing, education, and business development.

The Barbara Stone Foundation

Barbara Stone served as a champion for individuals with disabilities and the Foundation strives to continue her legacy. The Barbara Stone Foundation is a 501 (C) 3 non-profit organization based in Greenville County, South Carolina.

Our primary focus is to influence community systems policies and culture to result in equitable opportunities for individuals with disabilities. We do this by identifying gaps in the system, investing in or creating our own innovative programs, leveraging partnerships in the community and through our signature initiative Greenville CAN. Greenville CAN is a multi-stakeholder collective impact coalition focused on creating systemic community change through specific community projects focused on people with disabilities. Through our multi-faceted approach we believe we can achieve our vision of a community where all people with disabilities flourish.

Barbara Stone Community Leadership Award

Barbara Stone was an instrumental leader in the Greenville community when it came to the services and rights of people with disabilities. Her decades-long mission made a profound impact on the quality of life of many people with disabilities in Greenville County. Like Barbara, there are many dedicated individuals in Greenville who still carry on her legacy of service and giving. It is with great pride that the Barbara Stone Foundation has created an annual Community Leadership Award to honor an individual who has shown the same commitment, initiative and spirit. If you know of an individual who you think embodies some of the same characteristics as Ms Stone, we invite you to nominate this person. 

Barbara Stone led efforts to unify community and government leaders to establish day program options for children with disabilities and employment workshops for adults. In 1968, she helped establish a day camp for children and adults with disabilities and special needs which has grown into a wonderful summer camp called Camp Spearhead. Because of her, seeds were planted to establish many services that still exist today. Barbara’s legacy and determination to support individuals’ lives is now carried on through the Foundation which bears her name.

About PLTW GatewayPLTW Gateway (6-8) opens paths that create meaningful futures. It connects students to careers in areas they can, and can't, imagine.3M has partnered with PLTW to ensure students and teachers have the tools, resources and knowledge they need to succeed in STEM. 3M inspires the next generation of science leaders through the following goals:

• Increasing STEM exposure in K-12 classrooms
• Supporting experiential learning opportunitiesEnhancing the quality of STEM teaching
• Providing professional development opportunities for students

Program Requirements:

• The purpose of this grant is to assist the grantee's implementation of the PLTW Gateway program.
• Grantee must offer at least one PLTW Gateway unit in the 2027-2028 academic year.
• Grantee may implement any PLTW Gateway unit of their choosing.

Grant Award and Distribution Schedule:

• Total Award: $10,000
  • 2027-2028: $10,000

The SC Christian Foundation offers Community Trust Grants designed to support Christian non-profit organizations that share the Gospel beyond the church walls. Eligible ministries must complete a Ministry Introduction Form for review. Grants are awarded annually, with proposals released in July and announcements made in October. This initiative aims to address the evolving needs of communities in South Carolina, particularly in Spartanburg, Greenville, York, Horry, and Georgetown Counties.

BASF Corporation, a leading chemical company based in Florham Park, New Jersey, is committed to charitable giving that aligns with its corporate social responsibility goals. The focus areas include science education, environmental sustainability, and health and safety. Donations are only made to eligible non-profit organizations under the U.S. Internal Revenue Code, ensuring that contributions support initiatives that enhance the quality of life in BASF communities and promote a sustainable future.

The PNC Foundation's Grow Up Great Grant is a significant initiative aimed at enhancing educational opportunities for children from birth to age 5. With a commitment of $500 million, this program focuses on improving school readiness through support in vocabulary development, social-emotional learning, and the arts. By partnering with community-based nonprofits, PNC aims to foster stronger, smarter, and healthier communities, ensuring a brighter future for the next generation.

Greenville, South Carolina 501(c)(3) nonprofits focused on economic mobility, workforce readiness, entrepreneurship, or affordable housing can access funding through Bank of America Charitable Foundation’s Neighborhood Builders Program. Selected organizations receive a two-year leadership development experience plus capacity-building support, if they meet revenue thresholds and other organizational readiness requirements in eligible markets.

The Lynn Thornhill Scholarship, managed by the Beckley Area Foundation, supports students at Furman University in their pursuit of higher education. This scholarship is part of a broader initiative to facilitate charitable giving and enhance educational opportunities in Southern West Virginia. By providing financial assistance, the foundation aims to inspire students to achieve their academic goals and contribute positively to their communities.

The W. W. Burgiss Charities Grant supports initiatives focused on religion, education, and assistance for the needy in Greenville County, South Carolina. Established by W. W. Burgiss in 1925, the foundation prioritizes capital needs and one-time special projects, aiming to create measurable impacts. Eligible organizations must be 501(c)(3) exempt and demonstrate financial sustainability. With an average grant size of $12,000, the foundation aims to uplift the sick and underprivileged, ensuring local community enhancement through targeted funding.

The Housing for Everyone Grant Competition, part of the 2026 Initiative, aims to support eviction prevention in low-to moderate-income communities. This 20th annual initiative recognizes the destabilizing impact of eviction and displacement on families, which leads to job loss, school disruptions, and health issues. By funding innovative organizations, the competition seeks to provide stability for renters, enabling them to stay in their homes and communities.

The Partnerships for Opportunity and Workforce and Economic Revitalization (POWER) Initiative aims to revitalize communities impacted by coal industry transitions. This initiative provides funding for projects that diversify local economies, enhance job training, and create new employment opportunities. By fostering collaboration among various stakeholders, the POWER Initiative supports strategic investments that align with regional economic development plans, ensuring a more resilient future for coal-affected areas.

The Educational Foundation of America (EFA) supports the Reproductive Health & Justice Grant Program to enhance access to abortion and contraception throughout the U.S., particularly in Appalachia, Alabama, and Florida. EFA funds innovative organizations that advocate for reproductive rights, provide direct support to abortion services, and leverage impact investing strategies. This commitment aims to ensure reproductive freedom, foster equity, and promote sustainability in underserved communities.