Best Greenville County Grants for Nonprofits in South Carolina

About PLTW EngineeringPLTW Engineering students adopt a problem-solving mindset, are engaged in compelling, real-world challenges that help them become better collaborators and thinkers, and are prepared with skills to step into any career path they take.3M has partnered with PLTW to ensure students and teachers have the tools, resources and knowledge they need to succeed in STEM. 3M inspires the next generation of science leaders through the following goals:

• Increasing STEM exposure in K-12 classrooms
• Supporting experiential learning opportunitiesEnhancing the quality of STEM teaching
• Providing professional development opportunities for students

Program Requirements:

• Grantee must use their grant funds to expand their existing PLTW Engineering program.
  • Example expansion activities include but are not limited to adding an additional PLTW Engineering course not previously offered,
  • and/or adding additional class periods of an existing PLTW Engineering courses previously offered,
  • and/or training additional teachers in PLTW Engineering courses for the 2027-2028 academic year. 

Grant Award and Distribution Schedule:

• Total Award: $10,000
  • 2027-2028: $10,000

The SC INBRE: Mentored Student Pilot Projects (MSP) program offers undergraduate and graduate students in South Carolina funding of $3,000 for one year to conduct small, well-defined research projects under faculty mentorship. This initiative supports career development and hands-on training in biomedical research, enhancing the research capacity of member institutions. Applications are encouraged from students who have not previously held an SIRP award, fostering diversity in research participation.

About PLTW Computer SciencePLTW Computer Science students are technology trailblazers who are empowered through transportable skills and prepared to start their career, whether that is in computer science or not.3M has partnered with PLTW to ensure students and teachers have the tools, resources and knowledge they need to succeed in STEM. 3M inspires the next generation of science leaders through the following goals:

• Increasing STEM exposure in K-12 classrooms
• Supporting experiential learning opportunities enhancing the quality of STEM teaching
• Providing professional development opportunities for students

Program Requirements:

• Grantee must use their grant funds to expand their existing PLTW Computer Science program.
  • Example expansion activities include but are not limited to adding an additional PLTW Computer Science  course not previously offered,
  • and/or adding additional class periods of an existing PLTW Computer Science courses previously offered,
  • and/or training additional teachers in PLTW Computer Science courses for the 2027-2028 academic year. 

Grant Award and Distribution Schedule:

• Total Award: $5,000
  • 2027-2028: $5,000

The SC Christian Foundation offers Community Trust Grants designed to support Christian non-profit organizations that share the Gospel beyond the church walls. Eligible ministries must complete a Ministry Introduction Form for review. Grants are awarded annually, with proposals released in July and announcements made in October. This initiative aims to address the evolving needs of communities in South Carolina, particularly in Spartanburg, Greenville, York, Horry, and Georgetown Counties.

The Saint-Gobain Corporation Foundation Direct Grants program provides support to non-profit organizations in focus areas including STEM education, sustainable construction, and workforce development. The foundation aims to foster community development and environmental stewardship. Eligible applicants include IRS-recognized 501(c)(3) organizations and accredited educational institutions in the U.S. The Foundation prioritizes partnerships that allow employee involvement and volunteer support, aiming to build meaningful relationships with grantees.

The Bank of America Charitable Foundation focuses on supporting organizations that empower communities through basic needs, income creation, and stable housing. By investing in health and job opportunities, they aim to enhance economic mobility for low- and moderate-income families. Their partnerships target vulnerable populations, ensuring equitable access to resources that foster community vitality and resilience. This initiative emphasizes the importance of stable housing as a foundation for personal and communal growth.

New Leaf Fund - Spring Cycle

The New Leaf Fund was established in 2025 by a Greenville native with a passion for conservation.

The Foundation encourages grant requests that include the protection of land and waterfront areas, increased tree cover and access to green spaces, and the protection and restoration of historical properties, in the City of Greenville, in Greenville County, and, to a lesser degree, in the Upstate.

Additional Information

• Awards typically range from $20,000 to $100,000
• Applicants may apply for more than one grant annually

Funding opportunities may include

Funding opportunities may include

• Projects including acquisition, development, preservation, or restoration of land
• Projects including acquisition, development, preservation, or restoration of historical and cultural assets
• Planning, survey, appraisal or design fees for implementing such projects

New Leaf Fund - Summer Cycle

Community Foundation of Greenville administers grants to preserve parks, open spaces, and historical and cultural assets through the New Leaf Fund.

The New Leaf Fund was established in 2025 by a Greenville native with a passion for conservation.

The Foundation encourages grant requests that include the protection of land and waterfront areas, increased tree cover and access to green spaces, and the protection and restoration of historical properties, in the City of Greenville, in Greenville County, and, to a lesser degree, in the Upstate.

Additional Information

• Awards typically range from $20,000 to $100,000
• Applicants may apply for more than one grant annually
• Funding opportunities may include
• Projects including acquisition, development, preservation, or restoration of land
• Projects including acquisition, development, preservation, or restoration of historical and cultural assets
• Planning, survey, appraisal or design fees for implementing such projects

The Educational Foundation of America (EFA) supports the Reproductive Health & Justice Grant Program to enhance access to abortion and contraception throughout the U.S., particularly in Appalachia, Alabama, and Florida. EFA funds innovative organizations that advocate for reproductive rights, provide direct support to abortion services, and leverage impact investing strategies. This commitment aims to ensure reproductive freedom, foster equity, and promote sustainability in underserved communities.

The W. W. Burgiss Charities Grant supports initiatives focused on religion, education, and assistance for the needy in Greenville County, South Carolina. Established by W. W. Burgiss in 1925, the foundation prioritizes capital needs and one-time special projects, aiming to create measurable impacts. Eligible organizations must be 501(c)(3) exempt and demonstrate financial sustainability. With an average grant size of $12,000, the foundation aims to uplift the sick and underprivileged, ensuring local community enhancement through targeted funding.

Truliant's Community Giving program supports nonprofit organizations that enhance local communities near Truliant branches. Focus areas include financial wellness, social mobility, and workforce education, specifically targeting initiatives that promote financial literacy, basic stability, and career development. Eligible organizations must be 501(c)(3) tax-exempt and have been operational for at least three years. The program seeks to empower individuals and families while fostering community growth and stability.

The Jean Griswold Foundation

The Jean Griswold Foundation (JGF) is a non-profit organization dedicated to supporting Caregivers through educational opportunities and scholarships. 

Our Mission

The mission of the Jean Griswold Foundation is to support Caregivers by providing educational scholarships* to enable them to further their training, enhance their careers, and better assist the clients they serve.

By offering educational scholarships*, our Foundation will not only make a positive impact on the Caregivers themselves, but also the clients they assist and the home healthcare agencies where they are employed, as well as help advance the overarching home-care industry.

Scholarships will be paid directly to the federally accredited educational institutions of the winning Scholars’ choosing.

Empowering Caregivers Through Education

The Jean Griswold Foundation Scholarship Program awards scholarships to deserving Caregivers who wish to further their education in a care-related field. Applicants do not have to be associated with Griswold in any way, and the funds will be paid directly to the institution where the caregiver will be receiving education.  

Our Winter 2026 Scholarship Application period is now open! Applications will be accepted until 11:59pm ET August 31, 2026. Join our email list to get the first notice of all Scholarship happenings.  

Where would we be without Caregivers? 

Their selflessness is astounding, yet they are often overlooked and underappreciated. 

The Jean Griswold Foundation is dedicated to supporting Caregivers, the backbone of the care industry. We provide educational scholarships so Care Professionals can further their training, enhance their skills, elevate their careers, and better assist the people they serve.

The Robert B. and Ruth K. Lee Foundation Grant aims to enhance the quality of life in Greenville County, South Carolina. Established in 2000, the foundation supports diverse areas including arts, education, health, and human services. With no geographic limitations, it primarily funds programs benefiting the local community. Grants typically range from $2,000 to $5,000, emphasizing initiatives for the elderly, children’s programs in the arts, and literary projects. Organizations must be 501(c)(3) exempt to be eligible.

The TD Bank Community Sponsorships Program, supported by the TD Charitable Foundation, provides funding for events and activities that positively impact communities from Maine to Florida. This initiative aims to enhance community awareness and foster partnerships among diverse groups, promoting economic development, cultural enrichment, and social responsibility. Organizations can apply for funding to support community-oriented programs, with applications reviewed quarterly. It's essential to submit applications at least 90 days before the event deadlines.

The Spinks Family Foundation offers small grants to support non-profit organizations dedicated to improving community life in South Carolina. Eligible organizations must be 501(c)(3) certified, with a focus on volunteer engagement and community services. Applications are accepted on a rolling basis and reviewed quarterly, providing essential funding for initiatives in education, health, and food security. This philanthropic effort aims to foster strong, healthy communities and enhance the well-being of residents.

The Metropolitan Arts Council (MAC) offers the Arts Organization Quarterly Project Grant Program, prioritizing projects that enhance community impact through arts. Funding up to $3,000 with a 2:1 match encourages initiatives supporting artists, promoting cultural tourism, and ensuring access to the arts for all. This grant facilitates economic growth and aims to attract new audiences to artistic programming, fostering a vibrant cultural landscape in Greenville.

The Partnerships for Opportunity and Workforce and Economic Revitalization (POWER) Initiative aims to revitalize communities impacted by coal industry transitions. This initiative provides funding for projects that diversify local economies, enhance job training, and create new employment opportunities. By fostering collaboration among various stakeholders, the POWER Initiative supports strategic investments that align with regional economic development plans, ensuring a more resilient future for coal-affected areas.

The Nonprofit Resource Training Grant offers up to $1,000 for tax-exempt organizations to send employees to essential training and conferences. This initiative supports community-based groups that serve low- to moderate-income populations and align with The Ready Commitment. By enhancing employee skills, the grant aims to strengthen nonprofits and their impact in the community, ensuring they provide valuable services effectively.

The ScanSource Charitable Foundation Grant focuses on supporting underrepresented children, PreK-12 education, and community-based family support. The foundation prioritizes nonprofit organizations that provide essential resources and services to help these children thrive. Additionally, it emphasizes the importance of meaningful volunteer opportunities, ensuring funds directly address community needs. Organizations must be IRS-recognized 501(c)(3) entities and operate within the ScanSource footprint to be eligible for funding.

BASF Corporation, a leading chemical company based in Florham Park, New Jersey, is committed to charitable giving that aligns with its corporate social responsibility goals. The focus areas include science education, environmental sustainability, and health and safety. Donations are only made to eligible non-profit organizations under the U.S. Internal Revenue Code, ensuring that contributions support initiatives that enhance the quality of life in BASF communities and promote a sustainable future.

The Brinker International Charitable Giving Program focuses on giving back to communities through support for kids, hunger, and education. Organizations eligible for funding must be 501c(3) non-profits and submit requests at least six weeks prior to events. The program does not support individuals, political or religious organizations, or explicit discrimination policies. Funding is provided through monetary donations or in-kind contributions like dining certificates.

About

Community Foundation of Greenville bridges philanthropy and purpose in Greenville County, helping people make their charitable giving simpler and more powerful for 70 years. We strategically match diverse needs and opportunities in Greenville County with philanthropic resources.

Vision:

Community Foundation of Greenville will be the leading catalyst for developing assets and unlocking potential to meet the needs of an inclusive and equitable community.

Mission:

Community Foundation of Greenville improves the lives of Greenville County residents through strategic philanthropy, community investment, and collaborative leadership.

Minority-led Nonprofit Grants

Community Foundation of Greenville strives to make our leadership and grantmaking reflect a commitment to diversity, equity, and inclusion. We hope to break down barriers that nonprofit leaders of color face in securing philanthropic funding by providing grants for operating or program support for their organizations.

About

Community Foundation of Greenville bridges philanthropy and purpose in Greenville County, helping people make their charitable giving simpler and more powerful for 70 years. We strategically match diverse needs and opportunities in Greenville County with philanthropic resources.

Vision:

Community Foundation of Greenville will be the leading catalyst for developing assets and unlocking potential to meet the needs of an inclusive and equitable community.

Mission:

Community Foundation of Greenville improves the lives of Greenville County residents through strategic philanthropy, community investment, and collaborative leadership.

New Leaf Fund

Community Foundation of Greenville administers grants to preserve parks, open spaces, and historical and cultural assets through the New Leaf Fund.

The New Leaf Fund was established in 2025 by a Greenville native with a passion for conservation.

Established 501c(3) organizations and local municipalities are invited by the New Leaf Fund Committee to apply online through Community Foundation’s website during the spring, summer, and/or winter grant cycles.

The Foundation encourages grant requests that include the protection of land and waterfront areas, increased tree cover and access to green spaces, and the protection and restoration of historical properties, in the City of Greenville, in Greenville County, and, to a lesser degree, in the Upstate.

The Hathaway Family Foundation Grant aims to enhance the lives of individuals in need within Greenville, South Carolina. This private foundation focuses on improving food security, access to quality healthcare, conservation efforts, and addressing homelessness. By supporting organizations that provide temporary shelters, mental health care, and food distribution, the foundation ensures targeted assistance for the most vulnerable populations. The foundation's commitment reflects a dedication to fostering community well-being and positive change.

About PLTW GatewayPLTW Gateway (6-8) opens paths that create meaningful futures. It connects students to careers in areas they can, and can't, imagine.3M has partnered with PLTW to ensure students and teachers have the tools, resources and knowledge they need to succeed in STEM. 3M inspires the next generation of science leaders through the following goals:

• Increasing STEM exposure in K-12 classrooms
• Supporting experiential learning opportunitiesEnhancing the quality of STEM teaching
• Providing professional development opportunities for students

Program Requirements:

• The purpose of this grant is to assist the grantee's implementation of the PLTW Gateway program.
• Grantee must offer at least one PLTW Gateway unit in the 2027-2028 academic year.
• Grantee may implement any PLTW Gateway unit of their choosing.

Grant Award and Distribution Schedule:

• Total Award: $10,000
  • 2027-2028: $10,000

Project Lead the Way (PLTW) provides innovative, hands-on learning experiences for students in PreK-5, fostering confidence and career readiness. With support from 3M, PLTW Launch aims to enhance STEM education by increasing exposure, supporting experiential learning, and improving teaching quality. This partnership ensures that students and teachers have the necessary tools and resources to thrive in a rapidly evolving world, empowering the next generation of leaders in science and technology.

The Housing for Everyone Grant Competition, part of the 2026 Initiative, aims to support eviction prevention in low-to moderate-income communities. This 20th annual initiative recognizes the destabilizing impact of eviction and displacement on families, which leads to job loss, school disruptions, and health issues. By funding innovative organizations, the competition seeks to provide stability for renters, enabling them to stay in their homes and communities.