Best Greenville County Grants for Nonprofits in South Carolina

The Lynn Thornhill Scholarship, managed by the Beckley Area Foundation, supports students at Furman University in their pursuit of higher education. This scholarship is part of a broader initiative to facilitate charitable giving and enhance educational opportunities in Southern West Virginia. By providing financial assistance, the foundation aims to inspire students to achieve their academic goals and contribute positively to their communities.

The Spinks Family Foundation provides large grants of $10,000 and above annually to support non-profit organizations focused on education, food security, health, and mental health initiatives. Organizations must be 501(c)3 certified and demonstrate community impact with at least 500 volunteer hours. Applications are accepted from March 1 to March 30, and awards are announced by September 15. This initiative aims to empower nonprofits to effectively address pressing community needs.

The Spinks Family Foundation offers small grants to support non-profit organizations dedicated to improving community life in South Carolina. Eligible organizations must be 501(c)(3) certified, with a focus on volunteer engagement and community services. Applications are accepted on a rolling basis and reviewed quarterly, providing essential funding for initiatives in education, health, and food security. This philanthropic effort aims to foster strong, healthy communities and enhance the well-being of residents.

New Leaf Fund - Spring Cycle

The New Leaf Fund was established in 2025 by a Greenville native with a passion for conservation.

The Foundation encourages grant requests that include the protection of land and waterfront areas, increased tree cover and access to green spaces, and the protection and restoration of historical properties, in the City of Greenville, in Greenville County, and, to a lesser degree, in the Upstate.

Additional Information

• Awards typically range from $20,000 to $100,000
• Applicants may apply for more than one grant annually

Funding opportunities may include

Funding opportunities may include

• Projects including acquisition, development, preservation, or restoration of land
• Projects including acquisition, development, preservation, or restoration of historical and cultural assets
• Planning, survey, appraisal or design fees for implementing such projects

New Leaf Fund - Summer Cycle

Community Foundation of Greenville administers grants to preserve parks, open spaces, and historical and cultural assets through the New Leaf Fund.

The New Leaf Fund was established in 2025 by a Greenville native with a passion for conservation.

The Foundation encourages grant requests that include the protection of land and waterfront areas, increased tree cover and access to green spaces, and the protection and restoration of historical properties, in the City of Greenville, in Greenville County, and, to a lesser degree, in the Upstate.

Additional Information

• Awards typically range from $20,000 to $100,000
• Applicants may apply for more than one grant annually
• Funding opportunities may include
• Projects including acquisition, development, preservation, or restoration of land
• Projects including acquisition, development, preservation, or restoration of historical and cultural assets
• Planning, survey, appraisal or design fees for implementing such projects

Indigo Hope Foundation: Addiction Recovery Programs Grant

Funding programs that offer treatment, counseling, recovery support services, and harm reduction for individuals battling addiction.

Key Focus Areas:

• Treatment Services
• Recovery Support
• Harm Reduction
• Family Programs

Example Programs We Fund:

• Outpatient counseling programs
• Peer recovery support
• Addiction Recovery Residential Programs
• Family therapy services

Indigo Hope Foundation: At-Risk Youth Development Grant

Empowering programs that provide mentorship, education, life skills training, and opportunities for young people facing challenges.

Key Focus Areas:

• Mentorship Programs
• Educational Support
• Life Skills Training
• Career Development

Example Programs We Fund:

• After-school tutoring and mentorship
• Job readiness training
• Leadership development

Indigo Hope Foundation: First Responder Wellness Grant

Supporting programs that provide mental health resources, training, family support, and wellness services for our first responders.

Key Focus Areas:

• Mental Health Support
• Family Services
• Training Programs
• Peer Support

Example Programs We Fund:

• Critical incident stress management
• Family counseling services
• Peer support programs
• Wellness and resilience training

Indigo Hope Foundation: Veterans Support Services Grant

Assisting organizations that serve our veterans with housing, healthcare, job training, mental health services, and family support.

Key Focus Areas:

• Housing Assistance
• Mental Health Services
• Job Training
• Family Support

Example Programs We Fund:

• PTSD counseling services including canine training programs
• Job placement programs
• Emergency housing assistance
• Veterans court support

The Neighborhood Builders Program, supported by Bank of America, empowers 501(c)(3) nonprofits through a two-year leadership development initiative. Participants receive funding, training, and networking opportunities to enhance their impact in communities. Since its inception, the program has invested over $346 million, training more than 4,000 leaders. The initiative focuses on advancing social mobility and economic opportunities, ensuring affordable housing, and fostering resilient communities. This program is vital for nonprofits aiming to strengthen their leadership and community engagement.

The TD Bank Community Sponsorships Program, supported by the TD Charitable Foundation, provides funding for events and activities that positively impact communities from Maine to Florida. This initiative aims to enhance community awareness and foster partnerships among diverse groups, promoting economic development, cultural enrichment, and social responsibility. Organizations can apply for funding to support community-oriented programs, with applications reviewed quarterly. It's essential to submit applications at least 90 days before the event deadlines.

The Brinker International Charitable Giving Program focuses on giving back to communities through support for kids, hunger, and education. Organizations eligible for funding must be 501c(3) non-profits and submit requests at least six weeks prior to events. The program does not support individuals, political or religious organizations, or explicit discrimination policies. Funding is provided through monetary donations or in-kind contributions like dining certificates.

The ScanSource Charitable Foundation Grant focuses on supporting underrepresented children, PreK-12 education, and community-based family support. The foundation prioritizes nonprofit organizations that provide essential resources and services to help these children thrive. Additionally, it emphasizes the importance of meaningful volunteer opportunities, ensuring funds directly address community needs. Organizations must be IRS-recognized 501(c)(3) entities and operate within the ScanSource footprint to be eligible for funding.

The Bank of America Charitable Foundation focuses on supporting organizations that empower communities through basic needs, income creation, and stable housing. By investing in health and job opportunities, they aim to enhance economic mobility for low- and moderate-income families. Their partnerships target vulnerable populations, ensuring equitable access to resources that foster community vitality and resilience. This initiative emphasizes the importance of stable housing as a foundation for personal and communal growth.

The Robert B. and Ruth K. Lee Foundation Grant aims to enhance the quality of life in Greenville County, South Carolina. Established in 2000, the foundation supports diverse areas including arts, education, health, and human services. With no geographic limitations, it primarily funds programs benefiting the local community. Grants typically range from $2,000 to $5,000, emphasizing initiatives for the elderly, children’s programs in the arts, and literary projects. Organizations must be 501(c)(3) exempt to be eligible.

The SC INBRE: Mentored Student Pilot Projects (MSP) program offers undergraduate and graduate students in South Carolina funding of $3,000 for one year to conduct small, well-defined research projects under faculty mentorship. This initiative supports career development and hands-on training in biomedical research, enhancing the research capacity of member institutions. Applications are encouraged from students who have not previously held an SIRP award, fostering diversity in research participation.

Spectrum Digital Education Grants support nonprofit organizations in educating communities about broadband benefits and usage. These grants aim to bridge the digital divide, particularly for seniors and those with disabilities or ethnically diverse backgrounds. Applicants must demonstrate community partnership, address specific needs, and provide measurable impact metrics. With a focus on financial feasibility and meaningful outcomes, this initiative ensures that underrepresented urban and rural communities gain access to essential digital resources, fostering long-term improvement in their lives.

The Bank of America Charitable Foundation focuses on improving economic mobility and social progress through partnerships with nonprofits. It prioritizes basic needs, income creation, stable housing, and community empowerment. By supporting vulnerable populations, the foundation aims to enable individuals to achieve their goals and contribute positively to their communities. The foundation emphasizes sustainable progress, ensuring that all community members have access to essential resources and opportunities for growth.

About

Community Foundation of Greenville bridges philanthropy and purpose in Greenville County, helping people make their charitable giving simpler and more powerful for 70 years. We strategically match diverse needs and opportunities in Greenville County with philanthropic resources.

Vision:

Community Foundation of Greenville will be the leading catalyst for developing assets and unlocking potential to meet the needs of an inclusive and equitable community.

Mission:

Community Foundation of Greenville improves the lives of Greenville County residents through strategic philanthropy, community investment, and collaborative leadership.

New Leaf Fund

Community Foundation of Greenville administers grants to preserve parks, open spaces, and historical and cultural assets through the New Leaf Fund.

The New Leaf Fund was established in 2025 by a Greenville native with a passion for conservation.

Established 501c(3) organizations and local municipalities are invited by the New Leaf Fund Committee to apply online through Community Foundation’s website during the spring, summer, and/or winter grant cycles.

The Foundation encourages grant requests that include the protection of land and waterfront areas, increased tree cover and access to green spaces, and the protection and restoration of historical properties, in the City of Greenville, in Greenville County, and, to a lesser degree, in the Upstate.

Truliant's Community Giving program supports nonprofit organizations that enhance local communities near Truliant branches. Focus areas include financial wellness, social mobility, and workforce education, specifically targeting initiatives that promote financial literacy, basic stability, and career development. Eligible organizations must be 501(c)(3) tax-exempt and have been operational for at least three years. The program seeks to empower individuals and families while fostering community growth and stability.

About

Community Foundation of Greenville bridges philanthropy and purpose in Greenville County, helping people make their charitable giving simpler and more powerful for 70 years. We strategically match diverse needs and opportunities in Greenville County with philanthropic resources.

Vision:

Community Foundation of Greenville will be the leading catalyst for developing assets and unlocking potential to meet the needs of an inclusive and equitable community.

Mission:

Community Foundation of Greenville improves the lives of Greenville County residents through strategic philanthropy, community investment, and collaborative leadership.

Minority-led Nonprofit Grants

Community Foundation of Greenville strives to make our leadership and grantmaking reflect a commitment to diversity, equity, and inclusion. We hope to break down barriers that nonprofit leaders of color face in securing philanthropic funding by providing grants for operating or program support for their organizations.

The PNC Foundation's Grow Up Great Grant is a significant initiative aimed at enhancing educational opportunities for children from birth to age 5. With a commitment of $500 million, this program focuses on improving school readiness through support in vocabulary development, social-emotional learning, and the arts. By partnering with community-based nonprofits, PNC aims to foster stronger, smarter, and healthier communities, ensuring a brighter future for the next generation.

The Metropolitan Arts Council (MAC) offers the Arts Organization Quarterly Project Grant Program, prioritizing projects that enhance community impact through arts. Funding up to $3,000 with a 2:1 match encourages initiatives supporting artists, promoting cultural tourism, and ensuring access to the arts for all. This grant facilitates economic growth and aims to attract new audiences to artistic programming, fostering a vibrant cultural landscape in Greenville.

ATI Physical Therapy is dedicated to enhancing community health and wellness through its sponsorship and donation initiatives. With a mission to exceed customer expectations, ATI actively engages in philanthropic efforts that improve lives and promote quality care beyond clinic walls. They encourage requests for support while emphasizing a review process that ensures timely responses. Partnering with local organizations, ATI aims to elevate awareness of health and wellness, impacting thousands of lives each year.

The Ferguson Cares Grant is an essential aspect of Ferguson's Sustainability strategy, focusing on social challenges and community wellbeing. This grant supports nonprofit organizations in the U.S. dedicated to affordable housing, skilled trades workforce development, clean water access, and enhancing local economic quality of life. Ferguson aims to create lasting partnerships that drive positive impact within their operational regions, reflecting their commitment to social responsibility and community support.

The Partnerships for Opportunity and Workforce and Economic Revitalization (POWER) Initiative aims to revitalize communities impacted by coal industry transitions. This initiative provides funding for projects that diversify local economies, enhance job training, and create new employment opportunities. By fostering collaboration among various stakeholders, the POWER Initiative supports strategic investments that align with regional economic development plans, ensuring a more resilient future for coal-affected areas.

Project Lead the Way inc.

School and district leaders need a solution that cultivates confidence and career readiness—and PLTW checks all the boxes. As a nonprofit organization founded by educators and driven by education leaders, we've spent more than 28 years equipping students with the technical knowledge, transferable skills, and career confidence they need to thrive—through programs that integrate real-world industry partnerships, best-in-class teacher training, and our proven activity-, project-, problem-based (APB) instructional model. At PLTW, we're on a mission to create a transformative learning environment and empower students to develop in-demand knowledge and skills necessary to thrive in an evolving world. 

PLTW Engineering

PLTW Engineering students adopt a problem-solving mindset, are engaged in compelling, real-world challenges that help them become better collaborators and thinkers, and are prepared with skills to step into any career path they take. Each PLTW Engineering course engages students in interdisciplinary activities like working with a client to design a home, programming electronic devices or robotic arms, or exploring algae as a biofuel source. These activities not only build knowledge and skills in engineering, but also empower students to develop essential skills such as problem solving, critical and creative thinking, communication, collaboration, and perseverance.

PLTW Engineering - New Program (3M) 

3M forms lasting partnerships with communities and provides resources to help them succeed and grow – ensuring a more interconnected and thriving world. 3M inspires the next generation of science leaders through the following goals:

• Increasing STEM exposure in K-12 classrooms
• Supporting experiential learning opportunities
• Enhancing the quality of STEM teaching
• Providing professional development opportunities for students

3M has partnered with PLTW to ensure students and teachers have the tools, resources and knowledge they need to succeed in STEM.