Best Grants for Nonprofits Serving Disabled in South Carolina

Grants from Costco Foundation help South Carolina 501(c)(3) nonprofits that support children, education, and health and human services. Organizations serving children with disabilities may be eligible if their programs fit these priorities and demonstrate community need, measurable outcomes, collaboration, and a broad base of financial support through a monetary-only request.

The DanPaul Foundation aims to enhance early childhood development by training teachers and parents, protecting children from abuse, and promoting social responsibility. They provide grants to non-profits for programs that focus on education, health, and welfare of youth. Key initiatives include scholarships, environmental education, and support for underprivileged children. Grant amounts range from a few hundred dollars to $15,000 annually, with a focus on impactful, community-driven projects.

The Draper Richards Kaplan Foundation provides grants to early-stage social entrepreneurs working on scalable solutions to pressing social and environmental issues. By supporting organizations with innovative approaches and proven impact, they aim to uplift underserved communities globally. The foundation offers operational support, funding of up to $300,000 over three years, and fosters a collaborative community among its portfolio organizations. They focus on candidates demonstrating measurable impact and sustainable growth potential.

The Hearst Foundation's Social Service Grant focuses on tackling chronic poverty by funding direct-service organizations that implement effective solutions for economic independence and family strengthening. With a mission to support diverse nonprofits in the U.S., the Foundation allocates approximately 15% of its total funding to social services, prioritizing scalable programs that serve significant populations. The minimum grant size is $100,000, and special consideration is given to organizations addressing affordable housing, domestic violence, and youth development.

Nonprofit organizations working in health, education, or community services in South Carolina can access funding through Labcorp Charitable Foundation to support food pantries, healthcare for underserved populations, STEM programs, and healthy lifestyle initiatives. U.S.-based 501(c)(3) organizations serving disabled individuals through these activities may be eligible to apply.

The Michael & Susan Dell Foundation provides grants to organizations focused on improving the lives of children in urban poverty in the U.S., India, and South Africa. They prioritize projects in education, health, and family economic stability. Grants typically do not exceed 25% of a project's budget or 10% of an organization's annual expenses. The foundation seeks to partner with organizations already making an impact, ensuring funding supports impactful social enterprises.

Roche Corporate Donations and Philanthropy (CDP) focuses on impactful projects that foster sustainable development, engage employees, and leverage Roche's expertise. Their philanthropic efforts prioritize humanitarian, educational, environmental, and cultural initiatives, aiming to build stronger communities and support innovative projects. Eligibility is limited to local organizations, while ineligible projects include those with political or religious ties. The foundation strives to create a positive societal impact through collaboration and strategic partnerships.

The Semnani Family Foundation, established in 1993, is dedicated to supporting marginalized communities worldwide through health, education, and disaster relief initiatives. Founded by Khosrow and Ghazaleh Semnani, it began by funding an orphanage in Romania. The foundation also operates locally, providing free healthcare through the Maliheh Free Clinic in Utah. Its commitment to human welfare drives impactful partnerships in countries such as Afghanistan, India, and South Africa, focusing on the most vulnerable populations.

Nonprofit 501(c)(3) organizations funding charitable, scientific, medical, or educational programs in South Carolina that use funds within the U.S. may be eligible for this support. With a mission to strengthen charitable, scientific, medical, and educational work, Sidney Stern Memorial Trust provides tax-exempt organizations with project or program funding that could benefit disability-related services.

The Bank of America Foundation Sponsorship Program aims to enhance economic mobility and social progress in low- and moderate-income communities through partnerships with nonprofit organizations. This initiative focuses on critical areas such as workforce education, basic needs like food and housing, and community development. The Foundation invested $350 million last year and encourages employee volunteerism and giving, supporting nonprofits in various sectors, including arts, culture, and diversity initiatives.

South Carolina nonprofits and public entities serving people with disabilities, health needs, or other human services can seek up to US $15,000 for programs in Aiken and Edgefield counties. Organizations working in areas like disability care, medical clinics, mental health, rehabilitation, or services for people in need apply through the Community Foundation for the Central Savannah River Area’s competitive Community Grants program.

Nonprofit arts organizations and public agencies in South Carolina and other South Arts region states can receive US $500 - US $2,500 to make arts programs more accessible for people with disabilities. South Arts supports costs like accessibility audits, assistive services, accessible materials, website improvements, and modest facility signage enhancements, with priority for BIPOC, LGBTQIA+, disability-led, rural, and first-time applicants.

South Carolina 501(c)(3) nonprofits with budgets under $1 million can access funding for humanitarian, child welfare, youth services, education, and basic human needs programs that support quality of life. Grants from Hansen Family Foundation, typically US $1,000 - US $10,000, may benefit organizations serving disabled children or adults within these focus areas.

South Carolina 501(c)(3) nonprofits serving people in need can access funding through Robinson Foundation for programs in areas like children and families, education, medical assistance, poverty relief, and disaster relief. Eligible organizations must serve the Southern region, be operating for more than three years, and seek single-year, non-capital support that shows tangible, meaningful impact.

Nonprofit 501(c)(3) organizations providing community services in South Carolina can seek philanthropic grants or event sponsorships to support key service and fundraising goals. With a mission to strengthen communities, Insperity provides eligible charities with financial, volunteer, or in-kind support when they engage Insperity employees, are clients, or serve communities where employees live and work.

The Dudley T. Dougherty Foundation Grant supports nonprofit charitable organizations recognized under section 501(c)(3) of the IRS Revenue Code. Established in 2002, the foundation aims to empower groups committed to positive change, fostering respect for life and the environment. Their vision emphasizes collaboration for a better future, encouraging applicants to embody these values in their initiatives. With a focus on impactful projects, this grant is an opportunity for organizations striving to make a critical difference in our world.

Nonprofit 501(c)(3) organizations, public schools, and libraries can seek unrestricted program or operating support for environmental, human services, and related work from the Lawrence Foundation; awards typically range from US $5,000 - US $10,000. With a mission to support environmental and human services causes, this private family foundation accepts applications nationwide, and South Carolina disability-service nonprofits may be eligible if their programs fit these priorities.

Nonprofit 501(c)(3) organizations and schools supporting disability care and services in South Carolina can apply for Honda USA Foundation’s Mobility Pillar Award, with grants of US $25,000 - US $100,000 for programmatic support. Grants fund education, awareness, and infrastructure programs like therapeutic or adaptive services, comprehensive care, and mobility modifications or assistive technology benefiting communities where Honda associates live and work.

Nonprofit community-based organizations, colleges, universities, and government units in South Carolina can receive up to US $15,000 from the South Carolina Arts Commission to run summer K-12 arts education projects. Funding can support workshops, camps, residencies, public art, performances, exhibitions, equipment, planning, or professional development, including programs serving disabled children and youth.

Ameriprise Community Grants focus on supporting nonprofits that enhance community vitality and meet basic needs. With over 120 years of commitment to philanthropy, Ameriprise Financial engages employees in volunteerism and grantmaking. Key giving areas include hunger relief, housing stability, and community development. Priority is given to organizations with active volunteer engagement from Ameriprise advisors and employees, creating a meaningful impact on financial independence and community resilience.

Nonprofit 501(c)(3) organizations serving residents of Charleston, Berkeley, or Dorchester counties can seek funding for programs tackling structural racism and economic inequality, including those impacting disabled people. Grants from Coastal Community Foundation help South Carolina community programs build or strengthen collaborative partnerships, with awards of approximately US $3,200 through the Lowcountry Unity Fund.

South Carolina nonprofits and government units improving arts accessibility for people with disabilities in South Carolina can access funding through the South Carolina Arts Commission, with awards up to US $2,500. Grants reimburse program and facility costs like assistive technologies, accessible materials, staff training, and capital improvements that remove barriers for disabled participants.

The O'Reilly Automotive Foundation Grant focuses on enhancing community welfare through philanthropic initiatives that support economic stability, workforce development, health services, and disaster relief. Established in 2020, the Foundation seeks to empower underrepresented individuals and organizations in the U.S. by addressing vital community needs. It particularly aims to provide assistance to nonprofits that foster positive change and improve quality of life for those in need, ensuring a lasting impact in local communities.

Nonprofit 501(c)(3) organizations providing community programs, including disability services, in Charleston County, South Carolina can receive up to US $50,000 for work that strengthens local communities, meets basic needs, or advances education and wellness. BECU Foundation’s People Helping People Awards require nomination by a BECU member and focus on impactful, non-discriminatory programs.

South Carolina nonprofits serving youth and families through education, housing, food security, or environmental programs can access funding through Chick Fil A Foundation’s True Inspiration Awards. U.S. 501(c)(3) organizations may receive US $30,000 - US $350,000 for initiatives such as youth development, hunger relief, family services, community gardens, or environmental stewardship that may include services for disabled children and adults.

Nonprofit 501(c)(3) organizations providing direct human services, basic needs, and social services in Georgetown County, South Carolina can seek funding for discrete program or small capital needs. Grants from Yawkey Foundation help cover timebound projects or equipment aligned with an organization’s mission, with awards up to US $100,000 for high-impact work serving vulnerable and underserved people.

Nonprofit organizations in the U.S., including those in South Carolina serving people with disabilities, can apply for Mutual of America Foundation’s Community Partnership Award to recognize exemplary cross-sector collaborations. This national competition honors partnerships that measurably improve communities, demonstrate strong social impact, and can be replicated or scaled to address significant social issues.