Best Spartanburg County Grants for Nonprofits in South Carolina

Indigo Hope Foundation provides Spartanburg County, South Carolina 501(c)(3) nonprofits with US $500 - US $100,000 to support first responder mental health, wellness, and family services. Eligible programs include counseling, peer support, critical incident stress management, and resilience or wellness training for first responders and their families in the Upstate SC area.

Nonprofit organizations in Spartanburg County, South Carolina supporting at-risk youth through mentorship, education, life skills, or career development programs can access funding through The Indigo Hope Foundation, with awards from US $500 - US $100,000. Grants may support after-school tutoring, job readiness training, and leadership development initiatives for young people facing challenges.

Nonprofit organizations providing addiction treatment, counseling, recovery support, or harm reduction services in Spartanburg County, South Carolina can apply for grants of US $500 - US $100,000. Grants from Indigo Hope Foundation help fund outpatient counseling, peer recovery support, residential recovery programs, and family therapy, supporting local 501(c)(3) efforts in addiction and substance use recovery.

Every Dream of Parenthood Deserves a Chance

Making dreams of parenthood a reality, one grant and one bundle of joy at a time.

Our Mission

The Samantha and Kyle Busch Bundle of Joy Fund is dedicated to advancing access to IVF care and coverage, increasing awareness and providing support so others don’t have to navigate infertility alone.

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Your Journey to Parenthood Begins Here

We distribute grant awards up to three times annually.

Please note that the number of grants and funding amounts fluctuate based on:

1) the unique needs of our applicants, and

2) the success of our fundraising efforts.

Our mission is to help as many people as possible.

The Partnerships for Opportunity and Workforce and Economic Revitalization (POWER) Initiative aims to revitalize communities impacted by coal industry transitions. This initiative provides funding for projects that diversify local economies, enhance job training, and create new employment opportunities. By fostering collaboration among various stakeholders, the POWER Initiative supports strategic investments that align with regional economic development plans, ensuring a more resilient future for coal-affected areas.

ATI Physical Therapy is dedicated to enhancing community health and wellness through its sponsorship and donation initiatives. With a mission to exceed customer expectations, ATI actively engages in philanthropic efforts that improve lives and promote quality care beyond clinic walls. They encourage requests for support while emphasizing a review process that ensures timely responses. Partnering with local organizations, ATI aims to elevate awareness of health and wellness, impacting thousands of lives each year.

The Indigo Hope Foundation offers grants to organizations in the Upstate of South Carolina, focusing on addiction, homelessness, at-risk youth, veterans, and first responders. They award between $250 and $100,000, prioritizing projects that demonstrate measurable results and address critical community needs. Eligible applicants must be 501(c)(3) tax-exempt or government units, with only one application allowed per grant period. The foundation emphasizes collaboration and favors faith-based organizations.

Place-based 501(c)(3) nonprofits in Spartanburg County, South Carolina can seek Catalytic Grants to strengthen internal operations, with awards up to US $20,000. Focused on nonprofit growth and development, Spartanburg County Foundation supports improvements in talent recruitment and retention, financial management and development, and marketing, communications, and fundraising capacity.

Nonprofit 501(c)(3) organizations addressing basic human needs, income creation, and economic mobility can use this funding for programs in eligible Bank of America markets, including Spartanburg County, South Carolina. Grants from Bank of America Charitable Foundation help support housing stability, food, health, job creation, and small business and community development in low- and moderate-income communities.

The Prisma Health-Upstate Foundation Micro-Grant Program, established in 2023, aims to enhance the patient experience and quality of care by providing clinical care teams with resources. Individual awards can reach up to $5,000, with funds available to selected applicants in February, to be utilized by the end of the fiscal year. Award recipients are expected to report on the impact of their funding, contributing to a legacy of compassionate care in the Upstate community.

The Spartanburg Regional Foundation, established in 1991, plays a crucial role in enhancing community health in the Upstate of South Carolina. By supporting projects and initiatives, the Foundation has contributed over $100 million to healthcare efforts. It allocates funds to priority areas such as maternal health, behavioral health, and workforce development. The Foundation aims to empower change through innovative grantmaking, benefiting both Spartanburg Regional Healthcare System and community partners dedicated to improving health outcomes.

Nonprofit and for-profit organizations hosting community-focused events or activities in Spartanburg County, South Carolina can access funding through the TD Bank Community Sponsorships Program to support positive local impact and visibility. Grants from TD Charitable Foundation may benefit groups that engage the public, offer networking opportunities, and support community well-being while partnering with the bank.

The Barbara Stone Foundation

Barbara Stone served as a champion for individuals with disabilities and the Foundation strives to continue her legacy. The Barbara Stone Foundation is a 501 (C) 3 non-profit organization based in Greenville County, South Carolina.

Our primary focus is to influence community systems policies and culture to result in equitable opportunities for individuals with disabilities. We do this by identifying gaps in the system, investing in or creating our own innovative programs, leveraging partnerships in the community and through our signature initiative Greenville CAN. Greenville CAN is a multi-stakeholder collective impact coalition focused on creating systemic community change through specific community projects focused on people with disabilities. Through our multi-faceted approach we believe we can achieve our vision of a community where all people with disabilities flourish.

Barbara Stone Foundation: Community Innovations Grant

The Barbara Stone Foundation is committed to empowering individuals with disabilities. One of the ways we do this is by investing in innovative programs and initiatives that address unmet needs and provide creative solutions for the disability community in the Upstate of South Carolina. Our Community Innovations Grant program prioritizes applications that propose groundbreaking approaches to bridging service gaps and fostering inclusion. Our hope is that creative individuals and organizations in our community’s amazing network of providers will develop new ways to ensure our community is place where individuals with disabilities flourish.

The Barbara Stone Foundation

Barbara Stone served as a champion for individuals with disabilities and the Foundation strives to continue her legacy. The Barbara Stone Foundation is a 501 (C) 3 non-profit organization based in Greenville County, South Carolina.

Our primary focus is to influence community systems policies and culture to result in equitable opportunities for individuals with disabilities. We do this by identifying gaps in the system, investing in or creating our own innovative programs, leveraging partnerships in the community and through our signature initiative Greenville CAN. Greenville CAN is a multi-stakeholder collective impact coalition focused on creating systemic community change through specific community projects focused on people with disabilities. Through our multi-faceted approach we believe we can achieve our vision of a community where all people with disabilities flourish.

Barbara Stone Community Leadership Award

Barbara Stone was an instrumental leader in the Greenville community when it came to the services and rights of people with disabilities. Her decades-long mission made a profound impact on the quality of life of many people with disabilities in Greenville County. Like Barbara, there are many dedicated individuals in Greenville who still carry on her legacy of service and giving. It is with great pride that the Barbara Stone Foundation has created an annual Community Leadership Award to honor an individual who has shown the same commitment, initiative and spirit. If you know of an individual who you think embodies some of the same characteristics as Ms Stone, we invite you to nominate this person. 

Barbara Stone led efforts to unify community and government leaders to establish day program options for children with disabilities and employment workshops for adults. In 1968, she helped establish a day camp for children and adults with disabilities and special needs which has grown into a wonderful summer camp called Camp Spearhead. Because of her, seeds were planted to establish many services that still exist today. Barbara’s legacy and determination to support individuals’ lives is now carried on through the Foundation which bears her name.

Undergraduate and graduate students conducting biomedical research at SC INBRE network institutions in Spartanburg County, South Carolina can receive up to US $3,000 for one-year, mentored pilot projects. South Carolina IDeA Network of Biomedical Research Excellence supports student-led work in areas like molecular biology, neuroscience, genetics, and related fields under faculty guidance.

The SC Christian Foundation offers Community Trust Grants designed to support Christian non-profit organizations that share the Gospel beyond the church walls. Eligible ministries must complete a Ministry Introduction Form for review. Grants are awarded annually, with proposals released in July and announcements made in October. This initiative aims to address the evolving needs of communities in South Carolina, particularly in Spartanburg, Greenville, York, Horry, and Georgetown Counties.

Certified classroom teachers and media specialists in Polk County and Landrum public schools seeking professional development or educational travel can receive US $2,000 - US $5,000 to enhance their classroom teaching. Polk County Community Foundation supports teacher development in Spartanburg County, South Carolina by funding conferences, educational travel, and other projects that directly improve instructional practice.

The Spinks Family Foundation offers small grants to support non-profit organizations dedicated to improving community life in South Carolina. Eligible organizations must be 501(c)(3) certified, with a focus on volunteer engagement and community services. Applications are accepted on a rolling basis and reviewed quarterly, providing essential funding for initiatives in education, health, and food security. This philanthropic effort aims to foster strong, healthy communities and enhance the well-being of residents.

The Spinks Family Foundation provides large grants of $10,000 and above annually to support non-profit organizations focused on education, food security, health, and mental health initiatives. Organizations must be 501(c)3 certified and demonstrate community impact with at least 500 volunteer hours. Applications are accepted from March 1 to March 30, and awards are announced by September 15. This initiative aims to empower nonprofits to effectively address pressing community needs.

The Neighborhood Builders Program, supported by Bank of America, empowers 501(c)(3) nonprofits through a two-year leadership development initiative. Participants receive funding, training, and networking opportunities to enhance their impact in communities. Since its inception, the program has invested over $346 million, training more than 4,000 leaders. The initiative focuses on advancing social mobility and economic opportunities, ensuring affordable housing, and fostering resilient communities. This program is vital for nonprofits aiming to strengthen their leadership and community engagement.

The Jean Griswold Foundation

The Jean Griswold Foundation (JGF) is a non-profit organization dedicated to supporting Caregivers through educational opportunities and scholarships. 

Our Mission

The mission of the Jean Griswold Foundation is to support Caregivers by providing educational scholarships* to enable them to further their training, enhance their careers, and better assist the clients they serve.

By offering educational scholarships*, our Foundation will not only make a positive impact on the Caregivers themselves, but also the clients they assist and the home healthcare agencies where they are employed, as well as help advance the overarching home-care industry.

Scholarships will be paid directly to the federally accredited educational institutions of the winning Scholars’ choosing.

Empowering Caregivers Through Education

The Jean Griswold Foundation Scholarship Program awards scholarships to deserving Caregivers who wish to further their education in a care-related field. Applicants do not have to be associated with Griswold in any way, and the funds will be paid directly to the institution where the caregiver will be receiving education.  

Our Winter 2026 Scholarship Application period is now open! Applications will be accepted until 11:59pm ET August 31, 2026. Join our email list to get the first notice of all Scholarship happenings.  

Where would we be without Caregivers? 

Their selflessness is astounding, yet they are often overlooked and underappreciated. 

The Jean Griswold Foundation is dedicated to supporting Caregivers, the backbone of the care industry. We provide educational scholarships so Care Professionals can further their training, enhance their skills, elevate their careers, and better assist the people they serve.

The Mary Black Foundation Grant offers financial support to 501(c)3 organizations in Spartanburg County, SC, focusing on enhancing early life experiences. It prioritizes initiatives that improve access to healthcare for women and children, affordable childcare, and mental health resources. The Foundation promotes equity and inclusion in its grantmaking, ensuring all individuals have opportunities to thrive. Organizations must first submit an inquiry form to be considered for funding.

Nonprofit housing and community organizations focused on eviction prevention and housing stability in low- to moderate-income communities, including Spartanburg County, South Carolina, can access funding through TD Charitable Foundation. The Housing for Everyone Competition awards US $1,000,000 - US $2,000,000 to innovative early-intervention programs that help renters avoid eviction and remain in their communities.

Nonprofit 501(c)(3) organizations in Spartanburg County, South Carolina that run digital literacy or broadband education programs for families or seniors can apply for US $2,500 - US $50,000 to expand their impact. Spectrum supports technology access and digital literacy initiatives in eligible Spectrum markets that partner with low-income or multicultural communities and can report clear participation metrics.

Nonprofit 501(c)(3) organizations, government units, congregations, and educational institutions in Spartanburg County, South Carolina can seek capital funding for facilities and equipment benefiting at-risk children and youth. The Longleaf Fund from Foundation for the Carolinas offers US $10,000 - US $150,000 for one-time projects like play spaces, recreation areas, education technology, and adaptive or assistive equipment.

Academy Sports + Outdoors, a leading sporting goods retailer, supports community initiatives by providing donations to registered 501(c)(3) organizations. Their focus is on promoting safety and responsibility in sports and outdoor activities. Proposals must foster community engagement and must not be affiliated with religious or political groups. Events should take place in areas with Academy stores, ensuring a positive local impact while encouraging active lifestyles and connection among community members.

The Brinker International Charitable Giving Program focuses on giving back to communities through support for kids, hunger, and education. Organizations eligible for funding must be 501c(3) non-profits and submit requests at least six weeks prior to events. The program does not support individuals, political or religious organizations, or explicit discrimination policies. Funding is provided through monetary donations or in-kind contributions like dining certificates.