Best Cherokee County Grants for Nonprofits in South Carolina

Indigo Hope Foundation: Veterans Support Services Grant

Assisting organizations that serve our veterans with housing, healthcare, job training, mental health services, and family support.

Key Focus Areas:

• Housing Assistance
• Mental Health Services
• Job Training
• Family Support

Example Programs We Fund:

• PTSD counseling services including canine training programs
• Job placement programs
• Emergency housing assistance
• Veterans court support

South Carolina Department of Commerce

From site selection to infrastructure improvement, we are here to help grow new and existing businesses.

SC Commerce promotes economic opportunity for individuals and businesses through initiatives like workforce training. As a national leader in foreign direct investment, the state extends its global reach with offices in Europe and Asia that help existing companies in developing export markets.

South Carolina Community Development Block Grant

The South Carolina Community Development Block Grant (“State CDBG Program”) is designed to aid units of general local government in improving economic opportunities and meeting community revitalization needs, particularly for persons of low- and moderate-income. The State CDBG Program has been funded through the State since 1982 by the U.S. Department of Housing and Urban Development (HUD) under the Housing and Community Development Act of 1974, as amended (Title I). 

CDBG Program Goals and Outcomes

The SC Department of Commerce seeks to improve the well-being of all South Carolinians in a manner that supports and enhances a high quality of life. The State CDBG Program supports the agency’s efforts to strengthen communities through revitalization and improvement of neighborhoods, public infrastructure, and the local economy. 

The three overarching goals of the HUD CDBG program are to provide decent housing, economic opportunities and a suitable living environment. Within the context of these goals, each project funded by the State must also meet one of three outcomes identified by HUD: affordability, accessibility, or sustainability. 

Local Match/Leveraging

CDBG projects are expected to leverage other public and private investments and serve as a catalyst for future development.

There must be a 10% match of the total CDBG request, unless otherwise approved, which can come from a variety of committed sources including other grants, loans, waiver of fees, public or private investments, and documented volunteer or in-kind contributions. Matching funds must be immediately available for the project at the time of application. 

Community Development Block Grant Categories

There are three broad grant program categories: Community Development, Business Development, and Regional Planning. The Community Development Program is further broken down into several subcategories to address infrastructure, community facilities, and local priorities.

Community Development Programs

Description

This program is designed to produce outcomes that improve citizens’ quality of life and create a competitive environment for jobs and investment by addressing priority community development needs. Activities should contribute to healthy, safe and sustainable neighborhoods and communities. These grants are designed to improve the quality of life for distressed and LMI communities. Community Development projects will compete within the following subcategories that have the same general submission requirements, except that the Ready to Go Program will not be funded in a competitive funding round.

Community Development Program Categories: Community Infrastructure; Community Enrichment; Local Priorities Program; and Ready to Go Program

Local Priorities Program

Outcome and Priorities

This program is designed to address unique local and regional needs and priorities for addressing those needs through community development, including projects that reflect priorities established in conjunction with the S.C. Department of Commerce Business Incentives & Community Development Division. Projects may reflect community development needs that are not typically funded through the other State CDBG programs and generally should not be funded by other HUD partner programs, such as HOME and NHTF (affordable housing), ESG (homelessness) or HOPWA (special needs). These funds will be used for alternative grant activities and partnerships that meet the community development needs of eligible municipalities. Local Priority projects could include historic preservation, innovation, energy conservation, parks, and trails/greenways. New or expanded public service activities are also eligible. Projects should leverage other funding or include local funding; impact identified needs and demonstrate strong community support while meeting a National Objective and all other requirements. 

South Carolina Department of Commerce

From site selection to infrastructure improvement, we are here to help grow new and existing businesses.

SC Commerce promotes economic opportunity for individuals and businesses through initiatives like workforce training. As a national leader in foreign direct investment, the state extends its global reach with offices in Europe and Asia that help existing companies in developing export markets.

South Carolina Community Development Block Grant

The South Carolina Community Development Block Grant (“State CDBG Program”) is designed to aid units of general local government in improving economic opportunities and meeting community revitalization needs, particularly for persons of low- and moderate-income. The State CDBG Program has been funded through the State since 1982 by the U.S. Department of Housing and Urban Development (HUD) under the Housing and Community Development Act of 1974, as amended (Title I). 

CDBG Program Goals and Outcomes

The SC Department of Commerce seeks to improve the well-being of all South Carolinians in a manner that supports and enhances a high quality of life. The State CDBG Program supports the agency’s efforts to strengthen communities through revitalization and improvement of neighborhoods, public infrastructure, and the local economy. 

The three overarching goals of the HUD CDBG program are to provide decent housing, economic opportunities and a suitable living environment. Within the context of these goals, each project funded by the State must also meet one of three outcomes identified by HUD: affordability, accessibility, or sustainability. 

Local Match/Leveraging

CDBG projects are expected to leverage other public and private investments and serve as a catalyst for future development.

There must be a 10% match of the total CDBG request, unless otherwise approved, which can come from a variety of committed sources including other grants, loans, waiver of fees, public or private investments, and documented volunteer or in-kind contributions. Matching funds must be immediately available for the project at the time of application. 

Community Development Block Grant Categories

There are three broad grant program categories: Community Development, Business Development, and Regional Planning. The Community Development Program is further broken down into several subcategories to address infrastructure, community facilities, and local priorities.

Community Development Programs

Description

This program is designed to produce outcomes that improve citizens’ quality of life and create a competitive environment for jobs and investment by addressing priority community development needs. Activities should contribute to healthy, safe and sustainable neighborhoods and communities. These grants are designed to improve the quality of life for distressed and LMI communities. Community Development projects will compete within the following subcategories that have the same general submission requirements, except that the Ready to Go Program will not be funded in a competitive funding round.

Community Development Program Categories: Community Infrastructure; Community Enrichment; Local Priorities Program; and Ready to Go Program

Community Enrichment Grants

Outcome and Priorities

This program is designed to fund public facilities, services and other activities that strengthen existing communities and support a high quality of life within the following state priority areas:

• Economic competitiveness and resiliency
• Education and workforce development
• Safe and healthy communities

Project investments should contribute to quality of life and the long-term vitality of communities. Activities must have the broad support of citizens and local businesses. Buildings and brownfield sites should be owned by the local government. Note that costs for operating or maintaining public facilities are not eligible for CDBG, so building projects must demonstrate financial viability. Equipment for public service activities must be for new or expanded services and generally associated with a significant capital investment in facilities. Only major pieces of equipment that have a durable life of five years will be considered for funding.

The Barbara Stone Foundation

Barbara Stone served as a champion for individuals with disabilities and the Foundation strives to continue her legacy. The Barbara Stone Foundation is a 501 (C) 3 non-profit organization based in Greenville County, South Carolina.

Our primary focus is to influence community systems policies and culture to result in equitable opportunities for individuals with disabilities. We do this by identifying gaps in the system, investing in or creating our own innovative programs, leveraging partnerships in the community and through our signature initiative Greenville CAN. Greenville CAN is a multi-stakeholder collective impact coalition focused on creating systemic community change through specific community projects focused on people with disabilities. Through our multi-faceted approach we believe we can achieve our vision of a community where all people with disabilities flourish.

Barbara Stone Foundation: Community Innovations Grant

The Barbara Stone Foundation is committed to empowering individuals with disabilities. One of the ways we do this is by investing in innovative programs and initiatives that address unmet needs and provide creative solutions for the disability community in the Upstate of South Carolina. Our Community Innovations Grant program prioritizes applications that propose groundbreaking approaches to bridging service gaps and fostering inclusion. Our hope is that creative individuals and organizations in our community’s amazing network of providers will develop new ways to ensure our community is place where individuals with disabilities flourish.

The Barbara Stone Foundation

Barbara Stone served as a champion for individuals with disabilities and the Foundation strives to continue her legacy. The Barbara Stone Foundation is a 501 (C) 3 non-profit organization based in Greenville County, South Carolina.

Our primary focus is to influence community systems policies and culture to result in equitable opportunities for individuals with disabilities. We do this by identifying gaps in the system, investing in or creating our own innovative programs, leveraging partnerships in the community and through our signature initiative Greenville CAN. Greenville CAN is a multi-stakeholder collective impact coalition focused on creating systemic community change through specific community projects focused on people with disabilities. Through our multi-faceted approach we believe we can achieve our vision of a community where all people with disabilities flourish.

Barbara Stone Community Leadership Award

Barbara Stone was an instrumental leader in the Greenville community when it came to the services and rights of people with disabilities. Her decades-long mission made a profound impact on the quality of life of many people with disabilities in Greenville County. Like Barbara, there are many dedicated individuals in Greenville who still carry on her legacy of service and giving. It is with great pride that the Barbara Stone Foundation has created an annual Community Leadership Award to honor an individual who has shown the same commitment, initiative and spirit. If you know of an individual who you think embodies some of the same characteristics as Ms Stone, we invite you to nominate this person. 

Barbara Stone led efforts to unify community and government leaders to establish day program options for children with disabilities and employment workshops for adults. In 1968, she helped establish a day camp for children and adults with disabilities and special needs which has grown into a wonderful summer camp called Camp Spearhead. Because of her, seeds were planted to establish many services that still exist today. Barbara’s legacy and determination to support individuals’ lives is now carried on through the Foundation which bears her name.

The Piedmont Natural Gas Company Grant Program, part of the Duke Energy Foundation, supports community vitality through grants of $20,000 or less. Focus areas include vibrant economies, climate resiliency, and promoting opportunity and inclusion. Eligible organizations must have tax-exempt status and serve communities without discrimination. The foundation prioritizes measurable community impact and does not fund certain entities, including for-profits and religious organizations. Applications are accepted year-round on a rolling basis.

The Truliant Mini Grants program offers $1,500 grants to 501(c)(3) nonprofits serving Truliant member communities. These grants support capacity building through staff training and development, along with materials for programs aligned with Truliant's focus areas: Social Mobility, Financial Wellness, and Workforce Education. Eligible organizations must have an operating budget under $500,000, be tax-exempt, and have been operating for at least three years, ensuring community engagement and sustainability.

South Carolina Department of Commerce

From site selection to infrastructure improvement, we are here to help grow new and existing businesses.

SC Commerce promotes economic opportunity for individuals and businesses through initiatives like workforce training. As a national leader in foreign direct investment, the state extends its global reach with offices in Europe and Asia that help existing companies in developing export markets.

South Carolina Community Development Block Grant

The South Carolina Community Development Block Grant (“State CDBG Program”) is designed to aid units of general local government in improving economic opportunities and meeting community revitalization needs, particularly for persons of low- and moderate-income. The State CDBG Program has been funded through the State since 1982 by the U.S. Department of Housing and Urban Development (HUD) under the Housing and Community Development Act of 1974, as amended (Title I). 

CDBG Program Goals and Outcomes

The SC Department of Commerce seeks to improve the well-being of all South Carolinians in a manner that supports and enhances a high quality of life. The State CDBG Program supports the agency’s efforts to strengthen communities through revitalization and improvement of neighborhoods, public infrastructure, and the local economy. 

The three overarching goals of the HUD CDBG program are to provide decent housing, economic opportunities and a suitable living environment. Within the context of these goals, each project funded by the State must also meet one of three outcomes identified by HUD: affordability, accessibility, or sustainability. 

Local Match/Leveraging

CDBG projects are expected to leverage other public and private investments and serve as a catalyst for future development.

There must be a 10% match of the total CDBG request, unless otherwise approved, which can come from a variety of committed sources including other grants, loans, waiver of fees, public or private investments, and documented volunteer or in-kind contributions. Matching funds must be immediately available for the project at the time of application. 

Community Development Block Grant Categories

There are three broad grant program categories: Community Development, Business Development, and Regional Planning. The Community Development Program is further broken down into several subcategories to address infrastructure, community facilities, and local priorities.

Community Development Programs

Description

This program is designed to produce outcomes that improve citizens’ quality of life and create a competitive environment for jobs and investment by addressing priority community development needs. Activities should contribute to healthy, safe and sustainable neighborhoods and communities. These grants are designed to improve the quality of life for distressed and LMI communities. Community Development projects will compete within the following subcategories that have the same general submission requirements, except that the Ready to Go Program will not be funded in a competitive funding round.

Community Development Program Categories: Community Infrastructure; Community Enrichment; Local Priorities Program; and Ready to Go Program

Community Infrastructure Grants

Outcome and Priorities

A Community Infrastructure application must contribute to creation of healthy and sustainable residential communities through water, sewer, roads, drainage or other activities that address one or more of the priorities listed in order of importance:

Significant improvements to existing infrastructure to address health concerns, meet required quality standards, ensure community sustainability or improve resiliency.

Projects that result in a more viable regional infrastructure solution or that provide new access to services near business centers where it is cost effective to address a documented health threat

Upgrades to infrastructure to address quality standards where there are only general health concerns or provide new services that are not near business centers when it is cost effective to address a documented health threat

The Neighborhood Builders Program, supported by Bank of America, empowers 501(c)(3) nonprofits through a two-year leadership development initiative. Participants receive funding, training, and networking opportunities to enhance their impact in communities. Since its inception, the program has invested over $346 million, training more than 4,000 leaders. The initiative focuses on advancing social mobility and economic opportunities, ensuring affordable housing, and fostering resilient communities. This program is vital for nonprofits aiming to strengthen their leadership and community engagement.

The Spinks Family Foundation provides large grants of $10,000 and above annually to support non-profit organizations focused on education, food security, health, and mental health initiatives. Organizations must be 501(c)3 certified and demonstrate community impact with at least 500 volunteer hours. Applications are accepted from March 1 to March 30, and awards are announced by September 15. This initiative aims to empower nonprofits to effectively address pressing community needs.

The Spinks Family Foundation offers small grants to support non-profit organizations dedicated to improving community life in South Carolina. Eligible organizations must be 501(c)(3) certified, with a focus on volunteer engagement and community services. Applications are accepted on a rolling basis and reviewed quarterly, providing essential funding for initiatives in education, health, and food security. This philanthropic effort aims to foster strong, healthy communities and enhance the well-being of residents.

The Weyerhaeuser Giving Fund provides grants to support communities in the U.S. and Canada where the company operates. Focused on affordable housing, education, environmental stewardship, and more, the fund emphasizes projects that meet local needs and demonstrate community support. Eligible organizations include nonprofits and educational institutions. Applications are accepted year-round with a deadline for 2025 on September 30. National initiatives related to working forests are funded by invitation only.

The Bank of America Charitable Foundation focuses on improving economic mobility and social progress through partnerships with nonprofits. It prioritizes basic needs, income creation, stable housing, and community empowerment. By supporting vulnerable populations, the foundation aims to enable individuals to achieve their goals and contribute positively to their communities. The foundation emphasizes sustainable progress, ensuring that all community members have access to essential resources and opportunities for growth.

The Spartanburg Regional Foundation, established in 1991, plays a crucial role in enhancing community health in the Upstate of South Carolina. By supporting projects and initiatives, the Foundation has contributed over $100 million to healthcare efforts. It allocates funds to priority areas such as maternal health, behavioral health, and workforce development. The Foundation aims to empower change through innovative grantmaking, benefiting both Spartanburg Regional Healthcare System and community partners dedicated to improving health outcomes.

The Partnerships for Opportunity and Workforce and Economic Revitalization (POWER) Initiative aims to revitalize communities impacted by coal industry transitions. This initiative provides funding for projects that diversify local economies, enhance job training, and create new employment opportunities. By fostering collaboration among various stakeholders, the POWER Initiative supports strategic investments that align with regional economic development plans, ensuring a more resilient future for coal-affected areas.

Spectrum Digital Education Grants support nonprofit organizations in educating communities about broadband benefits and usage. These grants aim to bridge the digital divide, particularly for seniors and those with disabilities or ethnically diverse backgrounds. Applicants must demonstrate community partnership, address specific needs, and provide measurable impact metrics. With a focus on financial feasibility and meaningful outcomes, this initiative ensures that underrepresented urban and rural communities gain access to essential digital resources, fostering long-term improvement in their lives.

The Bank of America Charitable Foundation focuses on supporting organizations that empower communities through basic needs, income creation, and stable housing. By investing in health and job opportunities, they aim to enhance economic mobility for low- and moderate-income families. Their partnerships target vulnerable populations, ensuring equitable access to resources that foster community vitality and resilience. This initiative emphasizes the importance of stable housing as a foundation for personal and communal growth.

The Cherokee County Community Foundation Grant aims to inspire philanthropy and strengthen the local community by providing funding for projects that address critical needs in areas such as crime and safety, economic development, education, family and youth, and public health. Eligible organizations include 501(c)(3) nonprofits and educational institutions serving Cherokee County, SC. The Foundation prioritizes initiatives that create community gain and improve the quality of life for residents.

The Area Development Grant Program, managed by the Appalachian Regional Commission (ARC), supports economic growth in Appalachia through investments in critical infrastructure and workforce development. Targeting 423 counties across 13 states, the program encourages local communities to collaborate with state governments to identify and implement impactful projects. Key focus areas include enhancing utilities, promoting entrepreneurship, and strengthening local leadership. This initiative aims to uplift the 26 million residents of Appalachia, fostering sustainable economic opportunities.

The Educational Foundation of America (EFA) supports the Reproductive Health & Justice Grant Program to enhance access to abortion and contraception throughout the U.S., particularly in Appalachia, Alabama, and Florida. EFA funds innovative organizations that advocate for reproductive rights, provide direct support to abortion services, and leverage impact investing strategies. This commitment aims to ensure reproductive freedom, foster equity, and promote sustainability in underserved communities.

Indigo Hope Foundation: First Responder Wellness Grant

Supporting programs that provide mental health resources, training, family support, and wellness services for our first responders.

Key Focus Areas:

• Mental Health Support
• Family Services
• Training Programs
• Peer Support

Example Programs We Fund:

• Critical incident stress management
• Family counseling services
• Peer support programs
• Wellness and resilience training

Indigo Hope Foundation: At-Risk Youth Development Grant

Empowering programs that provide mentorship, education, life skills training, and opportunities for young people facing challenges.

Key Focus Areas:

• Mentorship Programs
• Educational Support
• Life Skills Training
• Career Development

Example Programs We Fund:

• After-school tutoring and mentorship
• Job readiness training
• Leadership development

Indigo Hope Foundation: Addiction Recovery Programs Grant

Funding programs that offer treatment, counseling, recovery support services, and harm reduction for individuals battling addiction.

Key Focus Areas:

• Treatment Services
• Recovery Support
• Harm Reduction
• Family Programs

Example Programs We Fund:

• Outpatient counseling programs
• Peer recovery support
• Addiction Recovery Residential Programs
• Family therapy services

The Jean Griswold Foundation

The Jean Griswold Foundation (JGF) is a non-profit organization dedicated to supporting Caregivers through educational opportunities and scholarships. 

Our Mission

The mission of the Jean Griswold Foundation is to support Caregivers by providing educational scholarships* to enable them to further their training, enhance their careers, and better assist the clients they serve.

By offering educational scholarships*, our Foundation will not only make a positive impact on the Caregivers themselves, but also the clients they assist and the home healthcare agencies where they are employed, as well as help advance the overarching home-care industry.

Scholarships will be paid directly to the federally accredited educational institutions of the winning Scholars’ choosing.

Empowering Caregivers Through Education

The Jean Griswold Foundation Scholarship Program awards scholarships to deserving Caregivers who wish to further their education in a care-related field. Applicants do not have to be associated with Griswold in any way, and the funds will be paid directly to the institution where the caregiver will be receiving education.  

Our Winter 2026 Scholarship Application period is now open! Applications will be accepted until 11:59pm ET August 31, 2026. Join our email list to get the first notice of all Scholarship happenings.  

Where would we be without Caregivers? 

Their selflessness is astounding, yet they are often overlooked and underappreciated. 

The Jean Griswold Foundation is dedicated to supporting Caregivers, the backbone of the care industry. We provide educational scholarships so Care Professionals can further their training, enhance their skills, elevate their careers, and better assist the people they serve.

The Duke Energy Foundation offers Local Impact Grants to enhance the quality of life in South Carolina. Grants up to $20,000 support initiatives in vibrant economies, climate resiliency, and opportunity and inclusion. Eligible organizations must serve communities powered by Duke Energy and meet specific tax-exempt criteria. The foundation prioritizes projects that promote environmental sustainability and community development, while emphasizing non-discrimination and measurable impact.

The Georgia-Pacific Foundation Grant supports organizations in the Metro Atlanta area, focusing on education, entrepreneurship, community enrichment, and environmental sustainability. Established in 1958, the foundation prioritizes investments that align with its mission and values, promoting long-term well-being within communities where Georgia-Pacific operates. Eligible applicants include 501(c)(3) nonprofits, public schools, and local government entities located within 30 miles of GP manufacturing sites.

South Carolina Department of Commerce

From site selection to infrastructure improvement, we are here to help grow new and existing businesses.

SC Commerce promotes economic opportunity for individuals and businesses through initiatives like workforce training. As a national leader in foreign direct investment, the state extends its global reach with offices in Europe and Asia that help existing companies in developing export markets.

South Carolina Community Development Block Grant

The South Carolina Community Development Block Grant (“State CDBG Program”) is designed to aid units of general local government in improving economic opportunities and meeting community revitalization needs, particularly for persons of low- and moderate-income. The State CDBG Program has been funded through the State since 1982 by the U.S. Department of Housing and Urban Development (HUD) under the Housing and Community Development Act of 1974, as amended (Title I). 

CDBG Program Goals and Outcomes

The SC Department of Commerce seeks to improve the well-being of all South Carolinians in a manner that supports and enhances a high quality of life. The State CDBG Program supports the agency’s efforts to strengthen communities through revitalization and improvement of neighborhoods, public infrastructure, and the local economy. 

The three overarching goals of the HUD CDBG program are to provide decent housing, economic opportunities and a suitable living environment. Within the context of these goals, each project funded by the State must also meet one of three outcomes identified by HUD: affordability, accessibility, or sustainability. 

Local Match/Leveraging

CDBG projects are expected to leverage other public and private investments and serve as a catalyst for future development.

There must be a 10% match of the total CDBG request, unless otherwise approved, which can come from a variety of committed sources including other grants, loans, waiver of fees, public or private investments, and documented volunteer or in-kind contributions. Matching funds must be immediately available for the project at the time of application. 

Community Development Block Grant Categories

There are three broad grant program categories: Community Development, Business Development, and Regional Planning. The Community Development Program is further broken down into several subcategories to address infrastructure, community facilities, and local priorities.

Community Development Programs

Description

This program is designed to produce outcomes that improve citizens’ quality of life and create a competitive environment for jobs and investment by addressing priority community development needs. Activities should contribute to healthy, safe and sustainable neighborhoods and communities. These grants are designed to improve the quality of life for distressed and LMI communities. Community Development projects will compete within the following subcategories that have the same general submission requirements, except that the Ready to Go Program will not be funded in a competitive funding round.

Community Development Program Categories: Community Infrastructure; Community Enrichment; Local Priorities Program; and Ready to Go Program

Ready To Go Program

Outcome

This program is designed to stimulate the local economy by addressing urgent or compelling community needs. Funding may also be used for pilot projects which have been developed in coordination with, and have been approved by, the State CDBG Program. The goal is encouraging innovation, the timely implementation of CDBG eligible projects, and cost effectiveness. The project requires an upfront investment of local and other funds for planning, project design and permitting that is substantially equivalent to the required 10% local match.

The project must be an eligible public facility improvement under the Community Infrastructure, Community Enrichment, or Local Priorities program. All required project activities leading up to bidding must be complete prior to submission of the application including but not limited to project design, environmental review, acquisition and permits. CDBG funds may only be used for construction or demolition.