Best Lexington County Grants for Nonprofits in South Carolina

Every Dream of Parenthood Deserves a Chance

Making dreams of parenthood a reality, one grant and one bundle of joy at a time.

Our Mission

The Samantha and Kyle Busch Bundle of Joy Fund is dedicated to advancing access to IVF care and coverage, increasing awareness and providing support so others don’t have to navigate infertility alone.

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Your Journey to Parenthood Begins Here

We distribute grant awards up to three times annually.

Please note that the number of grants and funding amounts fluctuate based on:

1) the unique needs of our applicants, and

2) the success of our fundraising efforts.

Our mission is to help as many people as possible.

501(c)(3) nonprofits serving children and families in need in Lexington County, South Carolina can apply for GSF Foundation’s support to improve quality of life through basic needs and education-related programs. Eligible organizations must be nominated by, and apply through, a current GSF associate living or working in the community.

International Paper Grants focus on community engagement, emphasizing education, hunger relief, health & wellness, and disaster relief. They support nonprofit organizations that demonstrate good financial standing and effective management. Eligible organizations must operate in areas where International Paper has facilities. The foundation prioritizes local needs, particularly critical and environmental issues, while encouraging employee involvement. Ineligible entities include private foundations and those without a local presence. Applications are accepted through mid-September in the U.S. and Canada.

Lexington County, South Carolina 501(c)(3) nonprofits, public schools, and qualified local governments serving low- to moderate-income and historically underserved communities can receive funding for staff job-related classes and certification courses. With a mission to strengthen community-focused organizations, TD Charitable Foundation provides the Nonprofit Resource Training Grant, offering up to US $1,000 for upcoming employee training within TD Bank market areas.

The Do it Best Foundation Grant supports nonprofit organizations focused on community needs, particularly in health and wellness, youth enrichment, the arts, and community development. Grants typically range from $5,000 to $20,000, with no strict limits based on quarterly applications. Eligible organizations must have 501(c)(3) status and be located near specific areas. This initiative aims to enhance community resources and foster connections among residents.

Eligible 501(c)(3) nonprofits in Lexington County, South Carolina with budgets under $450,000 can receive up to US $30,000 in multi-year general operating support for staffing, administration, and other core needs. Central Carolina Community Foundation prioritizes smaller, community-rooted organizations that have previously received CCCF funding and are registered on Midlands Gives.

With a mission to support forestry and habitat restoration, this program provides Lexington County, South Carolina conservation partners with US $250,000 - US $3,000,000 for on-the-ground longleaf pine and bottomland hardwood forest projects. Eligible organizations can propose voluntary restoration, enhancement, and conservation work within the historical longleaf pine range through the National Fish and Wildlife Foundation’s Longleaf Landscape Stewardship Fund.

Nonprofit and charitable organizations in Lexington County, South Carolina can receive up to US $5,000 to strengthen organizational capacity, stability, and governance. With a mission to build stronger nonprofits, Central Carolina Community Foundation provides funding for projects like strategic planning, board development, technology or facilities planning, disaster planning, and inclusion, diversity, equity and access (IDEA) efforts.

Lexington Medical Center Foundation Inc

Since 1971, Lexington Health has grown and expanded to meet the needs of our community. The Lexington Health Foundation Remains Committed to Quality Care. Foundation-funded programs aim to enhance patient experiences and touch the various areas of care at Lexington Health — Patient, Employee, and Community Care.

Event and Project Sponsorship

Lexington Medical Center supports local organizations and nonprofits throughout the Midlands.

We support local events and causes that enhance the health and vibrance of our community. You can request sponsorship or other assistance for a project or event based in the South Carolina Midlands community.

Nonprofit, public, educational, and faith-based organizations in Lexington County, South Carolina and the wider Midlands can seek challenge grants of US $10,000 - US $60,000 to launch or expand projects improving community livability and attachment. Central Carolina Community Foundation funds new initiatives that enhance safe housing, jobs, health access, recreation, arts, and community connections.

The Spinks Family Foundation offers small grants to support non-profit organizations dedicated to improving community life in South Carolina. Eligible organizations must be 501(c)(3) certified, with a focus on volunteer engagement and community services. Applications are accepted on a rolling basis and reviewed quarterly, providing essential funding for initiatives in education, health, and food security. This philanthropic effort aims to foster strong, healthy communities and enhance the well-being of residents.

Lexington County, South Carolina nonprofits focused on education, children, food security, health, or substance abuse and mental health can access funding through Spinks Family Foundation’s Large Grant Request program. Eligible 501(c)(3) organizations with strong local volunteer engagement and programs in the Upstate, Midlands, and Lowcountry regions may receive awards of more than US $10,000.

Nonprofit, public, educational, and faith-based organizations serving the Greater Chapin area of Lexington County, South Carolina can access funding through Central Carolina Community Foundation to address a broad range of community service needs. Grants of approximately US $1,000 support projects that build skills, expand opportunities for underserved residents, and strengthen individual, family, or community assets.

Lexington County, South Carolina 501(c)(3) nonprofits improving community health and healthcare access can seek support for programs serving the Midlands. Focus areas include reducing health disparities, increasing services for underserved and at-risk populations, health education and prevention, and strengthening safety-net providers through Lexington Medical Center Foundation’s organization grants.

The Brinker International Charitable Giving Program focuses on giving back to communities through support for kids, hunger, and education. Organizations eligible for funding must be 501c(3) non-profits and submit requests at least six weeks prior to events. The program does not support individuals, political or religious organizations, or explicit discrimination policies. Funding is provided through monetary donations or in-kind contributions like dining certificates.

Grants from Westinghouse help Lexington County, South Carolina 501(c)(3) nonprofits and eligible schools fund STEM education, environmental sustainability, and community safety and wellness initiatives near Westinghouse sites. Organizations must be tax-exempt and located within 50 miles of a listed Westinghouse facility to be considered.

Nonprofit and for-profit organizations hosting community-focused events or activities in Lexington County, South Carolina can access funding through TD Charitable Foundation’s TD Bank Community Sponsorships Program. Grants support public events that positively impact the community, offer networking and participation opportunities for bank colleagues, and help strengthen relationships with local organizations.

Lexington County, South Carolina 501(c)(3) nonprofits working on economic mobility, workforce readiness, or affordable housing can access funding through Bank of America Charitable Foundation’s Neighborhood Builders Program. Selected organizations receive a two-year leadership development experience plus a capacity-building grant, supporting income creation, small business resilience, and stable, affordable housing initiatives in eligible local markets.

Nonprofit organizations running arts, education, environmental, or health and wellness projects or events in Lexington County, South Carolina may be eligible for support. With a mission to strengthen communities, Stantec provides funding and other assistance for community initiatives and events, with preference for those located near its offices and aligned with its values.

The Housing for Everyone Grant Competition, part of the 2026 Initiative, aims to support eviction prevention in low-to moderate-income communities. This 20th annual initiative recognizes the destabilizing impact of eviction and displacement on families, which leads to job loss, school disruptions, and health issues. By funding innovative organizations, the competition seeks to provide stability for renters, enabling them to stay in their homes and communities.

The Lipscomb Family Foundation Grant supports youth development in the South Carolina Midlands, focusing on character building and educational opportunities. Established by Margaret and Guy Lipscomb, the foundation aims to foster inquisitive, productive, and caring individuals under 19 years of age. Grants are typically awarded to 501(c)(3) organizations in specific counties, promoting positive growth within the community and enhancing relationships among families. This initiative is dedicated to shaping the next generation of responsible and healthy adults.

501(c)(3) nonprofits working on affordable housing, skilled trades training, clean water, sanitation, or community economic development in Lexington County, South Carolina can apply for Ferguson’s Ferguson Cares Grant. Eligible organizations must be within Ferguson’s geographic footprint and based in the U.S., supporting local communities where the company has a strong business presence.

Nonprofit 501(c)(3) organizations in Lexington County, South Carolina that run digital literacy or broadband education programs for families or seniors may be eligible for Spectrum Digital Education Grants from Charter Communications. Awards of US $2,500 - US $50,000 support existing programs that bridge the digital divide in low-income or multicultural communities and can report clear impact metrics.

The First Horizon Foundation, established by First Horizon National Corp., supports communities in Florida, North Carolina, and South Carolina. Since 1993, it has donated over $90 million to enhance lives through grants focused on arts, education, environment, financial literacy, and health services. Eligible nonprofits in various cities can apply, while individuals and certain organizations, such as K-12 schools and political groups, are excluded from funding. This foundation is dedicated to making a positive impact in the regions it serves.

Central Carolina Community Foundation provides Lexington County, South Carolina nonprofits with grants supporting health, well-being, and education programs. 501(c)(3) organizations with a physical location in South Carolina may apply for US $1,000 - US $10,000, with preference for pediatric cancer services and life skills or traditional educational initiatives serving local communities.

Graduating high school seniors and current undergraduates in Lexington County, South Carolina and nearby counties can apply for Central Carolina Community Foundation’s renewable Opportunity Scholarship, awarding $2,000 for accredited two- or four-year programs. First-generation students with financial need who are active in their communities and attending local nonprofit colleges may be eligible.

Nonprofit organizations in Lexington County, South Carolina working on health, education, environmental, or community services can seek more than US $5,000 to support local programs. With a mission to improve quality of life, TD Charitable Foundation prioritizes initiatives in Better Health, Connected Communities, Financial Security, and Vibrant Planet, especially for diverse or historically underserved, low-to-moderate income populations.