Best Greenville Grants for Nonprofits in South Carolina

Greenville, South Carolina 501(c)(3) nonprofits and government units can access funding through the Community Foundation of Greenville for high-impact projects in arts, education, environment, health, and human services. Greenville Women Giving awards US $50,000 - US $100,000 grants annually for initiatives serving residents of Greenville County, South Carolina.

Nonprofit 501(c)(3) organizations serving Greenville, South Carolina can seek funding for programs that advance economic mobility, education, housing, transportation, and employment. With a mission to remove systemic barriers, Hollingsworth Funds provides US $15,000 - US $500,000 for general operating, capital, or project support benefiting Greenville County residents, especially low-income Black and Hispanic/Latinx communities.

The CFG Capacity Building Grants support established 501(c)(3) organizations in Greenville County, SC, aiming to enhance their operational capabilities and governance. Funding opportunities include projects for client engagement, management innovation, collaborative ventures, technology improvements, and revenue diversification. Examples of capacity building encompass financial planning, organizational assessments, strategic planning, and leadership development. Grants are awarded competitively, allowing one application per agency per year, excluding individuals and certain ineligible expenses.

Greenville, South Carolina 501(c)(3) nonprofits focused on economic mobility, workforce readiness, entrepreneurship, or affordable housing can access funding through Bank of America Charitable Foundation’s Neighborhood Builders Program. Selected organizations receive a two-year leadership development experience plus capacity-building support, if they meet revenue thresholds and other organizational readiness requirements in eligible markets.

Greenville, South Carolina 501(c)(3) nonprofits and local municipalities preserving parks, open spaces, or historic and cultural assets can access funding through Community Foundation of Greenville’s New Leaf Fund. Grants of US $20,000 - US $100,000 support land and waterfront protection, increased tree cover, green infrastructure, and related projects primarily in Greenville County and the broader Upstate.

Minority-led 501(c)(3) nonprofits in Greenville, South Carolina with budgets of $250,000+ can receive US $5,000 - US $12,500 for operating or program support. With a mission to improve Greenville County residents’ lives, Community Foundation of Greenville prioritizes organizations led by people of color or serving disadvantaged neighborhoods, especially Black and Hispanic communities, students, and older adults.

Nonprofit 501(c)(3) organizations addressing basic needs, income creation, housing stability, or community empowerment in Greenville, South Carolina can access funding through Bank of America Charitable Foundation. Grants support economic mobility efforts for low- and moderate-income communities, including workforce development, small business resiliency, and community development for vulnerable populations such as families, youth, seniors, veterans, and people with disabilities.

The Housing for Everyone Grant Competition, part of the 2026 Initiative, aims to support eviction prevention in low-to moderate-income communities. This 20th annual initiative recognizes the destabilizing impact of eviction and displacement on families, which leads to job loss, school disruptions, and health issues. By funding innovative organizations, the competition seeks to provide stability for renters, enabling them to stay in their homes and communities.

Public and private K–12 schools that are identified ArtsNOW partner schools can access funding to expand arts integration and professional learning in Greenville, South Carolina. Grants from South Carolina Arts Commission support multi-year arts integration training, demonstration lessons, curriculum mapping, and planning to engage students, equip educators, and strengthen school communities.

New Leaf Fund - Spring Cycle

The New Leaf Fund was established in 2025 by a Greenville native with a passion for conservation.

The Foundation encourages grant requests that include the protection of land and waterfront areas, increased tree cover and access to green spaces, and the protection and restoration of historical properties, in the City of Greenville, in Greenville County, and, to a lesser degree, in the Upstate.

Additional Information

• Awards typically range from $20,000 to $100,000
• Applicants may apply for more than one grant annually

Funding opportunities may include

Funding opportunities may include

• Projects including acquisition, development, preservation, or restoration of land
• Projects including acquisition, development, preservation, or restoration of historical and cultural assets
• Planning, survey, appraisal or design fees for implementing such projects

BASF Corporation, a leading chemical company based in Florham Park, New Jersey, is committed to charitable giving that aligns with its corporate social responsibility goals. The focus areas include science education, environmental sustainability, and health and safety. Donations are only made to eligible non-profit organizations under the U.S. Internal Revenue Code, ensuring that contributions support initiatives that enhance the quality of life in BASF communities and promote a sustainable future.

New Leaf Fund - Summer Cycle

Community Foundation of Greenville administers grants to preserve parks, open spaces, and historical and cultural assets through the New Leaf Fund.

The New Leaf Fund was established in 2025 by a Greenville native with a passion for conservation.

The Foundation encourages grant requests that include the protection of land and waterfront areas, increased tree cover and access to green spaces, and the protection and restoration of historical properties, in the City of Greenville, in Greenville County, and, to a lesser degree, in the Upstate.

Additional Information

• Awards typically range from $20,000 to $100,000
• Applicants may apply for more than one grant annually
• Funding opportunities may include
• Projects including acquisition, development, preservation, or restoration of land
• Projects including acquisition, development, preservation, or restoration of historical and cultural assets
• Planning, survey, appraisal or design fees for implementing such projects

Spectrum Digital Education Grants support nonprofit organizations in educating communities about broadband benefits and usage. These grants aim to bridge the digital divide, particularly for seniors and those with disabilities or ethnically diverse backgrounds. Applicants must demonstrate community partnership, address specific needs, and provide measurable impact metrics. With a focus on financial feasibility and meaningful outcomes, this initiative ensures that underrepresented urban and rural communities gain access to essential digital resources, fostering long-term improvement in their lives.

The SC Christian Foundation offers Community Trust Grants designed to support Christian non-profit organizations that share the Gospel beyond the church walls. Eligible ministries must complete a Ministry Introduction Form for review. Grants are awarded annually, with proposals released in July and announcements made in October. This initiative aims to address the evolving needs of communities in South Carolina, particularly in Spartanburg, Greenville, York, Horry, and Georgetown Counties.

The Spinks Family Foundation offers small grants to support non-profit organizations dedicated to improving community life in South Carolina. Eligible organizations must be 501(c)(3) certified, with a focus on volunteer engagement and community services. Applications are accepted on a rolling basis and reviewed quarterly, providing essential funding for initiatives in education, health, and food security. This philanthropic effort aims to foster strong, healthy communities and enhance the well-being of residents.

The Ferguson Cares Grant is an essential aspect of Ferguson's Sustainability strategy, focusing on social challenges and community wellbeing. This grant supports nonprofit organizations in the U.S. dedicated to affordable housing, skilled trades workforce development, clean water access, and enhancing local economic quality of life. Ferguson aims to create lasting partnerships that drive positive impact within their operational regions, reflecting their commitment to social responsibility and community support.

The Spinks Family Foundation provides large grants of $10,000 and above annually to support non-profit organizations focused on education, food security, health, and mental health initiatives. Organizations must be 501(c)3 certified and demonstrate community impact with at least 500 volunteer hours. Applications are accepted from March 1 to March 30, and awards are announced by September 15. This initiative aims to empower nonprofits to effectively address pressing community needs.

With a mission to strengthen communities, PNC Foundation provides Greenville, South Carolina nonprofits with funding for early childhood education and economic development initiatives. Eligible 501(c)(3) organizations serving low- and moderate-income children and families in areas where PNC has a significant presence may seek support for education, community development, affordable housing, arts, and essential human services.

Greenville, South Carolina 501(c)(3) nonprofits seeking more than US $20,000 for capital or other mission-aligned projects can apply for the F. W. Symmes Foundation Grant. Funding supports programs benefiting Greenville County residents across arts, education, health, human services, environment, religion, and public benefit, with priority given to capital projects and sustainable initiatives.

The IMA Foundation Grant focuses on empowering communities by supporting nonprofit organizations dedicated to workforce development, financial security for families, and enhancing emergency preparedness. With a mission to provide philanthropic assistance, the foundation seeks partners that align with its vision and operational reach. Organizations must be 501c3 nonprofits and serve areas where IMA has offices, ensuring that their initiatives directly impact youth under 26 years of age.

The Lynn Thornhill Scholarship, managed by the Beckley Area Foundation, supports students at Furman University in their pursuit of higher education. This scholarship is part of a broader initiative to facilitate charitable giving and enhance educational opportunities in Southern West Virginia. By providing financial assistance, the foundation aims to inspire students to achieve their academic goals and contribute positively to their communities.

The Indigo Hope Foundation offers grants to organizations in the Upstate of South Carolina, focusing on addiction, homelessness, at-risk youth, veterans, and first responders. They award between $250 and $100,000, prioritizing projects that demonstrate measurable results and address critical community needs. Eligible applicants must be 501(c)(3) tax-exempt or government units, with only one application allowed per grant period. The foundation emphasizes collaboration and favors faith-based organizations.

About PLTW Computer SciencePLTW Computer Science students are technology trailblazers who are empowered through transportable skills and prepared to start their career, whether that is in computer science or not.3M has partnered with PLTW to ensure students and teachers have the tools, resources and knowledge they need to succeed in STEM. 3M inspires the next generation of science leaders through the following goals:

• Increasing STEM exposure in K-12 classrooms
• Supporting experiential learning opportunities enhancing the quality of STEM teaching
• Providing professional development opportunities for students

Program Requirements:

• Grantee must use their grant funds to expand their existing PLTW Computer Science program.
  • Example expansion activities include but are not limited to adding an additional PLTW Computer Science  course not previously offered,
  • and/or adding additional class periods of an existing PLTW Computer Science courses previously offered,
  • and/or training additional teachers in PLTW Computer Science courses for the 2027-2028 academic year. 

Grant Award and Distribution Schedule:

• Total Award: $5,000
  • 2027-2028: $5,000

Small 501(c)(3) nonprofits focused on social mobility, financial wellness, or workforce education in Greenville, South Carolina can seek Truliant Mini Grants for staff and board training or key program materials. Focused on community capacity building, Truliant Federal Credit Union offers up to US $2,500 to organizations in Truliant member communities with budgets under $500,000.

Nonprofit organizations in Greenville, South Carolina working on arts and culture, education, environmental sustainability, financial literacy, or health and human services may be eligible for project support. Grants from First Horizon Foundation help 501(c)(3) groups in designated Greenville County communities strengthen long-term community well-being across these focus areas.

About PLTW EngineeringPLTW Engineering students adopt a problem-solving mindset, are engaged in compelling, real-world challenges that help them become better collaborators and thinkers, and are prepared with skills to step into any career path they take.3M has partnered with PLTW to ensure students and teachers have the tools, resources and knowledge they need to succeed in STEM. 3M inspires the next generation of science leaders through the following goals:

• Increasing STEM exposure in K-12 classrooms
• Supporting experiential learning opportunitiesEnhancing the quality of STEM teaching
• Providing professional development opportunities for students

Program Requirements:

• Grantee must use their grant funds to expand their existing PLTW Engineering program.
  • Example expansion activities include but are not limited to adding an additional PLTW Engineering course not previously offered,
  • and/or adding additional class periods of an existing PLTW Engineering courses previously offered,
  • and/or training additional teachers in PLTW Engineering courses for the 2027-2028 academic year. 

Grant Award and Distribution Schedule:

• Total Award: $10,000
  • 2027-2028: $10,000

About PLTW GatewayPLTW Gateway (6-8) opens paths that create meaningful futures. It connects students to careers in areas they can, and can't, imagine.3M has partnered with PLTW to ensure students and teachers have the tools, resources and knowledge they need to succeed in STEM. 3M inspires the next generation of science leaders through the following goals:

• Increasing STEM exposure in K-12 classrooms
• Supporting experiential learning opportunitiesEnhancing the quality of STEM teaching
• Providing professional development opportunities for students

Program Requirements:

• The purpose of this grant is to assist the grantee's implementation of the PLTW Gateway program.
• Grantee must offer at least one PLTW Gateway unit in the 2027-2028 academic year.
• Grantee may implement any PLTW Gateway unit of their choosing.

Grant Award and Distribution Schedule:

• Total Award: $10,000
  • 2027-2028: $10,000