Best Greenville Grants for Nonprofits in South Carolina

The W. W. Burgiss Charities Grant supports initiatives focused on religion, education, and assistance for the needy in Greenville County, South Carolina. Established by W. W. Burgiss in 1925, the foundation prioritizes capital needs and one-time special projects, aiming to create measurable impacts. Eligible organizations must be 501(c)(3) exempt and demonstrate financial sustainability. With an average grant size of $12,000, the foundation aims to uplift the sick and underprivileged, ensuring local community enhancement through targeted funding.

The Partnerships for Opportunity and Workforce and Economic Revitalization (POWER) Initiative aims to revitalize communities impacted by coal industry transitions. This initiative provides funding for projects that diversify local economies, enhance job training, and create new employment opportunities. By fostering collaboration among various stakeholders, the POWER Initiative supports strategic investments that align with regional economic development plans, ensuring a more resilient future for coal-affected areas.

The Jean Griswold Foundation

The Jean Griswold Foundation (JGF) is a non-profit organization dedicated to supporting Caregivers through educational opportunities and scholarships. 

Our Mission

The mission of the Jean Griswold Foundation is to support Caregivers by providing educational scholarships* to enable them to further their training, enhance their careers, and better assist the clients they serve.

By offering educational scholarships*, our Foundation will not only make a positive impact on the Caregivers themselves, but also the clients they assist and the home healthcare agencies where they are employed, as well as help advance the overarching home-care industry.

Scholarships will be paid directly to the federally accredited educational institutions of the winning Scholars’ choosing.

Empowering Caregivers Through Education

The Jean Griswold Foundation Scholarship Program awards scholarships to deserving Caregivers who wish to further their education in a care-related field. Applicants do not have to be associated with Griswold in any way, and the funds will be paid directly to the institution where the caregiver will be receiving education.  

Our Winter 2026 Scholarship Application period is now open! Applications will be accepted until 11:59pm ET August 31, 2026. Join our email list to get the first notice of all Scholarship happenings.  

Where would we be without Caregivers? 

Their selflessness is astounding, yet they are often overlooked and underappreciated. 

The Jean Griswold Foundation is dedicated to supporting Caregivers, the backbone of the care industry. We provide educational scholarships so Care Professionals can further their training, enhance their skills, elevate their careers, and better assist the people they serve.

The Hathaway Family Foundation Grant aims to enhance the lives of individuals in need within Greenville, South Carolina. This private foundation focuses on improving food security, access to quality healthcare, conservation efforts, and addressing homelessness. By supporting organizations that provide temporary shelters, mental health care, and food distribution, the foundation ensures targeted assistance for the most vulnerable populations. The foundation's commitment reflects a dedication to fostering community well-being and positive change.

Academy Sports + Outdoors, a leading sporting goods retailer, supports community initiatives by providing donations to registered 501(c)(3) organizations. Their focus is on promoting safety and responsibility in sports and outdoor activities. Proposals must foster community engagement and must not be affiliated with religious or political groups. Events should take place in areas with Academy stores, ensuring a positive local impact while encouraging active lifestyles and connection among community members.

The Lynn Thornhill Scholarship, managed by the Beckley Area Foundation, supports students at Furman University in their pursuit of higher education. This scholarship is part of a broader initiative to facilitate charitable giving and enhance educational opportunities in Southern West Virginia. By providing financial assistance, the foundation aims to inspire students to achieve their academic goals and contribute positively to their communities.

Greenville, South Carolina 501(c)(3) nonprofits focused on economic mobility, workforce readiness, entrepreneurship, or affordable housing can access funding through Bank of America Charitable Foundation’s Neighborhood Builders Program. Selected organizations receive a two-year leadership development experience plus capacity-building support, if they meet revenue thresholds and other organizational readiness requirements in eligible markets.

The Saint-Gobain Corporation Foundation Direct Grants program provides support to non-profit organizations in focus areas including STEM education, sustainable construction, and workforce development. The foundation aims to foster community development and environmental stewardship. Eligible applicants include IRS-recognized 501(c)(3) organizations and accredited educational institutions in the U.S. The Foundation prioritizes partnerships that allow employee involvement and volunteer support, aiming to build meaningful relationships with grantees.

The Educational Foundation of America (EFA) supports the Reproductive Health & Justice Grant Program to enhance access to abortion and contraception throughout the U.S., particularly in Appalachia, Alabama, and Florida. EFA funds innovative organizations that advocate for reproductive rights, provide direct support to abortion services, and leverage impact investing strategies. This commitment aims to ensure reproductive freedom, foster equity, and promote sustainability in underserved communities.

Nonprofit organizations in Greenville, South Carolina working on arts and culture, education, environmental sustainability, financial literacy, or health and human services may be eligible for project support. Grants from First Horizon Foundation help 501(c)(3) groups in designated Greenville County communities strengthen long-term community well-being across these focus areas.

Nonprofit 501(c)(3) organizations addressing basic needs, income creation, housing stability, or community empowerment in Greenville, South Carolina can access funding through Bank of America Charitable Foundation. Grants support economic mobility efforts for low- and moderate-income communities, including workforce development, small business resiliency, and community development for vulnerable populations such as families, youth, seniors, veterans, and people with disabilities.

With a mission to strengthen communities, PNC Foundation provides Greenville, South Carolina nonprofits with funding for early childhood education and economic development initiatives. Eligible 501(c)(3) organizations serving low- and moderate-income children and families in areas where PNC has a significant presence may seek support for education, community development, affordable housing, arts, and essential human services.

Nonprofit organizations running community, health, education, or environmental programs in Greenville, South Carolina can apply for TD Charitable Foundation’s regional grants of more than US $5,000. With a mission to improve quality of life, the foundation favors initiatives serving diverse, historically underserved, and low-to-moderate income residents through its TD Ready Commitment focus areas.

The PNC Foundation's Grow Up Great Grant is a significant initiative aimed at enhancing educational opportunities for children from birth to age 5. With a commitment of $500 million, this program focuses on improving school readiness through support in vocabulary development, social-emotional learning, and the arts. By partnering with community-based nonprofits, PNC aims to foster stronger, smarter, and healthier communities, ensuring a brighter future for the next generation.

The Brinker International Charitable Giving Program focuses on giving back to communities through support for kids, hunger, and education. Organizations eligible for funding must be 501c(3) non-profits and submit requests at least six weeks prior to events. The program does not support individuals, political or religious organizations, or explicit discrimination policies. Funding is provided through monetary donations or in-kind contributions like dining certificates.

Eligible 501(c)(3) nonprofits and government entities in Greenville, South Carolina can apply for Duke Energy Foundation’s Local Impact Grants, awarding up to US $20,000 for community-focused projects. Funding supports workforce development, STEM education, economic development, climate resiliency, disaster preparedness, environmental conservation, and opportunity and inclusion initiatives in Duke Energy–served South Carolina counties.

Grants help Greenville, South Carolina nonprofits providing animal welfare, human services, environmental programs, or support for veterans with capital, operating, or program needs. Grants from the First Lieutenant Peter F. Cureton Jr. Foundation are available to 501(c)(3) organizations serving children, people with disabilities, indigent populations, and veterans in Greenville County.

Nonprofit 501(c)(3) organizations serving underrepresented children, PreK–12 students, or families in Greenville, South Carolina may be eligible for community-focused funding that supports direct program needs. Focused on education, child wellbeing, and community-based family support, the ScanSource Charitable Foundation prioritizes impactful services and meaningful volunteer opportunities within its Greenville County footprint.

Project Lead the Way (PLTW) provides innovative, hands-on learning experiences for students in PreK-5, fostering confidence and career readiness. With support from 3M, PLTW Launch aims to enhance STEM education by increasing exposure, supporting experiential learning, and improving teaching quality. This partnership ensures that students and teachers have the necessary tools and resources to thrive in a rapidly evolving world, empowering the next generation of leaders in science and technology.

Project Lead the Way inc.

School and district leaders need a solution that cultivates confidence and career readiness—and PLTW checks all the boxes. As a nonprofit organization founded by educators and driven by education leaders, we've spent more than 28 years equipping students with the technical knowledge, transferable skills, and career confidence they need to thrive—through programs that integrate real-world industry partnerships, best-in-class teacher training, and our proven activity-, project-, problem-based (APB) instructional model. At PLTW, we're on a mission to create a transformative learning environment and empower students to develop in-demand knowledge and skills necessary to thrive in an evolving world. 

PLTW Computer Science

PLTW Computer Science students are technology trailblazers who are empowered through transportable skills and prepared to start their career, whether that is in computer science or not. Empower your students to become creators of the technology all around them. PLTW Computer Science engages students in collaborative projects that help them develop in-demand computer science knowledge as well as transportable skills like creative thinking and communication. And whether they’re creating an online art gallery or using automation to process and analyze DNA-sequence data, PLTW Computer Science students are seeing how their learning connects to the real world.

PLTW Computer Science - New Program (3M)

3M forms lasting partnerships with communities and provides resources to help them succeed and grow – ensuring a more interconnected and thriving world. 3M inspires the next generation of science leaders through the following goals:

• Increasing STEM exposure in K-12 classrooms
• Supporting experiential learning opportunities
• Enhancing the quality of STEM teaching
• Providing professional development opportunities for students

3M has partnered with PLTW to ensure students and teachers have the tools, resources and knowledge they need to succeed in STEM.

The Piedmont Natural Gas Company Grant Program, part of the Duke Energy Foundation, supports community vitality through grants of $20,000 or less. Focus areas include vibrant economies, climate resiliency, and promoting opportunity and inclusion. Eligible organizations must have tax-exempt status and serve communities without discrimination. The foundation prioritizes measurable community impact and does not fund certain entities, including for-profits and religious organizations. Applications are accepted year-round on a rolling basis.

Greenville, South Carolina 501(c)(3) nonprofits and local municipalities preserving parks, open spaces, or historic and cultural assets can access funding through Community Foundation of Greenville’s New Leaf Fund. Grants of US $20,000 - US $100,000 support land and waterfront protection, increased tree cover, green infrastructure, and related projects primarily in Greenville County and the broader Upstate.

Minority-led 501(c)(3) nonprofits in Greenville, South Carolina with budgets of $250,000+ can receive US $5,000 - US $12,500 for operating or program support. With a mission to improve Greenville County residents’ lives, Community Foundation of Greenville prioritizes organizations led by people of color or serving disadvantaged neighborhoods, especially Black and Hispanic communities, students, and older adults.

Project Lead the Way inc.

School and district leaders need a solution that cultivates confidence and career readiness—and PLTW checks all the boxes. As a nonprofit organization founded by educators and driven by education leaders, we've spent more than 28 years equipping students with the technical knowledge, transferable skills, and career confidence they need to thrive—through programs that integrate real-world industry partnerships, best-in-class teacher training, and our proven activity-, project-, problem-based (APB) instructional model. At PLTW, we're on a mission to create a transformative learning environment and empower students to develop in-demand knowledge and skills necessary to thrive in an evolving world. 

PLTW Engineering

PLTW Engineering students adopt a problem-solving mindset, are engaged in compelling, real-world challenges that help them become better collaborators and thinkers, and are prepared with skills to step into any career path they take. Each PLTW Engineering course engages students in interdisciplinary activities like working with a client to design a home, programming electronic devices or robotic arms, or exploring algae as a biofuel source. These activities not only build knowledge and skills in engineering, but also empower students to develop essential skills such as problem solving, critical and creative thinking, communication, collaboration, and perseverance.

PLTW Engineering - New Program (3M) 

3M forms lasting partnerships with communities and provides resources to help them succeed and grow – ensuring a more interconnected and thriving world. 3M inspires the next generation of science leaders through the following goals:

• Increasing STEM exposure in K-12 classrooms
• Supporting experiential learning opportunities
• Enhancing the quality of STEM teaching
• Providing professional development opportunities for students

3M has partnered with PLTW to ensure students and teachers have the tools, resources and knowledge they need to succeed in STEM.

Greenville, South Carolina 501(c)(3) nonprofits seeking more than US $20,000 for capital or other mission-aligned projects can apply for the F. W. Symmes Foundation Grant. Funding supports programs benefiting Greenville County residents across arts, education, health, human services, environment, religion, and public benefit, with priority given to capital projects and sustainable initiatives.

BASF Corporation, a leading chemical company based in Florham Park, New Jersey, is committed to charitable giving that aligns with its corporate social responsibility goals. The focus areas include science education, environmental sustainability, and health and safety. Donations are only made to eligible non-profit organizations under the U.S. Internal Revenue Code, ensuring that contributions support initiatives that enhance the quality of life in BASF communities and promote a sustainable future.

Spectrum Digital Education Grants support nonprofit organizations in educating communities about broadband benefits and usage. These grants aim to bridge the digital divide, particularly for seniors and those with disabilities or ethnically diverse backgrounds. Applicants must demonstrate community partnership, address specific needs, and provide measurable impact metrics. With a focus on financial feasibility and meaningful outcomes, this initiative ensures that underrepresented urban and rural communities gain access to essential digital resources, fostering long-term improvement in their lives.