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Best Financial Assistance Grants in South Dakota

Find the perfect Financial Assistance Grants in South Dakota on Instrumentl. 9,000+ Financial Assistance Grants in South Dakota in the United States.

9,000+

Available grants

$2.62B

Total funding

$5K

Median grant

9,000+ grants
$2.62B total
$5K median

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9,210 Results based on applied filters

NCCIH Natural Product Early Phase Clinical Trial Award (R33 Clinical Trial Required) (357492)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,050,000
The NCCIH Natural Product Early Phase Clinical Trial Award supports innovative clinical trials of natural products, such as botanicals and dietary supplements, with a strong scientific basis. Applications are encouraged to explore optimal delivery methods and combinations with other treatments. Funding is available for up to three years to assess the impact on target engagement and clinical outcomes, aiming to translate basic science findings into practical clinical applications.
Food Safety Drug Safety

The NIA Genetics of Alzheimer's Disease Data Storage Site (NIAGADS)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIA Genetics of Alzheimer’s Disease Data Storage Site (NIAGADS) aims to create a secure, scalable cloud platform for genetic data related to Alzheimer’s disease. This initiative will enhance data accessibility, promote interoperability, and support rigorous research practices. By facilitating collaboration and providing robust analytical tools, the platform will maximize the scientific impact of AD/ADRD research, aligning with NIH goals for transparent and reproducible science, while addressing recommendations for broad access to high-value datasets.
Dementia & Alzheimer’s Disease

FSR Early Career Fellowship Grant

Foundation For Sarcoidosis Research
Private
United States
US $150,000
The FSR Early Career Fellowship Grant supports early-stage researchers in sarcoidosis, fostering skills and knowledge advancement. With $150,000 over two years, this grant aims to enhance medical care and scientific understanding of the disease. Eligible applicants, including international candidates, must present innovative study proposals and demonstrate a commitment to sarcoidosis research. FSR encourages transitions from fellowships to faculty positions, thereby strengthening academic credentials and promoting impactful research contributions.
Respiratory Diseases & Systems Immune System Diseases

Affiliate Grants - Study Group Activities Fund

American Musicological Society Inc
Private
United States
Up to US $500
The American Musicological Society offers Affiliate Grants to support study group activities with up to $500 in funding, covering no more than 50% of total costs. Applications are accepted twice a year, with deadlines on August 1 and January 15. Only elected representatives of AMS study groups can apply, and groups may receive funding only once in a twelve-month period. Funds must be utilized within a year of the award date.
Music Music Education

Diabetes Research Center (P30 Clinical Trial Optional)

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Up to US $1,000,000
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is announcing a Notice of Funding Opportunity (NOFO) for Diabetes Research Centers (DRCs). These centers aim to foster collaboration among diabetes researchers, enhance preclinical and clinical research, and provide access to specialized resources. Emphasis is on innovative scientific themes and collaborative projects in areas such as Immunology and Artificial Intelligence. Although applications are not currently solicited, potential applicants are encouraged to prepare for future submissions.
Diabetes

Manny Heaton Memorial Scholarship

Posey County Community Foundation
Association/Society
United States
US $2,000
The Manny Heaton Memorial Scholarship honors the legacy of Manny Heaton, a vibrant individual whose life was tragically cut short in April 2023. Established by his father, Tom Heaton, this annual scholarship supports the children of Toyota Motor Manufacturing Indiana (TMMI) employees. Eligible applicants must be graduating seniors with a minimum GPA of 2.0, planning to attend college or technical school, reflecting Manny's dedication and resilience.
Academic Scholarship Programs Education - Higher Education Educational Access & Equity

Bridging the Gap Scholarship

Community Foundation of East Mississippi Inc.
Private
United States
US $1,000

Bridging the Gap Scholarship 

This scholarship was established to honor the memory of Trey Powell and Bridget Horn, who were both Veterans that lost their battle with PTSD to suicide. The Stronger Together Foundation strives to bring awareness to the large number of Veterans who face crises and ultimately commit suicide, as well as provide support to the families left behind. 

Scholarship Total Amount: $2,000.00

  • (Two) $1,000.00 Scholarships will be awarded
Education - Higher Education Military & Veterans Services Mental Health & Psychiatric Diseases

DoW Parkinson’s, Investigator-Initiated Research Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $2,000,000
The FY26 Parkinson’s Research Program Investigator-Initiated Research Award supports innovative, multidisciplinary research projects aimed at advancing the understanding and treatment of Parkinson’s disease. The award encourages collaboration among multiple principal investigators, requiring preliminary data and allowing clinical trials to enhance research outcomes. This initiative is vital for fostering impactful discoveries within the four specified focus areas of the program, ultimately improving patient care and management.
Parkinson’s Disease

Can'd Aid: Crush It Crusade Grant

Can'd Aid
Private
American Samoa, Guam +5 more
US $4,000 - US $10,000
The Can'd Aid: Crush It Crusade Grant empowers nonprofits, local education, and government organizations to enhance recycling efforts. With grants ranging from $3,000 to $8,000, the program supports initiatives that promote recycling at community events, engage volunteers, and foster inclusive outreach. Since 2014, over 125 organizations have benefited from this funding, driving impactful change through community engagement and environmental stewardship.
Waste Management

Brothers Helping Brothers: Equipment Grants

Brothers Helping Brothers
Private
United States
Unspecified amount in in-kind support
Brothers Helping Brothers is a 501c3 non-profit organization dedicated to providing essential tools and equipment to small and rural fire departments. Founded in 2014 after a tragic loss, the organization has raised over $20,000 to support fire services. They grant financial assistance to eligible fire and EMS organizations across the U.S. with a focus on enhancing safety and operational capability. Their mission continues to grow as they research and address the pressing needs of emergency services.
Firefighting & Fire Prevention Emergency Medical Care & Services

Alzheimer’s Association Research Grant For All (AARGA) Program

Alzheimer's Association
Private
United States
US $70,000 - US $200,000
The Alzheimer’s Association Research Grant For All (AARGA) Program supports early-career investigators in their first seven years as independent researchers. This grant aims to fund projects that develop preliminary data and test new hypotheses in Alzheimer’s and related dementia research. Areas of interest include disease mechanisms, biomarker development, and health equity. Applications are welcome from both U.S. and international researchers, fostering innovation and collaboration in the fight against dementia.
Dementia & Alzheimer’s Disease

Greater Minnesota Housing Infrastructure Grant Program

Minnesota Housing Finance Agency
State/Local Government
Aitkin County, Minnesota, Becker County, Minnesota +80 more
Up to US $500,000

Greater Minnesota Housing Infrastructure Grant Program

Grant funds can be used to cover up to 50% of capital costs of physical public infrastructure necessary to support a qualifying housing development. This may include sewers, water supply systems, utility extensions, streets and more, necessary to support single-family, multifamily, homeownership and rental housing development.

Grants are generally limited to:

  • $40,000 per lot for one to four units
  • $180,000 per lot for multifamily housing (five or more units/building)
  • $60,000 per manufactured housing lot
  • No more than $500,000 to any grantee or project over a two year period.

Applicants’ matching funds may include in-kind contributions, such as donation of land.

Equitable & Affordable Housing

The Simply Organic Giving Fund Grant Program

Simply Organic
Corporate
Canada, United States
US $30,000 - US $100,000
The Simply Organic Giving Fund Grant aims to combat food insecurity in the U.S. and Canada by providing access to nutrient-dense organic food for those in need. Since its inception, the fund has supported various initiatives, including training centers for organic agriculture and community food projects. With a focus on sustainable practices, the grant program seeks to empower communities and improve food access for vulnerable populations, ensuring that healthy, organic options are available to all.
Food Security

Affiliate Grants - Chapter Activities Fund

American Musicological Society Inc
Private
United States
Up to US $500
The Affiliate Grants - Chapter Activities Fund, offered by the American Musicological Society, provides financial support for chapter activities and programs. Each chapter can request up to $500, covering no more than 50% of total costs. Applications are accepted semi-annually, with deadlines of August 1 for summer and January 15 for winter. Notably, chapters can only receive funding once per twelve-month period, ensuring fair distribution of resources.
Music Music Education Nonprofit Growth & Development

Jazz Road Tours Grants

South Arts, Inc.
Private
American Samoa, Guam +5 more
Up to US $15,000
Jazz Road Tours Grants provide financial support for emerging and mid-career jazz artists to develop tours across communities in the U.S. Grants up to $15,000 facilitate three-to-six site tours, focusing on underserved areas. This program, funded by the Doris Duke Charitable Foundation and the Mellon Foundation, aims to enhance artists' income opportunities while promoting jazz in diverse venues. Applications are encouraged from individual artists, with deadlines throughout 2024 and 2025 for various tour periods.
Music Festivals

MOORE Equity in Mental Health Community Grants Program

American Psychiatric Association Foundation
Private
United States
US $10,000
The MOORE Equity in Mental Health Community Grants Program, initiated by the American Psychiatric Association Foundation, aims to enhance mental health services for young people of color. With grants up to $10,000 over two years, it supports community organizations addressing mental health and substance use inequities. Eligible applicants include non-profits with a focus on culturally relevant care and sustainable solutions. The program fosters collaboration and awareness through innovative initiatives aimed at improving access to essential mental health services.
Mental Health & Psychiatric Diseases Addiction & Substance Use Disorders Health Care Access & Delivery

K–12 Educators Grants in American Music

American Musicological Society Inc
Private
United States
US $500
The K–12 Educators Grants in American Music, offered by the American Musicological Society, provides $500 awards to K-12 educators with an interest in American music to attend the Teaching Music History Conference. This grant supports educators in engaging with historical pedagogy through workshops and networking opportunities. Participants will explore American music's significance while developing actionable lesson plans, fostering connections among educators and researchers committed to enhancing music education.
Music Education - K through 12 Teacher Development & Training

Zink Family Scholarship

Marshall Community Foundation
Private
United States
Unspecified amount

Marshall Community Foundation

The Marshall Community Foundation is a partnership of endowed funds established by individuals and organizations. A Board of Trustees, comprised of local community leaders, invest the pooled endowments. Income generated is then available for grants that address charitable needs in our community. Staff and trained volunteers monitor the grants to ensure fulfillment of the grant agreements.

The full circle of philanthropy is poetry in motion. The Foundation receives your gifts, grants to local non-profits, who in turn, give back by providing services to the community. Truly, the Foundation is all about improving the quality of life and making this a better place to live, work and raise a family.

Zink Family Scholarship

A scholarship awarded to residents of Marshall and surrounding townships pursuing an education or advanced training in skilled trades, as defined by the Committee and reflective of current industry needs, including but not limited to the fields of:

  • healthcare technician,
  • agriculture,
  • information technology,
  • manufacturing,
  • construction or
  • automotive.
Career / College Preparation Academic Scholarship Programs Vocational & Trade Education

FOXG1 Scientific Research Project Grants

FOXG1 RESEARCH INC
Private
Countries
Unspecified amount

About

What is FOXG1 Syndrome?

FOXG1 syndrome is a rare genetic neurodevelopmental disorder caused by a mutation in the FOXG1 gene. FOXG1 gene is one of the first and most important genes for early brain development and when impaired, causes developmental disabilities as well as medical complexities, including epilepsy.

Every child born with FOXG1 syndrome is unique as FOXG1 manifests as a spectrum where symptoms and severity vary between individuals. Our patient data shows characteristics of children with FOXG1 syndrome include: non-speaking, non-ambulatory, experience seizures, feeding problems, cortical vision impairment, movement disorders, and developmental delays. Less-severely-affected FOXG1 children often present with (ASD) Autism Spectrum Disorder as FOXG1 is an autism related gene. FOXG1 syndrome is found equally among both females and males and is geographically more prevalent where diagnostic testing is more advanced. 

Our Story & Mission

When our children were diagnosed with FOXG1 syndrome, we were told there was nothing we could do. No treatments, no concerted research underway, no roadmap. Just a devastating diagnosis for a disorder few had ever heard of.

But we refused to accept that. 

Research Assets & Grants

FOXG1 Scientific Research Project Grants

The FOXG1 Research Foundation is providing grants to scientists to deepen the understanding of the biology of FOXG1 with the goal of identifying innovative therapeutic strategies and finding a cure.

For the next few years, these are the strategic focus areas:

  • Experiments designed to understand when, where, and levels of FOXG1 needed for normal brain development in mice
  • Experiments designed to understand the biophysical properties of FOXG1 mutations
  • Experiments designed to gain insights into the molecular and cell biological pathways regulated by FOXG1  
Rare Diseases Neurological Diseases & Disorders

Building Capacity for Communicating Impact Learning Community RFA

Association of State and Territorial Health Officials (ASTHO)
Association/Society
United States
Unspecified amount

Building Capacity for Communicating Impact Learning Community RFA

Learn how to communicate about Public Health Infrastructure Grant impact through a new community of practice! Through peer learning, technical assistance, and practical tools, participating teams will build strategic leadership and communications skills to more effectively translate public health achievements into compelling messages for key audiences. All directly funded PHIG recipients (big-city, county, state/territory-level governmental public health professionals) are eligible to apply.

Health Care Access & Delivery Medical Education & Professional Training Health Disparities & Social Determinants of Health

Brees Dream Foundation Contribution Grant

Brees Dream Foundation
Private
United States
Unspecified amount
The Brees Dream Foundation Grant aims to enhance the lives of cancer patients while providing essential care, education, and opportunities for children and families in need. With the support of generous donors and partners, the Foundation is dedicated to advancing cancer research and offering vital resources to those facing challenges. This commitment reflects a profound dedication to improving quality of life and fostering hope in communities.
Cancer / Oncology Child Welfare Services Youth Services

DoW Bone Marrow Failure, Resource Development Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $1,250,000
The FY26 Bone Marrow Failure Research Program's Resource Development Award aims to create a multiomic atlas from human bone marrow failure samples. This resource will be open-access, providing essential data for researchers and clinicians to enhance their understanding of bone marrow failure diseases. A comprehensive Data Resource Sharing Plan is required to ensure timely availability of the developed resource, fostering collaboration within the scientific community.
Skeletal Diseases Myeloma

Accreditation Sustainability Learning Community RFA

Association of State and Territorial Health Officials (ASTHO)
Association/Society
United States
Unspecified amount

Accreditation Sustainability Learning Community RFA

The Association of State and Territorial Health Officials (ASTHO), through the Public Health Infrastructure Grant (PHIG), is currently accepting applications for participation in a learning lab that will foster health department capacity to build a sustainable public health accreditation culture within their agencies. This opportunity is open to applicants from direct PHIG awardees at the state-, big city-, and county-level.

Health Care Access & Delivery Health Disparities & Social Determinants of Health Medical Education & Professional Training

Interventions to Address Disparities in Liver Diseases and Liver Cancer (R01 - Clinical Trials Optional) (357550)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This initiative aims to support research interventions targeting disparities in liver diseases and liver cancer among underserved populations in the U.S. It encourages innovative approaches to reduce health inequities and improve health outcomes. The funding opportunity is available through various deadlines for both standard and renewal applications, promoting multi-level strategies to address these critical health issues effectively.
Cancer / Oncology Liver Disease Health Disparities & Social Determinants of Health

Brothers Helping Brothers: Backing Safety Initiative Grants

Brothers Helping Brothers
Private
United States
Unspecified amount in in-kind support
The Brothers Helping Brothers initiative aims to provide essential equipment to small fire departments and EMS organizations in the U.S. Established in 2014, the program offers grants to eligible agencies serving communities with populations under 10,000. With a focus on tools like wireless backup cameras, the organization strives to enhance safety and operational efficiency for first responders. Through community support, they have raised significant funds to assist in this critical mission.
Firefighting & Fire Prevention Emergency Medical Care & Services

AHRF: Birtman Grant

American Hearing Research Foundation
Private
United States
Up to US $75,000
The AHRF Birtman Grant provides up to $75,000 for one year of research focused on hearing and balance disorders related to the inner ear. This grant encourages both basic and clinical studies, covering direct costs such as staff salaries and research equipment. Applicants must hold relevant advanced degrees and be affiliated with a U.S. university or hospital. An alternative budget option of $50,000 is available, enhancing eligibility for Regular grants if not awarded the Birtman Grant.
Hearing Disorders & Audiology

RRF Pilot Study Grants

Retina Research Foundation
Private
United States
Unspecified amount

Retina Research Foundation

Across the nation, there were only a handful of voluntary groups with the will and the means to tackle retinal disdorders. Retina Research Foundation, established in 1969, was one of those organizations. By the 1980s, RRF had become a voice for retina research in an effort to reduce the incidence of retinal disease, which was fast becoming the leading cause of blindness in developing countries.

Undaunted, the Foundation steadily raised funds each year for vision scientists who were nationally recognized for their work in retina research. Government funding for eye research increased dramatically, and the field of retina research matured. As this body of knowledge grew, RRF programs were expanded to include major awards that recognize established retina scientists and contribute to their ongoing research. The Foundation also developed scientific exchange programs to disseminate knowledge of the dramatic advances that were being made in the laboratory.

RRF Pilot Study Grants

The mission of the Retina Research Foundation is to reduce retinal blindness worldwide by funding programs in research and education. As a public charity, RRF raises funds from the private sector and the investment of its endowment funds.

RRF is currently welcoming pilot study grant applications for the 2027 grant period. Each grant application must be signed by the principal investigator and either their Department Chair or Dean of Research.

Eye Diseases & Disorders Vision Impairment Care & Services

Financial Assistance Grants in South Dakota Highlights

Looking for financial assistance grants in South Dakota?


Read more about each grant below or start your 14-day free trial to see all financial assistance grants in South Dakota recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Financial Assistance Grants in South Dakota

Grant Availability

How common are grants in this category?

Uncommon — grants in this category are less prevalent than in others.

100+ Financial Assistance Grants in South Dakota grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

30 Financial Assistance Grants in South Dakota over $25K in average grant size

23 Financial Assistance Grants in South Dakota over $50K in average grant size

23 Financial Assistance Grants in South Dakota supporting general operating expenses

91 Financial Assistance Grants in South Dakota supporting programs / projects

2,000+ Grants on Instrumentl focused on Human & Social Services

400+ Grants on Instrumentl focused on Disaster Relief / Humanitarian Aid

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Financial Assistance grants in South Dakota?

Most grants are due in the first quarter.

Q1
34.7%
Q2
24.6%
Q3
19.8%
Q4
21.0%

Typical Funding Amounts

What's the typical grant amount funded for Financial Assistance Grants in South Dakota?

Grants are most commonly $10,000.

$250 $250 Min.
$10,000 $10 K Median
$89,650 $89.7 K Average
$1,250,000 $1.3 M Max.

Average Grant Size

What's the typical amount funded for South Dakota?

Grants are most commonly $110,621.

$110,621

Total Number of Grants

What's the total number of grants in Financial Assistance Grants in South Dakota year over year?

In 2024, funders in South Dakota awarded a total of 6,460 grants.

2022 6,268

2023 6,140

2024 6,460

Top Grant Focus Areas

Among all the Financial Assistance Grants in South Dakota given out in South Dakota, the most popular focus areas that receive funding are Education, Human Services, and Philanthropy, Voluntarism & Grantmaking Foundations.

1. Education

2. Human Services

3. Philanthropy, Voluntarism & Grantmaking Foundations

Funding Over Time

How is funding for Financial Assistance Grants in South Dakota changing over time?

Funding has increased by 17.48%.

2022 $638,830,994

2023 $606,495,212
-5.06%

2024 $712,509,384
17.48%

South Dakota Counties That Receive the Most Funding

How does grant funding vary by county?

Minnehaha County, Lake County, and Pennington County receive the most funding.

County Total Grant Funding in 2024
Minnehaha County $176,653,145
Lake County $117,647,066
Pennington County $90,630,616
Brookings County $75,457,854
Todd County $56,559,538