Best Foundation Grants for Nonprofits in South Dakota

The National Institutes of Health (NIH) is continuing support for the Network for Excellence in Neuroscience Clinical Trials (NeuroNEXT), which focuses on clinical trials and biomarker validation studies for neurological disorders. This initiative aims to foster innovation in neurotherapeutics by providing essential infrastructure and expertise. The program encourages the establishment of Clinical Coordinating Centers (CCC) and Data Coordinating Centers (DCC) to enhance collaborative efforts. Note that applications are not currently being solicited.

The Bonnie Plants 3rd Grade Cabbage Grant Program inspires young students to cultivate a love for gardening by providing free oversized cabbage plants to 3rd grade classrooms across the continental U.S. Initiated in 1996, the program encourages hands-on learning about where food comes from. Each year, students compete for a $1,000 prize awarded to the best cabbage grown, fostering excitement and education about agriculture. This initiative not only promotes environmental awareness but also engages students in practical science.

The AAAS Early Career Award for Public Engagement with Science recognizes outstanding early-career scientists and engineers for their significant contributions to public engagement in science. Established in 2010, the award includes a $5,000 prize, a plaque, and recognition at the AAAS Annual Meeting. Eligible nominees must be actively conducting research in STEM fields and demonstrate engagement beyond their job responsibilities, with one awardee chosen annually.

About Us

We are one of over 900 community foundations in the US. We serve the 7 county Pee Dee region of South Carolina. Our mission is to improve the quality of life in our area of the state.

Who We Are

Eastern Carolina Community Foundation, founded in 2006, is the newest community foundation in South Carolina. We have a permanent endowment to meet the changing needs of the Pee Dee.

• We foster philanthropy.
• We build resources for nonprofits.
• We support our local communities.

FBi Construction Scholarship

FBi Construction created a scholarship fund at ECCF in 2017 to encourage students to enter the construction industry. This interest stems from a strong belief in education and a commitment to improve the quality of life where they do business. This scholarship funding will improve the talent pool which maintains FBi’s commitment to excellence.

The DEVCOM Analysis Center Broad Agency Announcement invites research proposals to support the U.S. Army's mission of informed modernization through data-driven analysis and technology development. Open until January 4, 2028, it seeks innovative whitepapers and proposals from various organizations to enhance Army capabilities and technologies. This initiative aims to foster significant advancements that align with national security needs and drive scientific exploration in applied research and advanced technology.

Mission: A non-profit, charitable, Private Foundation established in 1959 by the Long family to support local charities, schools, education events and general community needs.

Grants

Our approach to grant requests focuses on fostering local neighborhood vitality and excellence. The John F. Long Foundation supports local non-profit organizations that promote this objective. The Foundation looks for groups who are working to help themselves, help their own communities, and help others like themselves through self-empowering, community organizing efforts. To be eligible for consideration, the grant request must meet the following criteria:

• Funds’ use must have measurable benefits
• Your organization must have good management, a solid financial background, well-established administration policies and Board of Directors
• The grant request must be precise and complete, providing necessary detail
• The Foundation Questionnaire is to be completed in its entirety
• The grant request amount and time frame must be clearly communicated, i.e. one-time grant, ongoing support, or special project
• If your request is for a particular event or program, providing a budget is always helpful
• Requests for grants of $1,000.00 or more, as well as groups we have not funded within the past two years, must: (i) Provide financial reports/statements for past and current fiscal year; (ii) Provide a list of past donors going back no more than two years.

About Borealis Philanthropy

Borealis Philanthropy is a philanthropic social justice intermediary that works to resource grassroots leaders and social justice movements for transformative change. We help funders expand their reach and strengthen their impact through donor collaboratives that support a variety of issues, communities, and movements. Borealis is home to nine donor collaboratives, including the Disability Inclusion Fund and Disability x Tech.

DIF x Tech Fund

For the Disability Inclusion Fund at Borealis, part of our efforts for disability rights and justice includes the ways disability and technology are working towards shared goals in our movements. The DIF x Tech initiative, supported by the Ford Foundation’s Technology & Society Program and the MacArthur Foundation’s Technology in the Public Interest, invites proposals that are working to bring about transformational change at the intersections of disability, justice, and technology

About the Disability Inclusion Fund and DIF x Tech

The Disability Inclusion Fund (DIF) supports U.S.-based groups run by and for people with disabilities to lead transformational change. The Fund is supported by donors including the Presidents’ Council on Disability Inclusion in Philanthropy, which is comprised of foundation presidents who are committed to disability inclusion as part of improving diversity, equity, and inclusion within philanthropy.

Part of the efforts of disability rights and justice includes the ways disability and technology are working towards shared goals in our movements. This newly launched initiative is housed at the Disability Inclusion Fund (DIF) and supported by Ford Foundation’s Technology & Society Program and the MacArthur Foundation’s Technology in the Public Interest. 

DIF x Tech Fund Values

All Disability x Tech award decisions will align with the DIF guiding values. The DIF guiding values are:

• Participation: Movement funding accountable to the disability rights movement. Those impacted by injustice/exclusion should be involved in strategies to advance justice/inclusion.
• Intersectionality: Acknowledging that disabled people have multiple and intersecting social and political identities that can influence their ability to have access and inclusion including race, gender identity, class, sexual orientation.
• Radical inclusion: Deeply committed to removing barriers and ensuring access so that those most affected by intersecting identities can participate, valuing lived experience.
• Leadership of those most impacted by ableism: Emphasis is given to organizations led by people subject to systemic bias and impacted by underrepresentation, particularly disabled people of color, queer, gender nonconforming and women with disabilities.
• Cross-movement solidarity: Intentional focus on collaboration and bridge- building amongst disability justice activists and across movements.
• Sustainability: Resources and tools that support the growth of grassroots disabled-led organizations, and expand operational capacities for ongoing movement building. 

What we fund

We invite proposals that are at the nexus of technology, disability rights and justice. This opportunity may be a good fit for your organization, if you are doing work in any of these areas below:

• Disabled people sharing technical skills and knowledge with others in the community.
• Disabled people leading policy, rights, and disability justice activism work related to tech. 
• Disabled people participate in all stages of the design and development of new tech that will enrich lives of people with disabilities.
• Enabling collective and equitable access to digital infrastructure. 
• Expanding the participation, leadership, and thought partnership of overlooked and under-resourced people with disabilities in all areas of the technology sector.
• Partnerships between disability-focused engineering design labs and maker spaces within schools, centers for independent living, or local nonprofit organizations.
• Permissible Policy Work:
  • We may support nonpartisan policy education and advocacy related to disability and technology. Any lobbying must remain within applicable 501(c)(3) limits and Borealis grant restrictions.

Innovation in Religion and Spirituality Seed Grants Call for Proposals

The Religion and the Public Sphere program at the Social Science Research Council aims to foster research on the wider implications of new forms of religious and spiritual life. This program is offered with the support of the Luce Foundation, the John Templeton Foundation, and the Templeton World Charity Foundation.

Overview

In recent years, scholars have noted that religious and spiritual life is being substantively reshaped. “Innovation” is one way of framing these changes, but it remains a partial and contested analytic lens, and is popularly associated with the sudden emergence of a “new” element introduced into an otherwise static tradition. Scholarship on religion and spirituality, however, points to a more complex set of processes. The essays in an ongoing forum for The Immanent Frame have set out some initial parameters of these dynamics: rather than invention ex nihilio, what we often see is the strategic recombination of existing elements within a broader context of social, political, and cultural change.

Research Themes

This request invites proposals that examine the dynamics of religious and spiritual change that fall within the frame of “innovation.” Possible topics include, but are not limited to: 

• Explorations of innovations within transnational or diasporic religious and/or spiritual communities within the United States, particularly related to the circulation of ideas and culture from or to the Global South.   
• Gendered knowledge of innovation. 
• Studies of the process by which an innovation attains—or does not attain—legitimacy, relevance, or authority within a given community or institution. 
• The relationship between contemporary economic conditions—poverty, economic insecurity, and competitive pressures for time and money—and innovations in religion and spirituality. 
• Historical studies of innovations in religion and spirituality; the creation, reception, transformation, and longevity of an innovation over time.  
• Civic participation and the social mobilization of new or innovative religious identities, as well as the reinterpretation of religious or spiritual traditions or ideas in the service of particular political or ideological projects.

Program Terms 

The program offers research support over a period of up to 6 months. The grant funds will be up to $10,000 per award.

The Eleanor Campbell Charitable Fund offers competitive scholarships to high school seniors and current college students from the Deering, Hillsborough, and Weare areas. With a history of over $900,000 awarded, the fund emphasizes academic achievement, financial need, and community involvement. Scholarships are available for full-time post-secondary education, with the potential for renewal based on continued eligibility. Announcements of winners occur during high school graduation ceremonies, ensuring recognition of their hard work and dedication.

The Louisville Institute offers the Grant for Researchers to support academic research in North American Christianity and related fields. Grants of up to $55,000 are available for sabbatical leaves, research projects, and necessary resources. This flexible program combines previous grants to meet contemporary academic needs. Applicants can apply individually or as teams of up to three, provided they are based in the U.S. or Canada. Projects bridging scholarship and church life are of particular interest.

The Innovative Research in Cancer Nanotechnology (IRCN; R01 Clinical Trial Not Allowed) program invites applications focused on revolutionary breakthroughs in cancer biology and oncology through nanotechnology. Projects should tackle significant challenges in these fields while emphasizing mechanistic studies of nanomaterials and devices. The aim is to enhance understanding of their interactions with biological systems, particularly in delivering nanoparticles to cancer targets, thus laying the groundwork for future nanotechnology-based interventions.

The ACI Foundation's Tribute to the Founders Fellowship supports graduate students in construction, design, education, or materials. Awardees receive a $10,000 educational stipend, recognition in Concrete International magazine, and travel expenses to two ACI conventions. This fellowship aims to foster the next generation of concrete industry leaders through education and mentorship, while also encouraging personal development and career readiness through a structured internship program.

The National Cancer Institute (NCI) invites applications for the Toward Translation of Nanotechnology Cancer Interventions (TTNCI) program. This funding opportunity focuses on advanced pre-clinical research aimed at developing nanotechnology-based cancer diagnostics and therapeutics. TTNCI awards will support the maturation of innovative nanomedicines using nanoparticles and nano-devices, enhancing cancer treatment efficacy. Successful projects will progress towards further NCI translational programs, such as the NExT initiative.

The Greenwall Foundation invites proposals for its Bridging Bioethics Research & Policymaking Grants, aimed at integrating bioethics into policy without funding academic research. This initiative addresses ethical dilemmas arising from healthcare advancements, encouraging innovative project ideas at all governmental levels. Grants up to $50,000 will prioritize projects with smaller budgets and shorter timelines. Collaborations with diverse expertise beyond academia, including policymakers, are encouraged to effectively bridge research and policy.

The Patient-Centered Outcomes Research Institute (PCORI) is funding Cycle 3 to enhance patient-centered comparative clinical effectiveness research (CER). This initiative targets critical methodological gaps, focusing on improving the use of artificial intelligence, study design, data research networks, and ethical protections. By addressing these areas, PCORI aims to strengthen the quality of evidence in CER, thus promoting better outcomes in healthcare decision-making.

The Olney Medal, established in 1944 by the American Association of Textile Chemists and Colorists (AATCC), honors exceptional achievements in textile chemistry and related fields. It recognizes significant contributions to the development of chemical processes and agents in textile manufacturing. Open to all AATCC members for nominations, the award emphasizes the importance of innovation and public recognition in advancing textile sciences, a legacy of its founder, Dr. Louis Atwell Olney.

Committee of 100 Academic Scholarship

Awards:

• One time award of $5,000.

The Greenwall Foundation invites nominations for the 2025 Bernard Lo, MD Award in Bioethics, a prestigious $25,000 prize recognizing outstanding contributions to bioethics. This award highlights exceptional mentorship in bioethics, celebrating individuals who support rising professionals across diverse sectors, including academia, government, and public health. Nominations can be made by mentees and colleagues, fostering an inclusive recognition of mentorship excellence. Renominations are encouraged, but self-nominations are not allowed.

The Patient-Centered Outcomes Research Institute (PCORI) is offering funding up to $750,000 for studies aimed at addressing critical methodological gaps in patient-centered comparative clinical effectiveness research. This initiative focuses on enhancing the quality of evidence in clinical research by prioritizing areas such as artificial intelligence, study design improvements, support for data research networks, and ethical considerations. Successful proposals will contribute to advancing research methodologies and improving patient outcomes.

The BRAIN Initiative aims to advance innovative neurotechnologies by funding early-stage clinical studies for devices that record or stimulate the human central nervous system. This initiative encourages collaborations between clinical researchers and device manufacturers to facilitate groundbreaking studies. By addressing the challenges of obtaining safety and utility data, this program supports both non-invasive and significant risk devices, providing essential insights into their functionality and design. Applications are currently not being solicited, allowing time for meaningful project development.

Self-Defense Grants for MMIR Day

Facilitators, educators, organizers — May 5th is the Day of Awareness for Missing & Murdered Indigenous Women, Girls and Relatives. In honor of that day, we are offering mini grants to host a self-defense workshop for Indigenous girls and gender-expansive youth.

Why self-defense?

• Native women are murdered at 10x the national rate
• 84% experience violence in their lifetime
• Over 5,700 Native girls go missing each year

We also name the invisible crisis:

• Indigenous people from Mexico & Central America (Maya, Nahua, Zapotec, Mixtec, Lenca, and others) living in the U.S. face detention, deportation, and disappearances that are rarely counted in MMIR data.
• When a Tzotzil 18 year old like Royer Perez Jimenez dies in ICE custody, the silence is deafening.

Self-defense must include all Indigenous relatives.

XCNC has:

• $500 mini grants for stipends, space, supplies, and translation.

What we ask:

• Plan a workshop between May 5–31, 2026, rooted in community care.

The Patient-Centered Outcomes Research Institute (PCORI) Funding Announcement aims to enhance methods for conducting patient-centered comparative clinical effectiveness research. This initiative seeks to address critical methodological gaps, focusing on improving the use of artificial intelligence in clinical research, study design, data research networks, and ethical protections in patient-centered CER. With a budget of up to $750,000, successful proposals will contribute to the quality and strength of evidence generated in CER studies.

Scholarships are available to graduating high school seniors. Applications are accepted from mid-November until mid-March. Scholarship award recipients will be announced at the high school awards ceremony. 

Beatrice Reynolds Memorial Scholarship

Established by the late Ira T. Reynolds in memory of his late wife to assist a Susquehanna Community School District graduate who will major in education or teacher training. Scholarship is provided in four equal installments as long as the recipient remains a student in good standing.

The Ilpo Martikainen Audio Visionary Scholarship, provided by the Audio Engineering Society Educational Foundation, supports U.S. graduate students dedicated to advancing audio technology. This scholarship honors the legacy of Dr. Martikainen, founder of Genelec, who significantly contributed to loudspeaker innovation. Eligible students must have completed an undergraduate degree and demonstrate a commitment to audio engineering. Grants typically range from $2,000 to $5,000, paid directly to the student's graduate school.

The Dressage Foundation

The Dressage Foundation is a 501(c)(3) non-profit, tax-exempt organization, whose mission is to cultivate and provide financial support for the advancement of dressage in the United States.

In 1989, Lowell Boomer founded The Dressage Foundation (TDF) with a vision: to empower dressage across the country. Since then, we've awarded millions of dollars in grants, helping people across our sport, and across the country, achieve their dreams. From grassroots initiatives to high-performance endeavors, we aim to create a strong, inclusive, and vibrant dressage community.

We strive to cultivate dressage excellence by reducing some of the financial barriers of dressage training and education, and we believe that every aspect of our sport deserves help.

George Williams Young Professional Fund

The George Williams Young Professional Fund supports dressage professionals, ages 25-35, who are committed to the sport and have established businesses as instructors and trainers.   

The George Williams Young Professional Fund was established in 2018 to honor his lifelong commitment to dressage. Applicants should have a strong desire to participate in continuing education opportunities, in order to provide higher-quality instruction to their students. 

The NABG Scholarships support full-time undergraduate and graduate students in Geoscience programs at accredited institutions, with over $300,000 in funding raised through donations and events. Candidates must exhibit academic excellence, aiming to equip them for future careers in the geosciences. This initiative, backed by the National Association of Black Geoscientists, fosters diversity and prepares the next generation of professionals in the field.

This grant aims to enhance safety and health in U.S. mining operations through research in automation, robotics, and intelligent systems. It addresses critical issues like emergency communication and self-escape reliability while supporting the development of field-ready solutions. By leveraging advanced technologies, the initiative seeks to improve miner safety and health, reduce hazardous exposures, and foster community engagement. Applicants must be U.S. academic institutions with accredited mining programs, linking project goals to documented health burdens.