Best Grants for 501(c)(3) in South Dakota

About Samba RecoverySamba Recovery is dedicated to empowering individuals recovering from alcoholism and drug addiction by restoring confidence and fostering resilience. Through a foundation of compassion, support, and holistic care, we guide individuals toward renewed health and wellness, meaningful relationships, and the discovery of their inner strengths—assisting them to achieve their fullest potential.Hope for Addiction ScholarshipSamba Recovery’s Hope for Addiction Scholarship is an annual $1,000 award dedicated to encouraging more young people to join the fight against addiction by pursuing degrees that directly support individuals and families affected by substance use disorders.

We welcome applications from all eligible students, with special encouragement for those who are in recovery themselves or who have been impacted by addiction within their families.Application requirements:

• Proof of college enrollment or acceptance
• Pursuing a degree with the goal of working with individuals and/or families impacted by addiction
• Completed application form
• An original 500 to 1000 word essay on how you are planning to use your degree to help individuals and families struggling with addiction, and why helping those affected by substance use disorder is important to you

The See, Test & Treat Grant offers vital funding for cancer screening and health education programs targeting medically underserved communities. This pathologist-led initiative aims to reduce healthcare barriers, empower preventive care, and connect patients with local resources. Eligible organizations can apply for up to $50,000 over three years, fostering sustainable health improvements. The program emphasizes same-day results for screenings and culturally appropriate education, ensuring equitable access to essential healthcare services.

The Walking Classroom Grant Program, offered by the Alliance for a Healthier Generation, enables classroom teachers in public schools to receive donated materials for their students. This innovative program promotes physical activity while maintaining instructional time through engaging podcasts. Ideal for grades 3-8, it enhances cognitive function and retention. Schools with the greatest need, both socioeconomically and academically, are prioritized, ensuring that all students can benefit from this unique educational approach.

The NEA Federal Rescue Implementation Network Grant provides up to $100,000 per year for two years to state affiliates for hiring a coordinator to implement the American Rescue Plan in support of public education. This funding is specifically for backfilling a position that must remain filled for at least ninety days, ensuring effective oversight of federal recovery initiatives within the affiliate.

The T32 Training Program for Institutions That Promote Diversity aims to increase the involvement of individuals from underrepresented backgrounds in research related to cardiovascular, pulmonary, hematologic, and sleep disorders. This initiative seeks to support institutions dedicated to serving health disparity populations, ensuring they develop robust training programs. While trainees cannot lead independent clinical trials, they can gain valuable experience under the guidance of mentors, ultimately contributing to improved health outcomes for underserved communities.

About Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Who we are and our impact

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Eosinophilic esophagitis

Help with healthcare costs for eosinophilic esophagitis

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

About the disease

Eosinophilic Esophagitis (EoE) is a disorder of the esophagus and is increasingly recognized as a major cause of swallowing difficulties in children and adults. It is a chronic disease of the immune system and can be triggered by a food allergy, acid reflux, or an airborne allergy. An allergic trigger causes the immune system to overact which causes many white blood cells, or eosinophils, to collect in the esophagus. This causes the esophagus to become inflamed and not contract properly. The esophagus can also narrow and develop rings or abscesses. This condition can become worse over time.

About Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Who we are and our impact

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Multiple sclerosis (MS)

Help with healthcare costs for Multiple sclerosis (MS)

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

About the disease

Multiple sclerosis (MS) is a potentially disabling disease of the central nervous system in which the insulating covers of the nerve cells in the brain and spinal cord are damaged. MS is a chronic disease that affects the nervous system.

About Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Who we are and our impact

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Multiple sclerosis (MS) health equity

Help with healthcare costs for multiple sclerosis (health equity)

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

Health Equity Funds offer help to eligible patients living in areas identified as having increased social and financial needs, as well as higher rates of chronic conditions. Eligibility is determined in part by home address zip code. 

About the disease

Multiple sclerosis (MS) is a potentially disabling disease of the central nervous system in which the insulating covers of the nerve cells in the brain and spinal cord are damaged. MS is a chronic disease that affects the nervous system.

The Indigenous Scholarships: Arts Fund facilitates artistic development for Aboriginal Australian, Torres Strait Islander, Native American, Alaskan Native, and Native Hawaiian artists. Offering up to $5,000, it supports projects in each other's countries, with applications due in March and September. Since 2002, over $1 million has been awarded to more than 500 artists, fostering cultural exchange and growth in the arts between Australia and the USA.

The Wild Felid Legacy Scholarship, established by the Wild Felid Research and Management Association in 2009, supports graduate students researching wild felids in the Western Hemisphere. It awards one to three scholarships ranging from $1200 to $1500, based on financial need and research impact. To date, 38 scholarships totaling over $44,000 have been awarded in memory of dedicated biologists who contributed to wildlife conservation. Recipients are recognized in the WFA's newsletter, the Wild Felid Monitor.

The Rural Maternity and Obstetrics Management Strategies Program (Rural MOMS) aims to enhance access to maternity and obstetrics care in rural areas through collaborative networks. Funded by the US HHS: Health Resources & Services Administration (HRSA), this initiative focuses on innovative strategies to improve healthcare delivery for mothers and infants in underserved regions, ensuring that quality care is accessible where it is needed most.

The Congenital Sucrase-Isomaltase Deficiency Fund, managed by the HealthWell Foundation, aims to alleviate financial burdens for underinsured patients suffering from this genetic disorder. By providing assistance with prescription drugs and treatment costs, the fund ensures that vital medications are accessible, allowing patients to manage their condition effectively. In 2024, the Foundation is expected to award over $1.2 billion in grants, showcasing its commitment to enhancing healthcare access for those in need.

Oregon Department of Forestry

Vision: Complex and resilient forest ecosystems that endure and adapt.

Mission: To protect and promote resilient forests that benefit all Oregonians.

US Dept. of Transportation Grant - Safe Streets and Roads for All (SS4A) Grant Program

The purpose of this Notice of Funding Opportunity is to solicit applications for Safe Streets and Roads for All (SS4A) grants.

Funds for the fiscal year (FY) 2026 SS4A grant program are to be awarded on a competitive basis to support planning, infrastructural, behavioral, and operational initiatives to prevent death and serious injury on roads and streets involving all roadway users, including pedestrians; bicyclists; public transportation, personal conveyance, and micromobility users; motorists; and commercial vehicle operators.

The SS4A Grant Program includes: 1) Planning and Demonstration Grants; and 2) Implementation Grants.

Planning and Demonstration Grants

Planning and Demonstration Grant Eligibility Requirements

Eligible activities for a Planning and Demonstration Grant include: develop a new Action Plan, conduct supplemental safety planning to update an existing Action Plan, or carry out safety demonstration activities to inform the development of or update to an Action Plan.

These activities may be bundled in any combination, provided that the requirements in this Notice are met. DOT encourages complementary but distinct activities, including but not limited to safety demonstration activities that will help inform the development of an Action Plan. Any applicant that meets the eligibility requirements may apply for a Planning and Demonstration Grant to develop an Action Plan. 

• Expected number of awards: 400 to 700

The Measurement and Evaluation Graduate Student Award, offered by SHAPE America, aims to support graduate students specializing in psychomotor measurement and evaluation. This scholarship assists with professional expenses, ensuring candidates can focus on their studies. Eligible applicants must be current SHAPE America members and pursuing relevant master's or doctoral degrees. The award prioritizes those who have completed their first year of study, promoting excellence in health and physical education across the U.S.

Oregon Department of Forestry

Vision: Complex and resilient forest ecosystems that endure and adapt.

Mission: To protect and promote resilient forests that benefit all Oregonians.

US Dept. of Transportation Grant - Safe Streets and Roads for All (SS4A) Grant Program

The purpose of this Notice of Funding Opportunity is to solicit applications for Safe Streets and Roads for All (SS4A) grants.

Funds for the fiscal year (FY) 2026 SS4A grant program are to be awarded on a competitive basis to support planning, infrastructural, behavioral, and operational initiatives to prevent death and serious injury on roads and streets involving all roadway users, including pedestrians; bicyclists; public transportation, personal conveyance, and micromobility users; motorists; and commercial vehicle operators.

The SS4A Grant Program includes: 1) Planning and Demonstration Grants; and 2) Implementation Grants.

Implementation Grants

Implementation Grants fund projects and strategies identified in an Action Plan that address roadway safety problems. Implementation Grants may also fund supplemental planning and demonstration activities, as well as project-level planning, design, and development activities for projects and strategies identified in an Action Plan (e.g., project-level 21 National Environmental Policy Act (NEPA) compliance, associated environmental review activities, permits and approvals, construction design, etc.). 

• Expected number of awards: 40 to 70

The AHRQ is inviting proposals for research focused on improving diagnostic safety in ambulatory care settings. This funding opportunity aims to understand the incidence and contributing factors of diagnostic errors that occur across various ambulatory care services. Proposals should address the complexities of diagnostic safety to enhance patient care and outcomes.

The NASPGHAN Foundation Abbott Advanced Fellowship in Pediatric Nutrition offers up to $75,000 for one year of advanced training in pediatric nutrition for members of NASPGHAN. This fellowship aims to enhance pediatric nutrition expertise by supporting a well-defined clinical experience and focused research project. Eligible applicants must be MDs or DOs and members in good standing, with a preference for those seeking training at different institutions. This initiative addresses the increasing importance of pediatric nutrition in child health.

The National Institute on Drug Abuse (NIDA) invites applications for longitudinal cohort studies focusing on HIV and substance use. This initiative aims to foster multidisciplinary research addressing HIV-associated co-morbidities and substance use disorders. The program encourages collaboration with a NIDA-funded Coordinating Center to enhance research agendas that align with NIH-HIV priorities, ensuring impactful policy and practice outcomes in the field of HIV/AIDS and substance use.

The Indigo Oak Fund, a Colorado-based private foundation, focuses on empowering women and children through various initiatives. By funding organizations that address issues such as domestic abuse, food insecurity, and gender equity, the Fund aims to improve lives and foster lifelong learning. Their mission emphasizes recognizing individual potential and ensuring equal opportunity for all, making a significant impact in communities across Colorado and the Bay Area.

The Southern NM Down Syndrome Families Scholarship Fund Endowment aims to provide financial support for individuals with Down syndrome pursuing post-secondary education or life skills training at accredited institutions. Managed by the Community Foundation of Southern New Mexico, this scholarship embodies the mission of improving quality of life and fostering educational opportunities for diverse communities. It encourages applicants from various backgrounds, including those with disabilities, to achieve their academic and personal goals.

The NIDA Core "Center of Transformative Science" Grant Program aims to enhance research on substance use, addiction, and HIV by fostering collaboration among NIH-funded researchers. Centers are expected to innovate and extend existing research through shared resources and support for new investigators. This initiative encourages interdisciplinary work and aims to transform the scientific landscape by promoting data sharing and collaborative opportunities. Applications should focus on integrating research within a specific thematic framework to maximize impact.

Who We Are - CAP Foundation

Mission

Our mission is to improve people’s health by:

• Developing tomorrow’s pathology leaders through awards for advanced training, research, and education.
• Mobilizing pathologists to expand health equity in medically underserved communities within the US and globally.

Vision

Our vision is that pathologists are equipped to bridge health disparities and enhance outcomes globally.

CAP Foundation History

For over 50 years, the CAP Foundation has granted millions of dollars to support pathology education, research, training, and travel grants, with the purpose to:

• Enhance the role of the pathologist in the provision of medical care.
• Advance pathology through the education of the medical community.
• Encourage the clinical application of research developments.

Our Core Values

• Advancement: We are committed to pushing the boundaries of pathology and patient care through scholarships, grants, and educational programs.
• Collaboration: Through effective partnerships, we significantly enhance our capacity to fulfill our mission.
• Excellence: We are dedicated to achieving the highest standards in pathology education, research, and community service.
• Service: Service reflects our core mission of improving health equity by providing access to healthcare and pathology expertise, particularly in underserved communities.

Presidential Pathology Scholarship

This scholarship allows the sitting CAP President to personally support educational creativity, expand awareness of pathology, and connect communities through the CAP Foundation’s mission to develop tomorrow’s pathology leaders. This scholarship is established in honor of each sitting CAP President, as a commitment to the CAP Foundation’s efforts to advance the specialty by supporting creative projects that encourage interest in or expand the reach of pathology. Up to two scholarships will be supported each year. Ranging from $500-$1,500 per awardee, to be used toward the selected project(s).

Each year the sitting CAP President will select a focus area to support based on at least one of the CAP Foundation’s Five (5) Pillars. CAP Foundation Five Pillars:

• Global: Expands global pathology access, capacity, training, and equity.
• Future Leaders: Builds pipeline through learning, leadership, mentorship, and awards.
• Ethics, Research, Innovation: Advances ethical practice, discovery, innovation, and diagnostic excellence.
• Advanced Training: Delivers specialized skills through grants, workshops, and roundtables.
• Community Engagement: Increases visibility and connection with patients, partners, and the public.

The Downing-Nix Trust Grant provides funding for organizations engaged in research on muscular dystrophy, maintaining treatment wards in Atlanta hospitals, offering veterinary medicine scholarships, and supporting shelters for small animals. Organizations must qualify as 501(c)(3) charities. Applications are accepted year-round, but submissions by April 15 are required for annual meeting reviews. Priority may be given to hospitals and veterinary schools within Atlanta, GA.

The Gospel Fest Music Arts Scholarship, established by Vicki Hill of WTLZ-FM, aims to support Saginaw County students pursuing degrees in Musical Arts. This initiative is part of a larger effort by the Saginaw Community Foundation to enhance local education through scholarships and grants. The annual Gospel Fest, attracting up to 2,000 attendees, serves as a vibrant community event promoting peace and cultural unity through music, showcasing both local and national talent.

The Avant Garde Award supports innovative research on HIV and substance use disorders, encouraging creative scientists to explore high-risk, high-reward approaches. While applications are not currently being accepted, this initiative by the National Institute on Drug Abuse (NIDA) aims to stimulate collaborations and impactful research. Early-stage investigators are particularly encouraged to consider this opportunity as they develop their proposals for future funding. The program uses the DP1 activity code, fostering transformative advancements in biomedical and behavioral science.

The NINDS Exploratory Clinical Trials for Small Business (R43/R44 Clinical Trial Required) grant supports small businesses in conducting innovative clinical trials relevant to neurological disorders. This funding opportunity encourages investigator-initiated projects evaluating drugs, devices, and therapies aligned with NINDS goals. Applications are accepted only from SBIR Phase II and Fast-Track applicants, with a submission deadline of 5:00 PM local time. Letters of Intent are encouraged 30 days prior to the full proposal deadline.

The PERF: Career Development Grants - CNS Elterman Research Grant, established by the Pediatric Epilepsy Research Foundation in partnership with the Child Neurology Society, supports early-stage investigators in pediatric neurology. Eligible candidates can receive $150,000 over two years to conduct clinical or basic science research. This initiative aims to foster the development of researchers focused on pediatric epilepsy and related conditions, enhancing the field through innovative studies and collaboration.