Best Grants for New Nonprofits in South Dakota

The AOAP Swim Lesson Grant aims to enhance drowning prevention by providing financial support to aquatic facilities for swim lessons and life jackets. With a minimum allocation of $10,000 annually, the program seeks to offer at least 100 free lessons to low-income participants and distribute 500 life jackets each year. It encourages non-profit organizations to apply, ensuring a focus on education and safety in aquatic environments. This grant represents a significant step towards making swimming accessible and safe for all.

Native Forward awards are allocated based on the financial aid information provided by the institution’s Financial Aid Office. Awards can vary, ranging from $100 to $30,000 per academic year.

Native Forward Scholars Fund members of federally and state-recognized Tribes as well as first and second-generation descendants. However, Native Forward Scholars Fund scholarship opportunities have different Tribal eligibility requirements and can be determined by submitting a Tribal Eligibility Certificate.

Jeanette Elmer Scholarship

This opportunity is provided to honor the life and legacy of Jeanette Elmer.

The purpose of the Jeanette Elmer Scholarship program is to provide financial assistance to eligible American Indian and Alaska Native graduate students pursuing degrees full-time at an accredited institution in library science.

This opportunity is a need-based award.

Ann Query Scholarship

Graduating senior who attends public, private, or home school and resides in the Zeeland Public School District area (student does not have to attend Zeeland Public Schools to be eligible)

Unless noted otherwise in the scholarship description and criteria statement, applicants can attend accredited schools of their choice within the United States.

CFNJ scholarships awards vary. On average, awards range from $500 to $2,500. However, the award could be larger based on the number of qualified applicants and the parameters set by donors who have established the funds. 

James L. and Ruby L. Murray Memorial Scholarship

This scholarship will be awarded to a college-bound, graduating senior from one of the following high schools: Trenton High School, Ewing High School, Cherry Hill High School West, or East Orange High School. Applicants must be pursuing a bachelor’s degree in history, social science, or political science at any college/university of their choice within the United States. Students also must have achieved a cumulative 3.0 GPA or better.

The Safety, Security, and Privacy for Open-Source Ecosystems (Safe-OSE) program, launched by the National Science Foundation (NSF), addresses vulnerabilities in open-source products and their development infrastructure. It invites proposals to enhance safety, security, and privacy across various types of open-source ecosystems. The program aims to support initiatives that improve resilience against risks, attacks, and breaches, ensuring that OSEs can effectively manage current and future challenges.

The NIH invites applications to study environmental factors affecting animal research rigor and reproducibility. This initiative encourages core facilities and investigators to enhance scientific understanding through modern equipment that measures various biological and behavioral variables. Proposed research must align with NIH's mission, addressing critical processes impacting multiple organ systems. The goal is to improve the reliability of animal studies by systematically evaluating extrinsic influences in biological contexts.

The Warren Alpert Foundation supports initiatives aimed at enhancing public health through grants exceeding $25,000 for medical research, education, and basic human services. Applications are reviewed quarterly, with deadlines preceding board meetings. The foundation's mission encompasses advancing medical treatments and cures through rigorous research and health education. This commitment empowers various projects that align with their vision of improving community health and fostering innovation in medical practices.

The National Cancer Institute (NCI) invites applications for transformative research in cancer biology and oncology through nanotechnology. This funding opportunity aims to address significant challenges by exploring the interactions of nanomaterials with biological systems. Projects should focus on utilizing nanoparticles and devices for targeted cancer therapies and enhancing diagnostic capabilities. Successful proposals will contribute to the foundational knowledge necessary for future nanotechnology-based interventions in cancer treatment.

The Jason Reynolds / Simon & Schuster Travel Grant supports five black/African American youth and teen services librarians annually. Each grant, ranging from $1500 to $3000, covers expenses for travel, housing, registration, and attendance at the ALA Annual Conference, including the Coretta Scott King Awards Breakfast. This initiative aims to empower underrepresented librarians in their professional development and community engagement.

This grant aims to enhance safety and health in U.S. mining operations through research in automation, robotics, and intelligent systems. It addresses critical issues like emergency communication and self-escape reliability while supporting the development of field-ready solutions. By leveraging advanced technologies, the initiative seeks to improve miner safety and health, reduce hazardous exposures, and foster community engagement. Applicants must be U.S. academic institutions with accredited mining programs, linking project goals to documented health burdens.

The NABG Scholarships support full-time undergraduate and graduate students in Geoscience programs at accredited institutions, with over $300,000 in funding raised through donations and events. Candidates must exhibit academic excellence, aiming to equip them for future careers in the geosciences. This initiative, backed by the National Association of Black Geoscientists, fosters diversity and prepares the next generation of professionals in the field.

Self-Defense Grants for MMIR Day

Facilitators, educators, organizers — May 5th is the Day of Awareness for Missing & Murdered Indigenous Women, Girls and Relatives. In honor of that day, we are offering mini grants to host a self-defense workshop for Indigenous girls and gender-expansive youth.

Why self-defense?

• Native women are murdered at 10x the national rate
• 84% experience violence in their lifetime
• Over 5,700 Native girls go missing each year

We also name the invisible crisis:

• Indigenous people from Mexico & Central America (Maya, Nahua, Zapotec, Mixtec, Lenca, and others) living in the U.S. face detention, deportation, and disappearances that are rarely counted in MMIR data.
• When a Tzotzil 18 year old like Royer Perez Jimenez dies in ICE custody, the silence is deafening.

Self-defense must include all Indigenous relatives.

XCNC has:

• $500 mini grants for stipends, space, supplies, and translation.

What we ask:

• Plan a workshop between May 5–31, 2026, rooted in community care.

The Patient-Centered Outcomes Research Institute (PCORI) is funding Cycle 3 to enhance patient-centered comparative clinical effectiveness research (CER). This initiative targets critical methodological gaps, focusing on improving the use of artificial intelligence, study design, data research networks, and ethical protections. By addressing these areas, PCORI aims to strengthen the quality of evidence in CER, thus promoting better outcomes in healthcare decision-making.

The Patient-Centered Outcomes Research Institute (PCORI) is offering funding up to $750,000 for studies aimed at addressing critical methodological gaps in patient-centered comparative clinical effectiveness research. This initiative focuses on enhancing the quality of evidence in clinical research by prioritizing areas such as artificial intelligence, study design improvements, support for data research networks, and ethical considerations. Successful proposals will contribute to advancing research methodologies and improving patient outcomes.

Better World Scholarship Fund

The scholarship encourages women to acquire a degree in a science, technology, engineering, or math (STEM) field. The donor’s bachelor’s degree is in mathematics, followed 15 years later with a master’s degree in business administration. Her degree in mathematics provided opportunities for jobs in software development and application, medical research, technical documentation, organizational education and training, scientific research, and business. Her career was challenging, dynamic, encouraged creativity, never boring, offered schedule flexibility that allowed her to parent her four children, provided career choice independence, and was lucrative. Go STEM Girls!

Award Amount:

• Minimum $1,000

The Patient-Centered Outcomes Research Institute (PCORI) Funding Announcement aims to enhance methods for conducting patient-centered comparative clinical effectiveness research. This initiative seeks to address critical methodological gaps, focusing on improving the use of artificial intelligence in clinical research, study design, data research networks, and ethical protections in patient-centered CER. With a budget of up to $750,000, successful proposals will contribute to the quality and strength of evidence generated in CER studies.

Dr. Jill Biden Scholarship - Biden Breast Health Initiative

Essay:

• Why have you chosen a career in health care or education, and why do you feel it is important to encourage others to adopt a healthy lifestyle?

Awards:

• One time award of $2,500; one award per county. 

Community Foundation of the Holland/Zeeland Area

Our Mission

The Community Foundation of the Holland/Zeeland Area seeks to ensure that our community thrives today, tomorrow, and forever by building our Community’s Endowment to support high impact charitable projects, helping donors achieve their charitable goals, and leading and partnering in community-level initiatives.

Scholarships

CFHZ awards over $1 million in scholarships each year for students to attend schools of higher education throughout the nation. Our scholarships are possible thanks to the generosity of donors who invest in our community’s future by furthering the education of others.

All Holland/Zeeland area individuals interested in post-secondary education are encouraged to apply for CFHZ scholarships.

The Foundation proudly administers over 100 scholarships, each with unique eligibility criteria that must be met before a candidate can be considered.

Peter and Huberdina Weller Scholarship

• Graduating senior, graduating early college student, or current college student from a high school within the greater Community Foundation service area
• Enrolling/enrolled at an accredited post-secondary school within the United States
• Financial need (must submit the page of the FAFSA Submission Summary showing the Student Aid Index amount)
• GPA of 3.0 or greater
• Intention to pursue educational opportunities and a career in horticulture or the biological sciences with an emphasis on botany
• All other qualifications being equal, tie-breaking consideration will be given to students of color
• Previous recipients of the award are encouraged to reapply.

The AOAP Life Jacket Grant supports aquatic facilities in drowning prevention by offering funds for swim lessons and life jackets. Administered by the Association of Aquatic Professionals, the program aims to provide at least 100 free lessons and distribute 500 life jackets annually. This initiative promotes safety education and awareness of life jacket usage, ensuring that underserved communities have access to vital water safety resources. Applications are open to AOAP members meeting eligibility criteria.

Communities Foundation of Oklahoma

The Communities Foundation of Oklahoma stems from the vision of Tom McCasland Jr., and Gene Rainbolt. Two decades ago, these gentlemen formed a shared vision to create a single philanthropic organization to serve the charitable needs to rural communities across the great state of Oklahoma. Today, CFO has grown to assist hundreds of efforts in more than 45 counties.

Scholarship Opportunities

CFO offers over 100 diverse scholarship opportunities, empowering students across the state to pursue their educational goals. Each scholarship is tailored to meet unique needs, making higher education more accessible for all.

Ashley Parks Creative Scholarship

Supports continued education in the arts or creative fields for non-traditional students.

Our Mission

KidsGardening creates opportunities for kids to play, learn, and grow through gardening, engaging their natural curiosity and wonder.

We want every child to experience the unique transformation that occurs when they spend time caring for a garden, be it outside, in a classroom, or in a cup on the kitchen windowsill. Since 1982, KidsGardening has served as a premier support provider for youth garden programs nationwide.

We support educators and families with grant funding, original educational resources, inspiration, and community to get more kids learning through the garden.

Growing the Future Intergenerational Garden Grant

In celebration of Miracle-Gro’s 75th anniversary, Miracle-Gro and KidsGardening are partnering to fund 75 intergenerational youth garden grants in 2026.

Intergenerational gardens provide opportunities for older gardeners to pass along traditions, knowledge, and skills to the next generation or share the experience of developing skills if new to gardening. In turn, young people bring their curiosity, wonder, and contagious enthusiasm for learning and life, exciting everyone involved in the growing process.

The 2026 Growing the Future Intergenerational Garden Grant is designed to support gardens that intentionally bring children and older adults together through shared gardening experiences.

Funding Priorities

The selection of winners is prioritized based on demonstrated need and program impact. KidsGardening considers a variety of factors when determining needs, including:

• Socioeconomic & Sociodemographic Factors: How does the program exist within or engage a community that has been systematically denied resources, whether physical assets and money or representative leadership and community services? Organizations affected by multiple socioeconomic and sociodemographic factors are given priority.

• Program Funding and Support: Does an organization have access to consistent, substantial monetary support or prior grant funding? Or are pre-existing resources (financial or otherwise) limited? Organizations experiencing the latter are given priority.

• Impact: Will grant funding dramatically expand learning opportunities for program participants? Does the intended impact reflect the needs of the community? Organizations working with more than 50 youth will be given priority.

Award Packages

Grantees will receive:

• A $500 cash award check
• A $250 coupon to purchase essential gardening supplies from ScottsMiracleGro.com

The Chan Zuckerberg Initiative is calling for transformative research proposals through the Advancing Technologies for Spatiotemporal Omics in Live Tissue program. This initiative seeks to combine innovative engineering with biological research to explore the complex molecular dynamics of health and disease. By fostering collaboration among scientists and AI experts, this funding aims to unlock new high-precision interventions, significantly advancing our understanding and management of health issues.

The MPS Physics Research Programs, funded by the National Science Foundation (NSF), support transformative research in various fields of physics. This includes experimental and theoretical work in atomic and molecular physics, particle physics, gravitational physics, and more. The NSF aims to promote ambitious projects without the need for immediate commercialization, focusing instead on foundational advancements that push the boundaries of our understanding of the universe.

Steven Thayer Hopi Scholarship

This scholarship was established by the family of Steven Thayer to provide scholarship funding for young Hopi artists to develop their talents and artistic skill.

The Maximizing Investigators' Research Award (MIRA) program, established by NIGMS, aims to enhance research funding efficiency by providing stable financial support to investigators. This allows for greater scientific flexibility and encourages innovative studies. MIRA is pivotal for distributing funding among promising researchers, fostering groundbreaking research. The program invites applications from eligible NIGMS-funded and NIH-defined New Investigators, as well as current MIRA grantees seeking renewal, ensuring a broad and inclusive approach to advancing science.

The Orphan Kitten Club’s Mightycat Grant Program offers financial assistance to individuals and organizations dedicated to saving neonatal kittens. Funding supports essential needs such as medical care, supplies, and innovative programs aimed at improving survival rates. Eligible applicants include 501(c)(3) organizations and independent rescuers with a proven track record in kitten care. The program's mission is to enhance rescue efforts and provide vulnerable kittens the opportunity to thrive and find loving homes.

The Bonnie Plants 3rd Grade Cabbage Grant Program inspires young students to cultivate a love for gardening by providing free oversized cabbage plants to 3rd grade classrooms across the continental U.S. Initiated in 1996, the program encourages hands-on learning about where food comes from. Each year, students compete for a $1,000 prize awarded to the best cabbage grown, fostering excitement and education about agriculture. This initiative not only promotes environmental awareness but also engages students in practical science.