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Best Grants for Small Nonprofits in South Dakota

Find the perfect Grants for Small Nonprofits in South Dakota on Instrumentl. 9,000+ Grants for Small Nonprofits in South Dakota in the United States.

9,000+

Available grants

$2.62B

Total funding

$5K

Median grant

9,000+ grants
$2.62B total
$5K median

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9,025 Results based on applied filters

Musicians Foundation Grant

MUSICIANS FOUNDATION INC
Private
United States
Unspecified amount
The Musicians Foundation Grant provides financial assistance to professional musicians in need, covering medical and dental bills, living expenses, and other essential costs during emergencies. Applicants must demonstrate at least five years of professional experience and apply for reasons beyond loss of work. The grants are issued as vendorized checks to ensure immediate support. This program is not designed for COVID-19 assistance or general income support, focusing instead on urgent hardship cases.
Health Care Access & Delivery Health Disparities & Social Determinants of Health Crisis Intervention

Multiple Sclerosis Foundation: Homecare Assistance Grant

Multiple Sclerosis Foundation Inc
Private
United States
Unspecified amount

Homecare Assistance Grant

MS Focus understands the daily needs and challenges that must be met by both those with MS and their caregivers. In order to meet these needs in the most timely and efficient way possible, our Homecare Assistance Grant connects you to the best available local services. Should resources within your community not be available, direct support may be provided on a temporary basis.

Available Services include:

  • Home Care - Personal hygiene services, light housekeeping, grocery shopping, meal preparation, and transportation to and from appointments are all services that can be provided for a limited time.
  • Therapy Visits - Based upon individual need, an appointment with an occupational, physical, or speech therapist can be arranged. Through education and training, these therapists can help to foster independence, self-esteem, and better quality of life for the person living with MS.
  • Respite Care - Respite allows primary caregivers the opportunity to tend to themselves, or other family business, with the assurance that their loved one is being cared for by a properly trained individual. This service is provided on a short-term basis for a scheduled period of time. 
  • Coming Home - Returning home from a stay at the hospital can be a difficult time of transition. We offer a four-hour visit from an aide who will meet the patient at the hospital, provide transportation home, and then get the patient settled comfortably at home.
Health Care Access & Delivery Physical Therapy Caregiver Support / Respite Care +1 more

Resident Research Preceptorship

Rheumatology Research Foundation
Private
United States
US $15,000
The Resident Research Preceptorship, funded by the Rheumatology Research Foundation, offers a $15,000 award for a three-month, full-time research experience. This initiative aims to inspire medical residents to explore careers in rheumatology research, enhancing the future workforce. By fostering mentorship and hands-on learning, the program supports the development of skilled rheumatology professionals, ultimately improving patient care for those with rheumatic diseases.
Musculoskeletal Diseases Arthritis Medical Education & Professional Training

Rheumatology Future Physician Scientist Award

Rheumatology Research Foundation
Private
United States
Up to US $60,000
The Rheumatology Future Physician Scientist Award aims to enhance the research training of promising students pursuing MD or DO degrees, including those in combined programs. This award supports emerging physician-scientists, promoting their investigative careers in rheumatology. Grants of up to $30,000 per year are available for research projects aligned with the Rheumatology Research Foundation's mission, which focuses on improving patient health outcomes in rheumatic diseases.
Musculoskeletal Diseases Arthritis Medical Education & Professional Training

Sundance Collab's Cultural Impact Residency

Sundance Institute
Private
United States
Unspecified amount
The Sundance Collab's Cultural Impact Residency, honoring Michael Latt, is a six-month online program supporting early-career, underrepresented storytellers focused on social impact. Running from March to August 2026, it offers mentorship, feedback sessions, and resources to eight selected fellows in screenwriting, directing, and documentary filmmaking. This opportunity is designed for works-in-progress, fostering a supportive creative community to inspire and develop impactful narratives.
Film Artist Residencies Writing & Literature +1 more

Health Professional Online Education Grant

Rheumatology Research Foundation
Private
United States
US $1,999
The Health Professional Online Education Grant, offered by the Rheumatology Research Foundation, aims to enhance the skills of non-physician rheumatology professionals. By covering registration costs for the Advanced Rheumatology Course, this grant addresses the growing need for knowledgeable healthcare providers in rheumatology, ensuring better patient care for those with rheumatic diseases. This initiative supports the Foundation's mission to cultivate a robust workforce and improve health outcomes for patients.
Musculoskeletal Diseases Arthritis Medical Education & Professional Training

Mentored Nurse Practitioner/Physician Assistant Award for Workforce Expansion

Rheumatology Research Foundation
Private
United States
US $25,000
The Mentored Nurse Practitioner/Physician Assistant Award for Workforce Expansion, funded by the Rheumatology Research Foundation, aims to increase the number of rheumatology healthcare providers across the U.S. This initiative addresses the growing demand for specialists, particularly in underserved areas. With an award amount of $25,000 for one year, it equips new NP/PAs with essential skills and knowledge needed for successful integration into rheumatology practices, enhancing patient access to quality care.
Musculoskeletal Diseases Arthritis Medical Education & Professional Training

Clinician Scholar Educator Award

Rheumatology Research Foundation
Private
United States
US $210,000
The Clinician Scholar Educator Award, funded by the Rheumatology Research Foundation, aims to enhance education in musculoskeletal and rheumatic diseases for future healthcare professionals. With an award amount of $210,000 over three years, this program supports rheumatology professionals dedicated to education and training, ensuring a well-prepared workforce to meet the growing needs of patients with rheumatic diseases.
Musculoskeletal Diseases Arthritis Medical Education & Professional Training

Fellowship Training Award

Rheumatology Research Foundation
Private
United States
Up to US $150,000
The Fellowship Training Award by the Rheumatology Research Foundation aims to enhance the rheumatology workforce by supporting fellows in ACGME-accredited training programs. The award provides $50,000 per year for up to three years, ensuring a steady supply of qualified rheumatology providers and educators. Special emphasis is placed on supporting underrepresented populations in medicine. This initiative is crucial for improving patient care in rheumatic diseases across diverse communities.
Musculoskeletal Diseases Arthritis Medical Education & Professional Training

Fellowship Training Award for Workforce Expansion

Rheumatology Research Foundation
Private
United States
Up to US $150,000
The Fellowship Training Award for Workforce Expansion, offered by the Rheumatology Research Foundation, aims to improve access to rheumatology care by supporting the training of fellows at institutions facing funding constraints. This $50,000 per year award, available for up to three years, seeks to ensure a sufficient supply of rheumatology providers, particularly in underserved areas, thereby enhancing the quality of care for patients with rheumatic diseases.
Musculoskeletal Diseases Arthritis Medical Education & Professional Training

LEGO Foundation Fellowship

Social Science Research Council
Private
Countries
US $300,000

The LEGO Foundation Fellowship

Advancing the science and practice of supporting children to thrive

The LEGO Foundation Fellowship is a global initiative supporting researchers working to deepen our understanding of how children thrive. Spanning disciplines from education and psychology to public health, data science, and humanitarian studies, the fellowship brings together early- and mid-career scholars whose work has the potential to generate evidence that matters for children’s lives.

Fellows receive three years of flexible support to pursue rigorous, practically relevant research, and join a cohort of peers working across the fellowship’s themes. In addition to funding research, the program fosters a community of scholars engaged in meaningful exchange with one another and with research, policy, and practice audiences.

The LEGO Foundation Fellowship is developed in partnership with the LEGO Foundation, and administered by SSRC as part of its commitment to supporting scholars whose work bridges research and real-world impact.

Research themes

The LEGO Foundation Fellowship welcomes research proposals that advance understanding of children’s thriving through one of the following three themes: the youngest children in crisis and conflict settings; inclusion and wellbeing of neurodivergent children; and children’s learning and development in an AI-enabled world. Applicants may explore the role of play where it is relevant to the research question. The consideration of play is optional and not a condition of eligibility.

Child Welfare Services Special Needs Education Diversity, Equity & Inclusion +3 more

Providers Clinical Support System – Universities

Substance Abuse and Mental Health Services Adminis
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Providers Clinical Support System – Universities program aims to equip graduate-level health professional students with the necessary skills to understand, identify, intervene, and treat patients with substance use disorders. By focusing on practical training and comprehensive education, this initiative prepares future practitioners to effectively address the challenges associated with substance misuse, ensuring they are well-prepared upon obtaining their licenses.
Education - Higher Education Workforce Preparation & Job Readiness Addiction & Substance Use Disorders +1 more

ASSP Foundation Career Development Grant

American Society of Safety Professionals (ASSP) Foundation
Association/Society
United States
US $500 - US $1,000
The ASSP Foundation Career Development Grant supports individuals in the environmental health and safety field by providing financial assistance for certification and professional development activities. Since its inception in 1990, the foundation has awarded over $6 million in grants and scholarships, aiming to enhance the skills and careers of safety professionals. Preference is given to applicants who have not previously received a grant, promoting a sustainable talent pipeline within the industry.
Environmental Health Workforce Preparation & Job Readiness Occupational Health & Safety

Pediatric Rheumatology Fellow Research Award

Rheumatology Research Foundation
Private
United States
Up to US $2,500
The Pediatric Rheumatology Fellow Research Award, offered by the Rheumatology Research Foundation, recognizes exemplary scientific abstracts from pediatric rheumatology fellows at ACR Convergence. With a $1,500 award and an additional $1,000 for travel expenses, this initiative aims to promote innovative research and enhance educational opportunities for future rheumatologists. The program underscores the importance of developing a skilled workforce to improve access to specialized care for patients with rheumatic diseases.
Musculoskeletal Diseases Arthritis Children’s Health & Pediatrics

Career Development Bridge Funding Award: R Bridge

Rheumatology Research Foundation
Private
United States
US $200,000
The Career Development Bridge Funding Award from the Rheumatology Research Foundation aims to support early and mid-career researchers facing funding challenges. This program provides $200,000 over two years to help investigators refine their NIH or equivalent grant applications while pursuing innovative research in rheumatic diseases. By fostering the next generation of rheumatologists, the foundation seeks to enhance patient care and advance treatment options for those affected by these conditions.
Musculoskeletal Diseases Arthritis Medical Education & Professional Training

Veterans Food Assistance Program

Disabled Veterans National Foundation
Private
United States
Unspecified amount

Disabled Veterans National Foundation

The Disabled Veterans National Foundation (DVNF) was established in 2007 to support veterans facing challenges that traditional systems could not fully address. From its earliest days, DVNF has been focused on closing critical gaps in care and providing resources that help veterans rebuild their lives with dignity and stability.

Guided by this commitment, DVNF developed its Health & Comfort programs, offering emergency financial assistance, housing transition support, food assistance, comfort kits, and wellness initiatives. These programs are designed to meet veterans where they are and to provide practical solutions that restore hope and stability. Today, DVNF continues to grow as a trusted national nonprofit. Every day, our team works with a clear purpose: to change lives for the men and women who have served our country.

Veterans Food Assistance Program

It is our goal to ensure that no veteran goes hungry by providing essential food assistance and household support, fostering stability and well-being in the lives of our veterans and their families.

The Veterans Food Assistance Program (VFAP) is designed to provide a one-time grant of essential food and household support to veterans and their families, ensuring no veteran goes hungry. With the rising cost of living, especially food prices due to inflation, this program offers a much-needed lifeline to those who have served our country. Once approved, the DVNF program team will handle the shopping for you.

The Veterans Food Assistance Program provides a one-time grant per household to support different family sizes, given the rising cost of food:

  • Married Veterans Grant Allowance
    • Married - No Children up to $250
    • Married - 1 Child up to $300
    • Married - 2 Children up to $450
    • Married - 3+ Children up to $500
  • Single Veterans Grant Allowance
    • Single - No Children up to $200
    • Single - 1 Child up to $300
    • Single - 2 Children up to $350
    • Single - 3+ Children up to $450
Military & Veterans Services Food Access & Hunger Food Security

Alpha Delta Kappa Xi Education Scholarship

Community Foundation of Northern Illinois
Private
United States
Unspecified amount
The Alpha Delta Kappa Xi Education Scholarship supports graduate students pursuing careers in education. This scholarship aims to recognize and foster fellowship among educators, promoting educational excellence and altruism. By providing financial assistance, it encourages aspiring educators to achieve their goals and contribute to the field of education. Eligible applicants can complete a single online application to match with multiple scholarship opportunities, streamlining the application process.
Education Academic Scholarship Programs Social Justice / Human Rights +3 more

Limited Competition: Tribal Institutional Review Board Establishment and Enhancement (TIRBEE)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
United States
Unspecified amount
The TIRBEE funding opportunity supports federally-recognized Tribes and Tribal Entities in establishing or enhancing Institutional Review Boards. This initiative aims to strengthen the capacity for biomedical research involving human participants within these communities by improving review and oversight capabilities. Eligible organizations are invited to apply, with applications subject to NIH's standard peer-review process to ensure only the most meritorious proposals are considered.
Epidemiology & Public Health Native American Services Health Disparities & Social Determinants of Health +1 more

Periodic Paralysis Grant

Patient Advocate Foundation
Private
U.S. Territories, United States
US $750 - US $1,500
The Periodic Paralysis Grant, offered by the Patient Advocate Foundation, assists individuals diagnosed with periodic paralysis in managing out-of-pocket healthcare costs. Eligible applicants must be in treatment or planning to begin treatment for this rare muscle disease. The fund covers various expenses, including medication copays and insurance premiums, ensuring that patients can afford essential care. With a mission to empower and support patients, this grant plays a crucial role in navigating healthcare challenges.
Rare Diseases Health Care Access & Delivery Health Disparities & Social Determinants of Health +1 more

Native American/Native Hawaiian Museum Services (2027)

Institute of Museum and Library Services (IMLS)
Federal Government
United States
US $5,000 - US $250,000
The Native American/Native Hawaiian Museum Services (NANH) program, funded by the Institute of Museum and Library Services (IMLS), aims to support Native American Tribes, Alaska Native Villages, and organizations serving Native Hawaiians. It focuses on preserving heritage and culture through educational services, workforce development, capacity building, community engagement, and effective collections stewardship. This initiative is crucial for sustaining the rich cultural heritage of Native communities.
Community Culture & Heritage Native American Services Museums & Cultural Institutions +1 more

Paroxysmal Nocturnal Hemoglobinuria (PNH) Grant

Patient Advocate Foundation
Private
U.S. Territories, United States
US $6,900 - US $9,500

About Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Who we are and our impact

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Paroxysmal Nocturnal Hemoglobinuria (PNH)

Help with healthcare costs for Paroxysmal Nocturnal Hemoglobinuria (PNH)

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

About the disease

Paroxysmal Nocturnal Hemoglobinuria (PNH), also known as Marchiafava– Micheli syndrome, is a rare disease that is characterized by impaired bone marrow function and destruction of red blood cells. PNH is a rare disease that affects the circulatory system.

Rare Diseases Health Care Access & Delivery Health Disparities & Social Determinants of Health +1 more

Shawnee Fine Arts Club Scholarship

Communities Foundation of Oklahoma
Private
United States
Unspecified amount

Shawnee Fine Arts Club Scholarship

Provides a scholarship to graduating seniors of Shawnee High School, Liberty Academy, or home-schooled residents of Shawnee, Oklahoma with a minimum cumulative GPA of 2.7. Student must be accepted into the university of their choice, majoring in music, visual arts, dance, or drama.

Education - Higher Education Performing Arts Dance +2 more

Mantle Cell Lymphoma Fund

Healthwell Foundation
Private
United States
Up to US $8,500
The Mantle Cell Lymphoma Fund, managed by the HealthWell Foundation, provides financial assistance to underinsured patients diagnosed with Mantle Cell Lymphoma. The fund covers prescription drug copays and Medicare Part B premiums, with a maximum award of $8,500. Eligible patients must have insurance that covers their medication and meet specific income guidelines. The foundation aims to reduce financial barriers to essential treatments, ensuring that patients receive necessary care without undue financial strain.
Health Care Access & Delivery Lymphoma Cancer / Oncology

Hutsell, Alan Scholarship Fund

Noble County Community Foundation
Private
United States
US $500

Hutsell, Alan Scholarship Fund

For a high school senior from Central Noble, East Noble, Wawasee, West Noble or homeschool (homeschooled student must live in Noble County) who will be pursuing advanced education in emergency services involving fire, police, criminal justice and/or EMS.

Awards Per Year:

  • 1 scholarship

Applicant High School:

  • Central Noble, East Noble, Homeschooled, Wawasee, West Noble

Colleges:

  • Any accredited college or university

Areas of Study:

  • Criminal Justice, Emergency Medical Services, Emergency Services, Emergency services involving fire, police, criminal justice and/or EMS.

Education - Higher Education Emergency Medical Care & Services Criminal Justice System Reform +1 more

Hyperoxaluria Fund

Healthwell Foundation
Private
United States
Up to US $8,000
The Hyperoxaluria Fund, managed by the HealthWell Foundation, aims to alleviate financial burdens for underinsured patients suffering from hyperoxaluria, a condition characterized by excessive oxalate in urine. This fund assists with prescription drug copays and insurance premiums, providing vital support for treatments. In 2024 alone, HealthWell allocated over $1.2 billion in grants, ensuring access to essential medications for those in need. The organization is committed to improving healthcare access and reducing disparities for affected individuals.
Health Care Access & Delivery Kidney Diseases Genetic Conditions & Birth Defects

Erin Marie Masling Memorial Scholarship

Rochester Area Community Foundation
Private
United States
More than US $500

Erin Marie Masling Memorial Scholarship

This scholarship encourages students who have the potential and desire to pursue a post-secondary education despite the effects of an ongoing medical condition or illness.

Number and Size of Awards

Number of recipients and award amounts vary; minimum award $500. Award paid in one lump sum in the Fall and divided equally between the Fall and Spring semesters.

Allowed Use of Award

Awards may be used for tuition, fees, books, and other expenses associated with higher education.

Education - Higher Education Cystic Fibrosis Chronic Illnesses

Metabolic Dysfunction-Associated Steatohepatitis Fund

Healthwell Foundation
Private
United States
Up to US $8,000
The Metabolic Dysfunction-Associated Steatohepatitis Fund, established by the HealthWell Foundation, aims to alleviate financial burdens for underinsured patients facing chronic illnesses. It provides critical support for expenses related to prescription copays, insurance premiums, and transportation for treatment. With a maximum award of $8,000, the fund ensures that individuals can access necessary healthcare services without financial strain. This initiative emphasizes the commitment to improving health outcomes for those affected by metabolic dysfunction-associated steatohepatitis.
Health Care Access & Delivery Liver Disease Cystic Fibrosis +1 more

Grants for Small Nonprofits in South Dakota Highlights

Looking for grants for small nonprofits in South Dakota?


Read more about each grant below or start your 14-day free trial to see all grants for small nonprofits in South Dakota recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Grants for Small Nonprofits in South Dakota

Grant Availability

How common are grants in this category?

Uncommon — grants in this category are less prevalent than in others.

100+ Grants for Small Nonprofits in South Dakota grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

30 Grants for Small Nonprofits in South Dakota over $25K in average grant size

23 Grants for Small Nonprofits in South Dakota over $50K in average grant size

23 Grants for Small Nonprofits in South Dakota supporting general operating expenses

91 Grants for Small Nonprofits in South Dakota supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

600+ Grants on Instrumentl focused on Food Access & Hunger

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for grants for Small Nonprofits in South Dakota?

Most grants are due in the first quarter.

Q1
34.7%
Q2
24.6%
Q3
19.8%
Q4
21.0%

Typical Funding Amounts

What's the typical grant amount funded for Grants for Small Nonprofits in South Dakota?

Grants are most commonly $10,000.

$250 $250 Min.
$10,000 $10 K Median
$89,650 $89.7 K Average
$1,250,000 $1.3 M Max.

Average Grant Size

What's the typical amount funded for South Dakota?

Grants are most commonly $110,621.

$110,621

Total Number of Grants

What's the total number of grants in Grants for Small Nonprofits in South Dakota year over year?

In 2024, funders in South Dakota awarded a total of 6,460 grants.

2022 6,268

2023 6,140

2024 6,460

Top Grant Focus Areas

Among all the Grants for Small Nonprofits in South Dakota given out in South Dakota, the most popular focus areas that receive funding are Education, Human Services, and Philanthropy, Voluntarism & Grantmaking Foundations.

1. Education

2. Human Services

3. Philanthropy, Voluntarism & Grantmaking Foundations

Funding Over Time

How is funding for Grants for Small Nonprofits in South Dakota changing over time?

Funding has increased by 17.48%.

2022 $638,830,994

2023 $606,495,212
-5.06%

2024 $712,509,384
17.48%

South Dakota Counties That Receive the Most Funding

How does grant funding vary by county?

Minnehaha County, Lake County, and Pennington County receive the most funding.

County Total Grant Funding in 2024
Minnehaha County $176,653,145
Lake County $117,647,066
Pennington County $90,630,616
Brookings County $75,457,854
Todd County $56,559,538