Best Operating Grants for Nonprofits in South Dakota

The Innovations for Healthy Living program invites eligible U.S. small businesses to apply for SBIR grants aimed at improving minority health and eliminating health disparities. The initiative encourages innovative proposals for effective, affordable, and culturally acceptable solutions. Key deadlines for applications span from June 2024 to December 2026, with optional Letters of Intent recommended 30 days prior to submission. This funding opportunity supports projects that address health challenges faced by underserved populations.

The Technologies for Improving Minority Health and Eliminating Health Disparities (R41/R42) program invites small business concerns to develop innovative technologies aimed at enhancing minority health and addressing health disparities. This initiative emphasizes the creation of effective, affordable, and culturally acceptable solutions for NIH-defined populations. Key deadlines for applications span from June 2024 to December 2026, with optional Letters of Intent encouraged 30 days prior to submission.

The T.E.A.L. Research Grant supports innovative ovarian cancer research initiatives aligned with the mission of the Tell Every Amazing Lady About Ovarian Cancer Foundation. Designed for researchers affiliated with 501(c)3 not-for-profit institutions in the U.S., the grant aims to enhance women's health awareness and education regarding ovarian cancer. While the application period for 2025 is currently closed, interested parties should anticipate further updates in spring 2026.

The Simply Organic Giving Fund Grant aims to combat food insecurity in the U.S. and Canada by providing access to nutrient-dense organic food for those in need. Since its inception, the fund has supported various initiatives, including training centers for organic agriculture and community food projects. With a focus on sustainable practices, the grant program seeks to empower communities and improve food access for vulnerable populations, ensuring that healthy, organic options are available to all.

Ethan J. Hazelwood Heart of Gold Memorial Scholarship

The Ethan J. Hazelwood Heart of Gold Memorial Scholarship was established in 2025 by family and friends of Ethan as a lasting tribute to his life and giving spirit.

Those who knew Ethan remember him as a kind, creative, and giving person. He was always helping others and once gave the boots on his feet to a fellow student who had none.

Open to individuals in Whitley and Noble County, the scholarship is for high school seniors as well as non-traditional students, who wish to pursue additional education in the field of agriculture or diesel mechanics.

The PEO, Chapter BE Scholarship, offered by the Erie County Community Foundation, supports female graduates of Erie County high schools pursuing undergraduate or graduate degrees. Since 1995, the foundation has focused on enhancing community needs and leadership, aiming for a lasting impact in Erie County, Ohio. This renewable scholarship is awarded at the discretion of the Scholarship Advisory Committee, ensuring continued support for students dedicated to their academic pursuits.

The Sandusky Bay Kiwanis Community Services Scholarship supports graduating seniors from several high schools in Erie County, Ohio, including Huron, Margaretta, Perkins, Sandusky, and St. Mary’s Central Catholic. To qualify, applicants must have a minimum GPA of 2.8 and demonstrate a commitment to community service and financial need. This scholarship aims to empower students to contribute positively to their communities while furthering their education.

Native Forward awards are allocated based on the financial aid information provided by the institution’s Financial Aid Office. Awards can vary, ranging from $100 to $30,000 per academic year.

Native Forward Scholars Fund members of federally and state-recognized Tribes as well as first and second-generation descendants. However, Native Forward Scholars Fund scholarship opportunities have different Tribal eligibility requirements and can be determined by submitting a Tribal Eligibility Certificate.

Grace Wall Barreda Memorial Scholarship

This opportunity is provided to honor the life and legacy of Grace Wall Barreda.

The purpose of the Grace Wall Barreda Scholarship program is to provide financial assistance to eligible American Indian and Alaska Native graduate students pursuing degrees full-time at an accredited institution in Public Health or Environmental Science/Studies.

This opportunity is a need-based award.

Arnold Ventures

Arnold Ventures (AV) is a philanthropy dedicated to improving the lives of Americans through evidence-based policy solutions that maximize opportunity and minimize injustice. We focus on improving systems where outcomes are falling short, incentives are misaligned, and the time is right for change. To advance this mission, we invest in rigorous research to strengthen the evidence base on what works to improve outcomes for individuals, families, and communities, and to inform policy and practice at scale.

AV’s Higher Education team seeks to fund rigorous, causal research on programs, policies, and practices that improve student outcomes and deliver stronger returns on investment for students and taxpayers. Our work focuses on strengthening the evidence base on effective student success models and aligning policy and funding incentives to support their adoption and scale.

Causal Research to Improve Outcomes for Part-Time Students

Purpose of the RFP

This RFP seeks to fund rigorous causal research that builds the evidence base on effective programs and policies for part-time students and identifies scalable, cost-effective approaches to improve completion and labor market outcomes. Findings should generate actionable insights to inform institutional practice, system-level decision making, and state policy, with the goal of improving outcomes and maximizing return on investment for students and taxpayers.

Population of Interest

Because enrollment intensity is fluid, proposals do not need to limit eligibility to students who are enrolled part-time at baseline. Instead, studies should focus on interventions that primarily serve or are expected to meaningfully impact students who are more likely to enroll part-time, including:

• Adult learners (age 25+)
• Student parents and caregivers
• Working adults

Interventions may serve mixed-enrollment populations, so long as the proposed study is clearly designed to improve outcomes for these populations.

The AES Infrastructure Grant, offered by the American Epilepsy Society, provides up to $50,000 to support the development of national or international multicenter research programs. This funding is intended for organizational planning sessions, infrastructure development, and pilot projects, facilitating future investments from other organizations. These grants are available annually in the spring, enabling researchers to enhance their collaborative efforts.

The Mystery Donor Vocational Scholarship Fund, managed by the Decatur County Community Foundation, supports local students accepted into vocational schools. This scholarship aims to assist those pursuing hands-on careers through skill development in various institutions or apprenticeship programs. By easing financial burdens, it encourages students to gain practical experience and contribute to their communities, fostering a skilled workforce for the future.

The Child Well-Being Grant Program, established by the Doris Duke Foundation, focuses on promoting the healthy development of children and preventing abuse. With a commitment to addressing systemic inequities, the program supports initiatives that strengthen social service systems and foster partnerships to enhance access to services. It prioritizes funding for projects that encourage community-based interventions and the development of future leaders dedicated to improving child welfare, ensuring all children have the opportunity to thrive in safe and supportive environments.

Patrick Caroselli Scholarship

To provide financial assistance for college to high school seniors in Monroe County whose parents immigrated to the United States and attained citizenship.

Number and Size of Awards

Number of recipients and award amounts vary; award amount may be split between two or more recipients. Award paid in one lump sum in the Fall and divided equally between the Fall and Spring semesters. Average award $5,000; not to exceed the cost of tuition.

Allowed Use of Award

Awards must be used for costs related to enrollment in a higher education program, prioritizing tuition fees.

The E. Wayne Baumgartle Agricultural Memorial Scholarship, managed by the Decatur County Community Foundation, aims to support students from Decatur County, Indiana, pursuing post-secondary education in agriculture. This scholarship seeks to alleviate the financial burden of educational expenses for deserving candidates. Interested students are encouraged to reach out to the local FFA instructor for more information. This initiative reflects the foundation's commitment to fostering community growth through educational opportunities.

Myasthenia Gravis Rare Disease Network (MGNet)

The Myasthenia Gravis Rare Disease Network (MGNet) is a consortium of academic medical centers partnering with the Myasthenia Gravis Foundation of America and Conquer MG as well as collaborators in other research groups and industry. We are working together to enhance therapeutic development for this rare disease.

Diseases Studied

Myasthenia Gravis (MG) and its subtypes:

• Early-onset acetylcholine receptor (AChR) antibody (Ab) positive MG, which primarily affects women
• Late-onset AChR Ab positive MG with a disease bias towards men
• Paraneoplastic thymoma-associated MG
• Muscle specific kinase (MuSK) Ab positive
• AChR/MuSK antibody negative MG

Goals, Mission, & Vision

The goal of MGNet is to advance therapeutic development. To do so we have four specific aims:

• Improve the tools scientists and doctors have for performing clinical trials through rigorous monitoring of patients over time and evaluate better measures of how patients are doing.
• Identify objective measures (biomarkers) to show how the disease is responding to treatment and better predict treatment response or side effects, to improve the design of clinical trials and care of patients in clinical practice.
• Enhance the education of young investigators focusing their careers on rare diseases and specifically MG.
• Improve the awareness of scientists, physicians, and the public regarding the unique needs of patients with MG through training of clinician scientists and engagement of the patient and scientific communities in clinical research and therapeutic development.

Pilot and Feasibility Grants

Objectives

MGNet, a NIH-funded Rare Diseases Clinical Research Consortium (RDCRC) in partnership with the Myasthenia Gravis Foundation of America and Conquer MG, is seeking proposals for highly innovative investigations in early stages of development.

The priorities of the Pilot Grant Program are:

• Identification treatment responsive biomarkers
• Assess clinical measures and improve that enhance clinical trial readiness
• Evaluation of therapeutic interventions for one or more of the five distinct sub-types of MG

Pilot studies must be designed to access the resources of MGNet and focused on clinical and translational research, including fulfilling the definition of clinical and translational research and exclusion of animal studies.

Funding

The MGNet expects to fund up to two grants, each at a level of $75,000 (IDCs will be limited to 10% and included in the $75,000). Projects will be funded for 12 months. Selection among the applications received will be based on the recommendations of a review committee. A grant may be renewed for an additional one year with approval of interim report by the same review process and availability of funds. Demonstration of fulfillment of initial aims and justification for additional funding will be required. The request will be required a minimum of three months prior to the initial funding period completion.

Myasthenia Gravis Rare Disease Network (MGNet)

The Myasthenia Gravis Rare Disease Network (MGNet) is a consortium of academic medical centers partnering with the Myasthenia Gravis Foundation of America and Conquer MG as well as collaborators in other research groups and industry. We are working together to enhance therapeutic development for this rare disease.

Diseases Studied

Myasthenia Gravis (MG) and its subtypes:

• Early-onset acetylcholine receptor (AChR) antibody (Ab) positive MG, which primarily affects women
• Late-onset AChR Ab positive MG with a disease bias towards men
• Paraneoplastic thymoma-associated MG
• Muscle specific kinase (MuSK) Ab positive
• AChR/MuSK antibody negative MG

Goals, Mission, & Vision

The goal of MGNet is to advance therapeutic development. To do so we have four specific aims:

• Improve the tools scientists and doctors have for performing clinical trials through rigorous monitoring of patients over time and evaluate better measures of how patients are doing.
• Identify objective measures (biomarkers) to show how the disease is responding to treatment and better predict treatment response or side effects, to improve the design of clinical trials and care of patients in clinical practice.
• Enhance the education of young investigators focusing their careers on rare diseases and specifically MG.
• Improve the awareness of scientists, physicians, and the public regarding the unique needs of patients with MG through training of clinician scientists and engagement of the patient and scientific communities in clinical research and therapeutic development.

Scholar Awards

Objectives

There is a critical need for investigators prepared to conduct clinical and translational research in myasthenia gravis (MG). The MGNet Scholar Program provides individualized training and mentorship in one of two tracks, Clinical Research or Biomarker Development Research.

Award Description

The MGNet Scholar Program provides mentored research training to prepare Scholars for an independent research career in the field of MG. The MGNet Scholar Program is 1 year in duration and selected Scholars receive up to $100,000 to support salary, research costs and didactics with potential for renewal. The program will provide an additional $3,000 to travel to MGNet sites to learn specific skills and/or to scientific meeting(s) to present the results of their research. If available for renewal, the program requires approval after interim report and is contingent on demonstration of adequate progress on the research and career development plan. Indirect costs are not allowed. Scholars are encouraged to transition to NIH (e.g., K award), departmental, or private foundation support for their research and further career development.Research must constitute at least 50% of each Scholar’s professional effort. Each Scholar must form a 2-3-member advisory committee to include a primary mentor, an additional clinician investigator or collaborator, and a MGNet faculty sponsor. The advisory committee will meet with the Scholar at least quarterly to review progress and each Scholar will develop an individual academic career development plan and renew it with the committee at least every 6 months.

The Donald E. Meier Surgical Humanitarian Award, presented by the American Pediatric Surgical Association, honors a member dedicated to providing surgical care to underserved children without expecting reimbursement. This award recognizes significant humanitarian contributions, whether through local outreach or global missions. Nominations are submitted to the Board, which determines the frequency of the award based on the submissions received. This accolade highlights the commitment of surgeons to humanitarian efforts in the pediatric surgical field.

Jacqueline Hall Minet Travel Award for Cross-Cultural Understanding

To provide financial assistance to a Brighton High School student or a Rochester City School District high school student so that he or she can participate in a travel experience that offers significant opportunities for involvement in a foreign-language culture.

Number and Size of Awards

Number of recipients and award amounts vary; maximum $2,000.

Allowed Use of Award

Awards may be used for expenses associated with travel abroad programs.

The Dalsemer Interstitial Lung Disease Award, funded by the American Lung Association, provides $50,000 per year for two years to support junior investigators researching interstitial lung disease. This award aims to foster independence in early-career scientists while building on the Association's 120-year legacy of improving lung health through innovative research and advocacy efforts, ultimately enhancing the lives of those affected by lung disease.

Dr. Jeffrey Hanson Memorial Scholarship

To support those pursuing careers in medicine, particularly primary care. 

Number and Size of Awards

One award of $2,750; paid in one lump sum in the Fall and divided equally between the Fall and Spring semesters.  

Allowed Use of Award

Awards may be used for tuition, fees, books, and other expenses associated with higher education.

The Craft Archive Fellowship supports archival research on underrepresented craft histories in the U.S., including feminist, queer, Black, Indigenous, and other marginalized communities. It offers a $5,000 stipend for scholars and artists to conduct research in chosen archives, encouraging innovative approaches. Participants will present their findings in a virtual program, and their work will be published in Hyperallergic, broadening accessibility and awareness of vital craft research.

About Legacy Foundation

Legacy Foundation is the community foundation for Lake County, Indiana. We connect people, knowledge, and funding to build an equitable, accessible, and inclusive Lake County, now and for generations to come.

Legacy Foundation is supported by a broad base of individuals, families, and businesses connected by the desire to improve Lake County, Indiana. With a growing portfolio of over 300 funds and approximately $80 million in assets, Legacy Foundation is a trusted source for philanthropic giving in the region.

For over 30 years, Legacy Foundation has been empowering people, providing strategic leadership, and impactful philanthropic support to create an equitable Lake County where all people thrive.

Mission Statement

Transforming Lake County by providing strategic leadership and impactful philanthropic support to ensure equitable opportunity for all communities that we serve.

Vision Statement

Create an equitable Lake County where all people thrive.

Cenifax Scholarship

Use the chart below to see which scholarships are the best fit for you! You must complete the Legacy Universal Application to apply.

Scholarship eligibility requires students to attend an accredited 2 or 4 year public or private institution of higher learning. All scholarships are for full-time students, unless otherwise noted. Renewable awards are for 4 years of undergraduate study and cannot be used for post graduate coursework; all awards are paid directly to the school or may be used for book reimbursement.

The Student Enrichment Grants: Level II Awards, offered by the Music & Entertainment Industry Educators Association (MEIEA), provide up to $500 for non-institutional members to support student activities in music and entertainment. Eligible applicants include faculty in good standing, promoting diverse initiatives. Grants can fund workshops, guest speakers, and community projects, with a focus on enhancing student education and engagement in the industry. Special consideration is given to first-time applicants and impactful projects.

The National Network of STI Clinical Prevention Training Centers (NNPTC) aims to enhance the education and training of clinicians and disease intervention professionals in STI patient care. This initiative focuses on improving the ability of healthcare providers and systems to effectively diagnose, manage, and counsel individuals at risk for STIs, ultimately reducing morbidity and enhancing public health outcomes on both local and national levels.

Samuel “Bo” Terry Scholarship Fund

Fund provides higher education scholarship assistance to needy and deserving students graduating from Roanoke City Public Schools.

Amount

• $500+

Rangeley Educational Fund

Fund provides scholarships to further the education of young men and women pursuing study in technical, vocational, academic, or professional fields.

Amount

$1,000+

Romero Family Scholarship Fund

Fund was established to provide scholarship assistance to further the education of able and deserving young men and women in their post high school education in the fields of either technical, vocational, academic or professional education, with preference given to students from Henry and Franklin Counties and the City of Martinsville.

Amount

• $2,500+