Best Private Grants for Nonprofits in South Dakota

The National Institute of Allergy and Infectious Diseases (NIAID) is advancing research on immune tolerance through its Collaborative Network. This program aims to clarify the mechanisms of immune tolerance and develop interventions for related diseases, including transplant rejection and autoimmune disorders. Key objectives include conducting clinical trials on tolerogenic strategies and refining immune assays. This initiative is supported by regulations under the Public Health Service Act, ensuring a structured approach to improving patient outcomes.

The Continued Achievement Scholarship, offered by the American Academy of Audiology Foundation, provides $2,000 to two promising audiology graduate students in the U.S. It recognizes students for their potential as clinical audiologists based on their resumes and personal statements. This scholarship aims to support full-time graduate students (AuD, PhD) in good standing, fostering their professional development and commitment to the audiology field.

The Translational Transplantation Tolerance Cooperative Study Group, supported by the National Institute of Allergy and Infectious Diseases, aims to advance transplant tolerance strategies that promote long-term graft survival without lifelong immunosuppression. This initiative focuses on developing, optimizing, and evaluating methods to induce immune tolerance in allogeneic transplants through collaborative efforts across multiple centers, utilizing translationally relevant models to ensure effective outcomes.

Youth Service America

Youth Service America believes that youth, communities, and our democracy thrive when we all work together for the common good. YSA is a leading global nonprofit that activates young people, ages 5-25, to find their voice, take action, and acquire powerful civic and 21st Century skills as they solve problems facing their communities. YSA supports its activation campaigns with grants, training and resources, and recognition programs for young people and their adult champions. Youth-led projects use Awareness, Service, Advocacy, and Philanthropy (ASAP) strategies to create social and environmental change.

We Serve To Remember Grants

Projects that Engage 100 Youth Volunteers

YSA’s We Serve to Remember 9/11 Day of Service Grants are for organizations, schools, and youth changemakers ages 5-25 to lead service projects on or around September 11, 2026. Programming efforts should also honor and pay tribute to those who lost their lives on September 11, 2001, their families, and those who rose in service in response to that tragedy. (We suggest starting with eleven reflections about 9/11/01 and related ideas for service or service-learning projects.)

Grantees are required to engage at least 100 youth as volunteers in planning and implementing the service activities.

What are we looking for?

• Projects must be youth-led;
• Projects must include elements to honor and pay tribute to those who lost their lives on 9/11, their families, and those who rose in service in response;
• Projects must take place on or around September 11th National Day of Service and Remembrance (Friday, September 11, 2026) – between Friday, September 4 and Friday, September 18;
• Project organizers must make their best effort to recruit and engage youth volunteers who are not usually asked to serve;

Grantees are also required to provide evidence of volunteer participation and number of hours served. Approved documention includes sign in sheets, copies of pre-and-post-surveys, or reports from school attendance or volunteer management system. These documents must contain a unique identifier for each volunteer, such as the volunteer’s full first and last name, their full first name and last initial, or a volunteer/student ID number.

Reflecting on the spirit of togetherness that brought people together in the days, weeks, and months after September 11th, we are especially looking for ideas that bring together all members of the community.

The Amit Gosalia Scholarship in Private Practice Audiology, funded by the American Academy of Audiology, offers two $1,500 scholarships to full-time audiology students (AuD, PhD) who demonstrate exceptional promise and have completed their first year of studies. Eligible candidates must be enrolled at a U.S. university for the Fall 2025 semester and cannot graduate in Spring/Summer 2025. This initiative aims to support future audiologists pursuing careers in private practice.

Manuel And Fillie Garcia Hispanic Scholarship

The Manuel & Fillie Garcia Hispanic Scholarship was established as a permanent fund of Taos Community Foundation in 2011.

The award is available to graduating seniors in Taos and western Colfax counties with preference to Hispanic students pursuing advancement of higher education. The scholarship is available to those applying to 4 year colleges and universities as well as 2 year vocational/trade schools.

The award amount will be determined at the time of committee review. This award is typically renewable for up to three years if a 2.5 GPA is maintained and all required paperwork is returned in accordance with the Scholarship Agreement.

The Child Well-Being Grant Program, established by the Doris Duke Foundation, focuses on promoting the healthy development of children and preventing abuse. With a commitment to addressing systemic inequities, the program supports initiatives that strengthen social service systems and foster partnerships to enhance access to services. It prioritizes funding for projects that encourage community-based interventions and the development of future leaders dedicated to improving child welfare, ensuring all children have the opportunity to thrive in safe and supportive environments.

The National Institute of Allergy and Infectious Diseases (NIAID) is advancing organ transplantation outcomes through the Clinical Trials in Organ Transplantation in Children and Adults (CTOT-CA) program. This initiative supports multicenter clinical trials and mechanistic studies related to heart, lung, kidney, liver, and intestinal transplants, as well as non-hematopoietic cellular transplantation. By exploring immune mechanisms and innovative therapies, the program aims to enhance the success and efficacy of organ transplantation.

The Bayer Fund: Food & Nutrition Grant supports high-quality programs that combat malnutrition and improve access to nutritious foods, particularly for underserved communities and families with young children. Eligible organizations include 501(c)(3) nonprofits and government units. The fund prioritizes long-term behavioral change towards healthy eating and nutrition, with grants typically not exceeding 25% of an organization's operating budget. International requests start at $25,000, fostering sustainable food security and education initiatives.

The FY26 Bone Marrow Failure Research Program's Resource Development Award aims to create a multiomic atlas from human bone marrow failure samples. This resource will be open-access, providing essential data for researchers and clinicians to enhance their understanding of bone marrow failure diseases. A comprehensive Data Resource Sharing Plan is required to ensure timely availability of the developed resource, fostering collaboration within the scientific community.

The FY26 Breast Cancer Research Program's Transformative Breast Cancer Consortium Award fosters significant collaborations that aim to revolutionize care for individuals affected by breast cancer. This award supports a multidisciplinary consortium of leading scientists, clinicians, and advocates to tackle major challenges in breast cancer research. Proposals must address at least one of the program's overarching challenges and demonstrate a transformative impact that cannot be achieved by individual investigators alone.

The FY26 Parkinson’s Research Program Investigator-Initiated Research Award supports innovative, multidisciplinary research projects aimed at advancing the understanding and treatment of Parkinson’s disease. The award encourages collaboration among multiple principal investigators, requiring preliminary data and allowing clinical trials to enhance research outcomes. This initiative is vital for fostering impactful discoveries within the four specified focus areas of the program, ultimately improving patient care and management.

The DoW Ovarian Cancer Pilot Award fosters innovative research that challenges existing paradigms in ovarian cancer. It aims to propel groundbreaking discoveries and advancements in the field. Notably, the award prioritizes originality over scientific merit alone, ensuring that innovative ideas are at the forefront. The application process includes a blinded pre-application screening to maintain confidentiality and integrity, encouraging fresh perspectives in ovarian cancer research.

The Judith Blumsack Scholarship, offered by the American Academy of Audiology Foundation, awards $500 to a full-time graduate student in audiology who demonstrates exceptional clinical skills and commitment to clinical research and community service. Established in honor of Dr. Judith Blumsack upon her retirement, this scholarship acknowledges her significant contributions to the field and aims to inspire future audiologists to excel in their professional journey.

The Ovarian Cancer Research Program (OCRP) Investigator-Initiated Research Award aims to support impactful research addressing critical needs in ovarian cancer and patient care. It requires a robust research plan with preliminary data and allows for studies across all research phases, excluding clinical trials. A unique Partnering Principal Investigator option encourages collaboration between two PIs to enhance research outcomes beyond individual efforts, promoting innovation in the field of ovarian cancer.

The FY26 Breast Cancer Research Program (BCRP) Breakthrough Award Level 3 supports transformative research aimed at significant advancements in breast cancer treatment. Applicants must address key challenges outlined by the program, ensuring their proposals demonstrate potential for impactful breakthroughs. This funding mechanism, which permits small-scale clinical trials, emphasizes collaboration by requiring research teams to include two breast cancer consumer advocates and allows for a single Principal Investigator or two partnering PIs.

The FY26 Parkinson’s Research Program (PRP) Early Investigator Research Award supports early-career researchers in Parkinson’s disease (PD) research. It offers two funding levels: Level 1 for fellows requiring a Mentor and Level 2 for independent investigators. The PI must show potential in PD research, with Level 1 emphasizing mentorship and Level 2 needing preliminary data. Research must align with one of the four FY26 PRP Focus Areas, excluding clinical trials.

The DoW Ovarian Cancer Clinical Trial Award, funded by the U.S. Army Medical Command, aims to accelerate the implementation of clinical trials that significantly impact ovarian cancer treatment. This award supports diverse trial designs, from early proof-of-concept studies to large-scale efficacy trials, evaluating innovative drugs, biologics, and technologies. By fostering research in this critical area, the program seeks to enhance patient outcomes and advance the understanding of ovarian cancer management.

The Land Trust Bird Conservation Initiative, led by the Cornell Lab of Ornithology, aims to support land trusts in conserving private lands for bird protection. With funding for up to fourteen grants, the initiative encourages capacity building and management projects that enhance bird habitats. Eligible organizations can apply for grants to expand conservation efforts through collaboration and innovative strategies, fostering partnerships that leverage additional funding and community support. This initiative highlights the importance of birds in land stewardship and conservation.

The Gupta Family Foundation Grant aims to empower disadvantaged individuals by providing financial support to organizations that foster self-reliance. Headquartered in Herndon, Virginia, the foundation offers grants ranging from $5,000 to over $250,000, prioritizing smaller organizations with a strong commitment to their missions. Eligibility typically includes US-based IRS 501(c)(3) entities, with operations extending to countries like India and Kenya. The foundation emphasizes mission alignment and effective resource allocation to ensure maximum impact.

The Ovarian Cancer Clinical Trial Academy (OCCTA) supports Early-Career Investigators (ECIs) in clinical trial research aimed at effective ovarian cancer treatments. It provides essential mentoring, networking, and skill development needed for executing clinical trials. The FY26 funding will specifically support translational research and early-phase trials, requiring preliminary data and a commitment of at least 25% effort from the ECI. Mentorship is vital, with a focus on experienced clinical trialists guiding ECIs.

The AAD Shade Structure Grant Program provides funding up to $8,000 for non-profit organizations and public schools to install shade structures, promoting sun safety for children and teenagers. Applicants must demonstrate a commitment to sun safety, including a year-long awareness program, and submit a letter of recommendation from an AAD dermatologist. The program aims to enhance outdoor safety, supported by donations from members and organizations.

The DoW Ovarian Cancer Academy Early-Career Investigator Award supports junior faculty in conducting innovative ovarian cancer research. Established in FY09, this unique virtual academy fosters mentorship, collaboration, and networking among Early-Career Investigators (ECIs) and their mentors. Participants engage in monthly webinars and annual workshops, enhancing their research skills while contributing to impactful studies in ovarian cancer. The program aims to cultivate a new generation of highly productive researchers in this critical field.

The Pediatric Cancer Research Foundation (PCRF) is dedicated to funding innovative research aimed at curing childhood cancer. With a focus on collaborative efforts, PCRF has contributed over $51 million since 1982, significantly improving survival rates for childhood cancers. The Translational Research Grant supports cutting-edge clinical trials and therapeutic approaches, enhancing the journey from laboratory discoveries to patient care. This initiative underscores the urgent need for effective treatments, offering hope for children diagnosed with cancer and their families.

The National Cancer Institute (NCI) invites applications for the validation of biomarkers and assays for cancer detection and treatment. This funding opportunity allows for biphasic or monophasic applications to support both analytical and clinical validation phases. Successful projects will leverage human specimens to develop assays that enhance cancer treatment and prevention, ensuring multidisciplinary collaboration among scientists and clinicians. This initiative aims to improve cancer management through reliable and clinically validated tools.

The DOW Combat Readiness – Medical Research Program's FY26 Translational Research Award supports innovative research aimed at improving trauma care outcomes. This program emphasizes hypothesis-driven studies that can transition promising technologies into practical solutions for enhancing casualty survivability. Applicants must provide preliminary data and utilize validated animal models, with a focus on projects that meet a minimum technology readiness level of 4, ensuring a mature translational research effort.