Best Large Grants for Nonprofit Organizations in Wyoming

About Pfizer Grants

Pfizer supports the global healthcare community’s independent initiatives (e.g., research, quality improvement or education) to improve patient outcomes in areas of unmet medical need that are aligned with Pfizer’s medical and/or scientific strategies.

Pre-clinical Investigation of anti-TFPI-mediated Rebalancing Mechanisms in Non-Hemophilic Bleeding Disorders

There remains a scientific gap in understanding of the role of anti-TFPImediated hemostatic rebalancing in the context of inherited or non-hemophilic bleeding disorders. This competitive grant program encourages competitive submissions focsed on generating preclinical/foundational data exploring the therapeutic potential and mechanisms of TFPI modulation in bleeding disorders other than hemophilia.

Project Types and Area of Interest

Potential applicants are encouraged to identify and address preclinical/basic science data generation for TFPI modulation/rebalancing in their local setting. This may include:

• Rare bleeding disorders which arise from deficiencies in different clotting factors or pathway components but converge on a common functional endpoint which is an impaired thrombin generation (e.g., Factor II, Factor V, Factor VII, Factor X and Factor XI deficiencies, as well as von Willebrand disease).
• Other diseases such as Glanzmann's thrombasthenia (GT) that have a distinct pathophysiological mechanism.
• Other rare bleeding disorders whose mechanisms are not well understood (e.g., Bleeding Disorder of Unknown Cause, BDUC).

The Guy Bradley Award, established in 1988 by the National Fish and Wildlife Foundation (NFWF), honors individuals who have made significant contributions to wildlife law enforcement. Named after the first wildlife officer killed in the line of duty, this award recognizes the vital role of law enforcement agents in wildlife conservation. Eligible candidates include current and retired personnel from state and federal agencies who have demonstrated exemplary dedication to protecting wildlife and advancing enforcement goals.

The St. Baldrick’s Foundation Fellowship Award supports pediatric oncology training through a two-year fellowship, with a potential third year based on need and achievements. This initiative, powered by community fundraising events, aims to advance research for childhood cancer cures. The award provides a salary capped at $97,500 per year, covering salary and benefits for fellows. This fellowship not only fosters professional growth but also contributes significantly to the fight against childhood cancers.

The St. Baldrick’s Foundation Research Grant Award supports innovative research aimed at curing childhood cancers. With funding of $100,000 per year for two years, this grant is designed for hypothesis-driven projects that can be laboratory, clinical, or epidemiological in nature. Established through community-driven fundraising events, the foundation empowers volunteers and donors to make a significant impact in the fight against cancer, ensuring a brighter future for young survivors.

The Minnesota Ovarian Cancer Alliance (MOCA) is offering grants for research focused on the early detection of ovarian cancer. With funding amounts of either $50,000 or $100,000 available, these grants support projects aimed at enhancing prevention strategies. Eligible applicants include U.S.-based researchers outside of Minnesota, and the awards will be distributed in November 2025. This initiative aims to foster innovative approaches to combat ovarian cancer effectively.

Every Battle Creek area resident shall have the resources to access post-secondary education and training.

Your dreams matter — and we want to help you achieve them. Whether you’re a graduating high school senior, an adult returning to school, or a graduate student pursuing advanced education, we’re here to support you by opening doors to opportunity.

Beyond tuition, many funds support total cost of attendance — books, fees, equipment, and in some cases childcare or transportation.

Checks are made payable to the educational institution indicated on the follow-up and mailed directly to the educational institution. Checks are typically mailed in early August.

In God We Trust, Mitchelle T. Savage Memorial Scholarship Fund

The In God We Trust, Mitchelle T. Savage Memorial Scholarship was established to provide educational opportunities beyond high school for Battle Creek area graduates or graduating seniors. Eligible recipients will be graduating seniors from Battle Creek area public and private schools who will be attending a college that is a member of the Council for Christian Colleges and Universities.

 Advancing Markets for Producers Grants

ALB has received a USDA AMP (Advancing Markets for Producers) grant, and we’re excited to invite sheep producers to be part of this opportunity to help grow the US sheep industry. This grant will integrate new technology and sustainable management strategies to boost productivity, open new markets, and strengthen opportunities for the next generation of producers.

Producer Program

The project will provide an opportunity for 150 sheep producers to identify production inefficiencies and to develop conservation plans. Producers will also modify management plans through technology implementation to mitigate emissions and improve their overall productivity. Enrolled producers will work with a Technical Service Provider (TSP) to establish operational plans, implement recommended changes and organize farm data to identify best management practices for productivity improvements. 

Enrollment Benefits

Producers enrolled in the program will be paid up to $23,000 to develop and implement improved sheep and land stewardship management plans. Additional enrollment benefits:

• Technical Service Provider
• Electronic livestock identification system
• Soil sampling
• NSIP ultrasound and genetic consulting services

Contractors for Implementation and Evaluation of Healthy Native Babies Project (HNBP) Materials

The CDC Foundation is re-releasing this RFP to allow for additional applicants to partner with us in this work. The CDC Foundation invites proposals from Tribes, Tribal Serving Organizations (TSOs), and Urban Indian Organizations (UIOs) [T/TSOs/UIOs] to implement and evaluate the updated Healthy Native Babies Project (HNBP) materials within their service areas. This initiative aims to strengthen culturally relevant infant safe sleep education, increase community awareness, and support Native families in reducing -sleep related- infant deaths. Selected T/TSOs/UIOs will adapt, disseminate, and assess the use of HNBP materials in ways that reflect the cultural, linguistic, and community-specific needs of the Native populations they serve. This project is a rapid turnaround project to support

T/TSOs/UIOs in:

• Implementing HNBP materials in clinical, community, and family setting.
• Training staff and community partners.
• Evaluating reach, effectiveness, and community feedback.
• Identifying barriers, facilitators, lessons learned, and best practices for future replication.

Funding Amount:

• Up to $100,000

Performance Period:

• May 18, 2026 to September 29, 2026

The Kidney Precision Medicine Project (KPMP), funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), aims to enhance research on Chronic Kidney Diseases (CKDs) and Acute Kidney Injuries (AKIs). Launched in 2017, this initiative focuses on ethical collection and analysis of human kidney tissue to uncover new molecular pathways. With expanded participant recruitment efforts beginning in 2022, the KPMP seeks to advance our understanding of kidney-related health issues.

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is extending the Kidney Precision Medicine Project (KPMP) for five years to enhance participant recruitment and tissue interrogation. This initiative aims to discover novel molecular pathways associated with Chronic Kidney Diseases (CKDs) and Acute Kidney Injuries (AKIs). The renewed funding will support robust longitudinal follow-ups for existing enrollees and facilitate the enrollment of new participants, ensuring comprehensive data analysis and collaboration within the research community.

The Kidney Precision Medicine Project Central Hub, funded by the National Institute of Diabetes and Digestive and Kidney Disease (NIDDK), aims to enhance our understanding of Chronic Kidney Diseases (CKDs) and Acute Kidney Injuries (AKIs). This initiative, which began in FY2017, focuses on ethically collecting and analyzing kidney biopsy tissues to uncover molecular pathways. The project was expanded in FY2022 to improve participant recruitment and tissue analysis, driving forward research in kidney health.

The Andrew Lloyd Webber Initiative offers Classroom Resources Grants aimed at enhancing theatre education in under-resourced public schools. Funded by a $1.3 million grant from the Andrew Lloyd Webber Foundation, the initiative provides essential resources, scholarships, and grants to foster artistic growth. By supporting diverse students and schools, this program opens pathways to careers in theatre, ensuring all young people have access to quality arts education, thereby enriching the cultural landscape of America.

About Pfizer Grants

Pfizer supports the global healthcare community’s independent initiatives (e.g., research, quality improvement or education) to improve patient outcomes in areas of unmet medical need that are aligned with Pfizer’s medical and/or scientific strategies.

Biochemical and Molecular Characterization of Marstacimab and TFPI Pathways 

This competitive grant encompasses research aimed at elucidating molecular and cellular mechanisms underlying marstacimab-TFPI interactions, including but not limited to differential expression of tissue factor and TFPI in various tissues, binding kinetics, and other biochemical properties. Projects should seek to advance foundational understanding of these interactions through innovative approaches in biochemistry, molecular biology, and related disciplines.

Project Types and Area of Interest

Projects that will be considered for Pfizer support will focus on basic science and fundamental biological understanding of Tissue Factor Pathway Inhibitor (TFPI), anti-TFPI Monoclonal Antibodies, and marstacimab. The areas of interest may include (but are not limited to):

• Basic biology of TFPI including interactions among key regulatory proteins in the intrinsic and/or extrinsic clotting cascades (e.g. Protein S being a co-factor for both Protein C and TFPI).
• Impact of differential TFPI expression within tissues and the role of various TFPI pools/isoforms in the regulation of coagulation.
• Pharmacology resulting from concomitant therapies added to anti-TFPI

Accreditation Sustainability Learning Community RFA

The Association of State and Territorial Health Officials (ASTHO), through the Public Health Infrastructure Grant (PHIG), is currently accepting applications for participation in a learning lab that will foster health department capacity to build a sustainable public health accreditation culture within their agencies. This opportunity is open to applicants from direct PHIG awardees at the state-, big city-, and county-level.

The Frederic C. Collin Trust Grant supports 501(c)(3) organizations in promoting polo and tennis, especially among youth. Established under Frederic C. Collin's will, it offers grants ranging from $2,000 to $3,800, with an annual total giving of approximately $9,000. Applications are accepted year-round for consideration during the annual grant meeting. This initiative aims to enhance participation in these sports, fostering talent and interest among young players.

Building Capacity for Communicating Impact Learning Community RFA

Learn how to communicate about Public Health Infrastructure Grant impact through a new community of practice! Through peer learning, technical assistance, and practical tools, participating teams will build strategic leadership and communications skills to more effectively translate public health achievements into compelling messages for key audiences. All directly funded PHIG recipients (big-city, county, state/territory-level governmental public health professionals) are eligible to apply.

Bridging the Gap Scholarship 

This scholarship was established to honor the memory of Trey Powell and Bridget Horn, who were both Veterans that lost their battle with PTSD to suicide. The Stronger Together Foundation strives to bring awareness to the large number of Veterans who face crises and ultimately commit suicide, as well as provide support to the families left behind. 

Scholarship Total Amount: $2,000.00

• (Two) $1,000.00 Scholarships will be awarded

The Alcon Foundation focuses on enhancing global eye health through charitable monetary donations to 501(c)(3) organizations. Grants aim to support programs that improve access to quality eye care and education, fostering community development. Eligible applicants must demonstrate high-quality services, well-defined goals, and the ability to report outcomes. The foundation does not fund organizations that discriminate or are not 501(c)(3) compliant, ensuring that resources are directed towards impactful initiatives.

At the Community Foundation for Muskegon County, we work with donors, grantees, and advisors to address key community issues.

Stanley C. and Maxine G. Sutherland Scholarship

This scholarship has been made possible by the generosity of Stanley Sutherland, Jr., who established the Stanley C. and Maxine G. Sutherland Scholarship of the Community Foundation for Muskegon County. Education was important to Maxine Sutherland. She graduated from Muskegon Junior College in 1940, received her nursing degree from the Hackley School of Nursing in 1942, and continued her education over the years until she received a B.S. in Education from Western Michigan University. Nursing was also important to Maxine, and over the years she was employed by Hackley Hospital, Visiting Nurses, and the office of her brother, Dr. Griffith. In her memory, her husband, Stanley Sutherland, Jr., has established the Maxine G. Sutherland Memorial , a donor advised , which will assist Muskegon County residents to pursue careers in nursing and other health related fields as well as support other projects and programs that were equally important to her.

The AO Spine NA Young Investigator Research Grant Award supports early-career surgeons and researchers focusing on clinically relevant spinal or spinal cord research. With funding of $20,000, this initiative encourages new investigators by providing essential start-up capital. Successful applicants are required to present their findings at the Annual AO Spine North America Fellows Forum and submit progress and final reports detailing their research outcomes. This grant aims to foster innovation and excellence in spinal care.

At the Community Foundation for Muskegon County, we work with donors, grantees, and advisors to address key community issues.

Sherman R. Poppen Scholarship

This scholarship has been made possible by the generosity of Sherman R. Poppen, who established the Sherman R. Poppen Scholarship of the Community Foundation for Muskegon County. Nancy Poppen was an artist who wanted children to explore and develop their talents in the fine arts. Prior to her death, in 1993, she established a fund in her name to provide "individualized arts opportunities" for Muskegon Public Schools students in grades three through 12. Her husband, Sherman Poppen, has watched the talents of over one hundred students develop over these last few years. Feeling the need to continue to support their talents, he established the Sherman R. Poppen Scholarship Fund to provide scholarships for Muskegon High School graduates who have participated in programs funded through the Nancy K. Poppen Fund. Now these students, pursuing arts studies at accredited colleges and universities or under the tutelage of master artists, can be assured of continued support and backing.

The Donald & Ruby Branson Foundation Grant aims to promote environmental, educational, and social progress in America. Established by the Branson family, it seeks to instill values of community involvement and charitable responsibility in future generations. The foundation primarily supports tax-exempt organizations under Section 501(c)(3) and emphasizes the importance of education and environmental stewardship, ensuring a cleaner and more attractive world for all.

Agog Open Call: Climate Futures + Immersive Media

This open call supports immersive media projects that help people better understand and respond to climate challenges and imagine what a better world could be.

We are looking for projects that use immersive technologies—including smart glasses, augmented reality, spatial sound, and mixed reality—to create more engaging, experiential forms of climate storytelling and civic participation.

The open call will support projects across a range of stages and formats, from early ideas to more developed work. What matters most is a compelling story or experience, a clear sense of purpose, and a thoughtful approach to bringing the work to life.

Grants may be awarded in denominations ranging from $25,000 to $200,000. In addition to funding, selected projects may receive mentorship, advisor support, and opportunities for partnership and distribution.

At the Community Foundation for Muskegon County, we work with donors, grantees, and advisors to address key community issues.

Rocket Scholars Foundation Scholarship

This scholarship has been made possible by the generosity of the parents and alumni of Reeths Puffer Schools, who established the Rocket Scholars Foundation Scholarship of the Community Foundation for Muskegon County. The Rocket Scholars Foundation was created by parents and alumni with two purposes in mind:

• To continue to foster within the school system a culture of rigorous academic achievement for all students and
• To offer those students who have demonstrated high achievement, scholarships to help defray the increasingly expensive tuition costs at colleges, universities and accredited post-secondary vocational and technical schools.

Residential Substance Abuse Treatment for State Prisoners (RSAT) Program

Overview

The Residential Substance Abuse Treatment (RSAT) Program is a formula grant program that enhances the capabilities of state, local, and tribal governments to provide residential substance use disorder (SUD) treatment to adult and juvenile populations during detention or incarceration, initiate or continue evidence-based SUD treatment in jails, prepare individuals for reintegration into the community, and assist them and their communities throughout the reentry process by delivering community-based treatment and other recovery aftercare services.

The RSAT Program encourages the establishment and maintenance of drug-free prisons and jails and development and implementation of specialized residential SUD treatment for individuals with co-occurring mental health and substance use disorders. The program also encourages the inclusion of medication-assisted treatment as part of any SUD treatment protocol.

Bureau of Justice Assistance

The Bureau of Justice Assistance (BJA) was created in 1984 to reduce violent crime, create safer communities, and reform our Nation’s criminal justice system.

BJA strengthens the Nation’s criminal justice system and helps America’s state, local, and tribal jurisdictions reduce and prevent crime, reduce recidivism, and promote a fair and safe criminal justice system. BJA focuses its programmatic and policy efforts on providing a wide range of resources, including training and technical assistance, to law enforcement, courts, corrections, treatment, reentry, justice information sharing, and community-based partners to address chronic and emerging criminal justice challenges nationwide. 

FY25 Residential Substance Abuse Treatment (RSAT) for State Prisoners Training and Technical Assistance Program

Executive Summary

This NOFO will provide training and technical assistance (TTA) to state and local grantees of the Residential Substance Abuse Treatment (RSAT) for State Prisoners Program to enhance implementation of comprehensive residential substance use treatment during detention or incarceration and aftercare services to prepare individuals for successful reintegration into the community. The selected TTA provider will also maintain and update the RSAT TTA website to serve as single source of information for RSAT grantees that reflects evolving needs and emerging evidence-based approaches.

Bass Pro Shops & Cabela's Outdoor Fund supports conservation-focused nonprofits through fundraising events and donation of merchandise or gift cards. Organizations eligible for funding must be registered 501(c)(3) entities in the U.S. or provincially registered nonprofits in Canada. This initiative aims to connect communities to outdoor activities while promoting wildlife conservation and support for military veterans. Grants of up to $1,000 are available to enhance local fundraising efforts.