Best Large Grants for Nonprofit Organizations in Wyoming

The Doris Duke Foundation's Environment Program grants aim to foster a resilient environment through effective conservation efforts. By supporting U.S. nonprofit organizations, the foundation seeks to protect biodiversity, address climate change, and advance equity, particularly for marginalized communities. The program emphasizes land conservation, natural climate solutions, and inclusive practices, ensuring that conservation efforts benefit both wildlife and people. This initiative is pivotal for enhancing the health of ecosystems and communities across the United States.

Columbia Basin Trust

The Trust was created in 1995 to support efforts by the people of the Basin to create a legacy of social, economic and environmental well-being in the Canadian portion of the Columbia River Basin—the region most affected by the Columbia River Treaty.

Mission: The Trust supports efforts by the people of the Basin to create a legacy of social, economic and environmental well-being and to achieve greater self-sufficiency for present and future generations.

Non-profit SMART Grants

Non-Profit SMART Grants support Basin non-profits and First Nations to increase their energy efficiency, generate renewable energy, adapt to the impacts of climate change, and/or reduce their greenhouse gas emissions.

There are two streams for this grant: Stream One – Electric Vehicles and Charging Stations; and Stream Two – Renewable Energy and Improvements to Buildings

Stream Two – Renewable Energy and Improvements to Buildings

This stream supports solar photovoltaic arrays, energy efficiency retrofits or other building improvements to structures or property.

Columbia Basin Trust

The Trust was created in 1995 to support efforts by the people of the Basin to create a legacy of social, economic and environmental well-being in the Canadian portion of the Columbia River Basin—the region most affected by the Columbia River Treaty.

Mission: The Trust supports efforts by the people of the Basin to create a legacy of social, economic and environmental well-being and to achieve greater self-sufficiency for present and future generations.

Non-profit SMART Grants

Non-Profit SMART Grants support Basin non-profits and First Nations to increase their energy efficiency, generate renewable energy, adapt to the impacts of climate change, and/or reduce their greenhouse gas emissions.

There are two streams for this grant: Stream One – Electric Vehicles and Charging Stations; and Stream Two – Renewable Energy and Improvements to Buildings

Stream One – Electric Vehicles and Charging Stations

This stream supports the purchase of one new electric or plug-in hybrid vehicle for use in Basin communities, and/or up to two charging stations.

The Roy A. Hunt Foundation's Environment Initiative Grants aim to support projects that enhance ecological health and sustainability. With an annual budget of approximately $3.4 million, the foundation prioritizes initiatives that promote responsible environmental practices, clean energy, and waste reduction. Grants between $25,000 and $75,000 are available for projects at various levels, focusing on innovative solutions that foster community partnerships and address root causes of environmental challenges.

Roche Corporate Donations and Philanthropy (CDP) focuses on impactful projects that foster sustainable development, engage employees, and leverage Roche's expertise. Their philanthropic efforts prioritize humanitarian, educational, environmental, and cultural initiatives, aiming to build stronger communities and support innovative projects. Eligibility is limited to local organizations, while ineligible projects include those with political or religious ties. The foundation strives to create a positive societal impact through collaboration and strategic partnerships.

Every Kindness is a Gift

Dollar Tree Gift Card Program 2026

Every Kindness is a Gift is a gift card grant program made possible through the generosity of Dollar Tree and managed by the team here at Gift Card Bank. We are a nonprofit organization that specializes in the distribution of gift cards and our mission is to improve well-being and build financial stability by supporting people through their time of need.

Through Every Kindness is a Gift, nonprofit organizations and Title I schools located in the 48 contiguous states may apply to receive a grant of Dollar Tree gift cards.

Gift cards received through these grants are meant to be distributed directly to individuals and families in need. A primary goal of the program is to give gift card recipients the dignity of choice by empowering them to shop for what they need themselves. By putting gift cards directly in the hands of our neighbors in need, we are able to increase access to essentials like food, school supplies, paper products, cleaning products, and hygiene items.

In 2026, there will be two rounds of grant distributions. In each round, we will award a number of grants between $2,500 and $10,000.

Round One is a summer distribution. Gift cards awarded in Round One will arrive in late June, while kids are on break and back-to-school is around the corner. Round Two is a holiday distribution. Gift cards awarded in Round Two will arrive in early November, as the end-of-year holidays approach.

We know that these are times of year when budgets are tight. Through these gift card grants, we hope to connect individuals and families directly to the essential resources they need during difficult months.

The Sigma Xi Grants-in-Aid of Research Program, celebrating 100 years of supporting research, offers financial assistance to undergraduate and graduate students. Members can receive grants ranging from $500 to $5,000, while non-members can apply for up to $1,000. Additionally, there are specific funds available for astronomy and vision-related research. This program fosters collaboration between students and mentors, promoting scientific excellence through hands-on experience.

The Growing Healthy Kids Grant, funded by The Sprouts Healthy Communities Foundation, aims to support community-based programs that enhance children's nutrition access and health education. With grant amounts ranging from $5,000 to $10,000, this initiative focuses on hands-on programs that promote healthy habits among children and their families. Eligible organizations must be 501(c)(3) nonprofits located in areas where Sprouts Farmers Market operates, helping to ensure that the funds directly benefit local communities.

The FY26 Bureau of Land Management Youth Conservation Corps program aims to engage youth aged 16-30, including veterans and tribal members, in hands-on conservation projects. These initiatives foster skills in natural resource management, promote public land stewardship, and enhance community involvement through trail building, habitat restoration, and cultural resource preservation. By partnering with qualified youth corps, the program supports economic growth and environmental health while preparing the next generation of public land stewards.

The Wyoming Nonpoint Source Program, part of the WDEQ, aims to enhance water quality through voluntary pollution reduction efforts. It provides $40,000-$80,000 annually via Section 205(J) grants to local agencies for planning and assessment projects, prioritizing efforts in watersheds affected by impaired waterbodies. This initiative encourages collaboration among landowners and various government entities to effectively tackle nonpoint source pollution, which is challenging to identify and manage.

The Wyoming Nonpoint Source Program, part of the WDEQ's Watershed Protection Program, aims to preserve and restore water quality through voluntary pollution reduction projects. Funded by the Section 319 grant, it allocates nearly $1 million annually to support local entities in implementing effective nonpoint source pollution solutions. These initiatives are prioritized based on water quality needs identified by the WDEQ, fostering collaboration among landowners, groups, and government agencies to enhance watershed health.

The WY Community Forestry Grants support the development and enhancement of community forestry programs in Wyoming. Aimed at fostering partnerships among government, businesses, and volunteers, the program offers funding for tree planting, educational projects, and community forestry development. Eligible projects must involve volunteers and can include workshops, tree inventories, and maintenance plans. Funding is available through three grant categories, ensuring a collaborative approach to improving urban forests across the state.

The J.R. Simplot Company Foundation Grant supports U.S. non-profit organizations focused on art, education, youth, community, and global food and agriculture. Established in 1929, the foundation is committed to enhancing community welfare through creative cultural endeavors, educational initiatives, health services, and youth programs. Applications are reviewed quarterly, ensuring a timely response to organizations dedicated to making a positive impact in their communities.

The Diminished Tree Species Grant Program focuses on restoring native tree species crucial for biodiversity and forest health. By funding scientific research, seed orchard development, and land preservation, the program aims to combat climate change through effective tree restoration projects. The Oak Hill Fund, a private entity, encourages project-specific applications, prioritizing organizations that meet eligibility criteria under Section 501(c)(3) of the IRS. This initiative is vital for sustaining healthy ecosystems and mitigating environmental impacts.

The True Inspiration Awards, established by Chick-fil-A in 2015, recognizes nonprofit organizations that significantly impact their communities. In 2025, the program will distribute $6 million in grants, ranging from $30,000 to $350,000, to sixteen selected organizations. Categories include Caring for People, Caring through Food, Community, and Caring for our Planet, with a focus on educational initiatives, food security, housing services, and environmental stewardship, honoring the legacy of founder S. Truett Cathy.

The Sorenson Legacy Foundation Grant aims to improve lives through support for education, health care, community development, and innovation. Established by James and Beverley Sorenson, the foundation focuses on enhancing art education, medical technologies, and community assistance in Utah. It prioritizes projects that foster artistic growth, promote innovative solutions, and address health care challenges while aiding vulnerable populations. The foundation's commitment to enriching lives reflects a deep-rooted belief in the power of education and community engagement.

The Working Here Fund Grant supports nonprofit organizations in Iowa, Nebraska, South Dakota, and Wyoming, providing funding options tailored to rural community needs. With a focus on agricultural education, hunger relief, and disaster assistance, the program has awarded over $13.5 million since 2013. Grants range from $5,000 to $25,000, with eligibility for organizations demonstrating alignment with FCSAmerica's mission. Priority is given to IRS 501(c)(3) nonprofits, fostering sustainable solutions for local challenges.

The Meg and Bert Raynes Wildlife Fund provides annual grants ranging from $3,000 to $5,000 to support wildlife research, citizen science, and educational initiatives in Jackson Hole and the Greater Yellowstone Ecosystem. Focused on lesser-known species, the fund aims to foster new research and the careers of emerging wildlife professionals. Eligible applicants include 501(c)(3) non-profits and educational institutions, emphasizing collaboration and measurable project outcomes.

The Therapeutic Giving initiative by Johnson & Johnson focuses on funding programs in neuroscience aimed at enhancing patient access to treatments and promoting health equity. Nonprofit organizations classified as 501(c)(3) can apply for support from March 1 to May 31. The initiative emphasizes innovative, measurable programs in areas like Alzheimer’s disease and mental health, prioritizing those that address healthcare disparities and improve quality of life for affected individuals.

The Therapeutic Giving program from Johnson & Johnson Innovative Medicine aims to support local and regional organizations focused on improving patient access to treatment and advancing health equity. Eligible applicants include 501(c)(3) nonprofit organizations, with funding preferences for programs that address significant healthcare disparities, mental health initiatives, and innovative solutions with measurable outcomes. The application period for local organizations runs from March 1 to May 31, while national organizations can apply in September.

The Doyle Undergraduate Fellowship, offered by New Hampshire Sea Grant, provides a unique opportunity for undergraduates to engage in marine resource projects while receiving mentorship and training. This paid fellowship supports students interested in marine-related research and education, with potential earnings of up to $5,000 over a 10-week summer period. By participating, fellows gain valuable insights into coastal and marine management, enhancing their skills and expanding their professional networks.

The Therapeutic Giving: Oncology program by Johnson & Johnson focuses on funding initiatives that enhance patient access to treatments and services, promote health equity, and strengthen healthcare workforces. It supports programs that raise disease awareness, empower patients, and improve health systems with measurable outcomes. Eligible applicants include nonprofit organizations with 501(c)(3) status, emphasizing innovative programs addressing healthcare disparities and unmet needs.

The U.S. Healthcare Donations program by Amgen aims to support not-for-profit organizations in the healthcare sector. As a leading biotechnology company, Amgen provides funding for initiatives that improve science, technology, education, and public awareness on medical conditions. Organizations eligible for funding must be tax-exempt entities, focusing on genuine philanthropic efforts that align with Amgen's mission to enhance health outcomes and reduce the burden of diseases.

The Entergy Charitable Foundation Grant focuses on supporting initiatives that foster thriving communities through education, poverty solutions, and environmental programs. The foundation prioritizes funding for 501(c)(3) organizations and similar entities. Key areas include education development, innovative poverty solutions, and environmental restoration efforts, such as coastal wetland preservation. Organizations are encouraged to apply at least three months before funding is needed, ensuring timely support for impactful community projects.

The Rural Initiative Grant Program by the Laura Jane Musser Fund aims to foster collaboration among rural communities in areas like economic development and education. Emphasizing community involvement, it encourages diverse participation and measurable outcomes within 18 months. Grants of up to $25,000 for implementation or $5,000 for planning are available, targeting nonprofit organizations and local governments in select states. This initiative seeks to empower communities to achieve positive change through active engagement and support.

The Title XVI Water Reclamation and Reuse Projects, funded by the US Department of the Interior's Bureau of Reclamation, invites proposals for innovative water reuse solutions. This program enhances water supply reliability and supports sustainable practices for urban and agricultural communities. By leveraging Federal and non-Federal resources, the initiative aims to address water scarcity and improve hydropower reliability, aligning with national priorities for energy and resource management.

The WaterSMART: Desalination Construction Projects initiative by the Bureau of Reclamation aims to enhance water supply reliability through cooperative funding and support for desalination facilities. This program aligns with federal priorities to improve energy and resource management, encouraging proposals that diversify local water sources. By focusing on innovative solutions to water scarcity, the initiative promotes sustainable water management practices, especially for growing communities facing water shortages.