Best Large Grants for Nonprofit Organizations in Wyoming

The American Indian College Fund offers scholarships for non-Tribal college students, providing financial support for American Indian and Alaska Native students pursuing higher education at accredited institutions. Applications open annually on February 1st, with a priority deadline of May 31st. Award amounts typically range from $2,000 to $3,000. Students are encouraged to apply early to ensure priority review for available scholarships, fostering educational opportunities and success for Indigenous youth.

The Nick Andros Music Scholarship, established by the family and friends of Nick Andros, honors his passion for music and positive inspiration. This scholarship seeks to support students who demonstrate Nick's spirit through their dedication to the arts. Eligible candidates must be high school seniors from Saginaw County with a minimum GPA of 2.0, pursuing an undergraduate degree. Applicants are required to submit an MP3 of their work, showcasing their musical talents.

The Family Unification Program (FUP) aims to assist families and youth at risk of homelessness by providing Housing Choice Voucher (HCV) assistance. It targets families facing housing issues that could lead to out-of-home placement for children and youth aged 18-24 who have aged out of foster care. The program offers flexible voucher durations, with extensions available under specific conditions, ensuring support for those in need of stable housing.

The MSA Climate Change Research Award, offered by the Mycological Society of America, supports innovative research addressing the impacts of climate change through the lens of fungal studies. Ideal candidates include undergraduates, graduate students, and post-doctoral scientists who are MSA members or have applied for membership. This award encourages collaboration and aims to disseminate research findings to the global scientific community, fostering inclusivity across various demographics.

The Samuel "Eric" Storm Memorial Scholarship Fund offers $2,500 to students pursuing advanced degrees in Physical Therapy, Occupational Therapy, or Speech Therapy. Established in honor of Eric Storm, a dedicated physical therapist, the fund aims to support students in accredited programs. Eric's legacy includes his commitment to mentorship and community service, reflecting his belief in health care as a calling. This scholarship honors his impact on many lives and encourages future health professionals to follow in his footsteps.

The Disaster Grants Program by LSC provides vital funding to organizations aiding survivors of government-declared emergencies. It empowers legal aid groups to deliver essential services to low-income disaster survivors, ensuring access to legal assistance during crises. The program also educates communities on disaster legal services and prepares them for future emergencies, enhancing resilience and response capabilities. By supporting various grant types, the initiative addresses immediate needs and fosters long-term recovery strategies.

The Arthritis Foundation is seeking research proposals focused on Patient Reported Outcomes (PROs) to enhance shared decision-making in arthritis care. Projects should aim to deepen the understanding of patient treatment goals, monitor disease activity, and improve communication of PRO data. Research can span various arthritis types, including osteoarthritis and rheumatoid arthritis, and should last up to two years. This initiative emphasizes the integration of patient perspectives to elevate care quality.

The Racial Equity & Women’s Intercultural Ministries Grants and Scholarships, supported by the Presbyterian Mission Agency, aim to empower leaders, congregations, and organizations that promote racial equity and women's rights. This initiative reflects the Presbyterian Church's commitment to justice and inclusivity, fostering an environment where diverse voices can thrive and contribute to the community. By providing these resources, the program seeks to uplift marginalized groups and promote social equity within faith-based settings.

The Youth Regional Treatment Center Aftercare Program aims to support American Indian and Alaska Native youth in maintaining safety, sobriety, and success post-discharge from Youth Regional Treatment Centers. This initiative enhances culturally relevant, community-based aftercare by fostering care coordination, building partnerships, and addressing barriers to improve youth outcomes.

The Robert J. Keown Trust, established in 1934, provides financial assistance to needy Christians through grants to charitable organizations. Managed by Wells Fargo Bank N.A., the trust focuses on supporting organizations that benefit residents of Los Angeles County. Eligible organizations must be 501(c)(3) exempt. Preference is given to requests aiding needy Christians and elderly women. The trust awards an average of four grants per year, fostering community support and outreach.

The James B and Lois R Archer Charitable Foundation offers Smaller Grants of $10,000 or less to support initiatives in Arts and Culture, Civic Engagement, Education, Health, and Human Services. Organizations must have 501(c)(3) status and comply with eligibility criteria, including a one-year waiting period for reapplications. The foundation aims to have a significant impact on communities, especially in West Texas, while avoiding funding for specific exclusions such as endowments and fundraising events.

The James B and Lois R Archer Charitable Foundation offers Large Grants for requests exceeding $10,000. Focused on fostering positive change, the foundation supports initiatives in Arts and Culture, Civic Engagement, Education, Health, and Human Services. Eligibility includes 501(c)(3) organizations, while restrictions apply to consecutive grant cycles and non-qualifying purposes such as endowments and fundraising events. Organizations are encouraged to apply for various projects to enhance community well-being.

The Clinical Research Training Scholarship in Parkinson's Disease, funded by the Parkinson's Foundation and the American Brain Foundation, supports young investigators in clinical studies related to Parkinson's disease. Offering $65,000 annually for two years, plus an additional $10,000 for education and research costs, this award aims to foster rigorous clinical research. Eligible applicants must have an MD, PhD, or equivalent degree and be AAN members, focusing on patient-oriented research with human subjects.

The NIA Expanding Research in AD/ADRD Postbaccalaureate Research Education Program aims to enhance the research workforce by providing intensive research experiences for recent graduates. This initiative supports early-stage investigators in Alzheimer's Disease and related dementias, addressing a critical shortage of researchers in the field. Participants engage in independent research, mentorship, and professional development, equipping them with skills necessary for advanced degrees and research careers in aging and dementia. The program fosters innovation and interdisciplinary collaboration essential for advancing AD/ADRD research.

The Clinical Data, Safety and Statistical Centers (CDSSC) program, supported by the National Institute of Allergy and Infectious Diseases (NIAID), aims to enhance clinical research through comprehensive support. This includes statistical analysis, protocol development, and oversight of safety monitoring in studies related to asthma, autoimmune diseases, and transplantation. By coordinating these efforts, the program seeks to facilitate impactful research outcomes and improve public health outcomes through informed data-driven decisions.

The BioMarin Grant aims to support events, activities, and projects that enhance public health and benefit patients with rare diseases. This corporate funder focuses on scientific innovation and provides resources for organizations such as hospitals, universities, and patient advocacy groups. With an emphasis on education and community support, BioMarin encourages applications for funding throughout the year, ensuring timely assistance for eligible projects.

The Marlene and Spencer Hays Foundation Grants support tax-exempt organizations working to enhance lives through arts, healthcare, education, and youth programs. The foundation requires a Letter of Intent (LOI) from all applicants, emphasizing its mission to select grant recipients who align with its values. Grants are not available for political purposes, endowment campaigns, or organizations that discriminate based on race, gender, or religion. This framework ensures a focused impact on community betterment.

The ASTRO-AstraZeneca SCLC Therapy Challenge RFP aims to enhance research on limited-stage small cell lung cancer (LS-SCLC) through innovative combination therapies, particularly integrating immunotherapy with advanced radiation techniques. Proposals are encouraged to explore various aspects, including care patterns, treatment workflows, prognostic biomarkers, and toxicity management. The target budget for projects ranges from $175,000 to $375,000, with consideration given to higher requests based on scientific merit, fostering significant advancements in radiation oncology.

The Bertin Family Foundation Grants support 501(c)(3) public charities that align with the foundation's mission of community strengthening and compassion. Grant requests are accepted annually from July 1 to August 31, focusing on program or project support rather than general endowment. The foundation values measurable outcomes and responsible stewardship, and gives preference to organizations with Gold or Platinum status on Candid.

Tree and Soil Research Fund Grant Program

The TREE Fund Board of Trustees is launching the new Tree and Soil Research Grant, made possible by a permanently restricted endowment fund supporting areas of research of interest to the landscape architecture community with special focus in the area of trees and the soils that support them. Projects are expected to be completed within one to three years, with a maximum award value of $10,000. No project may receive more than one award from this program. This grant will be offered every other year beginning in 2021.

Award amount:

• up to $10,000 (minimum $5,000) 

The Maternal, Infant, and Early Childhood Home Visiting Program (MIECHV) aims to enhance maternal and child health, promote early childhood development, and support family well-being. By providing voluntary, evidence-based home visiting services to pregnant women and families with young children, the program addresses critical needs in communities. Funded by the US HHS: Health Resources & Services Administration (HRSA), MIECHV empowers families through tailored support and resources, fostering healthier outcomes for mothers and their children.

The Bloomberg Green Docs Contest invites filmmakers to create impactful short documentaries addressing climate change. Competing for a grand prize of $25,000, participants are encouraged to showcase urgent narratives about our climate future. The films should be under 10 minutes, including credits, and highlight both restoration efforts and the challenges posed by climate extremes. Winners will be revealed at the Bloomberg Green Docs Film Festival, making this a pivotal opportunity for storytellers passionate about environmental issues.

The Manning Family Foundation offers Health and Life Sciences Research Grants to support innovative research aimed at finding effective treatments and cures for diseases like diabetes and macular degeneration. Since 2003, they have funded 501(c)(3) nonprofits that contribute to these fields, emphasizing entrepreneurialism and impactful research. Applications are accepted on a rolling basis, with awards given three times a year, fostering advancements in health and community well-being.

The Juan Diego Guadiana Legacy Foundation Scholarship supports students from Las Cruces High School or Doña Ana County, especially those affected by cancer treatment or pursuing health-related fields. This scholarship is open to various backgrounds, including BiPOC and LGBTQIA+ communities. The foundation aims to empower students at different educational stages, ensuring they have the resources necessary to thrive in their academic and professional journeys.

The CAFE Group 

We resource leaders, invest in their genius, and bring people together to reimagine what philanthropy can do.

Founded by Liz and Don Thompson, The CAFE Group is a national nonprofit transforming how change is resourced. 

With a focus on education equity, social capital, and philanthropic transformation, we pair catalytic funding, community-rooted leadership development, and cross-sector collaboration to strengthen the people and institutions shaping a more just future. Everything we do is grounded in relationship, because we believe the way resources move matters just as much as where they land.

The 1954 Project Luminary Award

The 1954 Project Luminary Award celebrates transformational education nonprofit leaders dedicated to serving Black students and communities through powerful investments in their organizations' ability to create lasting change.

The Luminary Experience

Each Luminary organization gets more than funding. Through The 1954 Project, leaders gain a community, a platform, and space to grow with tailored support over the course of the three year journey.​

• $1 Million, Unrestricted: Catalytic funding to expand what’s working.
• Leadership Coaching + Capacity Support: Guidance from peers and experts who are committed to helping you build a lasting, impactful organization.
• National Network: Luminaries join a powerful community of innovators, change-makers, and visionaries driving systemic progress to support students and communities across the U.S.

The 1954 Project’s Impact Areas

We focus on three interconnected areas critical to advancing equity:

• Innovation in Teaching and Learning: Create education models that center Black students through culturally affirming approaches that challenge traditional structures and transform how learning happens, ultimately serving all students. 
• Diversity in Education: Build pathways that increase and sustain Black educators and education leaders who transform where and how students learn.
• Pathways to Economic Mobility: Build pathways to wealth, ownership, and economic power for Black students, families, and communities through innovative educational programming.

Our Selection Criteria

We seek out extraordinary applicants who embody our values and vision across three categories:

Leader: We look for leaders whose influence and vision contribute to the collective well-being and advancement of the Black community. These leaders:

• Are Visionary: They demonstrate a strategic and pragmatic mindset, articulating a transformative vision for significant, positive change.
• Show Demonstrated Commitment: They embody steadfast dedication to your cause, inspiring and influencing others, and galvanizing community involvement.
• Are Adaptive: They assertively tackle challenges, turning setbacks into opportunities for innovation, while maintaining humility and thoughtfulness in problem-solving.

Organization: We look for organizations that drive significant change, anchored by a deep love for people and driven by the genius within communities of color. These organizations: 

• Have a Defined Problem: They clearly identify the issue they are addressing and explain in detail how your organization tackles root causes. 
• Take a Strategic Approach: They have clear, measurable, and achievable organizational goals with a well-defined strategy informed by thorough analysis. 
• Show Demonstrated Impact: They have a tested model that has produced positive results, incorporating continuous learning and iteration. 
• Have a Transformation Plan: They present a clear plan for using the $1M award to advance your organization's mission, vision, and long-term goals. 
• Embrace Collaboration: They use collaborate to build partnerships based on trust, love, and common goals. 

Radical Imagination: We seek leaders who challenge and redesign societal norms to build a just and equitable future. They demonstrate:

• Community-Rooted Leadership: They maintain and cultivate genuine community ties, integrating professional expertise and personal commitment to drive visionary, impactful strategies. 
• Long-Term Commitment: They are in it for the long haul, committing to sustained impact across generations and prioritizing long-lasting solutions over short-term gains. 
• Collectivism: They embody the philosophy of "I am because we are," actively engaging in collaborative networks and fostering community-reflective solutions. 

The Thomas Halbert Scholarship, administered by the Community Foundation of the Ozarks, offers a $1,400 scholarship to undergraduate nursing students enrolled in accredited colleges in Springfield, MO. Applicants must demonstrate financial need through FAFSA and provide a transcript showing a minimum GPA of 3.0. An essay submission is also required. This initiative reflects the foundation's commitment to enhancing community quality of life through education and support.

Research Grant Program 

Providing research grants to support clinicians and scientists focused on primary immunodeficiency (PI).

Scope and eligibility

• The Immune Deficiency Foundation's Research Grant Program supports patient-centered research focused on improving the treatment, health, disease management, or diagnosis of people with primary immunodeficiency (PI), as well as research that contributes to the broader body of knowledge on PI.
• Awards range from $25,000-50,000. In addition, the Michael Blaese Research Grant Award is bestowed on the highest-scored application each cycle.
• One-year term.