Best Grants for Grassroots Organizations in Alabama

The PNC Foundation's Grow Up Great Grant is a significant initiative aimed at enhancing educational opportunities for children from birth to age 5. With a commitment of $500 million, this program focuses on improving school readiness through support in vocabulary development, social-emotional learning, and the arts. By partnering with community-based nonprofits, PNC aims to foster stronger, smarter, and healthier communities, ensuring a brighter future for the next generation.

About Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Who we are and our impact

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Multiple sclerosis (MS)

Help with healthcare costs for Multiple sclerosis (MS)

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

About the disease

Multiple sclerosis (MS) is a potentially disabling disease of the central nervous system in which the insulating covers of the nerve cells in the brain and spinal cord are damaged. MS is a chronic disease that affects the nervous system.

Pinky Swear Foundation

Our mission

Pinky Swear Foundation's mission is to help kids with cancer and their families with financial support. 

All-Star Fund

Housing, food, and transportation support

The All-Star Fund provides financial support for everyday expenses to families navigating the challenging journey of childhood cancer. This fund provides assistance for rent/mortgage, utility payments, groceries, gas, and car payments, ensuring that families can focus on what truly matters - their child.

Building the Future Workforce Challenge

Awarding $5 million and the opportunity to test bold, tech‑forward solutions that strengthen the advanced manufacturing and industry technician workforce—today and for the future.

About the Challenge

Caterpillar knows preparing the workforce for the future is urgent. Communities, employers, and industry need new ways to close advancing skill gaps. The Building the Future Workforce Challenge invites fresh perspectives from all sectors to rethink training. Up to five teams will be awarded $1 million each for sustainable, tech‑forward solutions that strengthen today’s—and tomorrow’s—advanced manufacturing and industry technician talent pipelines.

What types of solutions are you looking for?

The Building the Future Workforce Challenge aims to identify, test, and scale innovative, sustainable solutions that will address today’s and tomorrow’s advanced manufacturing and industry technician skill gaps. A core requirement of any solution is that it remains relevant amid evolving technology—ensuring that breakthrough innovation and human potential rise together.

Strong proposals for Building the Future Workforce Challenge will meet four criteria outlined in the scoring rubric, and proposed solutions must focus on one or more of the following solution categories for Building the Future Workforce Challenge:

About Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Who we are and our impact

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Multiple sclerosis (MS) health equity

Help with healthcare costs for multiple sclerosis (health equity)

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

Health Equity Funds offer help to eligible patients living in areas identified as having increased social and financial needs, as well as higher rates of chronic conditions. Eligibility is determined in part by home address zip code. 

About the disease

Multiple sclerosis (MS) is a potentially disabling disease of the central nervous system in which the insulating covers of the nerve cells in the brain and spinal cord are damaged. MS is a chronic disease that affects the nervous system.

The Imagine Learning Foundation's Signature Grant Program aims to enhance the well-being of learners by supporting social and emotional learning (SEL) initiatives. By bridging classroom and community efforts, it fosters healthier environments for youth, families, and educators. The program prioritizes funding for organizations addressing critical issues like chronic absenteeism and housing insecurity. In 2024, the foundation will allocate over $400,000 to impactful projects, furthering its mission to cultivate supportive learning experiences both in and out of the classroom.

Truist Foundation

The Truist Foundation is committed to Truist Financial Corporation's (NYSE: TFC) purpose to inspire and build better lives and communities. Established in 2020, the foundation makes strategic investments in nonprofit organizations to help ensure the communities it serves have more opportunities for a better quality of life. The Truist Foundation's grants and activities focus on building career pathways to economic mobility and strengthening small businesses.

Inspire Awards

This year’s Inspire Awards seeks nonprofits supporting the career navigation and workforce development needs of workers across the United States. The challenge seeks applications that help individuals gain the skills, guidance, and support needed to access quality jobs, advance in their careers, and build long-term stability in an evolving world of work.

2026 Truist Foundation Inspire Awards Challenge Question

How are nonprofits providing innovative direct services, training programs, and career navigation supports for adult workers in the age of AI?

Challenge Dimensions

Nonprofit organizations have long been critical advocates and service providers for workers in the United States. Nonprofits provide workers necessary upskilling opportunities, AI literacy training, career navigation support, and wraparound services in conjunction with career pathways programming. All necessary for the modern workforce. Meeting the moment, Truist Foundation and MIT Solve want to hear the ways in which nonprofits headquartered in the Truist operating footprint are providing innovative career pathway programming in the age of AI. Although solutions don’t need to focus on generative AI specifically, teams should demonstrate how their career pathways programming align with the following dimensions:

• Training and Upskilling Programs – Providing holistic, accessible programming that equips workers with essential skills, industry-validated credentials, and technical literacy for the modern workplace.
• AI Readiness and Literacy – Offering high-quality training that helps workers understand generative AI and agentic technologies as augmented intelligence tools, helping to build practical skills like effective prompting, domain expertise application, and ethical use.
• Additional Wraparound Services and Basic Needs Support – Supporting unemployed and underemployed workers on their journey to economic mobility through comprehensive, integrated resources including childcare, transportation support, mentorship, mental health services, benefits navigation, and more.
• Career Navigation in the AI Economy – Enabling workers to navigate career choices with clarity and confidence by providing accessible information about how AI is reshaping job roles and industries, facilitating informed decisions about high-quality career trajectories that align with individual circumstances, and connecting workers to industry-validated credentials or trainings.

Here are the grants for this challenge

• First place: $250,000
• Second place: $150,000
• Runners-up: $25,000
• Audience favorite: $75,000

The Utility Arborist Research Fund Grant Program, managed by the TREE Fund and UAA, offers $50,000 in funding for 2024 to support vital research in utility tree care. The program prioritizes proposals focusing on employee safety, service reliability, and regulatory compliance. Grants range from $10,000 to $50,000, with the aim of addressing pressing issues in vegetation management. Applications are welcomed from those aligned with these priorities, promoting safety and efficiency in the utility industry.

The Congenital Sucrase-Isomaltase Deficiency Fund, managed by the HealthWell Foundation, aims to alleviate financial burdens for underinsured patients suffering from this genetic disorder. By providing assistance with prescription drugs and treatment costs, the fund ensures that vital medications are accessible, allowing patients to manage their condition effectively. In 2024, the Foundation is expected to award over $1.2 billion in grants, showcasing its commitment to enhancing healthcare access for those in need.

The Chronic Lymphocytic Leukemia Fund, managed by the HealthWell Foundation, aims to alleviate financial burdens for underinsured patients battling chronic lymphocytic leukemia (CLL). This fund provides essential support for prescription copays and premiums, ensuring that patients can access necessary treatments without the stress of financial constraints. Since its inception, the foundation has awarded over $1.2 billion in grants, helping more than 1.1 million patients. The initiative emphasizes the importance of accessible healthcare and aims to improve the quality of life for those affected by this condition.

The Tick-borne Pathogen Award, sponsored by Bay Area Lyme Foundation, offers $150,000 to support innovative research on non-Borrelia tick-borne pathogens. This grant aims to attract scientific talent to explore co-infections with Lyme disease and other related infections. Eligible candidates include researchers from academia or the private sector at the post-doctoral level or higher, with a focus on improving diagnostics and therapies for tick-borne diseases. Applications must present a viable proof-of-concept project.

The Hearst Foundation's Health Grant aims to support nonprofits that enhance healthcare access for underserved populations in the U.S. Focused on improving skills and increasing healthcare practitioners, the grant also emphasizes public health and medical research. With a history of funding significant projects, the foundation prioritizes programs that address the complex needs of low-income, rural, and elderly communities. This commitment ensures a sustainable impact on national health outcomes while supporting innovative healthcare delivery systems.

CDC Foundation

The CDC Foundation helps the Centers for Disease Control and Prevention (CDC) and the public health system save and improve lives by unleashing the power of partnerships to protect the health, safety and security of all communities, everywhere. The CDC Foundation is authorized by Congress to mobilize philanthropic partners, corporations, organizations and individuals to support the critical health protection mission of CDC and the public health system.

The CDC Foundation manages hundreds of programs each year aimed at protecting communities across the country from a variety of health threats—from chronic disease conditions including cardiovascular disease and cancer, to infectious diseases like malaria and HIV to emergency responses, such as Ebola and Zika.

Contractor for Implementation and Evaluation of Healthy Native Babies Project Materials

The CDC Foundation invites proposals from Tribes, Tribal Serving Organizations (TSOs), and Urban Indian Organizations (UIOs) [T/TSOs/UIOs] to implement and evaluate the implementation of the updated Healthy Native Babies Project (HNBP) materials within their service areas. This initiative aims to strengthen culturally relevant infant safe sleep education, increase community awareness and support Native families in reducing sleep related infant deaths. Selected T/TSOs/UIOs will adapt, disseminate and assess the use of HNBP materials in ways that reflect the cultural, linguistic and community-specific needs of the Native populations they serve.

The Native Forward Scholars Fund Internship Assistance Program empowers Native students by providing financial support for internships in non-STEM fields. This initiative breaks down financial barriers, enabling students to gain practical experience in areas like public policy, education, and cultural preservation. Through this program, students enhance their skills while contributing positively to their Tribal communities. The funding covers essential costs such as travel and living expenses, ensuring transparency and accountability in financial assistance.

The Homeless Veterans' Reintegration Program (HVRP) aims to assist veterans experiencing homelessness by providing tailored employment services. This federal initiative focuses on helping veterans transition to stable employment through job training, case management, and connections to local supportive services. HVRP aligns with national priorities to enhance career outcomes for veterans, ensuring they receive the necessary tools and resources for sustainable employment and integration into the workforce.

The BIE Professional Development Funding for STEM Educators and Students, offered by the Native Forward Scholars Fund, supports training opportunities in science, technology, engineering, and mathematics (STEM) for TCU faculty, staff, and students. This funding assists with costs related to professional development including continuing education, conferences, and certifications. Eligible applicants include educators at BIE-funded or controlled schools, as well as those at institutions with significant Native American populations, fostering increased representation and support for Native scholars.

The Big Bald Dave Adventure Scholarship, provided by the Yellowstone Club Community Foundation, honors Dave Mueller's passion for outdoor adventure. It offers a unique summer trip for Big Sky students in grades 9-11 who demonstrate leadership and a love for the outdoors. Supported by Adventures Cross Country, this scholarship is a wonderful opportunity for students to engage in enriching experiences while giving back to the community. Notably, it is not based on financial need.

The SAF National Awards Program honors individuals in forestry for their innovative contributions to diversity and inclusion. Notably, the Cultural and Community Engagement Award recognizes SAF members who exemplify leadership in these areas. This award not only includes a $500 honorarium but also offers complimentary registration to the SAF convention and additional funds for travel. It highlights the importance of fostering an inclusive culture within the forestry profession.

Mr. Holland’s Opus Foundation

Who knew that a movie made 30 years ago would become the catalyst for the creation of a namesake non-profit, changing the lives of hundreds of thousands of kids by giving them access to learn and play music in school – keeping music education alive and strong across the country?

Mr. Holland’s Opus Foundation was inspired by the acclaimed motion picture Mr. Holland’s Opus, the story of the profound effect a dedicated music teacher had on generations of students. Michael Kamen, who wrote the score for the film, started the foundation in 1996 as his commitment to the future of music education.

The Foundation donates high-quality musical instruments to deserving, under-funded music programs, and provides an array of support services to school districts. By increasing the school’s inventory of quality, playable instruments, music teachers are given the tools they need to deliver a quality music education to students who want to learn. In collaboration with committed school districts, the Foundation’s investments are strategically placed as part of a K–12 district-wide plan to achieve positive and lasting results. Generations of students will benefit.

Instrument Grants

Mr. Holland’s Opus Foundation donates musical instruments to schools nationwide with a focus on increasing student access to music education programs in low-income communities.

Mr. Holland’s Opus Foundation grants consist of musical instruments and equipment only; no cash grants are provided. Our team handles sourcing, ordering, and delivering the instruments. As part of the application process, we work with the teacher to assess the program’s needs to determine the appropriate instruments and equipment. Note that only student model instruments are provided, and the brand is at the Foundation’s discretion.

Hungry for Music

The Hungry for Music story began in 1992, when Founder and Director Jeff Campbell (in photo) organized a street musician concert to benefit the homeless. Within three years, he formed a 501(c)(3) nonprofit organization, dedicated to expanding opportunities in music for children.

Since then, Hungry for Music has placed more than 27,000 instruments into the hands of aspiring musicians. Children whose trajectory has been altered by the uplifting and life-changing gift of music.

We've delivered everything from guitars and trombones to violins and xylophones to kids in 50 states and 35 countries.

We collect and redistribute more than 2,000 instruments annually and, in our 31-year journey, we've become a full-time force for good in the musical community.

Request an Instrument

Hungry for Music collects and distributes instruments including brass, woodwinds, strings, electric keyboards, drums and other percussion, as well as amps and accessories.

Who Hungry for Music Helps

• Music teachers at Title One schools who identify children who cannot participate because of lack of funding.
• Music directors at innovative after-school music programs.
• Social workers who have young clients who would benefit from music therapy.

We only accept requests from public school music teachers, administrators, after-school/summer music program directors, and social workers. 

In our history, we have supported music programs in 40 different countries through stateside sponsors (i.e. business, school, church). We do not accept requests directly from international programs.

Social Workers & School Counselors

Social workers and school counselors can submit a request application for a student if they have access to instruction through a music program. 

Hungry for Music

The Hungry for Music story began in 1992, when Founder and Director Jeff Campbell (in photo) organized a street musician concert to benefit the homeless. Within three years, he formed a 501(c)(3) nonprofit organization, dedicated to expanding opportunities in music for children.

Since then, Hungry for Music has placed more than 27,000 instruments into the hands of aspiring musicians. Children whose trajectory has been altered by the uplifting and life-changing gift of music.

We've delivered everything from guitars and trombones to violins and xylophones to kids in 50 states and 35 countries.

We collect and redistribute more than 2,000 instruments annually and, in our 31-year journey, we've become a full-time force for good in the musical community.

Request an Instrument

Hungry for Music collects and distributes instruments including brass, woodwinds, strings, electric keyboards, drums and other percussion, as well as amps and accessories.

Who Hungry for Music Helps

• Music teachers at Title One schools who identify children who cannot participate because of lack of funding.
• Music directors at innovative after-school music programs.
• Social workers who have young clients who would benefit from music therapy.

We only accept requests from public school music teachers, administrators, after-school/summer music program directors, and social workers. 

In our history, we have supported music programs in 40 different countries through stateside sponsors (i.e. business, school, church). We do not accept requests directly from international programs.

Title One School Music Teachers

Our music instrument donation program for Title One public schools is designed to support teachers who have a few students who cannot participate in class because of financial need. We do not outfit entire music programs. 

The NEA Federal Rescue Implementation Network Grant provides up to $100,000 per year for two years to state affiliates for hiring a coordinator to implement the American Rescue Plan in support of public education. This funding is specifically for backfilling a position that must remain filled for at least ninety days, ensuring effective oversight of federal recovery initiatives within the affiliate.

The Indigenous Scholarships: Arts Fund facilitates artistic development for Aboriginal Australian, Torres Strait Islander, Native American, Alaskan Native, and Native Hawaiian artists. Offering up to $5,000, it supports projects in each other's countries, with applications due in March and September. Since 2002, over $1 million has been awarded to more than 500 artists, fostering cultural exchange and growth in the arts between Australia and the USA.

The SAF National Awards Program recognizes exceptional student leaders in forestry. The Student Leadership Award honors an SAF student member demonstrating leadership skills at various levels. Recipients receive a $200 honorarium, complimentary convention registration, and up to $500 for travel expenses. Additionally, the recipient's faculty advisor and SAF Student Chapter benefit from $150 each. This award aims to encourage student engagement and excellence in sustainable forestry and resource management.

Samardzija-Gutesha Family Fund

The Field of Interest Fund reflects the Samardzija-Gutesha family’s values and commitment to giving back. It supports education and hands-on learning in farming, soil health, and water conservation, with a focus on FFA members and associate-level college students.

Scholarships benefit graduating seniors and second-year post-high school students who are originally from DeKalb County high schools with FFA programs.

The Samardzija-Gutesha Family Fund provides scholarships for post-high school students pursuing education in agriculture or conservation, as well as paid internships with local farmers, and conservation professionals. It also supports educational seminars on topics such as sustainable farming and agricultural business, and provides grants to local organizations that align with the donor’s values.

In its first year, the Fund awarded $65,000 in scholarships to eight graduating seniors from DeKalb, Genoa-Kingston, Indian Creek, Somonauk, and Sycamore high schools (pictured above). Each student attending a two-year college received a $5,000 scholarship, while students planning to attend a four-year university received $10,000.

The Carl Alwin Schenck Award, presented by the Society of American Foresters, honors exemplary contributions in forestry education. This prestigious award recognizes individuals with at least ten years of professional experience who demonstrate outstanding teaching abilities and commitment to forestry. Awardees receive a $500 honorarium, complimentary registration for the SAF national convention, and up to $500 for travel expenses. This award underlines the importance of effective education in advancing sustainable forestry practices.

The Bernice Ash Memorial Award honors the legacy of a retail music visionary by providing a $5,000 grant to mid-career professionals employed by NAMM member companies. This award aims to support emerging leaders in the music industry through professional development opportunities and a one-year mentorship with NAMM Young Professionals. Eligible applicants must have at least five years of experience and agree to use the funds for professional training, enhancing their leadership skills and career growth.