Best Large Grants for Nonprofit Organizations in Alabama

About

Central Carolina Community Foundation is a nonprofit organization that helps generous people give back to the Midlands of South Carolina in ways that matter. Since 1984, we’ve been a trusted partner, helping individuals, families, and businesses make smart, meaningful contributions that support local nonprofits, scholarships, and community projects.

Easterby Family Scholarship ($7,000)

This renewable scholarship is for students from Laurens County, South Carolina who are pursuing graduate or post-graduate education in the fields of theology or medicine. 

The Transformative Organizing Grants, funded by the Arch Community Fund, aim to bolster grassroots movements advocating for systemic change. These grants, ranging from $15,000 to $25,000, prioritize organizations with 501(c)(3) status and an annual budget under $1 million. The focus is on empowering community leadership through anti-capitalist solutions, promoting intersectionality, and addressing immediate needs while fostering long-term structural change. Eligible groups are encouraged to apply for support in their transformative organizing efforts.

The Spight Family Foundation Grants aim to enhance the well-being of families and support environmental initiatives that benefit future generations. They welcome charitable organizations that align with their mission, regardless of location, with a primary focus on Northern California. By funding various projects, the foundation seeks to foster community health and sustainability, making a lasting impact on both local and global scales.

The Community Foundation of Western Massachusetts administers over 160 scholarships. Some of the funds help students from a particular school or area; others provide financial assistance to those pursuing a specific field of study; still others assist students that are most in need. Students who apply to the Scholarship program may be eligible for many of these funds.

William T. Maunsell Memorial Scholarship Fund

To support graduating seniors from Westfield High School, Westfield Vocational Technical High School and St. Mary’s High School in Westfield who have average grades and are pursuing degrees in education, criminal justice or nursing.

Additional Guidelines

• Students can receive up to $3,000 in scholarships from the Community Foundation.
• Scholarship awards could impact the financial aid offered by a college, and students are advised to check with their college financial aid offices about this.
• Scholarships may be used to offset tuition, fees, room and board, and other items included as part of the cost for attending the institution. Some part and/or all the award could be considered taxable income. It is advisable students check with the college or tax accountant regarding this matter.

Beekhuis Scholarship

Award:

• One time award of $4,000.

The ACS Congressional Fellowship Program offers trained scientists the chance to engage in the policy-making process, providing critical information to lawmakers on science-related issues. Each year, two fellows are placed in the offices of Senators, Representatives, or Committees, with the aim of educating them on how science policy is formed. Candidates with a strong background in chemical sciences or engineering are encouraged to apply, regardless of whether they hold a doctorate.

The East Texas Estate Planning Council Scholarship, administered by the East Texas Communities Foundation, supports graduating seniors pursuing careers in accounting, law, finance, banking, investments, insurance financial planning, or philanthropic planning. This scholarship reflects a commitment to education and aims to alleviate financial barriers for students in East Texas. Applicants must demonstrate financial need, with FAFSA required, and can attend any college in the United States for one year.

Seattle Foundation is an agent of change, igniting powerful, rewarding philanthropy to make Greater Seattle a stronger, more vibrant community for all.

At Seattle Foundation, we believe that community is more than a place. It’s the shared understanding that our joy and well-being are tied to one another. Every day we work with nonprofits, philanthropists, and partners like you to strengthen community by igniting powerful philanthropy and advancing long-term solutions. Because it takes all of us to create a joyful region where every person can thrive.

Black at Microsoft Scholarship

This scholarship supports high school seniors who self-identify as Black or African American and plan to study in Engineering, Computer Science, Computer Information Systems, Business Administration, Finance, or Marketing at an accredited four-year college or university. This scholarship varies from $2,500 to $5,000 with up to 50 awards granted.

The AMRV RC&D Council Grants provide essential funding to support Alabama communities in enhancing their human and natural resources. These grants are aimed at 501c3 non-profit organizations and government units, focusing on projects that improve local quality of life. Eligible projects must be conducted in specific counties, including Cullman, DeKalb, and Madison. By fostering community growth, the grants play a vital role in promoting sustainable development and well-being across the region.

The U.S. Department of Energy (DOE) is launching the PROSPECT Program to enhance education in critical technologies, targeting an investment of up to $100 million. This initiative aims to develop a skilled workforce across the critical minerals and materials sector, supporting the entire value chain from resource extraction to recycling. By fostering collaboration among academia, industry, and national laboratories, the program seeks to strengthen U.S. economic competitiveness and energy security.

The Historical Transportation Marker Program provides grants to commemorate significant transportation methods used before 1945, such as canals, bridges, railroads, and aircraft. Eligible applicants include 501(c)(3) organizations and government entities in the U.S. Grants aim to recognize historical facts with clear inscriptions, supported by documentation, while ensuring markers are publicly accessible near existing sites. This initiative highlights the evolution of transportation and its impact on community development.

The SC Ministry Foundation provides annual grants aimed at supporting nonprofit organizations aligned with the mission of the Sisters of Charity of Cincinnati. These grants can be used for core programs, planning, and program expansion. Eligible organizations must demonstrate financial sustainability and avoid duplication of services. The application process starts with a pre-application survey, and funding decisions are typically made by June 30. Priority is given to projects in education, healthcare, and social services.

The Choice Neighborhoods Implementation Grants for Fiscal Year 2025 support revitalization efforts in severely distressed public housing and surrounding neighborhoods. This program encourages collaboration among local governments, housing agencies, and community partners to create comprehensive plans aimed at improving housing quality, promoting upward mobility for residents, and attracting long-term investment for neighborhood development. Successful applicants will implement their Transformation Plans, which were developed through prior Planning Grants to enhance the quality of life for residents.

The Indigo Oak Fund, based in Colorado, is dedicated to enhancing education, the arts, and social justice, particularly through its Equal Justice Under the Law Grant Program. This initiative supports organizations that promote fairness in the justice system, rehabilitation, and civic engagement. By funding programs focused on personal empowerment and equal opportunities, the fund aims to foster lifelong learning and improve lives, particularly for women and children in need.

The ASTR Translation Prize recognizes the vital contributions of translators in theater and performance studies. It honors an exceptional English translation of works such as plays, performance texts, scholarly books, and articles published in the last calendar year. The award includes a $500 honorarium and free registration to the annual ASTR conference, promoting the importance of translations in enhancing the global theater landscape.

The Actions of Public Witness Grant, offered by the Unitarian Universalist Funding Program, provides matching grants of up to $1,500 to Unitarian Universalist congregations engaging in timely actions of public witness. This initiative supports efforts in social and environmental justice, encouraging congregations to mobilize during critical moments. Grants are available on a rolling basis and are intended for urgent projects that extend beyond the regular grant timeframe. Notably, individual applications are not accepted.

Scholarships

Since awarding our first $500 scholarship in 1987, the Saginaw Community Foundation has awarded college scholarships to area students totaling more than $13.7 million, thanks to our generous donors. Each year, over 500 college-bound or career and technical education students benefit from our scholarship awards.

Our single application process makes it easy to potentially qualify for one or more of our 260+ scholarships.

JustJane Art Scholarship Fund for Women

Truly unique humans like Jane Marie Ewing do not populate the universe very often, and the JustJane Art Scholarship for Women was created to honor her remarkable spirit.

Jane was an artist at heart, finding joy in countless creative pursuits – whether baking delectable treats, capturing life’s beauty through photography, or expressing her imagination in fashion and digital illustration. Her zest for life was infectious, often bringing laughter through her playful “Jane Pranks”, which will forever live in the hearts of family and friends. Jane shared an inseparable bond with Kyle, each the center of the other’s universe. Tragically, Jane was taken from this world unexpectedly in 2025.

Her vibrant artistic soul touched every aspect of her life – from painting and interior design to crafting costumes for parties and pranks. Though her passion for art wasn’t fully nurtured early on, once she embraced it later in life, creativity flowed freely, illuminating the lives of everyone around her. Jane saw beauty everywhere, and her art became a reflection of that vision.

This scholarship carries forward Jane’s legacy, helping future generations cultivate their own artistic passions. It is a reminder to future generations that art has the power to transform lives.

The Value Assessment and Health Outcomes Research Postdoctoral Fellowship, funded by the PhRMA Foundation, offers a $60,000 stipend annually for up to two years. This fellowship supports researchers, both U.S. and non-U.S. citizens, engaged in innovative studies aimed at evaluating the effectiveness and value of healthcare interventions. Applicants must be within five years of postdoctoral study and hold a relevant doctoral degree. This opportunity fosters collaboration and patient engagement in health outcomes research.

The Focused Technology Research and Development (R01) grant supports innovative projects aimed at developing technologies to enhance biomedical research. This funding opportunity emphasizes the creation of laboratory instruments, algorithms, and biological systems that can significantly improve research capabilities. Key deadlines for applications are set for February, June, and October of 2025 through 2027, ensuring ample time for proposal submissions. The initiative is funded by the National Institutes of Health (NIH), part of the US Department of Health and Human Services.

The Volk – Geyman Scholarship, established by the San Juan Pilots Association, honors John Volk and John Geyman by providing financial assistance to students pursuing careers in aviation and medicine. This scholarship aims to support high school graduates with a commitment to academic excellence and community service. Eligible fields include aviation-related studies and emergency medical training. By fostering leadership and service, the scholarship encourages students to follow the inspiring examples set by its namesakes.

Hendrix-Murphy Foundation

Enhancing literature & language at Hendrix College since 1978.

In homage to Bertie Wilson Murphy’s passion for the study and appreciation of literature and language, the Hendrix-Murphy Foundation at Hendrix College was founded in 1978 with an endowment by her son, Charles H. Murphy, Jr., former CEO of Murphy Oil Corporation. Mrs. Murphy was a 1905 graduate of Galloway Women’s College in Searcy, Ark., which merged with Hendrix College in Conway in the 1930s. Charles H. Murphy, Jr., was a member of the Hendrix Board of Trustees and served as chair. 

The Foundation's programs are overseen by a Board of Directors that is headed by the president of the College and includes Murphy family members, the provost, and representatives from the Hendrix Board of Trustees.

The Hendrix-Murphy Book Award

Hendrix is proud to offer the Hendrix-Murphy Book Award to an outstanding high school junior who demonstrates distinguished scholarship or leadership in literary studies (English, creative writing, foreign languages, or drama).

Hendrix-Murphy Book Award recipients will receive a copy of Poems to Read: A New Favorite Poems Anthology, edited by Robert Pinsky and Maggie Dietz.

Students may be nominated by their English, languages, creative writing, or drama teacher or guidance counselor by using the required form.

The Douglas Dockery Thomas Fellowship in Garden History and Design, established by the Garden Club of America, supports graduate students in studying and researching garden history and design. This annual fellowship promotes the GCA’s commitment to gardening education and conservation. Research topics may include innovative garden restoration techniques and the impact of community gardens. The fellowship aims to nurture talent and address the growing importance of gardens in our environment.

The Value Assessment and Health Outcomes Research Faculty Starter Grant, offered by the PhRMA Foundation, supports emerging researchers at U.S. universities. With a funding of $100,000 for one year, it aims to advance studies on the effectiveness and value of healthcare interventions. The grant promotes innovative research in areas such as clinical outcomes, health equity, and patient engagement, ensuring that diverse perspectives are included in the evaluation of healthcare solutions.

The 2025 Vilcek Foundation Grants aim to support nonprofit organizations that celebrate immigrant contributions to the arts and sciences. The foundation invites applications from organizations operating under U.S. IRS Section 501(c)(3) that promote diversity and inclusivity. Grants will be prioritized for new partners and those in states without prior funding. This initiative underscores the foundation's commitment to fostering appreciation for immigrant communities and their impact on society.

The Bruce J. Heim Foundation Grant supports organizations that empower young individuals with exceptional potential in academics and the arts. Established in 1986, this private foundation aims to provide financial assistance that fosters skill enhancement and personal growth. The Board evaluates grant requests monthly, assessing the viability and significance of each organization’s project. The Foundation's goal is to inspire recipients to realize their potential and contribute to philanthropic efforts, echoing the support they received.

The NeuroNEXT Small Business Innovation program invites small businesses to apply for exploratory clinical trials involving investigational agents, including drugs, biologics, and devices. These trials aim to gather critical data to support the design of future clinical studies, particularly focusing on diseases aligned with the NINDS strategic plan. Applications are due by 5:00 PM local time of the applicant organization, emphasizing the importance of timely submissions.

The Jerome H. & Dr. Elizabeth Emling Post Graduate Fund, established by the Erie Community Foundation, supports Erie County residents pursuing doctorate degrees or advancing master's degrees in Social Service or Education. In 2023, over $800,000 was awarded to more than 500 students for post-secondary education. Priority is given to doctoral candidates already enrolled in relevant fields, ensuring support for those committed to making a difference in their communities.