Best Large Grants for Nonprofit Organizations in Alabama

The Judith A. Ingram Memorial Scholarship Fund, established by The Foundation for Enhancing Communities, honors the legacy of Judy Ingram, a dedicated educator who inspired many in elementary education. This scholarship supports graduating seniors from local school districts planning to major in elementary education, emphasizing academic achievement and financial need. It aims to foster future educators who will continue Judy's commitment to nurturing young minds and enhancing educational opportunities in the community.

The Celia C. Newcomb Memorial Scholarship, managed by the Crown Point Community Foundation, aims to enrich the lives of South Lake County residents. This scholarship supports Lake County, IN residents pursuing degrees in Education, including high school graduates and adult learners. Applicants must provide an additional essay and meet specific eligibility criteria. It embodies the foundation's mission to address community needs through charitable giving.

This funding opportunity aims to advance mechanistic research for precision probiotic therapies. It invites R33 applications focused on characterizing individual differences in probiotic responses, identifying responder subgroups, and enhancing clinical outcomes. The goal is to develop strategies addressing barriers to effective probiotic use, accounting for human variability. Proposals should include innovative studies using animal models or human subjects, supported by preliminary data to test biological patterns and their effects on health outcomes.

The Japanese Teaching Material Purchase Grant, provided by the Japan Foundation, Los Angeles, supports U.S. educational institutions in acquiring resources for Japanese language courses. Grants, not exceeding $1,000, can be used for textbooks, audio-visual aids, and other teaching materials. Eligible applicants include non-profit organizations and Japanese heritage schools. However, the grant does not cover electronics or consumable supplies, and materials purchased become institutional property, not personal.

About

Founded in 1971, the Mensa Foundation was established by members of American Mensa to extend the organization’s impact. While connected by a shared purpose, the Foundation operates independently, guided by its own Board of Trustees, strategic plan, and initiatives.

Grants & Fellowships

Early Career Mini-Grant

The Mensa Foundation empowers emerging researchers through its Early Career Mini-Grant program.

Designed to support post-doctoral researchers and early career faculty, this grant funds innovative studies that advance our understanding of intelligence, creativity, gifted education, and related fields.

Details

The Early Career Mini-Grant provides $2,500 to support post-doctoral researchers and faculty within five years of completing their doctoral degree. This grant is intended to promote groundbreaking studies that advance our understanding of intelligence and its applications in education and beyond.

Grant Components

The ROSES 2025: A.17 Hydrosphere program by NASA aims to enhance our understanding of Earth's water systems, focusing on Ocean Physics, Precipitation Science, and Terrestrial Hydrology. This initiative invites proposals targeting specific priorities within these disciplines to advance knowledge on water distribution and movement across the Earth. Proposals will undergo rigorous peer review to ensure transparency and scientific integrity, aligning with NASA's commitment to reproducible and collaborative research.

The National PTA Outstanding Advocacy Awards recognize exemplary efforts by state, local, and individual PTA advocates dedicated to improving the education, health, and well-being of children. Established by the National PTA, these awards highlight four categories of advocacy: Outstanding State PTA Advocacy, Outstanding Local PTA Advocacy, Shirley Igo Advocate of the Year, and Outstanding Youth Advocate of the Year. Awardees will be celebrated at the National PTA’s Legislative Conference in March 2026.

The Vilcek Foundation's 2026 Prizes for Creative Promise in Fashion & Design and Fashion & Culture will award six $50,000 prizes to young immigrant professionals. This initiative recognizes early- and mid-career creatives in fields such as fashion design, writing, and styling, highlighting the vital contributions of immigrants to the arts in the U.S. Eligible applicants must have at least five years of experience and intend to pursue their careers in the country.

The JAMS Foundation / NAFCM Mini-Grant Program offers funding to support innovative community mediation programs that foster sustainability and growth. This initiative emphasizes conflict resolution training for local leaders, enabling them to effectively address community issues. Through structured peer interactions, grantees share best practices and insights. Resources generated by the program are freely accessible to enhance the wider community mediation field, ensuring shared knowledge and enhanced practices across the nation.

Alliance for Cancer Gene Therapy

Unlike surgery, chemotherapy and radiation, cell and gene therapies harness the power of your immune system to destroy cancer cells without harming healthy tissue. We fund the research that will make this vision a reality.

Collaborating with partners and funding research fellows, we are transforming cancer treatments today while bringing the world closer to a cure for all cancers tomorrow.

ACGT Investigator Award in Cell and Gene Therapy for SOLID TUMOR CANCERS 

Purpose

Alliance for Cancer Gene Therapy, Inc. (ACGT) funds breakthrough research that is transforming cancer treatment through cell and gene therapy. This ACGT grant award is for those conducting translational cell and gene therapy research specifically in solid tumor cancers.

Research Objectives

Cell and gene therapy for solid tumors poses major challenges driven by antigen heterogeneity, physical exclusion, immunosuppressive microenvironments, genomic instability, and safety limitations. This RFA seeks innovative, translational cell and gene therapy strategies that directly address these barriers.

Proposed approaches should demonstrate the capacity to: (1) overcome antigen escape through multi-targeted designs that broaden patient populations and account for heterogeneity and resistance due to antigen loss; (2) enhance trafficking, infiltration, and persistence within solid tumor sites; (3) resist or reprogram the immunosuppressive tumor microenvironment; and (4) incorporate built-in safety and controllability mechanisms suitable for clinical translation. Successful proposals will integrate these elements to enable durable, precise, and scalable therapeutic impact in solid tumors.

Building on the priorities outlined above, this RFP encourages proposals spanning a broad range of cell and gene therapy (CGT) platforms and rational combinations, including but not limited to:

• Engineered T Cell Approaches
• Innate and Alternative Immune Cell Platforms
• Gene Editing & Synthetic Biology Strategies
• Microenvironment-Modulating Strategies
• Combinatorial Approaches

Proposals that integrate multiple strategies to overcome trafficking, suppression, antigen escape, and safety barriers in a coordinated manner are strongly encouraged. Preference will be given to approaches with clear mechanistic rationale and a credible path toward clinical translation in solid tumors.

The Schilling Scholarship, offered by the Community Foundation of the Ozarks, provides six $3,000 scholarships to graduating high school seniors from select schools. Renewable for up to three years, recipients must maintain a 3.0 GPA, enroll in 12 credit hours, and major in Agriculture. An essay submission is required, and applicants must demonstrate financial need by submitting their FAFSA-SAI. This scholarship aims to support students pursuing degrees in various Agriculture fields.

Community Foundation of the Fox River Valley

The Community Foundation of the Fox River Valley is a collection of individual funds and resources given by local citizens to enhance and support the quality of life in the Fox River Valley of Illinois.

We are a tax-exempt public charity that allows individuals, businesses, and non-profit organizations to establish permanent endowments and temporary funds within the confines of one large foundation.

Foundation funds are used to provide grants to non-profit organizations and scholarships to area students. The Foundation also hosts a Youth Engagement in Philanthropy (YEP) program, which helps high school students learn more about philanthropy and empowers them to make a difference in the community.

The Community Foundation of the Fox River Valley serves the City of Aurora, Kane County, and Kendall County within the State of Illinois.

John Masus Memorial Scholarship Fund

Originally the Masus Financial Group Scholarship Fund, the fund was renamed the John Masus Memorial Scholarship Fund as a memorial to John Masus at the time of his passing.

The Fund supports scholarships to graduating high school seniors who reside within the 60510 zip code in Kane County. 

The monetary value of each scholarship award varies depending upon the amount available in each individual scholarship fund. The most common scholarship award amount is $1,000 for a single year. Scholarships are designated as non-renewable one-year awards or renewable multi-year awards depending upon the scholarship fund criteria, as established by the donor of the scholarship fund.

The Damon Runyon Physician-Scientist Training Award aims to address the shortage of physician-scientists by supporting U.S. Specialty Board eligible physicians in cancer research. This award provides funding for up to four years, enabling awardees to dedicate 80% of their time to research while maintaining clinical skills. The program seeks to eliminate financial barriers, allowing talented clinicians to transform into leading researchers capable of advancing cancer treatment and prevention.

The Pittsburgh Foundation provides scholarship opportunities for students to pursue their educational goals. Scholarships are available for graduating high school seniors, undergraduates, graduate, medical and professional school students who are attending community colleges, four–year universities, graduate schools, and career/technical schools.

Lightbown Family Scholarship Fund

The Lightbown Family Scholarship Fund was created at The Pittsburgh Foundation to provide scholarships for students from Allegheny County pursuing a career in education. Corinne Elsie Lightbown passed away peacefully on Jan. 7, 2017 at the age of 86 having lived a full and rewarding life. Connie, as she was known to friends, loved life, people, friends and family as well as traveling and discussing movies, political issues and literature. She was an English teacher for 34 years with the Mt. Lebanon High School and taught in London, England, and Japan. A firm believer in the value of a good education, she established this scholarship fund in her name to support students in their academic studies. She never married so had no children of her own, yet her many students became a part of her extended family through the years. Many remained in touch with her and considered her as a mentor and friend. It was her wish that this scholarship would continue beyond her life in this same spirit.

• Award varies
• Award Type: Single Year. Previous recipients are encouraged to re-apply in consecutive years.

About Boeing

A leading global aerospace company and top U.S. exporter, Boeing develops, manufactures and services commercial airplanes, defense products and space systems for customers in more than 150 countries. Our U.S. and global workforce and supplier base drive innovation, economic opportunity, sustainability and community impact. Boeing is committed to fostering a culture based on our core values of safety, quality and integrity.

The Employees Community Fund (ECF) of The Boeing Company

One of the largest employee-managed funds of its kind in the world, the Employees Community Fund (ECF) of The Boeing Company has empowered employees to make a greater impact by pooling their tax-deductible donations for more than 60 years. Employee-led grantmaking committees at 20 Boeing sites provide combined employee donations to nonprofits in their communities through ECF grants.

Charitable or educational organizations can apply for grants from the Employees Community Fund (ECF) of The Boeing Company.

Puget Sound Chapter

The Employees Community Fund (ECF) of Boeing Puget Sound is a pooled fund consisting of recurring payroll contributions from generous Boeing employees. It funds local nonprofits that help thousands of families and individuals in the Puget Sound region where Boeing employees live and work.

ECF focus areas

ECF makes grants to 501(c)(3) Health & Human Service nonprofits such as food banks, job-training programs, shelters, transitional housing, mental health services, and low-income medical clinics. ECF seeks the direct client benefit of each grant to ensure that our employees’ contributions directly help those in need.

ECF funding criteria

ECF has two distinct grant categories – Supporting Grants and Capital Campaign Grants.

ECF of Boeing Company: Puget Sound Chapter Supporting Grants

Consideration is given to nonprofits/agencies that are performing well and are seeking to upgrade, replace or modify elements of their infrastructure.

• Supporting grants cannot exceed $50,000. The requested amount cannot be more than 10% of an agency’s gross annual revenue.
• Supporting grants will be considered only for agencies benefiting residents in the Puget Sound Region.
• Supporting grants help agencies continue to effectively provide services through enhanced direct client benefit by aiding them in procuring and/or paying for items such as:
  • Equipment (ex. office, kitchen, industrial, furniture, etc.)
  • Vehicles used to support clients and/or transport food and/or goods (cost of vehicle and accommodations, tax, and licensing only; operating expenses, such as insurance, fuel, etc. is not allowed)
  • Phone systems
  • Cell phones for direct client use
  • Remodels and/or renovations (must hold at least a 10-year lease or own the building)
  • Purchase or construction of new buildings
  • Computers or tablets for direct client benefit and/or use
  • Software for direct client benefit and/or use (ex. Augmentative and alternative communication (AAC) device)
  • Information Technology expenses, without which procured tools would not work
  • External improvements for client safety (i.e. security system, exterior lighting, improved ADA accessibility, new or refinished pavement or concrete)
• Supporting grants which are accepted must be spent as approved within nine (9) months.

The Owen Family Foundation Grant supports charitable organizations primarily in East Texas and the Minneapolis/St. Paul area, focusing on health, education, human services, and religious initiatives. Organizations must have a 501(c)(3) status and past funding is required for Twin Cities applicants. The foundation is committed to promoting philanthropy and ensuring access to funding for eligible charities, while maintaining a non-discriminatory policy.

The Detter Family Foundation Education Scholarship, offered by the Grand Haven Area Community Foundation, aims to support residents of Allendale Charter Township pursuing post-secondary education. This competitive scholarship considers various criteria including financial need, academic achievement, and personal goals. Applicants can apply just once to be eligible for all applicable foundation scholarships, ensuring a streamlined process for securing educational funding.

The BJA FY 2026 Students, Teachers, and Officers Preventing (STOP) School Violence Program aims to enhance school safety by funding initiatives that train staff and students, develop threat assessment teams, and implement technology solutions like anonymous reporting systems. This program supports effective strategies to identify and mitigate risks of school violence, ensuring students have the tools necessary to foster a secure learning environment while adhering to the guidelines set forth by the STOP School Violence Act.

The Dorsey & Whitney Foundation Grant supports charitable initiatives in communities where Dorsey attorneys reside. Established in 1982, it focuses on organizations that provide legal services to the disadvantaged and engages attorneys in volunteer roles. Each year, around 200 direct grants are awarded across North America, alongside additional support for numerous other organizations through a matching program. This commitment highlights the foundation's dedication to cultural, civic, educational, and social welfare.

The Community Foundation of Carroll County supports nearly 70 academic, sports, special circumstances, and 4-H scholarships. Search scholarships by name, or sort by application type.

Georgia E Frank Scholarship

The mission of the Georgia E. Frank Scholarship Fund is to support graduating Carroll County high school students of all backgrounds and needs as they pursue their dreams of being a teacher. As Georgia was a life-long Family and Consumer Science teacher in Carroll County, this fund aims to invigorate, encourage, and support aspiring young educators as they transition from high school to the collegiate stages of their training. As a teacher, Georgia encouraged her students to love what they do, to do it well, in order to make the world around them a better place to live. We hope this fund provides assistance to similarly minded young people as they pursue their future teaching career.

The Foist Family Perseverance Scholarship Fund, established by the Berkshire Taconic Community Foundation, aims to support adult learners and graduating high school seniors from Berkshire County pursuing careers in healthcare and sciences. With a focus on clinical and research fields such as nursing and occupational therapy, this fund seeks to empower individuals in their educational and professional journeys, promoting economic mobility and high quality of life in the community.

The FY 2027 DoN HBCU/MI Program aims to enhance the research capabilities of Historically Black Colleges and Universities and Minority Institutions. This initiative promotes innovative solutions to naval science challenges while engaging students and faculty in STEM fields. Key objectives include strengthening research infrastructure and fostering collaborative efforts across institutions. White papers are due by September 18, 2026, and should clearly outline the proposed advancements in naval-relevant science and technology.

Scholarships support aspiring college students who hold the promise of tomorrow’s progress.

Together, our competitive grants and scholarships help our region rise thanks to the vision and generosity of our donors.

Thomas William Bennett Memorial Scholarship Fund

He believed that a person could do anything if they sat down and read how to do it. When WWII started, he was the first man from the state of South Carolina to enlist in the U.S. Army. He quickly rose to captain and spent most of the war in the Pacific (the Queen of Fiji considered him a friend). Later, Thomas had a long career at Harcourt Brace publishing.

The Research on Research Security Program, funded by the National Science Foundation, aims to foster collaboration between STEM researchers and research security practitioners. It encourages interdisciplinary approaches to enhance evidence-based research on security issues. Proposals can include conferences, workshops, and planning grants, as well as international partnerships, to address U.S. concerns in research security. This initiative is vital for developing a robust community in this emerging field.

The Graduate Education Fund offers scholarships for American and Australian graduate students to study in each other's countries. With deadlines in March and September, eligible applicants can receive up to $40,000 to support their education in fields like Science and Technology. This initiative fosters cross-cultural academic collaboration and requires applicants to be enrolled in accredited programs, ensuring a high standard of educational exchange.

Holcomb Family Education Scholarship

This scholarship was established in 2008 by the Hall County Optimist Club to honor long-time educators, J.H. Holcomb and his sisters, Margaret, Mildred, and Nell. Applicants must have demonstrated financial need and have a minimum 3.0 GPA. In 2026, one scholarship award of $1,000 will be offered.

The Northeast Asia Council Japan Studies Grants support American citizens and permanent residents conducting scholarly research on Japan within the U.S. Offering up to $2,500, including daily expenses, these grants aim to enhance the quality of teaching and research in Japanese studies. Eligibility includes being an AAS member and not having received funding in the last three years. Applications are reviewed based on project merit and financial need, prioritizing those with limited access to institutional funding.