Best Large Grants for Nonprofit Organizations in Alabama

The Research Enhancement Award Program (REAP) aims to boost basic and clinical research at health professional and graduate schools that have historically received limited NIH funding. By supporting small-scale research projects led by faculty, REAP fosters student engagement in significant research endeavors, enhancing their educational experience. Eligible institutions must grant advanced degrees in health professions and have received under $6 million in NIH support in four of the last seven years, promoting broader participation in the nation's biomedical research efforts.

The Klingenstein-Simons Fellowship Awards in Neuroscience support early-career investigators conducting basic or clinical research focused on neurological and psychiatric disorders. Awardees receive $150,000 annually for three years, aimed at fostering innovative research that contributes to understanding and treating these disorders. The fellowship encourages applications from underrepresented groups and prioritizes candidates with promising scientific careers who may not have received substantial prior funding, promoting collaboration and mentorship in the neuroscience community.

The American Academy of Otolaryngology–Head and Neck Surgery Foundation is inviting proposals for the CORE Funding: AHNS Presidential Award, aimed at enhancing value-based care in head and neck oncology. This initiative focuses on improving quality, efficiency, and patient outcomes through data-driven strategies. Key proposal components include quality and process measures, along with identifying care gaps. Priority areas include behavioral health integration and innovative contracting models, promoting scalable solutions that enhance care quality and value in this specialty.

The Emergency Educational Grants offer vital financial support of up to $5,000 for undergraduate students who are children of deceased or totally disabled Elks. This grant is renewable for one year and is intended solely for educational purposes, helping cover costs such as tuition and books. Eligible applicants must demonstrate financial need and maintain full-time enrollment in an accredited U.S. college or university, while being unmarried and under 24 years old during the application year.

Community Foundation of the Endless Mountains

Our mission at the Community Foundation of the Endless Mountains is to improve the region’s quality of life through the power of philanthropy. We do this by offering individuals, families, and businesses the most effective charitable giving tools available in the marketplace today. Founded in 1998, the Community Foundation of the Endless Mountains is honored to work with hundreds of donors, nonprofits, advisors, and civic leaders to achieve dreams for making the Endless Mountains region of Northeastern Pennsylvania an even better place to live for everyone.

Scholarships

Many generous individuals, families, and businesses have established scholarship funds to provide support to graduates in our region. Scholarships are available to graduating high school seniors.

Borislav Dumitrov Memorial Scholarship

Established by the family of Mr. Dumitrov to provide tuition assistance for a graduating senior from any of the High Schools in Susquehanna County who will matriculate at a trade school or post-secondary degree program.

The Chevron Changing the Face of Golf Scholarship, awarded by the LPGA Foundation, aims to empower female high school seniors from minority backgrounds pursuing STEM studies. Established in 2022, this scholarship promotes diversity in golf and education, honoring Dinah Shore's legacy. By supporting young women, the LPGA Foundation continues its mission to change the face of golf and provide educational opportunities, enhancing representation in both golf and STEM fields.

The SODEXO Stop Hunger Classroom Challenge invites K-12 classrooms in the U.S. to enhance existing hunger relief initiatives, such as food drives and backpack programs, by making them more impactful and student-driven. This initiative not only addresses the critical issue of child hunger but also empowers students to take action and lead projects that foster community engagement and social responsibility.

The NICHD Resource Program Grants in Bioinformatics aim to support the operation and enhancement of vital bioinformatics databases for research on animal models of embryonic development. These grants promote user training, data curation, and interoperability with NIH resources, ensuring wide dissemination of critical tools and resources to the research community. Applications are due by 5:00 PM local time, with optional Letters of Intent encouraged 30 days prior to the proposal deadline.

The BRAIN Initiative's funding opportunity aims to support the establishment of facilities at minority-serving and IDeA-eligible institutions for the production and distribution of brain cell type-specific reagents. These reagents will enhance neuroscience research by enabling precise manipulation and access to brain cell types, facilitating advancements in understanding circuit functions in various species. The initiative encourages collaboration among awardees to optimize the use of these essential resources across the neuroscience community.

The Seeding Critical Advances for Leading Energy Technologies (Scaleup) Ready initiative by ARPA-E invites applications for funding to advance transformative energy technologies. This program supports innovative projects that demonstrate potential for significant market disruption and emphasizes rigorous project management and technology risk mitigation. Eligible organizations must have inventions conceived during an ARPA-E award, reported in the iEdison system, and hold relevant U.S. patent applications. For further details, visit ARPA-E's website.

EverGreen Dreams

“Empowering young Black women to achieve educational excellence and unlock their limitless potential.”

Today, EverGreen Dreams is a community rooted in hope, equity, and empowerment. Our work centers on providing the resources, mentorship, and opportunities Black women need to thrive. We believe education is more than a pathway to success—it’s a tool for liberation and a foundation for transformation. By investing in the education and development of Black women, we’re dismantling systemic barriers and planting seeds of possibility that will grow for generations.

Building Opportunities for Sistas to Shine (B.O.S.S.) Scholarship

Introduction

Black women navigate systemic barriers in education and the workplace every day. EverGreen Dreams exists to change that narrative. As an organization founded by a Black woman and championed by advocates deeply rooted in our communities, we're committed to creating pathways to success for the next generation of Black female scholars. Through the Building Opportunities for Sistas to Shine (B.O.S.S.) Scholarship, we provide financial support to two graduating high school seniors, awarding each at least $1,000 to help them pursue their educational dreams with one less obstacle in their way.

Description

The Building Opportunities for Sistas to Shine Scholarship (B.O.S.S.) aims to make racial equality a reality by helping outstanding Black cis or transgendered women high school students achieve their dreams to continue their education. 

The scholarships we award vary each year based on the unique criteria of each scholarship. In 2025, we awarded over $3 million in scholarships to over 500 students, including $1.3 million to 110 students in western NC through our Disaster Relief and Resilience Scholarship.

Depending on the scholarship, it may pay for tuition, room and board, books, fees and/or other related educational expenses. 

Fred M. Parrish, Jr. Scholarship Endowment Fund

Graduating high school seniors from public high schools in Johnston County who are continuing their studies at an accredited college, university, community college or technical school. The Scholarship committee shall have the power to make recommendations to the Foundation as to deserving individual recipients and appropriate scholarship amounts, based on academic performance and on financial need.

This will be outlined in your award notification. The minimum scholarship award amount is $1,000.

NCCF scholarship awards are only issued to not-for-profit institutions and government entities such as public colleges or universities.

The Warren MacKenzie Advancement Award supports students and emerging ceramic artists in the U.S. to enhance their skills and knowledge through research and education for up to twelve months. Eligible applicants include current students and recent graduates in ceramics. The award offers a maximum of $2,000 for travel, education, or research, enabling recipients to explore new techniques, collaborate with mentors, and attend workshops, thereby fostering professional growth in the field of ceramics.

The LPGA Foundation

The LPGA Foundation supports women and young people through programs and initiatives aimed at empowering them through the game of golf. Since its founding, The LPGA Foundation has touched more than 500,000 lives through various scholarship and financial assistance programs, along with its flagship junior golf program, LPGA*USGA Girls Golf. The LPGA Foundation was established in 1991 and is a non-profit 501(c)(3) charitable organization, which supports junior golf programs, scholarships, and financial assistance programs for women and young ladies.

Dolores Hope Financial Assistance Initiative

The LPGA Foundation has a tradition of taking care of its members and others in the golf industry. The Financial Assistance Fund was renamed the Dolores Hope LPGA Financial Assistance Initiative in 2007 to acknowledge Hope’s generous support of the fund and her long-time friendship with the LPGA.

Since 2002, the ACA has partnered with L.L. Bean to sponsor the Club Fostered Stewardship (CFS) Program. The CFS Program provides funding to local and regional paddling clubs and organizations that undertake stewardship projects on waterways in their area. The purpose of the program is to encourage paddling clubs to take an active role in protecting and improving the nation's waterways. 

Many of the stewardship needs of our nation's waters are best addressed at the local and regional level. Paddling clubs and watershed organizations are in an ideal position to lead these efforts. These paddlers are often willing to volunteer their time and assist with local stewardship projects. However, clubs often lack the funds needed to pay project expenses. As a result, they miss an opportunity to leverage dozens and sometimes hundreds of volunteer hours that could improve conditions on their favorite waterway.

CFS Grant Program

That is why L.L. Bean and the ACA have teamed up to sponsor the CFS Program.

CFS grants are available for projects that utilize volunteers in efforts to protect, maintain or restore recreational waterways, to provide for or improve public access, or to enhance safe navigation. 

Grant amounts range from $100-$1,000.

Past projects receiving CFS grants include:

• Removing heavy debris and trash from rivers and bays in numerous locations throughout the U.S.
• Improving access for local paddlers
• Establishing water trails 
• Water quality monitoring 
• Environmentally-sensitive woody debris removal 
• Riparian buffer restoration and improvement 
• Environmental education and outreach programs

ACA also offers additional assistance to clubs and organizations for waterway stewardship projects. Clubs and organizations concerned about liability for injuries that occur during stewardship projects may be able to obtain liability insurance coverage through the ACA. Clubs may request additional assistance using the It is not mandatory to be a paddling club to apply. In the past, grants have been awarded to conservation organizations and watershed groups.

Want to learn more about projects that have been funded through the CFS program? Review reports from past years!

The USF Community Impact Grant, established by USA Swimming and the USA Swimming Foundation, aims to enhance competitive opportunities in swimming clubs. Grants of up to $5,000 are available for registered USA Swimming clubs committed to fostering community engagement and collaboration. Eligible clubs can renew their grant for up to three years, promoting diverse access to swimming programs. This initiative particularly supports clubs that partner with educational or public entities and those led by women or minorities.

The Adult Learn-to-Swim Grants, offered by the USA Swimming Foundation in collaboration with U.S. Masters Swimming, aim to enhance swimming safety for adults aged 18 and over. This initiative provides funding to programs that promote swim education, targeting underserved communities. Grants can be used for expenses like pool rentals and scholarships, with a maximum award of $5,000. The goal is to reduce drowning risks and encourage ongoing participation in swimming activities.

The Japanese-Language Learners Event Grant, offered by the Japan Foundation, Los Angeles, provides financial support of up to $1,000 for events that promote Japanese language education across various educational levels. This grant aims to motivate learners through contests and presentations, encouraging participation from multiple schools in the region. Eligible expenses include judge fees, venue costs, and production materials, while closed events for single schools are not supported.

The NIDCR Dentist Scientist Career Transition Award (K22) supports dentists transitioning from NIH postdoctoral roles to tenure-track faculty positions. It provides two years of mentored research training in the NIH Intramural Research Program, followed by three years of independent research funding at an extramural institution. Key deadlines for grant applications include February 12, 2025, and subsequent dates in June and October 2025, with additional deadlines for renewal and AIDS-related applications.

The Environmental Health Sciences Core Centers Program (P30) invites grant applications to support innovative research in environmental health. These centers serve as critical hubs for advancing the goals of the 2025-2029 NIEHS Strategic Plan, providing essential infrastructure and resources for collaborative research. By fostering community engagement and translational research, the program aims to enhance understanding of the connections between environmental factors, human biology, and disease, ultimately improving public health outcomes.

The Brooks and Joan Fortune Family Foundation Grant supports educational, artistic, and outreach initiatives. Applications are accepted year-round, with a focus on projects that yield specific outcomes rather than general operating expenses. While historically centered in Indiana and Florida, the foundation welcomes proposals from across the country. Eligible organizations must hold a 501(c)(3) designation. This grant is an excellent opportunity for nonprofits aiming to make a tangible impact in their communities.

The Land and Water Conservation Fund's Outdoor Recreation Legacy Partnership Program aims to enhance recreational opportunities in underserved communities through significant funding. Offering matching grants up to 50%, with awards ranging from $300,000 to $15,000,000, this program encourages applicants to connect with the Connecticut Department of Energy and Environmental Protection early in the application process for guidance. This initiative supports large-scale projects that improve access to recreational facilities.

The AHA Predoctoral Fellowship aims to enhance research and clinical training for pre-doctoral students pursuing careers in cardiovascular health. Applicants must be enrolled in a relevant doctoral program and demonstrate collaboration with a mentor. The fellowship provides an annual stipend of $28,224, plus health insurance support and project funding. Eligible candidates are full-time students who have completed initial coursework and can commit to research efforts. This opportunity fosters the development of independent researchers in the field.

The NCI Pathway to Independence Award (K99/R00) supports talented postdoctoral researchers in transitioning to independent faculty positions. This program provides essential NCI research funding to facilitate the development of competitive, independent research careers. Applications are due by 5:00 PM local time of the applicant's organization, emphasizing the importance of timely submissions for prospective awardees.

The Academic Research Enhancement Award (AREA) supports small-scale research at institutions that receive limited NIH funding, emphasizing biomedical research for undergraduate students. This program aims to enhance the research environment and provide valuable experiences for students. Eligible institutions must award baccalaureate science degrees and have received no more than $6 million in NIH support over four of the last seven years. This funding opportunity encourages investigator-initiated minimal risk clinical trials to advance NIH missions.

Earl Haas Scholarship

The Earl Haas Scholarship was established through a bequest from the estate of Earl Haas. The purpose of the fund is to provide financial assistance for Kalamazoo County residents or persons who have graduated from a school within Kalamazoo County.

KZCF scholarships may be applied to any items under your school’s cost of attendance (COA). Each school has a different COA that may include items such as tuition, fees, housing, transportation, food, health insurance, etc. Scholarship payments are sent directly to your institution. 

This scholarship is a one-time award, meaning that it will not repeat in subsequent years. The money awarded can be applied to your education costs alongside other scholarships or funding that you may receive, and there are no necessary steps once funds are sent.

Jean Hunse Scholarship

Jean Hunse became a certified public accountant in 1943, started and later served as president of the American Association of Women CPA's, and opened her own accounting firm in Kalamazoo in 1977. This scholarship was established in her honor and provides financial assistance to students studying business at Western Michigan University.

KZCF scholarships may be applied to any items under your school’s cost of attendance (COA). Each school has a different COA that may include items such as tuition, fees, housing, transportation, food, health insurance, etc. Scholarship payments are sent directly to your institution. 

This scholarship is a one-time award, meaning that it will not repeat in subsequent years. The money awarded can be applied to your education costs alongside other scholarships or funding that you may receive, and there are no necessary steps once funds are sent.