Best Large Grants for Nonprofit Organizations in Alabama

The LEGO Foundation Fellowship

Advancing the science and practice of supporting children to thrive

The LEGO Foundation Fellowship is a global initiative supporting researchers working to deepen our understanding of how children thrive. Spanning disciplines from education and psychology to public health, data science, and humanitarian studies, the fellowship brings together early- and mid-career scholars whose work has the potential to generate evidence that matters for children’s lives.

Fellows receive three years of flexible support to pursue rigorous, practically relevant research, and join a cohort of peers working across the fellowship’s themes. In addition to funding research, the program fosters a community of scholars engaged in meaningful exchange with one another and with research, policy, and practice audiences.

The LEGO Foundation Fellowship is developed in partnership with the LEGO Foundation, and administered by SSRC as part of its commitment to supporting scholars whose work bridges research and real-world impact.

Research themes

The LEGO Foundation Fellowship welcomes research proposals that advance understanding of children’s thriving through one of the following three themes: the youngest children in crisis and conflict settings; inclusion and wellbeing of neurodivergent children; and children’s learning and development in an AI-enabled world. Applicants may explore the role of play where it is relevant to the research question. The consideration of play is optional and not a condition of eligibility.

About

Created by the community for the good of the community, the GLCCF is here to turn problems into opportunities through strategic grant making and initiatives created to address our region’s most pressing needs. We work with you to identify your charitable goals, and we ensure that they are carried out efficiently.

Work with us to make the kind of impact you want to see in your community. Let us take on the financial complexities and paperwork, while you focus on the important things like fostering good works throughout our community.

When you give to the Greater Lake City Community Foundation, you are making an investment that will benefit the community, now and in the future.

GLLCF Nursing Scholarship

To award annually a scholarship to a qualified applicant who intends to further his/her education toward a degree in nursing.

The Periodic Paralysis Grant, offered by the Patient Advocate Foundation, assists individuals diagnosed with periodic paralysis in managing out-of-pocket healthcare costs. Eligible applicants must be in treatment or planning to begin treatment for this rare muscle disease. The fund covers various expenses, including medication copays and insurance premiums, ensuring that patients can afford essential care. With a mission to empower and support patients, this grant plays a crucial role in navigating healthcare challenges.

About Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Who we are and our impact

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Paroxysmal Nocturnal Hemoglobinuria (PNH)

Help with healthcare costs for Paroxysmal Nocturnal Hemoglobinuria (PNH)

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

About the disease

Paroxysmal Nocturnal Hemoglobinuria (PNH), also known as Marchiafava– Micheli syndrome, is a rare disease that is characterized by impaired bone marrow function and destruction of red blood cells. PNH is a rare disease that affects the circulatory system.

The Newton E. & Hester G. Dilgard Memorial Scholarship, administered by the Ashland County Community Foundation, supports graduating seniors from Ashland County high schools with a minimum GPA of 2.75. This scholarship honors the legacy of Newton E. Dilgard, a self-made business leader and advocate for education, promoting the pursuit of excellence in chosen fields. It aims to assist students in attending accredited colleges or universities, reinforcing the foundation's commitment to community development.

The William F. Mann Scholarship, established in 2018, supports Albuquerque High School students pursuing full-time college education. It aims to assist students in achieving their educational goals while encouraging community service and good citizenship. Scholarships of up to $2,000 are awarded annually, with recipients expected to maintain a minimum GPA of 3.0 for renewal eligibility. Preference is given to those with a strong community service background, fostering mentorship among peers for future success.

The Judith Halama Ebert Scholarship aims to support graduating seniors from Ashland County high schools with a GPA of 3.0 or higher, pursuing Education, particularly in Special Education. Established by Judy Ebert, a passionate advocate for education, the scholarship reflects her commitment to assist students demonstrating leadership and community engagement. This initiative not only honors Judy's educational legacy but also fosters future educators who will positively impact the community.

The Jennie K. Scaife Charitable Foundation Grant focuses on enhancing family support, women's and children's health, and animal welfare. It aims to fund programs that promote beneficial human-animal interactions and early intervention in addiction prevention. Eligible organizations must have a valid 501(c)(3) designation. Grants align with at least one of the foundation's focus areas, ensuring impactful contributions to community welfare and well-being.

The Retail Merchants Association of Tyler Scholarship, administered by the East Texas Communities Foundation, supports graduating seniors planning to major in Business. Eligible students must be from specific Smith County high schools and demonstrate financial need through FASFA. This scholarship, amounting to $1,000, can be used for tuition, fees, and educational supplies. The unique application process matches students with scholarships, ensuring they apply only once and receive consideration for multiple opportunities.

The Les Paul Foundation Grant supports innovative music education and medical research related to hearing loss. Eligible organizations must be U.S.-based public charities under 501(c)(3) and avoid religious, political, labor, or business affiliations. The foundation prioritizes projects that enhance music production, performance, and STEM/STEAM initiatives, particularly those benefiting individuals in challenging situations. Proposals must detail how they will share Les Paul's legacy in their work.

The Brady Education Foundation offers grants aimed at enhancing educational outcomes for children, particularly in low-income areas. Through collaborations among researchers and educators, the foundation funds Research Projects and Program Evaluations that adhere to strength-based approaches. Eligible organizations include non-profits and academic institutions, with a focus on projects that evaluate effective educational strategies. The foundation emphasizes the importance of measurable outcomes and the potential to inform future educational practices and policies.

The Greenpoint Foundation Grant aims to enhance community life by supporting organizations that focus on agriculture, food security, education, and community enhancement. Established in 2022, the Foundation accepts grant applications year-round for both general operating budgets and specific projects. Priority is given to 501(c)(3) organizations and local government entities, while faith-based programs are considered on a case-by-case basis. Grant recipients must submit impact reports to ensure continued support.

The PERF: CNS Bridge Grant Program aims to support emerging child neurology researchers by providing essential bridge funding while they seek independent research grants from NIH or CIHR. Established by the Pediatric Epilepsy Research Foundation in collaboration with the Child Neurology Society, this initiative seeks to retain talented investigators in the field of pediatric neurology. Since its inception, the foundation has awarded over $18 million to advance pediatric epilepsy research and related conditions.

LSW Architects Legacy Scholarship

The LSW Architects Legacy Scholarship Fund was established in honor of LSW Architects' founding leaders and their ability to imagine and build in creative space. 

Number and Size of Awards:

The number and size of awards may vary and are determined by the selection committee. Minimum award amount is $2,500.

Number of Awards: 4

Total Amount Awarded: $10,000

The National Breastfeeding Support Initiative aims to enhance maternity care quality by engaging diverse partners and providing training to healthcare organizations. It focuses on implementing evidence-based practices to support breastfeeding, ensuring safe and effective maternity care in hospitals across the U.S. and territories. By fostering collaboration and utilizing data for quality improvement, the initiative seeks to create a sustainable impact on maternal and infant health.

The Joette P. Delia Curiano Scholarship is designed for graduating high school seniors from specific schools in the Greater Capital Region who plan to pursue a degree in health care or nursing. Applicants must demonstrate both academic excellence and financial need. This scholarship is part of a universal application process, allowing students to apply for multiple scholarships with one form, thereby increasing accessibility to educational funding.

Herold and Retta Reuss Public Safety Scholarship

Applicants must demonstrate the drive and ability to be successful in pursuing a college education and/or a certification process in the fields aforementioned. Financial information is requested, but not necessarily a determining factor. Students who receive this scholarship may apply for further support in subsequent years.

The Graham Foundation for Advanced Studies in the Fine Arts offers grants to organizations focused on architecture and its role in society. Established in 1956, the Foundation promotes innovative projects that encourage public dialogue, raise awareness, and foster experimentation in the field. Grants, not exceeding $30,000, support diverse practitioners and initiatives, enhancing discourse in architecture, design, visual arts, and related fields. The Foundation encourages projects that demonstrate originality, feasibility, and potential for meaningful impact.

The National Parks Business Plan Internship aims to enhance the operational health of national parks through a graduate-level program that trains students in business management and NPS operations. Participants will engage in substantive analysis, gain insights into park management, and promote federal careers in conservation. This initiative seeks to involve underrepresented graduate students from disciplines such as business administration and public policy, fostering a commitment to stewardship of public lands.

The Child Neurology Foundation offers a Summer Scholarship for first, second, or third-year medical students interested in neurodevelopmental disabilities or child neurology. This scholarship provides $3,500 for clinical research focused on neurodevelopmental disabilities in children or young adults, conducted under the supervision of a qualified subspecialist. Applications are evaluated based on their importance, originality, and contribution to the medical student's development.

The Stranahan Foundation’s Early Childhood Education grant program aims to enhance access to high-quality early education for low-income children. Funding up to $1.5 million is available for innovative proposals that improve professional development for early educators. Key priorities include scalable coaching models, leadership development for under-resourced communities, and community-wide substitute teacher pools. This initiative is designed to tackle significant gaps identified in early childhood education and support effective learning environments.

The Dashanna K. McNeil Memorial Scholarship honors the legacy of a dedicated nursing professional who inspired many through her passion for healthcare. This scholarship encourages aspiring nurses at various educational levels to pursue their dreams in nursing. It supports individuals planning to attend accredited nursing institutions, fostering a new generation of compassionate caregivers, just as Dashanna did throughout her impactful career.

The Dr. Gary King Sharp Memorial Scholarship, offered by the Central Kentucky Community Foundation, aims to support students with a cumulative GPA of 2.5 or higher. Priority is given to those connected with Hospice services or in the foster care system, and to first-generation college students. This scholarship serves as a vital resource to empower students in their educational pursuits and enhance community life.

The DHQP Global NOFO aims to enhance the CDC's mission against antimicrobial resistance (AR) by integrating non-research implementation with focused research. This initiative addresses urgent global threats posed by various pathogens and healthcare-associated infections (HAIs). By leveraging existing CDC networks, the NOFO seeks to improve detection, surveillance, and infection control measures, ultimately reducing illness and mortality while protecting healthcare workers and patients, especially in low and middle-income countries.

Mission

To empower worthy nonprofits by providing critically needed, unrestricted funding that helps them fulfill their missions with confidence and sustainability.

How We Serve Nonprofits

AmFund partners with nearly 800 organizations annually—supporting causes related to health, education, the arts, human services, animal welfare, and more. We’re known for our:

• Signature silent and live auctions featuring once-in-a-lifetime travel experiences.
• National reach with personalized service at events in all 50 states.
• Comprehensive marketing toolkits, onsite staff support, and beautifully displayed materials
• No-cost platform development for virtual and hybrid fundraising
• In-house travel specialists who provide custom planning, extensions, insurance, and 24/7 emergency support.
• Ongoing educational resources, grants, and consulting support for nonprofit development.

Request Support

Our model is built on relationship, trust, and results. Every trip sold, every service provided, and every donor interaction is designed to maximize your fundraising impact—without adding burden to your team.

Who We Are

Buiding a stronger, More Vibrant Community

For over 70 years, the Scranton Area Community Foundation has served Northeastern Pennsylvania as a steward of charitable resources, a grantmaker, and a catalyst for positive change. Guided by our core values of collaboration, trust, integrity, innovation, and inclusivity, we work to ensure that our communities thrive with opportunities for all.

This scholarship is awarded to a student who is matriculating in a performing arts program, has demonstrated commitment to their art, and has demonstrated evidence of community involvement and service to others.

About Scholarships

Through the incredible generosity of our donors, the Community Foundation of South Puget Sound manages 26 scholarship funds that offer a wide range of scholarship awards and encourage students of all backgrounds and educational interests to apply. We also want to extend a sincere thank you to our many scholarship donors, advisors, and scholarship committee members for their investment in our student's bright futures this year and for many years to come!

Learning Seed Foundation Scholarship

The Learning Seed Foundation Scholarship Fund was established by the Learning Seed Foundation to assist graduating high school seniors in Thurston and Pierce counties in obtaining a higher education. This scholarship is designed to benefit primarily students of color who have overcome significant obstacles and demonstrate a commitment to others. The scholarship has the potential to be renewed for up to an additional 3 years of undergraduate education. Reapplication each year is required.