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Best Operating Grants for Nonprofits in Alabama

Find the perfect Operating grants for nonprofits in Alabama on Instrumentl. 9,000+ Operating grants for nonprofits in Alabama in the United States.

9,000+

Available grants

$2.61B

Total funding

$5K

Median grant

9,000+ grants
$2.61B total
$5K median

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9,324 Results based on applied filters

Identifying the Effects of GLP-1 Medications Among Individuals with Cardiovascular, Kidney and Metabolic Disease

American Heart Association
Association/Society
United States
Up to US $300,000
The American Heart Association is inviting proposals for research on the effects of GLP-1 and GIP agonists in individuals with cardiovascular, kidney, and metabolic diseases. This initiative aims to explore how these medications can alleviate the CKM burden. Researchers with expertise in causal inference, machine learning, and cardiovascular research are encouraged to apply, particularly those working in multidisciplinary teams and leveraging various data sources.
Cardiovascular Diseases & Systems Endocrine & Metabolic Diseases Kidney Diseases

Juliette P. Doster Scholarship Fund

Community Foundation of Northeast Alabama
Private
United States
Unspecified amount
The Juliette P. Doster Scholarship Fund honors the legacy of Mrs. Doster, who dedicated forty years to improving healthcare in Calhoun County. This renewable scholarship supports students pursuing associate's or bachelor's degrees, as well as approved workforce training programs. Awarded yearly for up to four years, recipients must maintain academic standards. Funding varies based on the Community Foundation's annual income, and the award covers tuition, housing, supplies, and other educational expenses.
Workforce Preparation & Job Readiness Academic Scholarship Programs Adult Education +2 more

Navigator Emergency Department Diversion Models for Non-Urgent Mental Health Concerns (R34 Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $450,000
This NOFO aims to enhance research on the effectiveness and implementation of family navigation models that divert non-urgent mental health concerns from emergency departments. It will focus on tools for triaging mental health acuity, engaging families with necessary services, and addressing barriers to help-seeking. Important deadlines for grant applications range from February 2025 to October 2027, with optional Letters of Intent encouraged thirty days prior to each due date.
Mental Health & Psychiatric Diseases Children’s Mental Health Emergency Medical Care & Services

Music Therapy Grants

Music Movement
Association/Society
United States
US $1,500 - US $2,500
Music Movement offers grants for music therapy aimed at children and young adults with Autism Spectrum Disorder (ASD) and other developmental challenges. Grants typically range from $1,500 to $2,500, providing financial relief to families seeking therapeutic resources. Eligible applicants include legal guardians of children in the U.S. who select qualified therapists. The organization focuses on enhancing communication, social skills, and emotional well-being through music, benefiting diverse communities and promoting personal growth.
Autism Children With Disabilities Music Education

Comprehensive Suicide Prevention Program for States (363329)

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
US $650,000 - US $1,200,000
The CDC's Comprehensive Suicide Prevention Program for States aims to enhance public health approaches to suicide prevention across the U.S. By targeting high-risk groups, such as veterans and rural populations, the program utilizes data to identify prevention areas, assess existing programs, and implement evidence-based strategies. Key outcomes include improved partner engagement and a measurable reduction in suicide rates. This initiative allows potential applicants to prepare by reviewing relevant data and forming strategic partnerships ahead of future opportunities.
Suicide Prevention

NIAMS Clinical Trial Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $250,000
The NIAMS Clinical Trial Implementation Cooperative Agreement (UG3/UH3) invites applications for the execution of investigator-initiated, interventional clinical trials across various phases. This program supports researchers in finalizing preparations necessary for trial initiation, including IRB establishment and staffing. Successful UG3 projects may transition to the UH3 phase, emphasizing the need for hypothesis-driven studies with significant clinical impact within NIAMS's research mission.
Skin Diseases & Dermatology Arthritis Musculoskeletal Diseases

Direct-to-Consumer Distribution of HIV and other STI Self-Tests

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This funding opportunity aims to enhance a web-based ordering portal for distributing 1.5 million HIV and STI self-tests to high-burden communities. By optimizing access to these self-tests, the initiative seeks to raise awareness, prevent new infections, and improve the health outcomes of users, thereby contributing to better overall public health and wellbeing.
HIV / AIDS

Innovations in Low-Cost and Simplified Pathogen Sequencing Workflows (Tier 3: Advanced Development and Validation Awards)

Gates Foundation
Private
Countries
Up to US $800,000

Innovations in Low-Cost and Simplified Pathogen Sequencing Workflows

Catalyzing Innovation through Partnerships

At its core, Grand Challenges catalyzes bold innovation through partnership - bringing together funders, researchers, implementers, and public health leaders to solve complex global challenges. This multi-partner initiative reflects the Grand Challenges ethos, leveraging complementary expertise and investments to accelerate accessible genomic sequencing solutions for low- and middle-income Countries.

About this Challenge

This Grand Challenge is co-funded by the Gates Foundation, and the Temasek Foundation, and will be managed by the United Nations Foundation. This Grand Challenge is implemented in collaboration with a network of global and regional partners, including International Pathogen Surveillance Network (IPSN), hosted by the WHO Hub for Pandemic and Epidemic Intelligence, the Africa Pathogen Genomics Initiative (Africa PGI), and the Asia Pathogen Genomics Initiative (Asia PGI) as regional technical and public-health partners. This RFP aims to accelerate the development of affordable, scalable, and operationally simple sequencing solutions, enabling routine use of genomics for public health in low- and middle-income countries (LMICs).

Award Structure and Funding Level

To accommodate different stages of innovation maturity, this RFP supports a tiered award structure, with funding levels and expectations aligned to the readiness and scope of the proposed work. Indicative award categories are:

For more mature concepts aimed at workflow refinement, performance optimization, and generation of proof-of-concept and validation data in relevant public-health use cases in LMICs.

Epidemiology & Public Health Molecular Biology Non-Medical Bioinformatics +3 more

Innovations in Low-Cost and Simplified Pathogen Sequencing Workflows (Tier 1: Early Stage Feasibility Award)

Gates Foundation
Private
Countries
Up to US $300,000

Innovations in Low-Cost and Simplified Pathogen Sequencing Workflows

Catalyzing Innovation through Partnerships

At its core, Grand Challenges catalyzes bold innovation through partnership - bringing together funders, researchers, implementers, and public health leaders to solve complex global challenges. This multi-partner initiative reflects the Grand Challenges ethos, leveraging complementary expertise and investments to accelerate accessible genomic sequencing solutions for low- and middle-income Countries.

About this Challenge

This Grand Challenge is co-funded by the Gates Foundation, and the Temasek Foundation, and will be managed by the United Nations Foundation. This Grand Challenge is implemented in collaboration with a network of global and regional partners, including International Pathogen Surveillance Network (IPSN), hosted by the WHO Hub for Pandemic and Epidemic Intelligence, the Africa Pathogen Genomics Initiative (Africa PGI), and the Asia Pathogen Genomics Initiative (Asia PGI) as regional technical and public-health partners. This RFP aims to accelerate the development of affordable, scalable, and operationally simple sequencing solutions, enabling routine use of genomics for public health in low- and middle-income countries (LMICs).

Award Structure and Funding Level

To accommodate different stages of innovation maturity, this RFP supports a tiered award structure, with funding levels and expectations aligned to the readiness and scope of the proposed work. Indicative award categories are:

For technically ambitious or higher-risk, earlier-stage concepts focused on feasibility testing, assay or workflow prototyping, and initial cost-reduction validation. Intended approaches that require focused development to demonstrate viability.

Epidemiology & Public Health Molecular Biology Non-Medical Bioinformatics +3 more

Innovations in Low-Cost and Simplified Pathogen Sequencing Workflows (Tier 2: Mid-stage Development Awards)

Gates Foundation
Private
Countries
Up to US $600,000

Innovations in Low-Cost and Simplified Pathogen Sequencing Workflows

Catalyzing Innovation through Partnerships

At its core, Grand Challenges catalyzes bold innovation through partnership - bringing together funders, researchers, implementers, and public health leaders to solve complex global challenges. This multi-partner initiative reflects the Grand Challenges ethos, leveraging complementary expertise and investments to accelerate accessible genomic sequencing solutions for low- and middle-income Countries.

About this Challenge

This Grand Challenge is co-funded by the Gates Foundation, and the Temasek Foundation, and will be managed by the United Nations Foundation. This Grand Challenge is implemented in collaboration with a network of global and regional partners, including International Pathogen Surveillance Network (IPSN), hosted by the WHO Hub for Pandemic and Epidemic Intelligence, the Africa Pathogen Genomics Initiative (Africa PGI), and the Asia Pathogen Genomics Initiative (Asia PGI) as regional technical and public-health partners. This RFP aims to accelerate the development of affordable, scalable, and operationally simple sequencing solutions, enabling routine use of genomics for public health in low- and middle-income countries (LMICs).

Award Structure and Funding Level

To accommodate different stages of innovation maturity, this RFP supports a tiered award structure, with funding levels and expectations aligned to the readiness and scope of the proposed work. Indicative award categories are:

For concepts with preliminary feasibility evidence that are ready to advance from prototype toward an integrated workflow—optimizing performance, broadening assay or pathogen coverage, and generating more robust cost-reduction and performance data.

Epidemiology & Public Health Molecular Biology Non-Medical Bioinformatics +3 more

LabCorp Charitable Foundation Grants

Labcorp Charitable Foundation
Private
United States
Unspecified amount
The Labcorp Charitable Foundation, a private 501(c)(3) entity, aims to enhance healthcare access and education for all. With grant opportunities focusing on food programs, healthcare services for underserved populations, and STEM initiatives, it seeks to support community health and well-being. Organizations eligible for funding must be U.S.-based and hold tax-exempt status. Requests are reviewed biannually, in March and September, to foster impactful community projects.
Education Community Services Health & Medicine +5 more

The Slomo and Cindy Silvian Foundation Grant

Slomo And Cindy Silvian Foundation Inc
Private
United States
Unspecified amount
The Slomo and Cindy Silvian Foundation Grant supports a range of subjects including education, children's welfare, medical care, medical research, and Jewish philanthropic endeavors. Established in honor of Cindy Silvian, the foundation has awarded over $30 million since 2008. Applications are by invitation only, and organizations must meet specific eligibility criteria to be considered for funding. This year, the foundation allocated over $2.4 million to more than 110 organizations, highlighting its commitment to impactful philanthropy.
Education Health & Medicine Child Welfare Services +5 more

Microsoft Disability Scholarship

Seattle Foundation
Private
United States
US $5,000

Seattle Foundation is an agent of change, igniting powerful, rewarding philanthropy to make Greater Seattle a stronger, more vibrant community for all.

At Seattle Foundation, we believe that community is more than a place. It’s the shared understanding that our joy and well-being are tied to one another. Every day we work with nonprofits, philanthropists, and partners like you to strengthen community by igniting powerful philanthropy and advancing long-term solutions. Because it takes all of us to create a joyful region where every person can thrive.

Microsoft Disability Scholarship

This scholarship supports high school seniors living with a disability defined by WHO (World Health Organization — an impairment in a person’s body structure or function, or mental functioning (visual, hearing, mobility, cognitive, speech, or other disability). Eligible applicants must plan to study Engineering, Computer Sciences, Computer Information Systems, Law, Business (including Paralegal, Pre-Law, Finance, Business Administration, or Marketing) at an accredited two- or four-year college, university, or vocational-technical school. This scholarship is a $5,000 award with up to eight (8) scholarships granted.

Law Education - Higher Education Computer Science & Engineering +4 more

Strategic Projects: Program & Staff Grants

M J Murdock Charitable Trust
Private
United States
More than US $50,000
The M J Murdock Charitable Trust offers the Strategic Projects: Program & Staff Grants to support nonprofits in the Pacific Northwest. These grants focus on capacity-building for mission-driven projects and infrastructure investments. Eligible organizations must demonstrate a commitment to community flourishing, with funding available for new programs or expansion of existing ones. The Trust prioritizes initiatives that align with its strategic goals, fostering sustainable nonprofit growth and impact in the region.
Art & Culture Education Community Services +6 more

Zimmerman, Edward and Beverly Memorial Scholarship Fund

Noble County Community Foundation
Private
United States
US $1,000
The Zimmerman, Edward and Beverly Memorial Scholarship Fund offers $1,000 to West Noble High School seniors pursuing higher education at a college or university, with priority given to those demonstrating community service and maintaining a GPA between 2.50 and 3.00. Preference is also given to students studying agriculture, education, social work, or accounting. This scholarship reflects the values of its donors, Edward and Beverly, who were dedicated community members and supporters of local education.
Mathematics Education Human & Social Services +5 more

Strategic Projects: Equipment & Technology Grants

M J Murdock Charitable Trust
Private
United States
More than US $50,000
The M J Murdock Charitable Trust offers Strategic Projects: Equipment & Technology Grants to nonprofits in the Pacific Northwest. These grants focus on capacity-building projects and essential equipment, requiring recipients to cover at least 50% of costs. Eligible organizations include 501(c)(3) nonprofits and tribal entities. Priority is given to projects enhancing community services, education, and environmental stewardship, supporting initiatives that foster human flourishing and demonstrate diversified funding.
Art & Culture Education Community Services +6 more

Exemplary Pathways to STEM Graduate Education: Implementation

Alfred P Sloan Foundation
Private
United States
Up to US $500,000
The Alfred P. Sloan Foundation's Creating Equitable Pathways to STEM Graduate Education initiative aims to foster partnerships between Minority Serving Institutions (MSIs) and graduate programs to enhance equitable learning environments. Grants of up to $500,000 will support projects addressing systemic barriers, promoting effective practices, and ensuring seamless transitions from MSIs to advanced degrees in various STEM fields. The initiative seeks to create lasting impacts on student access and success in graduate education.
Astronomy & Astrophysics Biology Chemistry +10 more

Strategic Projects: Capital Grants

M J Murdock Charitable Trust
Private
United States
More than US $100,000
The Strategic Projects: Capital Grants by the M J Murdock Charitable Trust offer vital funding opportunities for nonprofit organizations in the Pacific Northwest. These grants support transformative projects that enhance community well-being through construction, renovation, and infrastructure investments. Eligible entities include 501(c)(3) nonprofits and government entities. The Trust emphasizes projects that demonstrate strong community impact and funding diversification, ensuring sustainable growth and lasting benefits for the communities served.
Nonprofit Growth & Development Art & Culture Education +6 more

Exemplary Pathways to STEM Graduate Education: Planning

Alfred P Sloan Foundation
Private
United States
Up to US $75,000
The Alfred P. Sloan Foundation's Creating Equitable Pathways to STEM Graduate Education initiative aims to foster partnerships between Minority Serving Institutions (MSIs) and graduate programs. By addressing barriers in graduate education, the initiative seeks to promote equitable learning environments. Planning grants will support collaborations that assess needs and develop systemic changes to enhance pathways for students in STEM fields, ensuring that all students can thrive in their academic pursuits.
Astronomy & Astrophysics Biology Chemistry +10 more

Exemplary Pathways to STEM Graduate Education: Seed

Alfred P Sloan Foundation
Private
United States
Up to US $250,000
The Alfred P. Sloan Foundation's initiative, "Creating Equitable Pathways to STEM Graduate Education: Seed," aims to enhance graduate education access for students from Minority Serving Institutions (MSIs). The program provides grants of up to $500,000 to foster partnerships between MSIs and various higher education institutions. Projects should focus on overcoming barriers to success in graduate studies, including recruitment and admission processes, thereby promoting equitable learning environments in STEM fields.
Astronomy & Astrophysics Biology Chemistry +10 more

Margaret Thorne-Dilley Scholarship for Science Teachers Scholarship

Beckley Area Foundation
Private
United States
Unspecified amount

Mission Statement

Beckley Area Foundation exists to inspire and facilitate generous charitable giving that advances our community.

The Beckley Area Foundation is committed to enriching lives and strengthening communities across Southern West Virginia.

Scholarship

Supporting Student Success

The Beckley Area Foundation proudly manages scholarship funds established by individuals, businesses, and organizations dedicated to helping students pursue higher education. Many of these scholarships are tailored for specific schools, fields of study, or graduates from local high schools, while others offer broader opportunities. No matter the path, our scholarships aim to support students from our region as they work toward achieving their educational goals.

Margaret Thorne-Dilley Scholarship for Science Teachers Scholarship

Eligibility

Equally weighted as a need and merit based award for a Raleigh County high school graduate with a 3.5 cumulative GPA; Pursuing baccalaureate degree in education at an accredited institution; Preference will go to students pursuing a science field including the biological, physical and natural sciences. If none apply with the preferences listed, mathematics will also be considered.

Education Educational Access & Equity Education - Higher Education +5 more

Menasha Corporation Foundation Grant

Menasha Corporation Foundation
Corporate
United States
Unspecified amount
The Menasha Corporation Foundation, established in 1953, supports nonprofit organizations across North America, focusing on community betterment, education, environmental sustainability, and health initiatives. Grants are awarded to projects that enhance the lives of individuals and strengthen communities, particularly in areas where Menasha Corporation operates. Eligible organizations must be tax-exempt and prioritize non-public funding. The foundation also encourages involvement from Menasha Corporation employees in supported projects.
Art & Culture Education Basic Human Needs +5 more

Pat and John MacTavish Fund

Grand Haven Area Community Foundation
Private
United States
Unspecified amount
The Pat and John MacTavish Fund, established in 2007 by John Mac Tavish in memory of his wife Pat, provides scholarships aimed at encouraging young women to pursue higher education in the hard sciences. Awarded by the Grand Haven Area Community Foundation, scholarships are competitive and based on criteria such as financial need and academic achievement. Applicants from Northern Ottawa County or specific school districts are eligible. The fund emphasizes the importance of education in fields such as math, chemistry, and computer science.
Education - Higher Education Educational Access & Equity Computer Science & Engineering +6 more

Cecelia Springmeyer Memorial Scholarship

Decatur County Community Foundation Inc.
Private
United States
More than US $1,000
The Cecelia Springmeyer Memorial Scholarship, managed by the Decatur County Community Foundation, aims to support North and South Decatur students pursuing post-secondary education in law enforcement, criminal justice, animal husbandry, agronomy, or teaching. Applicants must reside within the Decatur County Community Schools district and may receive a minimum scholarship of $1000 to ease their educational costs. For more details, visit ndsdscholarships.com.
Academic Scholarship Programs Education - Higher Education Law +5 more

Susan Falsetti-Burdett Memorial Scholarship Fund for Music

Armstrong County Community Foundation (The Community Foundation Serving the Heart of Western Pennsylvania)
Private
United States
Unspecified amount

Armstrong County Community Foundation

The Armstrong County Community Foundation, a public nonprofit corporation,

  • Gives grants, scholarships, and organizational support to address the needs of our community.
  • Builds a permanent endowment to help our donors create a legacy through this endowment.
  • Promotes informed philanthropy to increase and sustain charitable resources for the region.
  • Provides leadership and builds partnerships to identify and solve community issues.

Susan Falsetti-Burdett Memorial Scholarship Fund for Music

Born in Kittanning in 1957, Susan Burdett was the daughter of Aldo and Dorothy (Trenchik) Falsetti, and was a lifelong resident of our community. Susie was a loving daughter, sister, mother, wife, and friend. She taught music to many over the years, and also taught at Divine Redeemer School. She was caring, compassionate, sharing and understanding. Her charity will live on through this Susan Falsetti-Burdett memorial Scholarship Fund for Music.

Scholarship Details

  • Available to High School Seniors
  • Nonrenewable

All ACCF Scholarships are merit based.

Education - Higher Education Music Theater +2 more

ARISE Grants

Appalachian Regional Commission
State/Local Government
Adair County, Kentucky, Adams County, Ohio +428 more
Up to US $10,000,000
The ARISE Grants, offered by the Appalachian Regional Commission, aim to drive regional economic transformation across 13 Appalachian states. With funding of up to $63.5 million for implementation grants and $10 million maximum awards, the initiative supports collaborative projects that enhance community capacity and economic growth. The program encourages innovative partnerships to strengthen local economies and achieve socioeconomic parity, benefiting over 26 million residents in the Appalachian Region.
Community Development & Revitalization Economic Services & Development Workforce Preparation & Job Readiness +1 more

James A Wharton Scholarship

Community Foundation of North Central Washington
Private
United States
Unspecified amount
The James A Wharton Scholarship, established by the Community Foundation of North Central Washington, supports students from Chelan and Douglas Counties pursuing trade education, particularly in collision repair. Open to graduating seniors and nontraditional students, this scholarship encourages enrollment in vocational programs, emphasizing a commitment to learning. Recipients may renew their scholarships by reapplying competitively, ensuring continued support for those dedicated to advancing their skills in the trades.
Mechanical Engineering Vehicle Restoration Automotive Safety +4 more

Operating Grants for Nonprofits in Alabama Highlights

Looking for operating grants for nonprofits in Alabama?


Read more about each grant below or start your 14-day free trial to see all operating grants for nonprofits in Alabama recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Operating Grants for Nonprofits in Alabama

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Operating grants for nonprofits in Alabama grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

35 Operating grants for nonprofits in Alabama over $25K in average grant size

25 Operating grants for nonprofits in Alabama over $50K in average grant size

26 Operating grants for nonprofits in Alabama supporting general operating expenses

100+ Operating grants for nonprofits in Alabama supporting programs / projects

2,000+ Grants on Instrumentl focused on Art & Culture

2,000+ Grants on Instrumentl focused on Human & Social Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Operating grants for Nonprofits in Alabama?

Most grants are due in the second quarter.

Q1
20.7%
Q2
28.0%
Q3
27.0%
Q4
24.3%

Typical Funding Amounts

What's the typical grant amount funded for Operating Grants for Nonprofits in Alabama?

Grants are most commonly $10,000.

$250 $250 Min.
$10,000 $10 K Median
$522,234 $522.2 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for Alabama?

Grants are most commonly $70,566.

$70,566

Total Number of Grants

What's the total number of grants in Operating Grants for Nonprofits in Alabama year over year?

In 2024, funders in Alabama awarded a total of 24,908 grants.

2022 22,444

2023 22,303

2024 24,908

Top Grant Focus Areas

Among all the Operating Grants for Nonprofits in Alabama given out in Alabama, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Operating Grants for Nonprofits in Alabama changing over time?

Funding has increased by 16.90%.

2022 $1,451,827,061

2023 $1,499,071,857
3.25%

2024 $1,752,393,768
16.90%

Alabama Counties That Receive the Most Funding

How does grant funding vary by county?

Jefferson County, Montgomery County, and Lee County receive the most funding.

County Total Grant Funding in 2024
Jefferson County $823,975,842
Montgomery County $214,746,942
Lee County $129,591,925
Mobile County $117,873,781
Madison County $87,089,251