Best Operating Grants for Nonprofits in Alabama

The Sonny Greenwood Calzaretta Scholarship, offered by the Pride Foundation, supports LGBTQ+ students from rural communities facing isolation and limited access to resources. Established to honor the legacy of Brian M. Day, this scholarship aims to empower students pursuing post-secondary education while addressing systemic barriers. It prioritizes those demonstrating a commitment to justice and who have experienced challenges such as family rejection or economic hardship. The scholarship is part of a broader initiative to uplift diverse voices within the LGBTQ+ community.

Fall 2026 Early Childhood Education Funding Cycle

Overall Early Childhood Education Program Blueprint

The Stranahan Foundation’s Early Childhood Education grant program supports efforts to improve access to high-quality early care and education for young children (birth to five), especially those from low-income families. We do this by investing in strategies that strengthen, support, and retain a high-quality, thriving early educator workforce.

The Foundation has a history of supporting professional development (PD) and learning systems through its Provider strategy (). We believe strong professional development systems are essential for building a skilled early childhood workforce and creating positive learning environments for young children.

The Fall 2026 funding cycle is available for organizations that align with this Provider strategy.

Funding Opportunity

This funding opportunity will provide up to $750,000 to support early childhood education providers in strengthening existing professional development (PD) systems. Funding is intended to improve a specific area of an established PD system—not to build a brand-new system from scratch or put the foundational elements in place.

What kind of improvements can funding support?

Organizations should focus their projects on strengthening their professional development systems. The Stranahan Foundation defines a strong professional development system as one that includes:

• Connect learning opportunities that build on one another over time.
• Use adult learning best practices.
• Align staff learning to educator competencies, credentials, career growth, or compensation.
• Provide learning experiences that are individualized, scaffolded, and responsive to educators’ needs, experience, and goals.
• Have dedicated leadership and organizational capacity to support ongoing implementation.

• Gather regular feedback from staff and families.
• Use standardized assessment and evaluation tools to understand what is working and where improvements are needed.
• Make ongoing improvements based on what is learned.
• Support reflective practice, peer learning, and collaborative inquiry among educators.

• Offer both individual and group learning opportunities, such as training, professional learning communities, coaching, and mentoring.
• Provide learning opportunities on an ongoing basis rather than in a one-and-done situation.
• Connect internal and external learning opportunities to make the best use of available resources.
• Support classroom implementation through observation, modeling, feedback, and continuous improvement cycles.

• Provide learning experiences that are practical, relevant, and easy to apply in daily work.
• Include fundamental topics such as family engagement, effective instruction, developmentally appropriate practice, and classroom management.
• Align with established standards, research, and effective practices in the early childhood field.
• Equip educators to support all learners, including multilingual learners, children with disabilities, and children impacted by trauma or adverse experiences.

The Leonard Litz LGBTQ+ Foundation, via its TransPLUS Resource Center, supports transgender, gender-nonconforming, non-binary, and intersex individuals. By providing grants and resources, the Foundation aims to address urgent needs in healthcare, housing, and legal services while fostering community connections. They build peer-support networks, publish updates, and support initiatives to empower TGNCNBI individuals and their allies, ensuring that marginalized voices are heard and uplifted.

The Public Health Nursing initiative aims to enhance the health and wellness of American Indian and Alaska Native men by implementing a culturally sensitive case management model. Through this program, Public Health Nurses will provide preventive health services, facilitate access to care, and encourage healthy lifestyle choices. By promoting early identification and management of health issues, the initiative strives to improve overall community health outcomes through targeted, collaborative interventions.

The Louis Stokes Alliances for Minority Participation (LSAMP) Bridge to Doctorate Scholars Program, funded by the National Science Foundation, aims to recruit and retain minority graduate students in STEM fields. This program offers significant benefits, including a $32,000 annual stipend and $12,000 educational allowance for two years, fostering a supportive community through monthly dinners for Indigenous graduate students. Eligible applicants must be U.S. citizens, identify as American Indian or Alaska Native, and have participated in an LSAMP program.

The Culpeper Rotary Foundation Scholarship supports residents of Culpeper County pursuing a four-year degree. With a $1,000 award renewable for four years, applicants must demonstrate financial need and maintain a GPA of 2.5 or higher. The Northern Piedmont Community Foundation manages the scholarship application process, emphasizing community involvement. This initiative reflects NPCF's commitment to enhancing educational opportunities in the region, ensuring that local students have the support they need to succeed in their academic pursuits.

Homecare Assistance Grant

MS Focus understands the daily needs and challenges that must be met by both those with MS and their caregivers. In order to meet these needs in the most timely and efficient way possible, our Homecare Assistance Grant connects you to the best available local services. Should resources within your community not be available, direct support may be provided on a temporary basis.

Available Services include:

• Home Care - Personal hygiene services, light housekeeping, grocery shopping, meal preparation, and transportation to and from appointments are all services that can be provided for a limited time.
• Therapy Visits - Based upon individual need, an appointment with an occupational, physical, or speech therapist can be arranged. Through education and training, these therapists can help to foster independence, self-esteem, and better quality of life for the person living with MS.
• Respite Care - Respite allows primary caregivers the opportunity to tend to themselves, or other family business, with the assurance that their loved one is being cared for by a properly trained individual. This service is provided on a short-term basis for a scheduled period of time. 
• Coming Home - Returning home from a stay at the hospital can be a difficult time of transition. We offer a four-hour visit from an aide who will meet the patient at the hospital, provide transportation home, and then get the patient settled comfortably at home.

The James Knott Memorial Scholarship, established by the New Mexico Manufactured Housing Association, supports graduating high school seniors residing in manufactured homes. Awards of up to $1,000 are given annually to students with a minimum GPA of 3.0 who attend a nonprofit or public educational institution full-time. Applicants must provide proof of residency, a written statement of financial need, and a reference from a teacher or counselor. This scholarship aims to empower students to achieve their educational goals.

The Hyperoxaluria Fund, managed by the HealthWell Foundation, aims to alleviate financial burdens for underinsured patients suffering from hyperoxaluria, a condition characterized by excessive oxalate in urine. This fund assists with prescription drug copays and insurance premiums, providing vital support for treatments. In 2024 alone, HealthWell allocated over $1.2 billion in grants, ensuring access to essential medications for those in need. The organization is committed to improving healthcare access and reducing disparities for affected individuals.

Cures Within Reach

Cures Within Reach is the philanthropic leader in drug, device and nutraceutical repurposing research, which has the potential to transform the lives of patients with unsolved diseases by delivering treatments that can be used in the near-term. Our focus: we find and fund proof-of-concept clinical trials that, once successful, de-risk and catalyze follow-on funding, building the clinical evidence required for regulatory approval or to support off-label use by patients everywhere.

Clinical Repurposing Research to Impact US Veterans/Military

This Request for Proposals (RFP) from Cures Within Reach (CWR) is seeking clinical repurposing trials from US-based research institutions using already approved treatments to address unmet and high-priority medical needs of US veterans and/or active US military, such as mental health, post-traumatic stress disorder (PTSD) and brain injuries. Our strongest preference is for proof of concept, pivotal, Phase I or Phase IIA clinical repurposing trials. Eligible trials may be conducted at accredited US-based academic, nonprofit and governmental research institutions and/or health systems involved with medical research, including Veterans Administration (VA) health systems and hospitals. 

Repurposed therapies must be approved and/or generally recognized as safe for human use by some regulatory agency, such as the US Food and Drug Administration, European Medicines Agency, Health Canada or Japan’s Pharmaceuticals and Medical Devices Agency, and may include drugs, devices, nutraceuticals or diagnostics, as well as combination therapies. These repurposed therapies must be tested in a new indication for which they are not already approved or used widely in clinical practice as standard of care. Repurposed therapies also may be added to current standard of care to improve patient outcomes and/or quality of life.

The National Park Service (NPS) invites applications for Master Cooperative Agreements from participants in the Cooperative Ecosystem Studies Units (CESU) network across various regions. This initiative fosters collaboration among federal agencies, tribes, academic institutions, and conservation organizations to enhance resource stewardship. With 390 non-federal partners and 15 federal agencies, the CESU network supports interdisciplinary projects addressing diverse environmental and cultural heritage issues. Applications are continually accepted until the announcement's closing date.

Gropper Clement Legacy Scholarship

To provide financial support to graduates of Huron, James Valley Christian, Kadoka and Miller High Schools.

The Mantle Cell Lymphoma Fund, managed by the HealthWell Foundation, provides financial assistance to underinsured patients diagnosed with Mantle Cell Lymphoma. The fund covers prescription drug copays and Medicare Part B premiums, with a maximum award of $8,500. Eligible patients must have insurance that covers their medication and meet specific income guidelines. The foundation aims to reduce financial barriers to essential treatments, ensuring that patients receive necessary care without undue financial strain.

The Parkinson Family Foundation Grant supports organizations focusing on Food & Water, Faith & Evangelism, and Health & Humanitarian Efforts. Applications are open year-round, with grants ranging from $1,000 to $5,000; larger requests are typically declined. Eligible applicants include schools, state governments, and 501(c)(3) nonprofits. The Foundation emphasizes selectivity and prioritizes organizations with established relationships and those promoting American ideals like freedom and justice.

The Metabolic Dysfunction-Associated Steatohepatitis Fund, established by the HealthWell Foundation, aims to alleviate financial burdens for underinsured patients facing chronic illnesses. It provides critical support for expenses related to prescription copays, insurance premiums, and transportation for treatment. With a maximum award of $8,000, the fund ensures that individuals can access necessary healthcare services without financial strain. This initiative emphasizes the commitment to improving health outcomes for those affected by metabolic dysfunction-associated steatohepatitis.

The Fair Housing Initiatives Program (FHIP) aims to combat discriminatory housing practices through funding provided to various organizations. Established by Congress in 1988 and made permanent in 1992, FHIP supports entities that educate the public and enforce fair housing rights. The program offers competitive grants across four initiatives, including the Private Enforcement Initiative, which enables national non-profit organizations to investigate violations and uphold fair housing laws effectively.

The Zonta Club of Greater Sandusky High School STEM Scholarship Fund provides financial support to female high school seniors from Erie, Huron, or Ottawa County, Ohio, who plan to pursue a degree in STEM or medical fields at accredited institutions. Established by the Zonta Club, this scholarship aims to empower young women to contribute positively to their communities by facilitating access to higher education opportunities. Since its inception, it has fostered academic growth and leadership among recipients.

Powering Economic Opportunity Fund

Converting America's economic transformation into lasting earnings gains for workers — by backing the employer-side job designs and workplace practices that a durable payer will carry forward.

Across the United States, the modernization of energy systems, physical infrastructure, and advanced manufacturing is creating sustained demand for skilled workers — electricians, welders, energy technicians, construction managers, and industrial specialists — even as the broader labor market has slowed. The Bureau of Labor Statistics projects that energy-related occupations will be among the fastest-growing through 2034, and critical trades face significant shortages as experienced workers retire. 

Geopolitical uncertainty and conflicts only accelerate these trends and the need to focus on energy security. At the same time, AI-driven disruption continues to displace entry-level knowledge roles, creating a strong and underserved candidate pool for durable trade pathways.

Investments are expanding access to skilled trades training, but a critical gap remains between funding workforce programs and achieving lasting employment outcomes. Too many workers complete training without staying in quality jobs, and too few investments address the employer practices that improve retention, advancement and long-term earnings.

As part of our multiyear partnership with Families and Workers Fund, GitLab Foundation is pleased to announce a $4M open call for the Powering Economic Opportunity Fund — flexible grants of up to $500,000 supporting organizations that partner directly with employers, unions and industry to strengthen work-based learning, improve job quality and connect workers to durable, living-wage careers. Round 2 invests in employer-side practice change — the job designs and workplace practices that help workers stay, advance, and build careers — and in the durable financing that sustains those practices after the grant ends.

The Davis-Kozoll Scholarship, established in 2019 by the Sandia Foundation, supports students from northwest New Mexico pursuing higher education in science or human service disciplines. Scholarships range from $1,000 to $5,000 and can be renewed annually based on academic progress. Applicants must have a minimum GPA of 2.0, demonstrate community ties, and may pursue various degrees or vocational certificates. Priority is given to students from specific local communities, enhancing educational opportunities in the region.

The Princess Grace Awards support early career artists in theater, dance, and film with unrestricted cash grants of $15,000. Open to U.S.-based artists, the awards recognize both creative generators and performance-based creatives. Nominations are required from non-profit organizations or previous award winners, ensuring a robust evaluation of artistic merit. With a focus on nurturing talent, the Princess Grace Foundation honors the legacy of Princess Grace of Monaco by fostering the next generation of artists.

The Luther Halsey Gulick Award, presented by SHAPE America, recognizes individuals with over ten years of membership who have made outstanding contributions to health and physical education. This prestigious honor is awarded annually to a candidate selected for their exemplary leadership and service in the field. Nominations are carefully evaluated based on the candidate's impact on the profession and their ability to inspire future generations to lead healthy, active lives.

The Measurement and Evaluation Honor Award recognizes exceptional contributions by a SHAPE America professional towards the Measurement and Evaluation SIG's mission. This prestigious accolade celebrates those who advance health and physical education practices, inspiring educators to enhance student well-being. Eligibility requires current membership in SHAPE America and the Measurement and Evaluation SIG, ensuring that only dedicated professionals are honored. This award embodies the commitment to fostering excellence in educational environments, ultimately aiming to prepare all children to lead active, healthy lives.

The Native Forward Direct Scholarship supports American Indian and Alaska Native students by providing mid-year funding opportunities to alleviate educational costs. With over 50 years of experience, Native Forward has empowered more than 22,000 students from diverse backgrounds. This scholarship recognizes the limited access these students face in higher education and aims to enhance their academic journeys while fostering community engagement and mentorship through a strong alumni network.

The Measurement and Evaluation Lifetime Achievement Award recognizes a distinguished SHAPE America professional who has significantly impacted measurement and evaluation in health and physical education. This prestigious award highlights the importance of scholarly achievement and the influence of national standards in enhancing educational practices. It aims to honor those who have dedicated their careers to improving the quality of health and physical education, ultimately promoting healthier lifestyles for students across the nation.

The Clark and Ruby Baker Foundation Grant aims to support charitable organizations that align with the philanthropic mission of the Baker family, focusing on Methodist-affiliated educational institutions, aid for disadvantaged children, and assistance for the sick in Georgia. The Foundation considers funding for construction projects of educational and medical facilities, ensuring that grants are awarded to meet specific community needs and promote long-term benefits.

About Legacy Foundation

Legacy Foundation is the community foundation for Lake County, Indiana. We connect people, knowledge, and funding to build an equitable, accessible, and inclusive Lake County, now and for generations to come.

Legacy Foundation is supported by a broad base of individuals, families, and businesses connected by the desire to improve Lake County, Indiana. With a growing portfolio of over 300 funds and approximately $80 million in assets, Legacy Foundation is a trusted source for philanthropic giving in the region.

For over 30 years, Legacy Foundation has been empowering people, providing strategic leadership, and impactful philanthropic support to create an equitable Lake County where all people thrive.

Mission Statement

Transforming Lake County by providing strategic leadership and impactful philanthropic support to ensure equitable opportunity for all communities that we serve.

Vision Statement

Create an equitable Lake County where all people thrive.

Peter V. Westhaysen Medical Education Scholarship

Scholarships are available for post-secondary undergraduate, graduate and post-graduate students pursuing a degree to become a physician or nurse at an accredited university. The purpose of the scholarship is to assist the student with the costs of tuition, fees, and books. The Advisory Committee consider two basic criteria: academic achievement and financial need.

Syndax Pharmaceuticals, Inc.

At Syndax, we are determined to realize a future in which people with cancer live longer and better than ever before. We believe that it takes a community to build a great medicine, and that is why we are working to set the new standard for developing medicines in the field of oncology – one that revolves around collaboration, shared learning, and excellence.

Syndax’s mission is to obtain regulatory approval and commercialize drugs that extend and improve the lives of cancer patients by drawing on the newest scientific research and advances, collaborating with determined problem solvers, and identifying value in overlooked aspects of science.

Educational Funding

At Syndax, we are committed to the goal of supporting objective, balanced and scientifically rigorous education that furthers improvements in science, medicine, and patient care. We accomplish this goal, in part, by providing grants for independent medical education (IME) programs. These can include live, online, and/or enduring programs that educate healthcare providers (HCPs), patients, or caregivers. Programs that are funded via Syndax medical education grants must be primarily dedicated, in both effort and time, to medical, health or scientific topics that are objective, balanced, unbiased, and scientifically rigorous. Medical education grants must never be made with the intent to directly or indirectly reward, influence or encourage the recipient to prescribe, purchase, sell or arrange for any Syndax product.