Best Unrestricted Grants for Nonprofits in Alabama

The NIH Director's New Innovator Award supports creative early-stage investigators pursuing innovative research with transformative potential for science relevant to the NIH mission. Applications are encouraged across all NIH-related fields, enhancing support for emerging talent. This award is part of the NIH Common Fund's High-Risk, High-Reward Research Program, which aims to cultivate groundbreaking research and foster the next generation of scientists.

The FY 2027 Department of War Multidisciplinary Research Program of the University Research Initiative (MURI) aims to fund U.S. academic teams conducting innovative research to tackle complex challenges for the Department of War. Established in 1985, MURI promotes collaboration among diverse scientific disciplines, enhancing the defense workforce and addressing critical areas of interest through multidisciplinary research efforts at U.S. universities.

The NIH Research Education Program (R25) aims to enhance research education activities, particularly for individuals from diverse backgrounds underrepresented in the biomedical and behavioral sciences. This program encourages these individuals to pursue advanced studies and careers in research through mentoring networks and educational experiences, fostering a more inclusive and diverse research workforce.

The Hanna H. Gray Fellows Program, supported by the Howard Hughes Medical Institute, aims to enhance diversity in the academic research community. It provides funding of $250,000 and a $20,000 annual expense allowance for early-career researchers committed to fostering an inclusive scientific culture. Eligible applicants must hold a PhD or MD, commit to at least 75% research effort, and have no more than 24 months of postdoctoral experience. This initiative empowers fellows to become leaders in science.

The Kelley Foundation

The Kelley Foundation was established by Robert and Judy Kelley and their daughter Marla. The Kelleys are native Oklahomans and longtime residents of Southern Oklahoma.

The foundation is primarily focused on humanitarian projects in Oklahoma, with an emphasis on Southern Oklahoma. Our mission is to develop and strengthen our community, state, and nation by providing essential resources to those in need.

The Kelley Foundation Grant

The Kelley Foundation is a private, charitable foundation, incorporated under the laws of the State of Oklahoma and operated exclusively for providing support through its gifts and grants to religious, charitable, scientific, and educational institutions which are qualified under section 501(c)(3) and which are not private foundations within the meaning of section 509(a) of the Internal Revenue Service Code.

Steve Wagner Scholarship

Steve Wagner retired as executive director of the American Council of Engineering Companies of Michigan (ACEC/M) in 2003 after 34 years of service. As a member of the Capitol Club and Michigan Society of Association Executives, Steve was well respected by his peers and colleagues and is known for his honesty and integrity.

Steve and his wife, Lana, were married in 1965 and have two daughters, Shelley and Whitney. Throughout his career, Steve has been a proponent of community service and has given many hours himself to church and community programs. Steve also has been a strong proponent of education. ACEC/M has established this scholarship in honor of Steve Wagner to award engineering and surveying students who, like Steve, are active in the community and find it important and necessary to give something back.

The NIH Independent Scientist Award (K02) aims to support the development of promising scientists, providing three to five years of salary support and protected time for focused research. This funding opportunity is specifically for basic experimental studies involving human participants, classified as clinical trials. Eligible applicants must demonstrate a need for intensive research to advance their careers, and the proposed projects should align with the interests of the participating NIH Institutes and Centers.

The Foundations of Trusted Systems initiative seeks innovative research to develop secure, resilient, and affordable technologies for Command, Control, Communications, Computers, and Intelligence (C4I) and Cyber systems. This Broad Agency Announcement (BAA) aims to establish trusted foundations for hardware and software, building on previous work to enhance information processing systems. Researchers are encouraged to submit white papers for evaluation and potential funding.

NASA's Early Stage Innovations for In Situ Resource Utilization (ESI26-ISRU) aims to advance lunar water purification technologies. This initiative invites proposals from U.S. institutions to address civil-space needs, fostering collaboration among tenured and untenured faculty. With awards expected to commence in June 2027, NASA plans to allocate approximately three awards, contingent on proposal quality and funding availability. This solicitation emphasizes the importance of innovative solutions for sustainable lunar exploration.

The National Aeronautics and Space Administration (NASA) invites U.S. institutions of higher education to submit proposals for the Early Stage Innovations (ESI26) program. This initiative focuses on innovative, early-stage space technology research aligned with civil-space needs. Proposals are sought on topics such as advanced manufacturing for lunar missions and computational fluid dynamics. Only U.S. institutions are eligible, with a requirement for the Principal Investigator to be a tenured or tenure-track faculty member.

The NASA Innovative Advanced Concepts (NIAC) Phase I program invites proposals for groundbreaking aerospace concepts, aiming to transform potential in aeronautics. This initiative supports innovative research through multiple award phases, focusing on Phase I requirements and evaluation criteria. A virtual forum will be held on October 7, 2026, to discuss the Appendix’s details and clarify submission guidelines. Additional information will be available on the NSPIRES page, ensuring participants are well-informed about the process.

The NIH Common Fund is planning to issue a NOFO to continue the Bridge2AI program, which aims to develop AI-ready datasets and best practices for biomedical research. This next stage will leverage these datasets to address significant health challenges and foster multidisciplinary collaboration. The initiative will support 3-5 Centers focused on trustworthy AI in biomedical research, creating frameworks for reproducibility, transparency, and advancing the AI workforce in health sciences.

The Japanese-Language Education Project Grant supports initiatives that enhance Japanese language education across various regions. Offered by the Japan Foundation, Los Angeles, this grant targets workshops, seminars, and original projects that connect language learning with Japan Studies. Eligible applicants include non-profit educational organizations in the U.S. Projects should benefit multiple programs, ensuring a broad impact on Japanese language education. The deadline for applications is two months before the project start date, which must be between April 1, 2025, and March 31, 2026.

The Nature Awards for Inspiring Women in Science, particularly in the Science Outreach category, honors initiatives that empower girls and young women in STEM fields. With a focus on engagement and retention, the awards aim to celebrate projects that encourage participation in natural sciences, technology, engineering, mathematics, and medicine. Winners will receive significant cash prizes and opportunities for mentorship, creating pathways for future generations of women in science.

The National Institute on Aging (NIA) is announcing a funding opportunity to support the Exceptional Longevity Data Management and Coordinating Center (EL DMCC). This initiative aims to enhance the management of large, diverse datasets and facilitate collaborative research across NIA projects. Core functions include data integration, AI/ML infrastructure development, and maintaining the ELITE Portal for secure data access. This NOFO encourages innovative approaches to longevity research, though applications are not currently being solicited.

The NIH Support for Conferences and Scientific Meetings (R13) grant aims to facilitate high-quality conferences that contribute to public health and the scientific missions of NIH Institutes and Centers. Key application deadlines range from April 2024 to January 2027, providing vital opportunities for researchers to gather and share knowledge. This grant is particularly focused on enhancing the impact of scientific dialogue in critical health areas.

The Ruth L. Kirschstein National Research Service Award (NRSA) offers predoctoral training grants aimed at enhancing clinical and translational science. Administered by the NCATS, this program supports institutions in training aspiring researchers for a PhD or equivalent, ensuring a diverse cohort of scientists equipped to tackle pressing health challenges. The ultimate goal is to cultivate a skilled workforce capable of advancing biomedical research and addressing community health needs effectively.

The PLTW Gateway program, supported by Lockheed Martin, offers grants for schools to implement STEM and CTE-aligned curricula. Aimed at enhancing educational access for students, it provides funding of $10,000 for the 2026-2027 academic year. Eligible schools include public and charter institutions across the U.S. This initiative, part of a long-standing partnership since 2007, addresses the critical need for future engineers and scientists, benefiting over 77,000 students through innovative coursework.

The NIH Independent Scientist Award (K02) supports the development of outstanding scientists by providing three to five years of salary support and protected time for newly independent researchers. This funding opportunity is specifically for applicants proposing research that does not involve leading an independent clinical trial, allowing them to gain experience in trials led by others. Key deadlines for applications span from June 2024 to February 2027.

The Air Force Basic Research Sciences Conference and Workshop Support program encourages proposals from U.S. institutions of higher education and nonprofit organizations for conferences and workshops that promote research and technology interchange. These events are vital for sharing recent findings and educational techniques in key scientific areas. The program specifically invites Historically Black Colleges and Universities, Minority-serving Institutions, and Tribal Colleges to participate, aiming to foster collaboration and knowledge exchange among researchers.

The NIH Independent Scientist Award (K02) aims to support the development of independent scientists and enhance their research capabilities. This award offers salary support and protected time for three to five years, specifically for those leading independent clinical trials or feasibility studies. Applicants must demonstrate a need for focused research to advance their careers. Key deadlines for applications span from June 2024 to February 2027, catering to various submission types including standard and AIDS-related grants.

The Nature Awards for Inspiring Women in Science celebrate outstanding contributions by women in STEM fields. These awards recognize early-career female researchers who demonstrate exceptional achievements, face challenges, and inspire the next generation through outreach. Winners receive prizes totaling $50,000, mentorship opportunities, and invitations to prestigious ceremonies. This initiative promotes inclusivity and aims to enhance the representation of women in science, thereby supporting a diverse and equitable scientific community.

The AHRQ Mentored Clinical Scientist Research Career Development Award (K08) supports individual career development for health services researchers. This funding opportunity aims to cultivate a diverse group of trained researchers who can effectively address AHRQ's mission and priorities. Through mentorship and structured programs, applicants are equipped to enhance their research skills and contribute meaningfully to the field of health services research.

About the Hertz Foundation

Empowering the Nation’s Most EXCEPTIONAL Innovators

The Hertz Foundation identifies and empowers the nation’s most exceptional innovators in science and technology, fueling a lifelong community dedicated to solving our most pressing problems.

Hertz Community

Awards & Recognition

We’ve established several awards to recognize and support Hertz community members who are accelerating solutions to significant real-world challenges, either through their individual careers or volunteering to strengthen the Hertz Foundation’s work. In addition to providing financial and professional support at a critical time, we also hope to generate more awareness within the Hertz community and inspire collaborations that build on the momentum.

Hertz Thesis Prize

The Hertz Thesis Prize recognizes fellows who publish exemplary doctoral theses with applications to real-world problems. Winners receive a $5,000 honorarium.

Exemplary Graduate Work

Since 1981, more than 60 fellows have been recognized with the Hertz Thesis Prize. Much of their work has led to successful patents, the formation of influential companies and contributed solutions to some of our most pressing challenges.

The PLTW Gateway Program Expansion, in partnership with Lockheed Martin, aims to enhance STEM education in schools across the United States. With a total grant of $10,000 for the 2026-2027 academic year, this initiative focuses on expanding existing PLTW Gateway programs, allowing schools to introduce new units and train additional teachers. Since 2007, Lockheed Martin's support has enabled over 300 programs, providing critical skills to more than 77,000 students nationwide.

The Ruth L. Kirschstein National Research Service Award (NRSA) Postdoctoral Research Training Grant supports institutions in developing clinical and translational science training programs. This program aims to enhance the research training of postdoctoral individuals holding doctoral degrees, ensuring a diverse pool of scientists equipped to tackle critical health challenges. Applications must be submitted by 5:00 PM local time of the applicant organization, and non-U.S. entities are not eligible.

The Rea Charitable Trust, established in 2009 by Mrs. Isabel McClintic Rea, prioritizes support for charitable organizations that focus on the arts. Administered by Comerica Bank & Trust, the trust provides funding through structured application periods for organizations based on their names. Eligible applicants must be 501(c)(3) organizations, limited to one application per year. The trust aims to uphold Mrs. Rea's legacy by fostering artistic endeavors within the community.