Best Small Grants for Nonprofits in American Samoa

The NIAID Physician-Scientist Pathway to Independence Award (K99/R00) aims to support new independent physician-scientists by facilitating their transition from postdoctoral research to tenure-track faculty positions. This program provides essential research funding to help awardees establish their careers in biomedical research, addressing the national shortage of physician-scientists. Applicants must propose research that does not lead an independent clinical trial, but may include mentorship in clinical trials.

The HDR Foundation Grant Cycle supports community organizations aligned with HDR's values, focusing on education, healthy communities, and environmental stewardship. This employee-funded initiative emphasizes the importance of employee engagement in grant proposals, requiring a clear scope of work and completion within a year. Eligible applicants include U.S.-based nonprofits, educational institutions, and tribal governments, while grants are not provided for faith-based organizations or individual support.

The Collaborative Program Grant for Multidisciplinary Teams, funded by the US Dept. of Health & Human Services: National Institutes of Health (NIH), supports integrated teams of researchers tackling ambitious projects that individual efforts cannot achieve. This program promotes collaboration among experts with complementary skills, aiming for significant advancements in their fields. Teams are encouraged to pursue innovative objectives that have the potential to transform research landscapes.

The American Bar Endowment's Opportunity Grant Program provides funding for innovative, boots-on-the-ground initiatives that address urgent legal needs of the public. This grant focuses on increasing access to justice for underserved populations, improving the justice system, and enhancing public understanding of legal rights. Eligible applicants include public charities and organizations directly impacting local communities, with a strong emphasis on projects that leverage technology and address immediate legal challenges.

The Medical Scientist Training Program (MSTP) aims to cultivate skilled clinician-scientist leaders to meet the nation's biomedical research demands. It supports domestic organizations in developing dual-degree training that integrates clinical and research education, leading to both a clinical degree (e.g., M.D., D.O.) and a Ph.D. Through comprehensive mentoring and career development, MSTP prepares trainees for impactful careers in health-related research, ensuring a robust pipeline of qualified scientists.

The HEAL Initiative aims to enhance therapeutic medical devices through team science research, focusing on the mechanisms that drive their effectiveness. The National Institute of Neurological Disorders and Stroke (NINDS) seeks to improve clinical outcomes by fostering interdisciplinary collaborations. This initiative invites teams with expertise in engineering, biology, and clinical care to explore innovative device-based therapies. By understanding how these devices work, the program hopes to optimize existing technologies and inspire new designs, ultimately improving patient care.

The National Biomedical Research Centers (NBRCs) aim to enhance biomedical research by providing advanced equipment, scientific expertise, and innovative human-based models. Supported by NIH and other federal agencies, this initiative focuses on reducing reliance on live animal models through the development of New Approach Methodologies (NAMs). The program invites applications that propose actionable plans to refine and replace animal use, promoting innovative research at centers with existing nonhuman primate colonies.

Bureau of Justice Assistance

The Bureau of Justice Assistance (BJA) was created in 1984 to reduce violent crime, create safer communities, and reform our Nation’s criminal justice system.

BJA strengthens the Nation’s criminal justice system and helps America’s state, local, and tribal jurisdictions reduce and prevent crime, reduce recidivism, and promote a fair and safe criminal justice system. BJA focuses its programmatic and policy efforts on providing a wide range of resources, including training and technical assistance, to law enforcement, courts, corrections, treatment, reentry, justice information sharing, and community-based partners to address chronic and emerging criminal justice challenges nationwide. 

Special Attorneys Program

This program will support state, local, Tribal, and territorial prosecuting agencies in assigning or hiring qualified prosecutors to serve full time as Special Attorneys within the National Fraud Enforcement Division or the Criminal Division or as Special Assistant United States Attorneys (SAUSAs) within a United States Attorney’s Office. These cross-designated prosecutors will investigate and prosecute fraud and other crimes committed by aliens within the United States (hereafter referred to as “criminal aliens”) and will investigate and prosecute crimes involving drug or human trafficking committed within the United States.

This grant program, authorized under Public Law 119-21, Title X, Subtitle A, Part II, Section 100055 (codified at 34 U.S.C. § 61101), is intended to strengthen investigative and prosecutorial capacity, expand intergovernmental coordination, and enhance the ability of jurisdictions to investigate and prosecute fraud and other crimes committed by aliens within the United States and drug and human trafficking crimes. The program is also intended to increase the availability of cross-designated prosecutorial personnel who can pursue these matters in coordination with federal authorities and contribute to the effective enforcement of applicable criminal laws.

The Engineering Biological and Biomedical Systems (EBBS) program, funded by the National Science Foundation (NSF), aims to advance our understanding of biological systems and improve human health through innovative engineering solutions. It supports research that combines mechanistic insights with experimental techniques to develop novel biomedical technologies, enhance biomanufacturing processes, and explore therapeutic applications. Projects focusing on engineering principles for biological responses and rehabilitation are encouraged, while drug design and clinical trials are outside the program's scope.

The Maximizing Investigators’ Research Award (MIRA) for Early Stage Investigators (ESI) by NIGMS aims to enhance research productivity and flexibility for early career scientists. This program consolidates funding into a single award, allowing investigators to pursue ambitious projects while reducing administrative burdens. By supporting diverse research initiatives, MIRA helps cultivate a new generation of innovative researchers, ensuring essential breakthroughs in fundamental science.

The National Science Foundation (NSF) is funding initiatives to enhance the value of scientific datasets through innovative artificial intelligence (AI) methods. This program aims to facilitate interdisciplinary research and unlock new insights by applying AI for feature extraction, metadata generation, and dataset integration. Proposals should ensure data security and promote collaboration with various sectors to advance AI-driven scientific discovery. By aligning with NSF priorities, researchers can contribute to cutting-edge science and technology for broader participation in STEM.

The Professional Formation of Engineers (PFE) initiative aims to enhance the engineering workforce through integrated research and education. It focuses on developing ethical engineers who can adapt to a changing technical landscape. PFE supports diverse training contexts, including formal education, internships, and community experiences, ensuring clear pathways into the profession. This initiative fosters collaboration among engineers, technical workers, and communities, enhancing the skills needed for global competition and technological advancement.

The Organizational Change in the Professional Formation of Engineers (ENGINEER:OC) initiative promotes innovative research and activities aimed at transforming engineering education and workforce development. Supported by the National Science Foundation (NSF), it seeks to enhance access to quality engineering programs across diverse institutions. Projects may involve implementing new curricular innovations or adapting existing models to different contexts, ultimately advancing the professional formation of engineers and fostering inclusive educational pathways.

The Bear Paw Resort Scholarship, offered by the Community Foundation for the Fox Valley Region, supports graduating seniors from White Lake High School who plan to pursue post-secondary education. With over $2 million available for scholarships in 2025, this initiative aims to empower students in their educational journeys. The scholarship is designed to assist with tuition costs, payable after the completion of the first semester, thereby encouraging academic success and community development.

The TESOL Leadership Mentoring Program connects TESOL members with experienced leaders for mentorship and professional development. Participants receive free registration to the annual convention, up to $1,000 for lodging, and the opportunity to build lasting relationships within the TESOL community. This program is designed for members in good standing, with a preference for individuals from underrepresented groups, fostering inclusivity and active participation in the association's initiatives.

The Tobacco Centers of Regulatory Science (TCORS) program, supported by the NIH and FDA, aims to foster research centers that enhance the scientific understanding of tobacco regulation. These centers will conduct hypothesis-driven projects on critical topics such as addiction, health effects, and marketing. By providing a multidisciplinary approach, TCORS seeks to inform public health strategies and ensure effective implementation of the Family Smoking Prevention and Tobacco Control Act.

This funding opportunity seeks to enhance awareness and education on viral hepatitis among high-risk populations and healthcare professionals. It focuses on two components: community education and professional training. By fostering coalitions and providing resources, the initiative aims to improve testing, treatment, and care for hepatitis B and C, ultimately reducing morbidity and mortality linked to these infections. The goal is to empower communities and healthcare providers with the knowledge and tools needed for effective prevention and intervention.

The CDC is offering FY 2027 funds for a cooperative agreement to enhance national surveillance for human prion diseases, or transmissible spongiform encephalopathies (TSEs), in the U.S. This initiative aims to confirm suspected cases and monitor emerging diseases through a specialized center utilizing advanced diagnostic techniques. Since 1997, this center has facilitated disease confirmation and trend evaluation, ensuring accurate surveillance and fostering confidence that novel prion diseases are not emerging in the country.

The NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed) grant aims to facilitate high-quality conferences that align with public health and scientific missions. Key deadlines include December 12, 2024, April 12, 2025, and August 12, 2025, among others, specifically for AIDS-related applications. This funding opportunity is provided by the US Department of Health & Human Services: National Institutes of Health (NIH).

The Teiger Foundation's Curatorial Research and Development Grant offers support for innovative curatorial practices within the contemporary visual arts sector. Designed to address gaps in funding, this grant provides up to $50,000 for curatorial research projects, including travel and collaborative investigations. It emphasizes the importance of experimentation and creativity while aligning with values of racial justice and environmental sustainability. The next Call for Proposals will open in Fall 2026, with funding opportunities available to U.S.-based curators.

The Teiger Foundation's Hosting Grant provides up to $75,000 for US-based curators or artistic directors to present contemporary visual art exhibitions that originated in different contexts. This grant encourages resource-sharing and collective learning, allowing institutions to expand their programming sustainably. It prioritizes projects affiliated with established non-profits, fostering community-building and positive change in the field of visual art while addressing issues of racial justice and climate crisis.

The NIDCR is inviting applications for the continuation or revision of ongoing clinical trials through the UH3 Clinical Trial Required grant. This opportunity supports extensions for completing trials or longer follow-up periods, as well as revisions that are well justified. Key deadlines for submissions are set from March 2025 to January 2028, with optional Letters of Intent encouraged thirty days prior to application due dates. Ensure compliance with the outlined requirements to enhance your chances of funding.

The Veterans Legacy Grants Program (VLGP) offers funding up to $400,000 to eligible entities for cemetery research related to Veterans’ interred in national, State, or Tribal cemeteries. It aims to create educational materials promoting community engagement and understanding of Veterans' histories. Administered by the Department of Veterans Affairs, the program provides resources for educational institutions to enhance public knowledge and appreciation of Veterans’ contributions and legacies.

The Teiger Foundation Programming Grant supports innovative visual arts projects led by curators at smaller non-profit organizations with budgets under $3.5 million. Grants of up to $150,000 are available for three years, funding development, realization, and documentation of exhibitions and related programs. The foundation emphasizes community engagement, racial justice, and artistic experimentation while encouraging collaboration with other cultural institutions. Note: The next Call for Proposals opens in Fall 2026.

The McKesson Foundation Grant provides funding up to $25,000 for organizations focused on improving health outcomes in underserved communities. Established in 1943, the foundation prioritizes health equity through strategic partnerships aimed at reducing cancer burdens, preparing healthcare professionals, and enhancing crisis response efforts. Eligible applicants include national and local nonprofits targeting specific regions in the U.S. and Canada. The foundation emphasizes projects that align with its mission and demonstrate significant community impact.

The Teiger Foundation Single Project Grant supports innovative visual arts projects at non-profit exhibition spaces with annual budgets exceeding $3 million. Focused on curatorial practices, the grant encourages experimentation and creativity, aiming to drive positive structural change in contemporary art. Eligible expenses include artist fees, publication costs, and coalition-building efforts. The next Call for Proposals opens in Fall 2026, with funding of up to $150,000 available for selected projects.

The Critical Needs List by Community Foundation Tampa Bay addresses urgent, unforeseen needs of nonprofits that threaten their ability to serve the community. This innovative program allows nonprofits to submit requests for funding up to $250,000 for critical expenses such as emergency repairs and essential equipment replacement. With a focus on supporting local organizations, the program aims to match funding with community philanthropists, ensuring timely assistance to those in need.