Best Large Grants for Nonprofit Organizations in Arkansas

The Dr. Gary King Sharp Memorial Scholarship, offered by the Central Kentucky Community Foundation, aims to support students with a cumulative GPA of 2.5 or higher. Priority is given to those connected with Hospice services or in the foster care system, and to first-generation college students. This scholarship serves as a vital resource to empower students in their educational pursuits and enhance community life.

The Sonny Greenwood Calzaretta Scholarship, offered by the Pride Foundation, supports LGBTQ+ students from rural communities facing isolation and limited access to resources. Established to honor the legacy of Brian M. Day, this scholarship aims to empower students pursuing post-secondary education while addressing systemic barriers. It prioritizes those demonstrating a commitment to justice and who have experienced challenges such as family rejection or economic hardship. The scholarship is part of a broader initiative to uplift diverse voices within the LGBTQ+ community.

The Periodic Paralysis Grant, offered by the Patient Advocate Foundation, assists individuals diagnosed with periodic paralysis in managing out-of-pocket healthcare costs. Eligible applicants must be in treatment or planning to begin treatment for this rare muscle disease. The fund covers various expenses, including medication copays and insurance premiums, ensuring that patients can afford essential care. With a mission to empower and support patients, this grant plays a crucial role in navigating healthcare challenges.

The Musicians Foundation Grant provides financial assistance to professional musicians in need, covering medical and dental bills, living expenses, and other essential costs during emergencies. Applicants must demonstrate at least five years of professional experience and apply for reasons beyond loss of work. The grants are issued as vendorized checks to ensure immediate support. This program is not designed for COVID-19 assistance or general income support, focusing instead on urgent hardship cases.

The ASSP Foundation Career Development Grant supports individuals in the environmental health and safety field by providing financial assistance for certification and professional development activities. Since its inception in 1990, the foundation has awarded over $6 million in grants and scholarships, aiming to enhance the skills and careers of safety professionals. Preference is given to applicants who have not previously received a grant, promoting a sustainable talent pipeline within the industry.

About Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Who we are and our impact

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Paroxysmal Nocturnal Hemoglobinuria (PNH)

Help with healthcare costs for Paroxysmal Nocturnal Hemoglobinuria (PNH)

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

About the disease

Paroxysmal Nocturnal Hemoglobinuria (PNH), also known as Marchiafava– Micheli syndrome, is a rare disease that is characterized by impaired bone marrow function and destruction of red blood cells. PNH is a rare disease that affects the circulatory system.

The Robert L. Johnson Memorial Research Grant, offered by the Midwest Aquatic Plant Management Society, supports graduate students in aquatic plant management with grants of up to $10,000. This initiative promotes research that advances the management of aquatic ecosystems and fosters educational opportunities. Recipients are required to present their findings at the annual conference, contributing to the society's mission of sustainable aquatic resource management and ecological preservation.

The Measurement and Evaluation Lifetime Achievement Award recognizes a distinguished SHAPE America professional who has significantly impacted measurement and evaluation in health and physical education. This prestigious award highlights the importance of scholarly achievement and the influence of national standards in enhancing educational practices. It aims to honor those who have dedicated their careers to improving the quality of health and physical education, ultimately promoting healthier lifestyles for students across the nation.

The Hyperkalemia Grant, provided by the Patient Advocate Foundation, offers crucial financial assistance to patients struggling with hyperkalemia. This grant covers out-of-pocket healthcare costs, including medication copays and health insurance premiums. Eligible applicants must have a confirmed diagnosis and meet specific income and residency requirements. Since its inception, the foundation has supported millions of patients, ensuring they can access the necessary treatment and resources for their health needs.

The Measurement and Evaluation Honor Award recognizes exceptional contributions by a SHAPE America professional towards the Measurement and Evaluation SIG's mission. This prestigious accolade celebrates those who advance health and physical education practices, inspiring educators to enhance student well-being. Eligibility requires current membership in SHAPE America and the Measurement and Evaluation SIG, ensuring that only dedicated professionals are honored. This award embodies the commitment to fostering excellence in educational environments, ultimately aiming to prepare all children to lead active, healthy lives.

The Luther Halsey Gulick Award, presented by SHAPE America, recognizes individuals with over ten years of membership who have made outstanding contributions to health and physical education. This prestigious honor is awarded annually to a candidate selected for their exemplary leadership and service in the field. Nominations are carefully evaluated based on the candidate's impact on the profession and their ability to inspire future generations to lead healthy, active lives.

The Hypercholesterolemia Grant by the Patient Advocate Foundation offers financial assistance to individuals diagnosed with hypercholesterolemia, helping cover out-of-pocket healthcare costs such as medication copays and insurance premiums. This nonprofit aims to improve patient access to necessary care while supporting over 3.8 million patients since its inception. Eligible applicants must have health insurance and meet specific income requirements to receive assistance in managing their healthcare expenses effectively.

The Howe Foundation, established by Thomas E. Howe in Clark County, Nevada, supports U.S. charitable organizations focused on education, medical advancements, and game hunters associations. Grants are administered by Wells Fargo Bank, with applications reviewed annually in September. Eligible organizations must be 501(c)(3) exempt under the Internal Revenue Code, ensuring support for meaningful community initiatives.

The Metabolic Dysfunction-Associated Steatohepatitis Fund, established by the HealthWell Foundation, aims to alleviate financial burdens for underinsured patients facing chronic illnesses. It provides critical support for expenses related to prescription copays, insurance premiums, and transportation for treatment. With a maximum award of $8,000, the fund ensures that individuals can access necessary healthcare services without financial strain. This initiative emphasizes the commitment to improving health outcomes for those affected by metabolic dysfunction-associated steatohepatitis.

The Mantle Cell Lymphoma Fund, managed by the HealthWell Foundation, provides financial assistance to underinsured patients diagnosed with Mantle Cell Lymphoma. The fund covers prescription drug copays and Medicare Part B premiums, with a maximum award of $8,500. Eligible patients must have insurance that covers their medication and meet specific income guidelines. The foundation aims to reduce financial barriers to essential treatments, ensuring that patients receive necessary care without undue financial strain.

The Hyperoxaluria Fund, managed by the HealthWell Foundation, aims to alleviate financial burdens for underinsured patients suffering from hyperoxaluria, a condition characterized by excessive oxalate in urine. This fund assists with prescription drug copays and insurance premiums, providing vital support for treatments. In 2024 alone, HealthWell allocated over $1.2 billion in grants, ensuring access to essential medications for those in need. The organization is committed to improving healthcare access and reducing disparities for affected individuals.

The ANCA-Assoc Vasculitis and Granulomatosis with Polyangiitis Fund, established by the HealthWell Foundation, aims to reduce financial barriers for underinsured patients suffering from this rare and serious condition. The fund assists with copays, premiums, and out-of-pocket expenses related to treatment, ensuring that affected individuals have access to necessary medications. With over $1.2 billion in grants awarded since 2004, the foundation has helped over 1.1 million patients access critical healthcare services.

Powering Economic Opportunity Fund

Converting America's economic transformation into lasting earnings gains for workers — by backing the employer-side job designs and workplace practices that a durable payer will carry forward.

Across the United States, the modernization of energy systems, physical infrastructure, and advanced manufacturing is creating sustained demand for skilled workers — electricians, welders, energy technicians, construction managers, and industrial specialists — even as the broader labor market has slowed. The Bureau of Labor Statistics projects that energy-related occupations will be among the fastest-growing through 2034, and critical trades face significant shortages as experienced workers retire. 

Geopolitical uncertainty and conflicts only accelerate these trends and the need to focus on energy security. At the same time, AI-driven disruption continues to displace entry-level knowledge roles, creating a strong and underserved candidate pool for durable trade pathways.

Investments are expanding access to skilled trades training, but a critical gap remains between funding workforce programs and achieving lasting employment outcomes. Too many workers complete training without staying in quality jobs, and too few investments address the employer practices that improve retention, advancement and long-term earnings.

As part of our multiyear partnership with Families and Workers Fund, GitLab Foundation is pleased to announce a $4M open call for the Powering Economic Opportunity Fund — flexible grants of up to $500,000 supporting organizations that partner directly with employers, unions and industry to strengthen work-based learning, improve job quality and connect workers to durable, living-wage careers. Round 2 invests in employer-side practice change — the job designs and workplace practices that help workers stay, advance, and build careers — and in the durable financing that sustains those practices after the grant ends.

The Sundance Collab's Cultural Impact Residency, honoring Michael Latt, is a six-month online program supporting early-career, underrepresented storytellers focused on social impact. Running from March to August 2026, it offers mentorship, feedback sessions, and resources to eight selected fellows in screenwriting, directing, and documentary filmmaking. This opportunity is designed for works-in-progress, fostering a supportive creative community to inspire and develop impactful narratives.

The Retail Merchants Association of Tyler Scholarship, administered by the East Texas Communities Foundation, supports graduating seniors planning to major in Business. Eligible students must be from specific Smith County high schools and demonstrate financial need through FASFA. This scholarship, amounting to $1,000, can be used for tuition, fees, and educational supplies. The unique application process matches students with scholarships, ensuring they apply only once and receive consideration for multiple opportunities.

The Council of Independent Colleges

Founded in 1956, the Council of Independent Colleges (CIC) is an association of nonprofit independent colleges and universities, state-based councils, and higher education affiliates that works to support college and university leadership, advance institutional excellence, and enhance public understanding of independent higher education’s contributions to society.

CIC is the major national organization that focuses on providing services to leaders of independent colleges and universities and state-based councils. CIC offers conferences, seminars, publications, and other programs and services that help institutions improve educational quality, administrative and financial performance, student outcomes, and institutional visibility.

NetVUE Vocation across the Academy Grants

​One major purpose of an undergraduate education in the liberal arts is to help students shape a philosophy of life. At the same time, undergraduates today are increasingly preoccupied with postgraduate employment. The purpose of this grant program is to help colleges and universities develop more effective ways to strengthen the link between these two purposes of undergraduate education. It is designed to support institutions in their efforts to expand vocational exploration and discernment programs across the curriculum and co-curricular programs, with the following goals:

• to help students develop more effective links between developing a philosophy of life and preparing for a career;
• to include more faculty and students in the work of vocational exploration and discernment; and, in some cases,
• to build connections with community partners, such as local businesses, nonprofits, and other community organizations.

The NCAA Postgraduate Scholarship for Winter Sports awards up to 126 scholarships of $10,000 annually to outstanding student-athletes who excel both academically and athletically. Eligible candidates are in their final year of NCAA competition and must have a minimum GPA of 3.2. The scholarships are available for men and women in various winter sports and are intended for use in accredited graduate programs, emphasizing the importance of academic achievement and community involvement.

AFL Community Grants aim to empower education, youth, and life advancement through targeted community support. The program is designed for non-profit organizations, focusing on STEM education, youth development, and the LEAP initiative for adult self-sufficiency. With grant applications opening in 2025, AFL Global seeks to make a lasting impact in communities by addressing their greatest needs and fostering growth through education and development initiatives.

The U.S. Hillman Prize for Broadcast Journalism, awarded by the Sidney Hillman Foundation, recognizes outstanding journalism that serves the common good. Open to global journalists, the contest honors work accessible to U.S. audiences, with no entry limits per outlet. Winners receive a $5,000 honorarium and a certificate at a ceremony in New York City. This prestigious award highlights impactful stories across various media platforms, emphasizing the importance of journalism in addressing social issues.

The R. Don Cowan Music & Performing Arts Scholarship, administered by the East Texas Communities Foundation, supports students pursuing studies in music and performing arts, including musical theater and dance. Applicants must be graduating seniors or current college students from Smith County, with no specific financial need requirement. This scholarship is available for one year and allows recipients to major in any subject while continuing their performing arts education.

The Children and Youth with Special Health Care Needs Research Network aims to enhance the lives of children and youth with special health care needs (CYSHCN) and their families. By establishing a robust research infrastructure, the program will generate evidence-based solutions to foster well-being and community engagement. It focuses on identifying effective interventions and measures that can be integrated into essential services and supports, ultimately helping CYSHCN thrive throughout their lives.