Best Operating Grants for Nonprofits in Arkansas

The Tribal Epidemiology Centers initiative aims to support currently unserved areas through a new cohort of TEC sites. Funded by the US Dept. of Health & Human Services: Indian Health Service, this program seeks to enhance public health capacity within tribal communities, ensuring access to essential health services and resources. The initiative underscores a commitment to addressing health disparities and promoting wellness among Native populations.

The Urban Indian Health 4-in-1 Program is designed to enhance the health and well-being of urban Native Americans through targeted initiatives in immunization, health promotion, disease prevention, mental health support, and addressing alcohol and substance abuse issues. Funded by the US Dept. of Health & Human Services, this program aims to improve access to essential health services and foster healthier communities among urban Indian populations.

The Youth Regional Treatment Center Aftercare Program aims to support American Indian and Alaska Native youth in maintaining safety, sobriety, and success post-discharge from Youth Regional Treatment Centers. This initiative enhances culturally relevant, community-based aftercare by fostering care coordination, building partnerships, and addressing barriers to improve youth outcomes.

Tree and Soil Research Fund for Landscape Architecture Grant Program

The TREE Fund Board of Trustees is launching the new Tree and Soil Research Grant, made possible by a permanently restricted endowment fund supporting areas of research of interest to the landscape architecture community with special focus in the area of trees and the soils that support them. Projects are expected to be completed within one to three years, with a maximum award value of $10,000. No project may receive more than one award from this program. 

Award amount:

• up to $10,000 (minimum $5,000) 

The Maternal, Infant, and Early Childhood Home Visiting Program (MIECHV) aims to enhance maternal and child health, promote early childhood development, and support family well-being. By providing voluntary, evidence-based home visiting services to pregnant women and families with young children, the program addresses critical needs in communities. Funded by the US HHS: Health Resources & Services Administration (HRSA), MIECHV empowers families through tailored support and resources, fostering healthier outcomes for mothers and their children.

The Fund for Wild Nature Grant empowers small non-profit organizations in Canada and the U.S. that prioritize the preservation of native species and ecosystems. With a biocentric approach, this grant supports innovative initiatives combating environmental degradation. Organizations must be tax-exempt and can only submit one proposal annually. Grants do not exceed $3,000, ensuring funding is directed to impactful projects addressing ecological issues often overlooked. Join the Fund in investing in the future of wild nature!

The CAFE Group 

We resource leaders, invest in their genius, and bring people together to reimagine what philanthropy can do.

Founded by Liz and Don Thompson, The CAFE Group is a national nonprofit transforming how change is resourced. 

With a focus on education equity, social capital, and philanthropic transformation, we pair catalytic funding, community-rooted leadership development, and cross-sector collaboration to strengthen the people and institutions shaping a more just future. Everything we do is grounded in relationship, because we believe the way resources move matters just as much as where they land.

The 1954 Project Luminary Award

The 1954 Project Luminary Award celebrates transformational education nonprofit leaders dedicated to serving Black students and communities through powerful investments in their organizations' ability to create lasting change.

The Luminary Experience

Each Luminary organization gets more than funding. Through The 1954 Project, leaders gain a community, a platform, and space to grow with tailored support over the course of the three year journey.​

• $1 Million, Unrestricted: Catalytic funding to expand what’s working.
• Leadership Coaching + Capacity Support: Guidance from peers and experts who are committed to helping you build a lasting, impactful organization.
• National Network: Luminaries join a powerful community of innovators, change-makers, and visionaries driving systemic progress to support students and communities across the U.S.

The 1954 Project’s Impact Areas

We focus on three interconnected areas critical to advancing equity:

• Innovation in Teaching and Learning: Create education models that center Black students through culturally affirming approaches that challenge traditional structures and transform how learning happens, ultimately serving all students. 
• Diversity in Education: Build pathways that increase and sustain Black educators and education leaders who transform where and how students learn.
• Pathways to Economic Mobility: Build pathways to wealth, ownership, and economic power for Black students, families, and communities through innovative educational programming.

Our Selection Criteria

We seek out extraordinary applicants who embody our values and vision across three categories:

Leader: We look for leaders whose influence and vision contribute to the collective well-being and advancement of the Black community. These leaders:

• Are Visionary: They demonstrate a strategic and pragmatic mindset, articulating a transformative vision for significant, positive change.
• Show Demonstrated Commitment: They embody steadfast dedication to your cause, inspiring and influencing others, and galvanizing community involvement.
• Are Adaptive: They assertively tackle challenges, turning setbacks into opportunities for innovation, while maintaining humility and thoughtfulness in problem-solving.

Organization: We look for organizations that drive significant change, anchored by a deep love for people and driven by the genius within communities of color. These organizations: 

• Have a Defined Problem: They clearly identify the issue they are addressing and explain in detail how your organization tackles root causes. 
• Take a Strategic Approach: They have clear, measurable, and achievable organizational goals with a well-defined strategy informed by thorough analysis. 
• Show Demonstrated Impact: They have a tested model that has produced positive results, incorporating continuous learning and iteration. 
• Have a Transformation Plan: They present a clear plan for using the $1M award to advance your organization's mission, vision, and long-term goals. 
• Embrace Collaboration: They use collaborate to build partnerships based on trust, love, and common goals. 

Radical Imagination: We seek leaders who challenge and redesign societal norms to build a just and equitable future. They demonstrate:

• Community-Rooted Leadership: They maintain and cultivate genuine community ties, integrating professional expertise and personal commitment to drive visionary, impactful strategies. 
• Long-Term Commitment: They are in it for the long haul, committing to sustained impact across generations and prioritizing long-lasting solutions over short-term gains. 
• Collectivism: They embody the philosophy of "I am because we are," actively engaging in collaborative networks and fostering community-reflective solutions. 

The Pulmonary Hypertension Fund, supported by the Patient Advocate Foundation, offers financial assistance for patients dealing with pulmonary hypertension. This fund covers essential healthcare costs, including medication copays and health insurance premiums. Patients must meet specific eligibility criteria, such as having a confirmed diagnosis and appropriate health insurance. Since 1996, the foundation has empowered millions to navigate healthcare challenges, ensuring they receive the care they need without financial burden.

About Lions Club International FoundationLions Clubs International Foundation (LCIF) provides grants that empower the service of our members. Since its inception in 1968, LCIF has awarded more than US$1.3 billion in grant funding.  Mission :Our mission is to empower Lions clubs, volunteers and partners to improve health and wellbeing, strengthen communities, and support those in need through humanitarian service and grants that impact lives globally, and encourage peace and international understanding. And we fulfill it every day, everywhere we serve.Lions Club International Hunger Grant ProgramHunger Grants focus on strengthening infrastructure and providing essential equipment for Lions’ hunger-relief efforts. These grants empower Lions to support vital initiatives such as school feeding programs, food banks and feeding centers, ensuring that those in need receive the nourishment they require. These grants support infrastructure and equipment acquisition for Lions’ projects focused on alleviating hunger.Grant Examples: 

• Construction or expansion of food banks, feeding centers and food storage facilities.
• Purchase of refrigerators and freezers to store perishable food items.
• Vehicles to transport, collect and deliver food.

The Annual Recurring University Training and Research grant aims to foster the next generation of engineers and scientists by funding research and development at U.S. colleges and universities. This initiative focuses on supporting early-stage research and enhancing opportunities for underrepresented communities, ensuring that students gain essential skills for successful careers in the U.S. workforce and economy. It is a vital step toward inclusive educational advancement and workforce development.

Spencer Educational Foundation Inc

The Spencer Educational Foundation was founded by the Rims Atlanta Chapter in 1979. To this day, Spencer remains the premier organization funding the education of tomorrow's risk management and insurance leaders.

The Spencer Educational Foundation: awards merit-based scholarships and grants to university students pursuing careers in risk management, insurance, and/or actuarial science; provides grants that create experiential learning opportunities both on and off campus; funds the development of risk management and insurance curricula in colleges and universities; supports Risk Managers by creating internship opportunities within the risk management function of their companies; and operates across the United States and Canada. 

Spencer Educational Foundation: General Grants

Spencer’s goal to help build a talent pipeline of Risk Management and Insurance professionals is achieved in part by our collaboration with Risk Management and Insurance educators across the United States and Canada. Since 2010, Spencer has awarded over $4.5 million in General Grants to support over 225 student-centered experiential learning initiatives at universities and RMI non-profit orgs.

Spencer's General Grants Program supports student-centered initiatives that (1) provide experiential learning opportunities for Risk Management & Insurance students and (2) attract new talent to risk and insurance careers. 

American Headache Society

The American Headache Society (AHS) is a professional society of healthcare providers dedicated to the study and treatment of headache and face pain. The Mission of the AHS is to improve the lives of people impacted by migraine and other headache disorders. AHS advocates for those impacted by headache and the headache field, to meet our core objectives. AHS provides educational courses, scientific meetings, a journal, research support, career development opportunities, Special Interest Groups, advocacy training, and a professional community. The AHS strives to meet its objectives while fostering an inclusive sense of belonging and community.

Headache & Migraine Competitive Grant Program

The Headache & Migraine Competitive Grant Program stands at the forefront of advancing headache medicine by funding groundbreaking quality improvement initiatives. This highly competitive grant program, offered through the collaboration between the American Headache Society and Pfizer, supports projects that have the potential to reshape the field by creating widely applicable tools and driving measurable improvements in patient care. 

Migraine & Women's Health

Migraine is a prevalent and debilitating neurological disease that disproportionately affects women, impacting quality of life, productivity, and overall health. Recognizing the need for innovative solutions and enhanced care, Pfizer and the American Headache Society (AHS) are collaborating to offer a new grant opportunity inviting proposals for collaborative quality improvement and research projects focused on migraine and women's health.

The FY 2026 funding opportunity aims to support Indian Tribes and intertribal consortia in implementing approved Nonpoint Source management programs under the Clean Water Act Section 319. This initiative, funded by the EPA, focuses on addressing NPS pollution through best management practices as outlined in Tribal NPS Management Program Plans, ensuring the protection of water resources and promoting sustainability in Tribal lands.

The AACR June L. Biedler Prize for Cancer Journalism

Prize Summary

The AACR June L. Biedler Prize for Cancer Journalism was established by the AACR in 2015 to raise awareness of the critical role that the media play in educating the public about cancer and cancer research.

Funded by a major bequest to the AACR from cancer research pioneer Dr. June L. Biedler, a scientist, mentor, and former member of the AACR Board of Directors, this prize showcases outstanding examples of cancer journalism and recognizes individual professional journalists who have produced accurate, informative, and compelling stories that enhance the public’s understanding of cancer, cancer research, cancer advocacy, or cancer policy.

The prize provides an unrestricted cash award of $5,000 and a commemorative award.

Categories

Each submission may be considered for only one category, as selected by the candidate on the application form.

Applicants may submit in any of the following categories:

Prize Acceptance

Awardees will be able to accept the prize during the AACR Annual Meeting 2027 in Orlando, April 2-7, 2027.

Agnes McCarthy Caregiver Foundation

The Agnes McCarthy Caregiver Foundation is a 501(c)(3) not-for-profit charity that provides hope and relief to caregivers who care for a loved one with mental health conditions.

Caregiver Grant

Family caregiving has become a public health issue that receives inadequate recognition in our country. While it can be rewarding to care for our loved ones, it often comes with significant physical, emotional and financial costs to the caregiver. On average, caregivers spend over 25% of their own income to support their loved one and provide 32 hours a week in unpaid care.

AMCF currently offers a $500 financial relief grant to assist family members with unexpected expenses due to their caregiving role. If you are a family caregiver to someone living with a mood or psychiatric condition like depression, anxiety, PTSD, bipolar, schizophrenia, or other mental health/co-occurring conditions, you are not alone, and we welcome you to apply for a caregiver grant today.

Additional Information

• To ensure our limited funds reach families with the greatest need, grants may require documentation confirming a diagnosed serious mental illness (SMI).  

• The $500 grant is limited to one award per household within a 12-month period.

• Applications are generally reviewed by our Board of Directors, with decisions made within 30 days of receipt.

The OVC FY 2026 grant aims to improve outcomes for child and youth victims of human trafficking by integrating policies at state and Tribal levels. This funding opportunity focuses on developing strategic plans to address the challenges faced by minor victims, enhance coordination among systems like child welfare and juvenile justice, and ensure effective identification and prosecution of traffickers. By fostering multidisciplinary approaches, the program seeks to provide comprehensive support and services to these vulnerable populations.

The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) is set to renew a Notice of Funding Opportunity (NOFO) focused on advancing translational research in maternal and pediatric pharmacology. This initiative aims to enhance precision medicine by developing innovative tools and therapeutics for pregnant and lactating women, infants, and children. The goal is to improve the safety and efficacy of medications while ensuring effective patient-provider communications. Applications are not currently being solicited.

Angel Post Deployment Test Program

Through a collaborative partnership with UNCF, XYZ Corporation has established a scholarship program to help STEM students get on the fast track to a rewarding career. In addition to direct financial support, Intel-sponsored scholarships offer the benefits of exposure to potential job opportunities, networking with fellow scholars, insight to other Intel scholarships, research, training opportunities, and access to Intel mentors offering support on technical, non-technical, cultural, and dissertation-related needs.

The Childhood Asthma in Urban Settings Clinical Research Network (CAUSE) aims to enhance asthma prevention and treatment in economically disadvantaged pediatric populations. Funded by the NIH, CAUSE supports multi-site clinical studies to identify innovative strategies and treatment targets for asthma. Utilizing systems biology, the network seeks to discover specific disease endotypes suitable for new therapeutic approaches, addressing the high burden of asthma in urban settings.

We are living in a time of intensified state violence and mass criminalization. The current political climate has doubled down on surveillance, policing, incarceration, and the criminalization of protest, migration, and mutual aid. For directly impacted communities, the trauma is relentless — and those of us committed to resistance are feeling the weight of outrage fatigue.

But we know: the antidote to outrage fatigue is movement response. The expansion of state violence and mass incarceration often forces organizations to respond quickly to unanticipated events despite lacking the necessary resources or capacity.

The Strategic Opportunities Support (SOS) Fund-CJI’s rapid-response fund-is designed to support bold, strategic, and immediate actions by grassroots organizations on the front lines of resistance. The Fund awards grants up to $7,500 and enables organizations to move quickly and collaboratively in response to emerging threats and seize opportunities to advance justice, healing, and systemic transformation.

The Clinical Data, Safety and Statistical Centers (CDSSC) program, supported by the National Institute of Allergy and Infectious Diseases (NIAID), aims to enhance clinical research through comprehensive support. This includes statistical analysis, protocol development, and oversight of safety monitoring in studies related to asthma, autoimmune diseases, and transplantation. By coordinating these efforts, the program seeks to facilitate impactful research outcomes and improve public health outcomes through informed data-driven decisions.

The Asthma and Allergic Diseases Cooperative Research Centers (AADCRC) program, supported by the National Institute of Allergy and Infectious Diseases (NIAID), aims to enhance research on asthma and related allergic diseases. This initiative fosters multi-center, multidisciplinary research to explore disease mechanisms and treatment responses. By promoting clinical trials and observational studies, the AADCRC seeks to advance understanding and improve interventions for conditions such as asthma and food allergies, ultimately benefiting public health.

About

Macchia Family Foundation

Aims to assist those who cannot assist them selves, or who have attempted to better their own lives and/or the lives of their families but have come up just a little short.

• Assisting children and people in need
• Supporting social, educational and philanthropic programs that better peoples lives
• Providing a helping hand to those who need it

The NIH Research Evaluation and Commercialization Hubs (REACH) program aims to facilitate the translation of biomedical discoveries into marketable products to enhance patient care. By funding five new academic entrepreneurship hubs, NIH will provide essential resources such as funding, mentorship, and expertise in product development. These hubs will address high-priority technologies and foster public-private partnerships, ultimately supporting the goals of federal research initiatives and addressing local health needs in underserved areas.

Healthcare Assistance Grant

The MS Focus Healthcare Assistance Grant assists uninsured individuals with the cost of visiting their MS specialist as well as dental assistance. The grant, which can pay for one visit and one follow-up, is designed to assist those already diagnosed with MS who may need a visit to their treating physician to renew a prescription or handle other important needs. 

Applicants give MS Focus staff authorization to negotiate costs directly with the provider, and the fee is paid directly to the doctor. 

The Frances Parker Rupert Memorial Fund for Music and the Performing Arts provides scholarships to talented students pursuing music or performing arts degrees. Established by the Community Foundation Serving Western Virginia, this fund aims to support high school seniors from specific counties, considering their potential and financial need. Applicants must demonstrate their artistic abilities and articulate how this scholarship will aid their educational goals in a two-page essay.

AMS Organology Study Group Travel Grants

The AMS Organology Study Group Travel Grants program provides travel grants to support AMS Annual Meeting attendance for students and recent graduates with research interests in organology and/or other intersections of music and material culture studies. In addition to supporting attendance at the annual meeting, this program also introduces recipients to a network of scholars working in the field of organology. In 2026, selected recipients will not receive travel grants because the 2026 AMS Annual Meeting is being held online, but will instead receive complimentary registration for the conference. The 2026 AMS Annual Meeting will be held 14–15 November and 19–20 November 2026.

The purpose of the program is to defray costs associated with attending the AMS Annual Meeting and participating in Organology Study Group (OSG) activities. Recipients will be required to attend the Organology Study Group's paper session at the 2026 AMS Annual Meeting.

The Organology Study Group Travel Grants program was established in 2024 with the generous support of the American Musical Instrument Society (AMIS). In addition to complimentary registration for the 2026 AMS Annual Meeting, recipients will receive one year of complimentary membership in the AMIS.