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Best Grants for New Nonprofits in Colorado

Find the perfect Grants for New Nonprofits in Colorado on Instrumentl. 10,000+ Grants for New Nonprofits in Colorado in the United States.

10,000+

Available grants

$2.68B

Total funding

$5K

Median grant

10,000+ grants
$2.68B total
$5K median

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9,638 Results based on applied filters

Rare Organic Acidemias Research (ROAR) Consortium Pilot and Feasibility Grants

Rare Diseases Clinical Research Network (RDCRN)
Federal Government
United States
Up to US $40,000

Our Consortium

ROAR (Rare Organic Acidemias Research) is a multi‑center study that brings together patients, families, clinicians, and researchers to better understand rare organic acidemias such as PA, MMA, GA‑1, IVA, and others. Our goal is to improve lifelong care and future treatment options for the rare disease community.

ROAR works in partnership with patient organizations, clinicians, and research networks to ensure that study findings are shared, accessible, and meaningful. Families play a central role in shaping our questions and informing our direction.

Rare Organic Acidemias Research (ROAR) Consortium Pilot and Feasibility Grants

The overall mission of the ROAR pilot & feasibility grant is to support small projects which advance diagnosis, enhance clinical trial readiness, and improve therapies and outcomes for individuals with organic acidemias. Potential pilot projects may include data-mining of existing data, genotype-phenotype correlations, observational studies, patient-reported outcomes assessments, focus groups with patients and advocacy groups, interventional clinical trials (with prior NIH approval), biomarker studies, ancillary studies to ROAR clinical projects, or other similar projects. Upon completion of funding, we expect that the data generated from ROAR pilot projects will be leveraged for larger grant applications and larger projects within and outside the consortium. Moreover, we expect that the data generated will inform the design of future clinical trials and clinical studies in organic acidemias and ultimately, will impact the lives of individuals with organic acidemias by improving the diagnosis, management, and treatment for these disorders. 

Annual funding of up to $40,000 (total cost, including indirect costs) is available to support one pilot project for a one-year period. The ROAR Consortium intends to fund at least 1 award this cycle starting on October 15, 2026.

Science Rare Diseases

Postdoctoral Diversity Enrichment Grant Program

Burroughs Wellcome Fund
Private
Canada, United States
US $60,000
The Postdoctoral Diversity Enrichment Grant Program, funded by the Burroughs Wellcome Fund, offers $60,000 over three years to support underrepresented postdoctoral fellows in the U.S. and Canada. This initiative aims to enhance their career development through mentorship and networking opportunities. Since its inception in 2013, the program has awarded over 150 fellowships, investing more than $9 million to promote diversity in biomedical research and foster an inclusive scientific community.
Diversity, Equity & Inclusion Science Biology +1 more

Career Awards for Medical Scientists

Burroughs Wellcome Fund
Private
Canada, United States
US $700,000
The Career Awards for Medical Scientists (CAMS), established by the Burroughs Wellcome Fund, offers $700,000 over five years to support early career physician scientists transitioning to independence in academic biomedical research. This highly competitive program aims to enhance research innovation and public service by fostering a diverse scientific workforce. Proposals in basic biomedical, disease-oriented, or translational research, particularly those incorporating artificial intelligence or addressing climate change and human health, are encouraged.
Medical Education & Professional Training Science Health & Medicine +1 more

The NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC) Data Coordinating Center

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC) Data Coordinating Center aims to enhance understanding of inflammatory bowel disease (IBD) by coordinating extensive genetic research. By leveraging diverse patient cohorts and advanced data science techniques, the center seeks to identify genetic risk factors, develop predictive biomarkers, and improve IBD patient management. This initiative will facilitate collaboration among various research centers and ensure efficient data collection and sharing to foster advancements in precision medicine for IBD.
Digestive System Health & Diseases Data Science & Digital Information Systems

May Family Foundation Community Outreach Grant

May Family Foundation
Private
Dane County, Wisconsin, Douglas County, Nebraska +10 more
Up to US $50,000

May Family Foundation

Eleanor Jean May established the May Family Foundation in 2000, as a gesture of gratitude to the communities that shaped her life. The May Family Foundation is dedicated to identifying programs that strongly resonate with our mission and values as we work together to empower and uplift lives within our communities.

Our foundation provides resources and opportunities that empower young individuals to thrive and reach their full potential. Our goal is to create a brighter future for under-resourced youth in our local communities.

May Family Foundation Community Outreach Grant

Our foundation strives to be engaged in our local communities beyond grant funding. We support select programs that align with our goals and form a connection through potential volunteering opportunities, site visits, and recognition of successes.

We welcome grant applications for financial support in community outreach:

  • Programs that provide professional services to under-resourced families who may not otherwise have access.
  • We support programs that help to identify existing problems or challenges in our local communities and provide the means and resources to solve them.
Community Services Family Services Poverty Alleviation & Services

Strategic Initiatives Grants

State Justice Institute
Private
United States
Unspecified amount
The Strategic Initiatives Grants (SIG) program, managed by the State Justice Institute (SJI), offers flexible funding to tackle pressing national court issues. This innovative initiative encourages collaboration between SJI and its grantees to develop effective solutions for state courts across the U.S. Applicants are urged to reach out to SJI for guidance on their concept papers, ensuring a tailored approach to addressing critical judicial challenges.
Law Criminal Justice System Reform

NIDA Avenir Program: Fundamental Mechanistic Research in Addiction Science

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $375,000
The NIDA Avenir Program aims to cultivate innovative leaders in addiction science by funding exceptional early stage investigators (ESIs) embarking on pioneering research. Launched in 2015, this initiative encourages high-risk, high-reward mechanistic studies related to Substance Use Disorders (SUDs) across diverse scientific domains. Applications from new investigators and those outside addiction research are welcomed, fostering interdisciplinary approaches that enhance understanding of SUD mechanisms. The program supports ESIs who may lack preliminary data but demonstrate potential for impactful contributions.
Genetics & Genomics Addiction & Substance Use Disorders Emerging Technology Development

Wehrli Custom Fabrication Scholarship Fund

Dekalb County Community Foundation
Private
United States
Unspecified amount

Scholarship amounts vary depending on the scholarship applied for. Applicants are encouraged to apply for as many awards as they are eligible to increase the likelihood of receiving one or more awards.

Scholarships can be used for cost of attendance, direct education expenses, including tuition, books, and/or other school-related fees.

If you receive an award, be sure to complete your scholarship acceptance form (online portal). Scholarship awards are paid directly to the academic institution by the end of August.

Wehrli Custom Fabrication Scholarship Fund

The Wehrli Custom Fabrication company created the scholarship to aid students interested in pursuing a career in the trades. The Fund supports two annual scholarships. The first is for a student attending a trade school or 2-year college, and the second benefits a student attending a 4-year college or university. Eligible areas of study include welding, machine tooling, auto mechanics, auto body, business management, and mechanical, industrial, manufacturing, or agricultural engineering.

Education - Higher Education Vocational & Trade Education

Nursing Scholarship Grants

Deaconess Foundation
Private
United States
Up to US $15,000
The Deaconess Foundation offers Nursing Scholarship Grants aimed at supporting local students pursuing nursing degrees with demonstrated financial need. This program reflects the foundation's mission to enhance community health in Eastern Missouri and Southern Illinois. Grants are administered in partnership with the Scholarship Foundation of St. Louis and the St. Louis American Foundation. Eligible students must be working towards an accredited nursing degree and demonstrate significant financial need, among other criteria.
Nursing

NFPF: Matching Grants

National Film Preservation Foundation
Private
United States
US $20,001 - US $75,000
The National Film Preservation Foundation (NFPF) offers Matching Grants to support the preservation of significant American films. Nonprofit and public institutions can apply for projects involving complex preservation efforts, with cash stipends ranging from $20,001 to $75,000. Grants require a matching contribution of one-fifth of the project costs. Since its inception, the NFPF has aided numerous organizations in preserving culturally important films, ensuring their accessibility for future generations.
Film

DoW Traumatic Brain Injury and Psychological Health, Translational Research Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
US $1,000,000 - US $2,000,000
The DoW Traumatic Brain Injury and Psychological Health Translational Research Award aims to transform scientific discoveries into clinical applications. This program encourages innovative research approaches and requires preliminary data. It prohibits basic research and clinical trials, emphasizing the need for relevant animal models or community-based participatory research for human subjects. Funding supports two research levels, refining ideas into tangible products or evaluating them for clinical trials, with options for early-career investigator partnerships.
Brain Injuries

MIND (Maximizing Innovation in Neuroscience Discovery) Prize

Pershing Square Sohn Cancer Research Alliance (PSSCRA)
Association/Society
United States
Up to US $750,000

MIND (Maximizing Innovation in Neuroscience Discovery) Prize

The Pershing Square Foundation’s (PSF) brain initiative funds cutting-edge research that revolutionizes our ability to predict, prevent, and treat neurodegenerative diseases (NDDs). Advancing our fundamental understanding of the brain and cognition to ultimately combat neurodegeneration and related diseases is a goal of increasing urgency. Breakthroughs in basic scientific and translational research will yield critical tools for and knowledge of NDDs, including Alzheimer’s Disease and Dementia, which affect millions of people worldwide.

The MIND (Maximizing Innovation in Neuroscience Discovery) Prize supports and empowers early-to-mid-career investigators to rethink conventional paradigms around NDDs. Modeled after the Pershing Square Sohn Prize for Young Investigators in Cancer Research, the MIND Prize catalyzes interdisciplinary approaches and facilitate collaborations across academic departments and institutions. It fuels the groundbreaking research that will accelerate our understanding of NDDs at every level.

Projects may range from the invention of novel tools, techniques, and technologies for mapping and analyzing the brain to bold approaches that demonstrate extraordinary therapeutic potential. Research domains may include—but are not limited to—neurobiology, brain imaging and mapping, machine learning, drug delivery, and synthetic biology. Applicants are encouraged to propose bold, hypothesis-driven, high-risk, high-reward research with the potential for transformative impact. Tool and technology development are permitted when they support the testing of a clearly defined biological hypothesis. Screening may be part of the proposed work, but should not be the sole focus. Clinical components are permitted, but proposals should not center on clinical trials or medical device testing in humans.

MIND Prize winners each receive $250,000/year for three years, and they become part of a unique network of researchers associated with PSF. Generally, at least six prizes will be awarded annually. Benefits include:

  • Facilitated partnerships with like-minded researchers within and across institutions
  • Networking programs such as collaborations and discussions with industry mentors, introductions to philanthropic and for-profit investors in the business community, special industry networking and entrepreneurship events, and more
  • An annual retreat
  • Opportunities to present at conferences and events (hosted by PSF and other organizations)
Neuroscience

Nsf Stem K 12

National Science Foundation (NSF)
Federal Government
United States
US $25,000 - US $750,000
The NSF STEM K-12 program supports transformative research to enhance STEM education across various settings. Focusing on innovative projects, it aims to improve teaching and learning through the integration of emerging technologies, including AI. Proposals may address any STEM field, fostering collaboration between research and educational practice. By generating new knowledge and tools, this initiative seeks to strengthen the U.S. position in global STEM innovation and improve educational outcomes for learners of all ages.
Education - K through 12 STEM / STEAM Education

Encantado Foundation Impact Grant

Encantado Sandia Foundation
Private
United States
US $50,000 - US $200,000
The Encantado Foundation Impact Grant aims to enhance the development of hire-ready candidates in STEM fields across Northern and Central New Mexico. This initiative focuses on empowering underrepresented communities by providing resources to nonprofit organizations that successfully create job opportunities, offer professional development programs, and engage with diverse populations. By supporting impactful projects in cyber security, application development, and IT operations, the grant seeks to reshape the local workforce landscape.
STEM / STEAM Education Apprenticeship & Internship Programs

NCI Research Specialist Award for Core and Laboratory-based Scientists (R50 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NCI Research Specialist Award (R50) supports non-tenure track scientists in cancer research who provide essential contributions within laboratories and core facilities. This award aims to enhance research careers for skilled scientists who do not seek independent investigator funding. Eligible candidates must possess an advanced degree, have at least two years of contribution to NCI-funded research, and dedicate a significant portion of their time to this work. The R50 offers salary support and travel funds to recognize and stabilize these vital roles in cancer research.
Cancer / Oncology

NCI Research Specialist (Clinician Scientist) Award (R50 Clinical Trial Not Allowed) (362277)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NCI Research Specialist Award (R50) supports clinician scientists involved in NCI-funded clinical trials. This funding opportunity encourages the development of stable research careers by providing salary support and autonomy, allowing clinician scientists to contribute to national clinical trial development and implementation. They play a critical role in sustaining the NCI clinical trials network without serving as principal investigators. This award aims to ensure continuity in cancer research careers.
Cancer / Oncology

DoW Traumatic Brain Injury and Psychological Health, Health Services Research Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $4,000,000
The FY26 Traumatic Brain Injury and Psychological Health Research Program (TBIPHRP) aims to support impactful health services research that connects research, practice, and policy. It emphasizes building real-world evidence for interventions and clinical guidelines tailored to specific populations. Key features include requirements for clinical trials, preliminary data, and community-based participatory research approaches. The program also offers an Early-Career Investigator Partnering Option to foster collaboration between seasoned and emerging researchers.
Brain Injuries

DoW Traumatic Brain Injury and Psychological Health, Clinical Trial Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
US $2,100,000 - US $4,100,000
The FY26 Traumatic Brain Injury and Psychological Health Research Program's Clinical Trial Award aims to fund impactful clinical trials that address psychological health issues and traumatic brain injury (TBI). This award supports a variety of interventions, requires preliminary data, and mandates community-based participatory research approaches. It offers two research levels: one for pilot studies and early trials, and another for larger, advanced trials assessing effectiveness in relevant populations.
Brain Injuries

NFPF: Basic Preservation Grants

National Film Preservation Foundation
Private
United States
US $1,000 - US $20,000
The National Film Preservation Foundation offers Basic Preservation Grants to nonprofit and public institutions for preserving culturally significant American films. Since 1998, they have provided resources to 337 organizations across the U.S. Grants range from $1,000 to $20,000, facilitating the creation of new film preservation elements and public access copies. With an annual award of 30 to 40 grants, this initiative plays a crucial role in ensuring the survival of films that are at risk of being lost.
Film

Youth Programming Grant

Native American Agriculture Fund
Private
United States, United States Minor Outlying Islands
Unspecified amount
The Youth Programming Grant, offered by the Native American Agriculture Fund (NAAF), aims to support Native American farmers and ranchers through various projects. This grant focuses on providing essential business assistance, agricultural education, and advocacy services. By funding diverse initiatives, the NAAF seeks to promote the ongoing involvement of Native communities in agriculture, ensuring their sustainable growth and development within the sector.
Agricultural Education

World Childhood Foundation - Propose a Program

World Childhood Foundation Inc
Private
United States
Unspecified amount
The World Childhood Foundation aims to eradicate child sexual abuse and exploitation through innovative programs. Organizations eligible for funding must be based in the U.S. and focus on child safety, supportive environments, and responses to abuse. The grant does not support emergency relief, orphanages, or established program costs. Interested applicants should start the process 1-2 months prior to the deadline to ensure they can fulfill the necessary requirements, including a site visit.
Child Welfare Services Crime Victim Services

Oneita J. Waltenberger Scholarship Fund

Dekalb County Community Foundation
Private
United States
Unspecified amount

Scholarship amounts vary depending on the scholarship applied for. Applicants are encouraged to apply for as many awards as they are eligible to increase the likelihood of receiving one or more awards.

Scholarships can be used for cost of attendance, direct education expenses, including tuition, books, and/or other school-related fees.

If you receive an award, be sure to complete your scholarship acceptance form (online portal). Scholarship awards are paid directly to the academic institution by the end of August.

Oneita J. Waltenberger Scholarship Fund

Established in 2015, this scholarship provides support to current or former residents of DeKalb County, IL, who are pursuing undergraduate or post-graduate education in the healthcare field. Current high school students, including high school seniors, do not qualify.

Education - Higher Education Medical Education & Professional Training

Friends of Carl Sandburg Donald E. Hubbs Scholarship Fund

Community Foundation of Henderson County
Private
United States
US $2,000
The Friends of Carl Sandburg Donald E. Hubbs Scholarship Fund, managed by the Community Foundation of Henderson County, aims to support Henderson County residents pursuing college degrees in Conservation, Animal Science, or Parks and Recreation. This fund prioritizes students specializing in American Literature but is open to those not necessarily at the top academically or financially. Established in 1982, the foundation has a strong history of facilitating community philanthropy.
Education - Higher Education Academic Scholarship Programs

American Fellowships - American Short-Term Research Publication Grants

American Association of University Women (AAUW)
Association/Society
United States
US $8,000
The American Fellowships - American Short-Term Research Publication Grants support women in academia by funding the preparation of research manuscripts for publication. Established by the AAUW in 1888, these grants aim to enhance gender equity in higher education, particularly for women pursuing careers in STEM fields. Eligible applicants must hold advanced degrees and demonstrate significant contributions to their fields. This initiative highlights AAUW's long-standing commitment to empowering women through education and research.
Writing & Literature Gender Studies

Animal Food Regulatory Program Standards Implementation Development and Maintenance, with Mutual Reliance Initiatives Clinical Trials Not Allowed

US Department of Health & Human Services: Food and Drug Administration (FDA)
Federal Government
United States
Up to US $300,000
The Animal Food Regulatory Program Standards Implementation Development and Maintenance initiative aims to enhance the national animal food safety system. This funding opportunity supports state regulatory programs in achieving and sustaining the Animal Food Regulatory Program Standards (AFRPS) within five years. By fostering collaboration with the FDA and standardizing regulatory processes, this initiative seeks to improve food safety, promote compliance, and mitigate foodborne illnesses, ultimately creating a more integrated food safety framework.
Animal Food & Drug Safety

Grants for New Nonprofits in Colorado Highlights

Looking for grants for new nonprofits in Colorado?


Read more about each grant below or start your 14-day free trial to see all grants for new nonprofits in Colorado recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Grants for New Nonprofits in Colorado

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Grants for New Nonprofits in Colorado grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

77 Grants for New Nonprofits in Colorado over $25K in average grant size

62 Grants for New Nonprofits in Colorado over $50K in average grant size

43 Grants for New Nonprofits in Colorado supporting general operating expenses

200+ Grants for New Nonprofits in Colorado supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

800+ Grants on Instrumentl focused on Senior Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for grants for New Nonprofits in Colorado?

Most grants are due in the first quarter.

Q1
29.8%
Q2
23.3%
Q3
25.7%
Q4
21.2%

Typical Funding Amounts

What's the typical grant amount funded for Grants for New Nonprofits in Colorado?

Grants are most commonly $15,000.

$500 $500 Min.
$15,000 $15 K Median
$333,350 $333.4 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for Colorado?

Grants are most commonly $104,627.

$104,627

Total Number of Grants

What's the total number of grants in Grants for New Nonprofits in Colorado year over year?

In 2024, funders in Colorado awarded a total of 62,070 grants.

2022 58,261

2023 56,542

2024 62,070

Top Grant Focus Areas

Among all the Grants for New Nonprofits in Colorado given out in Colorado, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Grants for New Nonprofits in Colorado changing over time?

Funding has increased by 26.35%.

2022 $5,306,649,967

2023 $5,130,283,753
-3.32%

2024 $6,482,367,642
26.35%

Colorado Counties That Receive the Most Funding

How does grant funding vary by county?

El Paso County, Denver County, and Boulder County receive the most funding.

County Total Grant Funding in 2024
El Paso County $1,985,707,956
Denver County $1,884,804,542
Boulder County $1,684,238,774
Jefferson County $695,695,439
Arapahoe County $654,949,684