Best Unrestricted Grants for Nonprofits in Colorado

The NIMH Career Transition Award (K22) supports tenure-track intramural investigators at NIMH in their transition to independent research faculty positions. This program aims to foster innovative research in mental health, encouraging applicants with a strong record of research excellence. Key deadlines for applications vary, including those for standard and renewal submissions, emphasizing the importance of timely applications to secure funding and advance mental health research initiatives.

The William H. Scheide Prize, established in 1990 by the American Bach Society, honors exceptional publications on Bach or related figures by early-career scholars in North America. Awarded biennially with a prize of $1,000, it recognizes works published within the last two years. Nominations are open to all Society members, and self-nominations are encouraged. Each winner also receives a two-year membership in the American Bach Society.

The Open Ocean Research Grant Program, funded by Global Fishing Watch Inc, aims to enhance ocean governance through data sharing on human activity at sea. It invites researchers to improve technologies for better governance, offering up to $10,000 for individuals and $20,000 for small groups. This initiative strengthens the community of practice and optimizes Global Fishing Watch datasets to maximize their impact on ocean conservation efforts.

The Peer Education Grant, offered by the Organization for Autism Research, aims to enhance autism acceptance among children by providing educational resources and funding for initiatives. Grants of up to $10,000 support school-wide projects, with smaller grants available for other activities. Eligible applicants include educators and community organization leaders focused on autism awareness, particularly in low-income areas. This initiative fosters inclusive relationships and understanding between children and their autistic peers.

The William H. Scheide Research Grants, established by the American Bach Society in 1990, support research on Johann Sebastian Bach and his contemporaries. With stipends ranging from $500 to $4,000, these grants are awarded annually and may cover travel and primary source reproduction costs. Preference is given to Ph.D. candidates and junior faculty, but senior faculty are also encouraged to apply. Each recipient receives a one-year membership in the Society, fostering further engagement with Bach's music.

The Trans Justice Funding Project (TJFP) provides grants to grassroots trans-led organizations in the U.S. and territories, focusing on those with budgets under $250,000. TJFP supports initiatives that address varying needs within trans communities, including health, legal aid, and mutual aid projects. The organization prioritizes groups led by trans people of color and emphasizes the importance of centering marginalized voices in the fight for trans justice.

The Path to a Cure (PTAC) - Postdoc-to-Faculty Transition Award by the Cystic Fibrosis Foundation supports postdoctoral fellows in advancing their research careers in cystic fibrosis. This program offers up to five years of funding, including 3 years for research training and 2 years for transitioning to an independent faculty position, with a maximum support of $110,000 per year. It aims to foster innovative research that develops new therapies for cystic fibrosis.

The Arthritis National Research Foundation (ANRF) offers grants for research focused on Psoriatic Arthritis (PsA). With funding of up to $125,000 over two years, the ANRF encourages innovative projects that reveal the underlying mechanisms of PsA. Eligibility includes M.D. or Ph.D. qualifications and affiliation with a U.S. nonprofit research institution. Preference is given to senior post-doctoral researchers transitioning to independent status and new assistant professors. Applications without a Co-PI or those who have previously received ANRF funding will not be accepted.

The Rapid Outcomes from Agricultural Research (ROAR) Grant Program, managed by the Foundation for Food and Agriculture Research (FFAR), provides urgent funding for research addressing unexpected threats to the food supply. This program supports diverse projects related to pest and pathogen outbreaks, facilitating quicker responses than traditional funding avenues. With grants up to $150,000, ROAR aims to enhance agricultural resilience by fostering collaborations among researchers, institutions, and organizations to combat emerging challenges in the food and agriculture sector.

The Cystic Fibrosis Foundation offers the Path to a Cure (PTAC) Postdoctoral Research Fellowship Award to support innovative research training in cystic fibrosis (CF). Aimed at enhancing scientific knowledge and facilitating the transition to independent careers, this program funds projects targeting the development of new therapies for CFTR variants. Awards can reach up to $75,000 in the first year and $76,000 in the second year, fostering foundational research that could lead to breakthroughs in CF treatment.

Community Foundation of Henderson County

Community Foundation of Henderson County was incorporated in 1982 by a group of fourteen dedicated and compassionate local leaders with the immediate need to manage two funds - the William C. Armstrong Scholarship Fund and the Charlie Renfrow Scholarship Fund, in addition to providing a permanent vehicle for citizens to give back to their community.

Our Mission is to help people who care make lasting contributions to causes that matter. The Community Foundation of Henderson County is a highly visible, philanthropic leader directed by an engaged and committed board, staffed by qualified employees, empowering donors at all levels to invest in professionally managed charitable funds that address community needs.

Arthur and Lois Jean Stuenkel Scholarship

This scholarship provides financial support to a graduating senior seeking to further his or her education beyond high school. The recipient must be in the top 25% of his or her graduating class and demonstrate financial need. This scholarship is for a worthy student who has participated in sports or extracurricular activities. 

The scholarship is renewable.

The Cancer Health Equity Research Centers (CHERCs) initiative by the American Cancer Society aims to address health disparities by supporting research focused on social determinants affecting cancer care. This program encourages innovative projects that engage communities, enhance access, and improve outcomes across diverse populations. By fostering collaborations and promoting multidisciplinary approaches, CHERCs strive to create equitable cancer prevention and treatment solutions, ensuring that all individuals have fair opportunities for cancer care and survivorship.

The Pizza Hut Foundation is offering scholarships for students demonstrating financial need and community leadership. Eligible applicants must be U.S. residents aged 17-26, enrolled in accredited post-secondary education for Spring 2026, and maintain a minimum GPA of 2.5. Scholarship amounts range from $500 to $5,000, with distribution to be made in Spring 2026. The application period runs from July 8 to September 5, 2025, with notifications for recipients by November 17, 2025.

American College Of Sports Medicine Foundation Inc

ACSM is the largest sports medicine and exercise science organization in the world, with nearly 50,000 international, national and regional members and certified fitness professionals.

Our Mission: To educate and empower professionals to advance the science and practice of health and human performance.

GSSI Pathways in Sports Science Award | Graduate Student Research & Mentorship Award

GSSI celebrates the passion, resilience, and academic excellence of first-generation college students pursuing graduate degrees in exercise physiology, sports science, kinesiology, and/or sports nutrition. Designed to empower emerging leaders in the field, the award recognizes individuals who are breaking new ground, not only in their families but in the science of human performance.

In addition to research funding, to help promote professional development, award winners will receive one year of 1:1 mentorship from a GSSI scientist. Award winners will also receive complementary registration to ACSM’s 2027 Annual Meeting in Indianapolis, IN.

ACSM requires award winners to:   

• Submit official transcripts if selected as an award winner, 
• Attend the 2027 ACSM Annual Meeting in Indianapolis, IN. 
• Present funded research at a future ACSM Annual Meeting, and   
• Send ACSM a copy of any publications or presentations related to the funded research. 

The TTP Bridge Program aims to enhance the safety and accessibility of bridges in Tribal communities, addressing the urgent need for infrastructure improvements. With aging bridges affecting economic development and children's transportation, this program allows federally recognized Indian Tribes to apply for funding for planning, construction, and rehabilitation of bridges. By focusing on TTP bridges in poor condition, the initiative seeks to strengthen economic foundations and ensure better connectivity with markets, benefiting both families and communities.

Community Foundation of Henderson County

Community Foundation of Henderson County was incorporated in 1982 by a group of fourteen dedicated and compassionate local leaders with the immediate need to manage two funds - the William C. Armstrong Scholarship Fund and the Charlie Renfrow Scholarship Fund, in addition to providing a permanent vehicle for citizens to give back to their community.

Our Mission is to help people who care make lasting contributions to causes that matter. The Community Foundation of Henderson County is a highly visible, philanthropic leader directed by an engaged and committed board, staffed by qualified employees, empowering donors at all levels to invest in professionally managed charitable funds that address community needs.

Bryce A. Malsbary (BAM) Scholarship

The purpose of the Fund is to provide a scholarship for a person seeking higher education at an accredited institution, including but not limited to: vocational, technical, trade, college, or university levels of education. Assistance is for a resident of Henderson County or Polk County, North Carolina, leading to a degree. Candidate must show financial need, GPA 3.0 or higher, and have community service, work, or school activities. Student must be a legal resident of North Carolina.

The Karl A. Bickel and Madira Bickel Journalistic Scholarship Fund Grant supports journalism students at accredited colleges and universities. Established under Karl A. Bickel's Last Will and Testament, it awards approximately $40,000 annually. Eligible organizations must have journalism programs and qualify as 501(c)(3) exempt entities. While there are no geographical restrictions, preference is given to institutions in Florida. The fund is administered by Wells Fargo Bank, ensuring that deserving students receive necessary financial support.

The grant mechanism will focus on furthering the development of strategies towards improving the outcomes of Small Cell Lung Cancer (SCLC) patients through patient advocacy. Work supported through this mechanism will address important areas of need across the entire care continuum and have the immediate potential to increase research efforts, quality of life and survivorship. The overarching theme of the proposals should be centered around using patient advocacy as a tool to develop strategies toward improving outcomes for patients with SCLC. We will encourage applications on a wide variety of topics related to SCLC, including but not limited to the following:

• Patient-Centric Care Models
  • Develop and implement care models that prioritize patient needs and preferences, integrating innovative approaches from diagnosis through survivorship
• Advanced Screening and Diagnostic Technologies
  • Create comprehensive survivorship care plans addressing long-term healthcare needs, focusing on follow-up care, monitoring for recurrence, and managing chronic side effects

• Access and Equity
  • Investigate barriers to accessing quality care, clinical trials, screening and biomarker testing for SCLC patients and purpose solutions to ensure equitable healthcare delivery for diverse populations

• Technology Integration
  • Explore the use of digital health tools and technologies to facilitate better patient-provider interactions, personalized care, and continuous monitoring during the care continuum
• Patient Feedback Mechanisms
  • Establish robust feedback systems to gather patient insights and experiences and use this data to inform continuous improvements in care delivery, diagnostic technologies, treatment approaches, clinical protocols and accessible repositories to facilitate broad research collaboration

The 2026 Strategies Using Patient Advocacy to Improve Outcomes in Small Cell Lung Cancer will grant a minimum of one award of $250,000 for a period two years ($125,000 per year).

The Anna B. Glauser Trust Grants provide financial support to organizations aiding physically handicapped individuals, particularly blind residents in Delaware County, PA. Established in memory of Willis K. Glauser, the trust awards 1-2 grants annually, ranging from $2,500 to $5,000. Eligible organizations must be 501(c)(3) certified, while funding for salaries is typically excluded. This initiative reflects Anna Glauser's lifelong commitment to assisting the visually impaired community.

The Vibrant Communities: Convenient Neighborhoods Grant Opportunity, provided by the Colorado Gives Foundation, aims to enhance access to community spaces in Jefferson County. This initiative supports nonprofits working towards improved public transportation, increased outdoor green spaces, and the establishment of integrated community hubs. By ensuring easy access to parks, farmers markets, and recreation centers, the grant fosters overall health and wellbeing for all residents. Organizations must be 501(c)(3) nonprofits committed to serving the Jeffco community.

The Economic Freedom: Workforce Development Grant Opportunity, offered by the Colorado Gives Foundation, aims to enhance job market adaptability for Jefferson County residents. This grant supports nonprofits that provide solutions leading to higher wages, promote educational transparency, and bridge skill gaps in education. Organizations eligible must be 501(c)(3) nonprofits or government entities focused on serving Jeffco, ensuring that their initiatives directly impact the community's workforce development.

The Patient Directed Investigation Grant by the Dermatology Foundation supports translational studies aimed at improving patient care in various dermatological fields. With an annual funding of $25,000, it fosters the career development of early-stage clinical investigators. Eligible applicants include those who have completed U.S. dermatology residency training and are not funded by other sources. The grant encourages diverse applicants, particularly from minority backgrounds, to contribute to vital health issues affecting underserved populations.

The American Heart Association (AHA) is launching the RFP for a Strategically Focused Research Network (SFRN) aimed at enhancing the early detection and delaying the progression of valvular heart disease. This initiative seeks collaborative proposals from researchers to address critical questions and advance understanding in this field. With a maximum budget of $4.4 million and a duration of four years, the AHA plans to award at least three grants based on scientific merit and alignment with its mission.

The Anna Lalor Burdick Program supports initiatives that enhance women's access to reproductive health care, contraception, and pregnancy termination. It prioritizes funding programs that provide comprehensive sexual and reproductive health education, particularly for disadvantaged women. The program seeks innovative approaches, clear goals, and sustainable models, while emphasizing advocacy efforts. Organizations dedicated to reproductive rights in restrictive environments are encouraged to apply, as the foundation aims to empower women through informed choices.

The Classics for Kids Matching Grant Program, established by the Classics for Kids Foundation, aims to enhance music education for at-risk and rural youth by providing matching grants for fine stringed instruments. Since 1998, over $2 million has been allocated to support more than 300 programs across all 50 states. Schools and non-profits demonstrating need and commitment are encouraged to apply, fostering lifelong benefits of music participation and education.

The Jennifer Easton Community Spirit Award honors Native artists who have dedicated their lives to sharing cultural knowledge and ancestral gifts. With a grant of $50,000, this award supports artists deeply rooted in their communities, fostering healing and resilience. Nominations are open for practicing artists across various mediums, including music, dance, and storytelling, ensuring the continuation of Indigenous traditions and the enrichment of Native culture.

The Native Performing Arts Fellowship (NPA) supports Native artists in enhancing their craft through grants of up to $10,000. This fellowship prioritizes personal artistic development over project-based funding, encouraging applicants to focus on growth through classes, workshops, and professional mentorship. Eligible candidates must be U.S.-based, 18 years or older, and enrolled members of recognized tribes. The program emphasizes Indigenous values in performing arts, fostering resilience and cultural expression.