Best Foundation Grants for Nonprofits in Connecticut

The Life Comes From It Grant, funded by the Tides Foundation, supports grassroots initiatives focused on restorative, transformative, and indigenous justice. It prioritizes projects led by communities of color, emphasizing alternatives to incarceration and community-led solutions. Applicants must be 501c3 organizations based in the United States. This grant fosters a collaborative approach to healing and justice, aiming to shift power dynamics and promote inclusive practices across generations.

The Patient-Centered Outcomes Research Institute (PCORI) will announce the Phased Large Awards for Comparative Effectiveness Research on December 2, 2025. This funding aims to support high-quality, patient-centered comparative clinical effectiveness research projects. The initiative encourages applicants to engage with patients and stakeholders to address critical healthcare dilemmas and improve decision-making. Projects should compare established clinical alternatives with evidence of efficacy, targeting vital health issues across diverse populations.

The MIND Prize, funded by The Pershing Square Foundation, supports innovative research to combat neurodegenerative diseases like Alzheimer's. It empowers early-to-mid-career investigators to explore unconventional approaches and fosters collaboration across disciplines. Each winner receives $250,000 annually for three years, promoting advancements in neuroscience and creating a unique network for researchers. The initiative aims to enhance our understanding of brain health and tackle pressing societal challenges.

The Harry Kramer Memorial Fund Grant supports U.S. charitable organizations that assist individuals and institutions in Israel, focusing on welfare, healthcare for the sick and aged, and education in South Florida. Founded by Harry A. Kramer, a successful entrepreneur and veteran, the fund reflects his deep commitment to charitable causes. Organizations must qualify under Section 501(c)(3) and meet specific eligibility criteria to apply for funding, ensuring that aid reaches those in need.

The Metropolitan Water District of Southern California's Innovative Conservation Program (ICP) has funded innovative water savings projects since 2001, with $250,000 available biannually. The program aims to evaluate and demonstrate the reliability of new water-saving technologies. Nearly 400 proposals have sought $36 million in funding. The ICP, supported by multiple agencies, encourages projects that can benefit Southern California's water efficiency, inviting proposals from outside its service area to enhance regional water management.

The BJA FY 2026 Second Chance Act Community-based Reentry Program aims to support community organizations and tribal governments in providing essential mentoring and transitional services for individuals returning from correctional facilities. This initiative targets those assessed as moderate to high risk for recidivism, addressing their needs both pre-and post-release. By fostering successful reintegration into society, the program contributes to public safety and reduces recidivism rates, aligning with the mission of the U.S. Department of Justice.

Daviess County Community Foundation

The Community Foundation is a charitable resource devoted to our local community. We help people make meaningful gifts that improve life in Daviess County, Indiana today and for generations to come.

The Community Foundation can help you...

• Make a difference where it matters
• Invest in the future of the community you love
• Create greater good together

John R. Chapman Scholarship

Annual, renewable scholarship established by the John R. Chapman Trust Fund to provide a renewable scholarship to graduating seniors of Washington Community or North Daviess high schools.

Award Amount

• $4,170

The National Institutes of Health is launching a funding opportunity to explore the mechanisms of skin injuries caused by toxic chemicals. This initiative aims to understand the common pathways of injury from various harmful substances, facilitating the discovery of therapeutic targets. Researchers are encouraged to collaborate and apply their expertise in cutaneous wound healing. The goal is to develop broad-spectrum medical countermeasures for mass casualty events involving toxic exposures, enhancing public health safety.

The Elizabeth Pastor Ashland University Music Education Scholarship supports music students at Ashland University, honoring the legacy of Elizabeth Pastor, a renowned pianist and educator. This scholarship aims to assist students pursuing a music-related career, reflecting Pastor's belief in the transformative power of art. Established through her estate plan, it embodies her commitment to fostering musical talent and enriching the community through education and the arts.

St. Baldrick's Foundation

The St. Baldrick's Foundation is a volunteer and donor powered charity committed to supporting the most promising research to find cures for childhood cancers and give survivors long and healthy lives. It started with a friendly dare: would you shave your head to raise money for kids’ cancer research? What happened next would change the world. This bold act of baldness has gained major momentum, since its start in 2000. Today, we have more than 1,000 head-shaving events taking place around the world at pubs, restaurants, schools, churches, parks, firehouses, military bases – you name it. It is our constituents’ way of changing the world, in a meaningful way. Volunteers also raise funds through athletic challenges, livestream fundraisers and many other activities.

Since the Foundation's first grants as an independent charity in 2005, St. Baldrick's has invested more than $380 million in childhood cancer research grants worldwide.

About Allied World

Allied World Assurance Company Holdings, Ltd, through its subsidiaries, is a global provider of insurance and reinsurance solutions. The company operates under the brand Allied World and has supported clients, cedents and trading partners with thoughtful service and meaningful coverages since 2001. Since the inception of St. Baldrick’s, Allied World has supported childhood cancer research through the Foundation, and it is the largest of many reinsurance company sponsors, making this life-saving mission a top priority.

Survivorship and Supportive Care Research Grant

These grants are for specific one-year research projects which are hypothesis-driven and focus on areas related to survivorship and supportive care of children and adolescents with cancer. Examples include but are not limited to: studies related to the burden of morbidity, cause-specific mortality, understanding the pathogenesis of treatment-related complications, patient-reported outcomes or quality of life, health communication, health promotion, and psychosocial support across the trajectory from diagnosis to survivorship or end-of-life care.

Projects must have direct applicability and relevance to pediatric cancer. They may be in any discipline of basic, clinical, translational, or epidemiological research.

Napa Valley Community Foundation

There are more than 800 Community Foundations in the US, each devoted to a specific region. We operate independently, with a common goal in mind: to be a platform for local people who want to pay it forward. To deliver resources to effective charitable programs. And to make our communities stronger and more successful by doing these two things.

Among our peers, Napa Valley Community Foundation ranks first on several key measures of donor satisfaction and impact, according to a recent donor survey conducted by the Center for Effective Philanthropy. Our donors say that we deeply understand their interests, and deeply understand the needs of Napa Valley. That, in a nutshell, is our job.

Fruit of the Vine Scholarship

The Fruit of the Vine Scholarship Fund benefits graduating Napa County high school seniors and Napa Valley College transfer students who will find the cost of higher education a financial hardship. Consideration is given to applicants who are the first in their family to attend college or are employed (or have a parent or guardian who is employed) in the Napa County wine or grape industry. Recipients of the scholarship will receive funding for up to four years of undergraduate study.

The Melanoma Career Development Award (CDA) is offered by the Melanoma Research Foundation to support researchers dedicated to melanoma and its prevention. This award is designed for postdoctoral fellows with under five years of experience, research associates, scientists, staff scientists, assistant professors, and those focusing on melanoma prevention. The initiative promotes innovative research to advance understanding and treatment of melanoma, ultimately aiming to reduce its impact.

Gilead Sciences

At Gilead, we are relentlessly committed to advancing transformative therapies for the most serious diseases, delivering an exponentially positive impact on health.

For more than three decades, we have combined scientific rigor with a deep sense of purpose to improve health outcomes and reimagine care. Our work spans more than 35 countries with a focus on three therapeutic areas: virology, oncology, and inflammation, where unmet medical needs remain greatest.

From individual patients to whole populations, we’re committed to delivering healthier futures for people and communities worldwide.

Our Mission: To discover, develop and deliver innovative therapeutics for people with life-threatening diseases.

HIV Prevention NOVA 2026

Program Description

Gilead Sciences invites research proposals that advance the evidence base for innovative and scalable models of delivery for long-acting (LA) HIV pre-exposure prophylaxis (PrEP) in the United States.

This Topic of Interest (TOI) is focused on care delivery models implemented in non-traditional settings, defined as clinical and non-clinical environments where PrEP services are not routinely provided. Emphasis is placed on approaches that reflect real-life practice and address gaps in current PrEP delivery infrastructure.

Persistent inequities in PrEP uptake in the U.S. suggest that expanding availability within traditional clinical settings alone is unlikely to reach all populations with unmet PrEP need.1,2 Rigorous implementation studies in non-traditional settings where PrEP services are not routinely provided are needed to evaluate whether these models can reduce access barriers and improve equitable reach among individuals who may benefit from PrEP.2,3,4

The goal of this TOI is to generate practical, decision-relevant evidence that informs how LA PrEP can be implemented, scaled, and sustained in real-life U.S. settings.

The Elevance Health Foundation's Food as Medicine Grant aims to enhance access to nutritious foods and improve health outcomes for individuals facing diet-related conditions. This initiative invites qualified nonprofits to submit proposals focused on scalable solutions that address food insecurity and promote health equity. The foundation prioritizes programs that demonstrate measurable outcomes and support whole-person health, particularly for populations at high social risk. Grants will be awarded for a term of 1-3 years, with funding based on program needs.

The Melanoma Established Investigator Award offers up to $125,000 annually for two years, aimed at established melanoma researchers or senior researchers transitioning into melanoma research. Eligible applicants include Associate Professors or higher, with both tenured and non-tenured faculty encouraged to apply. U.S. citizenship is not a requirement for this funding opportunity provided by the Melanoma Research Foundation.

The NIAID is focused on advancing the research and development of next-generation malaria vaccines, aiming to leverage innovative vaccine design techniques. This initiative not only aims to enhance malaria prevention but also serves as a model for combating other mosquito-borne diseases. By utilizing cutting-edge methods such as structure-based immunogen design and combination vaccines, the program seeks to significantly reduce both parasite infection rates and the overall disease burden associated with malaria.

The National Institute of Allergy and Infectious Diseases (NIAID) is calling for applications for four Leadership and Operations Centers (LOCs) as part of its HIV/AIDS Clinical Trials Network initiative. These LOCs will guide research on HIV therapeutics, prevention, and treatment strategies across diverse populations. The initiative aims to enhance evidence-based practices and improve health outcomes for individuals affected by HIV, ultimately contributing to the goal of ending the HIV epidemic.

The MRFBC Young Investigator Team Award supports innovative research in immuno-oncology for melanoma, offering up to $150,000 annually for two years. This funding targets U.S.-based researchers aiming to enhance clinical outcomes for melanoma patients or deepen the scientific understanding of immuno-oncology. The MRF collaborates with key institutions to address challenges in melanoma research, fostering partnerships that maximize research potential and impact.

The National Institute of Allergy and Infectious Diseases (NIAID) is launching a funding opportunity for up to four Clinical Trials Network Laboratory Centers (LCs). These LCs will support HIV prevention and treatment strategies by providing necessary laboratory infrastructure and technologies for clinical trials. They will ensure rigorous laboratory testing and oversight, enhance sample integrity, and utilize advanced data management systems to meet evolving demands in HIV research and testing.

About NABT

Since its establishment in 1938, the National Association of Biology Teachers (NABT) has been the recognized "leader in life science education." Thousands of educators have joined NABT to share experiences and expertise with colleagues from around the globe; keep up with trends and developments in the field; and grow professionally.

NABT Mission

The National Association of Biology Teachers empowers educators to provide the best possible biology and life science education for all students.

Climate Education Action Award

Sponsored by NCSE, this award recognizes excellence in classroom/community education that specifically supports and promotes the accurate and robust teaching of climate science and the impact of the changing climate on society beyond the classroom. This award is presented to K-12 teachers in odd-numbered years and undergraduate and/or informal educators in even-numbered years. NCSE’s sponsorship of this award includes a $1,000 honorarium. The recipient also receives a recognition plaque to be presented at the NABT Professional Development Conference and one year of complimentary membership to NABT.

The National Institute of Allergy and Infectious Diseases (NIAID) is launching a funding opportunity for Clinical Trials Units (CTUs) as part of its effort to combat HIV/AIDS. This initiative aims to support innovative clinical trials and implementation research to improve prevention and treatment strategies. With a focus on both domestic and international research sites, CTUs will play a crucial role in addressing the HIV epidemic and enhancing participant recruitment and retention. This funding opportunity is authorized under the Public Health Service Act.

Jack Kent Cooke Foundation

The Jack Kent Cooke Foundation is dedicated to advancing the education of exceptionally promising students who have financial need. Since 2000, the Foundation has awarded $304 million in scholarships to more than 3,400 students from 8th grade through graduate school, along with comprehensive academic advising, career pathway counseling and other support services. The Foundation has also provided $136 million in grants to organizations that serve such students.

The Jack Kent Cooke Foundation’s scholarship programs are designed to encourage and support outstanding students who work hard and have financial need. Our scholarships provide financial assistance and academic support to high school, undergraduate, and graduate students. In addition to the monetary award, students join a thriving network of more than 3,400 Cooke Scholars.

Young Scholars Program

The Cooke Young Scholars Program is a selective five-year, pre-college scholarship for exceptionally promising 7th grade students with financial need. It provides comprehensive academic and college advising, as well as financial support for school, Cooke-sponsored summer programs, internships, and other learning enrichment opportunities.

Program Experience

Educational Advisers support Young Scholars to maximize high school experiences and to go on to thrive at the nation’s top-performing colleges. Our programming and support may include:

• Identifying an appropriately rigorous high school.
• Engaging in four-year planning and goal-setting.
• Funding for academic and extracurricular opportunities, such as music and art lessons, supplemental academic classes and technology.
• Annual summer programs, including two required Young Scholar programs.
• Year-round Young Scholars community programming.
• Networking opportunities with a high-achieving peer community.

The Presenter Consortium for Jazz Grant, offered by Chamber Music America, supports U.S.-based presenters collaborating to engage professional jazz ensembles. This grant provides up to $39,000 for expenses like ensemble fees, concert production, and marketing. Each consortium can include up to three presenters and aims to enhance the jazz experience through live performances and streamed concerts. Eligible projects must involve CMA’s New Jazz Works grantees, fostering creativity and community engagement in jazz.

Who We Are

Broad Street Children's Foundation is committed to providing financial support to privately funded children's homes caring for the orphaned, abandoned and broken children right here in the United States.

Grant Seekers

Broad Street Children's Foundation supports self-sustaining children's homes across the United States that actively foster the development of strong, well-rounded children in their care.

Since the start of the Foundation, over $1,000,000.00 in grants have been donated to children's homes across the country. Additionally, through the Bill and Jackie Hazelgrove Scholarship Program, we have been able to assist a number of young people to continue their education and work towards a college or vocational degree.

Today, the Broad Street Children's Foundation is continuing the dream of it's original founders through the second generation. Equally as dedicated to changing the lives of children in need across America and striving to break the cycle of abuse and neglect for other children and their families.

This funding opportunity aims to support Early Stage Investigators (ESIs) in conducting preclinical HIV/AIDS research using Nonhuman Primate (NHP) models. Eligible applicants must have at least two years of postdoctoral experience and be within ten years of their terminal degree. The initiative aligns with the NIH Strategic Plan for HIV and HIV-Related Research, targeting the reduction of HIV incidence, development of therapies, and advancement in research areas related to HIV.

Incyte Corporation invites organizations to submit membership requests aimed at enhancing healthcare access for patients and advocates. As a biopharmaceutical leader, Incyte supports initiatives that align with its mission to improve patient lives through grants and contributions. Eligible entities include medical schools, associations, non-profits, and advocacy groups. Requests should comply with Incyte's regulatory standards and be submitted at least 60 days prior to the required decision date.

The Grief Reach: Changemaker Supported Community Expansion Cycle offers up to $110,000 to enhance community programs for grieving children. Organizations are encouraged to innovate and expand their services to better meet community needs. The initiative, in partnership with the Judi’s House/JAG Institute, emphasizes training and resources for effective program evaluation over a three-year period, culminating in impactful community expansion projects.