Best Large Grants for Nonprofit Organizations in Connecticut

The grant mechanism will focus on furthering the development of strategies towards improving the outcomes of Small Cell Lung Cancer (SCLC) patients through patient advocacy. Work supported through this mechanism will address important areas of need across the entire care continuum and have the immediate potential to increase research efforts, quality of life and survivorship. The overarching theme of the proposals should be centered around using patient advocacy as a tool to develop strategies toward improving outcomes for patients with SCLC. We will encourage applications on a wide variety of topics related to SCLC, including but not limited to the following:

• Patient-Centric Care Models
  • Develop and implement care models that prioritize patient needs and preferences, integrating innovative approaches from diagnosis through survivorship
• Advanced Screening and Diagnostic Technologies
  • Create comprehensive survivorship care plans addressing long-term healthcare needs, focusing on follow-up care, monitoring for recurrence, and managing chronic side effects

• Access and Equity
  • Investigate barriers to accessing quality care, clinical trials, screening and biomarker testing for SCLC patients and purpose solutions to ensure equitable healthcare delivery for diverse populations

• Technology Integration
  • Explore the use of digital health tools and technologies to facilitate better patient-provider interactions, personalized care, and continuous monitoring during the care continuum
• Patient Feedback Mechanisms
  • Establish robust feedback systems to gather patient insights and experiences and use this data to inform continuous improvements in care delivery, diagnostic technologies, treatment approaches, clinical protocols and accessible repositories to facilitate broad research collaboration

The 2026 Strategies Using Patient Advocacy to Improve Outcomes in Small Cell Lung Cancer will grant a minimum of one award of $250,000 for a period two years ($125,000 per year).

Scholarships

Since awarding our first $500 scholarship in 1987, the Saginaw Community Foundation has awarded college scholarships to area students totaling more than $13.7 million, thanks to our generous donors. Each year, over 500 college-bound or career and technical education students benefit from our scholarship awards.

Our single application process makes it easy to potentially qualify for one or more of our 260+ scholarships.

Music Scholarship

At a very early age in Alabama, Lee Essie Smith was a self-taught musician. After losing her mother as a young teenager, she began putting her God-given musical talent to work as a pianist for several churches. By the time she graduated from high school, she had learned the cosmetology trade and met Charlie McMillan, Jr.

After his wife’s death, Mr. McMillan continued his community service with the Democratic Party, Habitat for Humanity and Mt. Olive Baptist Church as an usher. Although he did not serve very long in the military, Mr. McMillan continues to exemplify the values and physical energy of the “Army Strong” slogan. He is the patriarch of the family – always dapper – and a regular attendee at church services.

The St. Baldrick's Foundation offers Infrastructure Awards to support institutions in enhancing their capacity for childhood cancer clinical trials. These grants are aimed at smaller entities lacking necessary resources, enabling them to hire personnel and acquire vital tools to increase participation. Since 2005, the Foundation has invested over $356 million in childhood cancer research, focusing on collaboration and innovation to find cures. Institutions in the U.S. are eligible, promoting broader access to crucial clinical trials.

The Emerging Scholars in Family Planning Grant, offered by the Society of Family Planning, aims to support early-career researchers in developing a family planning research portfolio. This grant provides funding for publishable scholarly research projects, including thesis or dissertation work, fostering the next generation of scholars in abortion and contraception research. By promoting diversity and inclusion, the grant seeks to build a multidisciplinary community dedicated to advancing family planning science.

The Changemakers in Family Planning Grant Program aims to address institutionalized racism in the field of family planning by providing essential support to scholars of color. Recognizing that diversity and equity are crucial for advancing research in abortion and contraception, this initiative seeks to foster an inclusive community that empowers underrepresented voices in science. The Society of Family Planning is dedicated to creating a just environment where all scholars can contribute to meaningful advancements in family planning research.

The Gender Justice Organizing Fund Grant supports initiatives led by women, girls, trans, gender nonconforming, and LGBTQI+ individuals to achieve gender justice. Organizations must prioritize community organizing and demonstrate an understanding of systemic oppression. Grants from the Bread & Roses Community Fund are crucial for groups that lack traditional funding due to their commitment to amplifying marginalized voices. The fund emphasizes long-term strategies that foster sustainable social change in the Philadelphia area.

The Richard I. Stessel Waste Management Award, presented annually by the Air & Waste Management Association, honors outstanding achievements in waste management. This prestigious award acknowledges individuals and organizations for their significant contributions to the science and practice of waste management, including technological advancements, waste regulation, and educational excellence. Named after Professor Richard I. Stessel, the award promotes innovative solutions for environmental sustainability, encouraging professionals to serve as role models in the field.

The Disability Inclusion Fund Grant, managed by Borealis Philanthropy, aims to support organizations advocating for disability inclusion, rights, and justice. As a partner in philanthropy, Borealis facilitates donor collaboratives to maximize impact across various communities and movements. Organizations interested in applying for this grant are encouraged to review the detailed FAQ for further information. This initiative is a vital step towards fostering inclusivity and promoting the rights of individuals with disabilities.

About The Glaucoma Foundation

The Glaucoma Foundation is dedicated to improving the lives of people with glaucoma. The Foundation works to encourage and support basic and applied research in glaucoma with a goal of preserving and restoring vision. We strive to be an important resource to help patients, their families, and at-risk individuals to manage their glaucoma through education and outreach.

About Research to Prevent Blindness

The mission of Research to Prevent Blindness (RPB) is to preserve and restore vision by supporting research to develop treatments, preventives and cures for all conditions that damage and destroy sight. Since it was founded 60 years ago, in 1960, RPB has channeled more than $383 million into eye research. As a result, RPB has been identified with nearly every major breakthrough in vision research in that time.

The Glaucoma Foundation (TGF) and Research to Prevent Blindness (RPB) partner annually to provide a grant aimed at supporting women and under-represented racial and ethnic minority researchers in the pursuit of glaucoma research.

The TGF (sponsored by Patricia Hill) / RPB Fellowships in Glaucoma provide one-year $10,000 fellowships focused on substantive glaucoma research, including investigation into the etiology, diagnosis and/or treatment of glaucoma, to current ophthalmology fellows with an MD, MD/PhD, PhD or other relevant degree.

This grant mechanism will focus on furthering the development of novel strategies towards improving the treatment of Small Cell Lung Cancer (SCLC). Work supported through this mechanism will address important areas of need across the entire care continuum and have the immediate potential to increase survivorship. It is expected that correlative translational research will be proposed that will enhance the understanding of SCLC.The overarching theme of the proposals should be centered around understanding the biology of SCLC and developing strategies toward improving outcomes for patients with SCLC. We will encourage applications on a wide variety of topics related to SCLC, including but not limited to the following:

• Advanced Screening and Diagnostic Technologies
  • Utilize liquid biopsies and circulating tumor DNA (ctDNA) to enhance early detection and monitoring of SCLC, providing non-invasive diagnostic and prognostic solutions
  • Investigate the clinical utility of blood-based biomarkers for improving SCLC diagnosis, monitoring treatment response, and predicting outcomes
  • Leverage artificial intelligence for the early detection of SCLC

• Disease Progression and Acquired Resistance
  • Study of molecular + clinical characteristics of rapid progressors vs. long-term responders in SCLC to tailor personalized treatment approaches
  • Leverage radiomics to identify predictive or prognostic factors such as treatment response, risk of pneumonitis, and likelihood of brain metastases
  • Investigate the underlying mechanisms of primary and acquired resistance to chemotherapy and immunotherapy in SCLC
  • Identify and validate biomarkers indicative of disease progression and/or therapeutic resistance

• Biomarkers and Immuno-Oncology
  • Identify and validate biomarkers that can predict greater responses to immunotherapy treatments in SCLC, enhancing patient selection and treatment efficacy

• Biospecimen-based research
  • Leverage real-world patient tissue and/or blood samples to enable:
    • Longitudinal studies of SCLC progression from limited-stage to extensive-stage disease
    • Investigation of tumor and microenvironmental changes before, during, and after treatment to understand the evolution of resistance
  • Develop a centralized infrastructure for biospecimen collection, with standardized protocols and accessible repositories to facilitate broad research collaboration

These awards provide a maximum of $500,000 in funding over a period of three years.

The Glaucoma Foundation: Advancing the Treatment of Glaucoma

The Glaucoma Foundation (TGF) is dedicated to accelerating breakthrough glaucoma research and helping move promising discoveries toward patients. By supporting innovative, next-generation research and connecting leading scientists and clinicians, TGF drives progress toward better understanding, diagnosis, and treatment of glaucoma, with the ultimate goal of finding a cure.

Exfoliation Syndrome and Exfoliation Glaucoma, Pressure Independent Mechanisms of Glaucoma, Neuroprotection, and the Genetics of Glaucomas that affect people under the age of 40

The Glaucoma Foundation offers grants to researchers striving to improve the lives of glaucoma patients through novel innovations and scientific advances. The areas of current focus for TGF’s Grant Research program are Exfoliation Syndrome and Exfoliation Glaucoma, Pressure Independent Mechanisms of Glaucoma, Neuroprotection, and Genetics of Glaucomas that affect people under the age of 40 years. Examples of research that may be considered range from basic science to clinical interventions, such as genetics and genomic medicine, disease modeling, assessment of ocular perfusion, artificial intelligence, and clinical research. A priority will be given to novel proposals with a viable study hypothesis leading to impactful results that are fundable at the NIH level. Initial grant funding for one year is for up to $75,000; a grantee is permitted to apply for a grant renewal of up to $75,000. A renewal grant is a one-year grant based on research findings from the initial research.

The Lois Livingston McMillen Memorial Fund at Connecticut Community Foundation provides critical support to agencies aiding victims of domestic violence in our region. Established by Lois's parents, the fund aims to promote emotional recovery and personal advancement for women and children affected by abuse. Grants prioritize immediate crisis intervention and advocacy efforts, fostering self-confidence and dignity. This initiative reflects a commitment to empowering vulnerable communities through essential services and support.

The Conchologists of America (COA) offers grants up to $2,500 for research on recent or fossil mollusks. This funding is available for projects that explore malacological topics, ensuring that the proposed work is self-contained and capable of addressing specific research questions. While COA encourages applications for amounts less than the maximum, funding is not typically awarded to high school students or for institutional overhead. This initiative supports a wide range of malacological disciplines.

The Foundation for Physical Therapy Research offers the Promotion of Doctoral Studies Scholarships for doctoral candidates, providing up to $15,000 annually. This scholarship supports students who have completed their coursework and exams, aiming to foster impactful research careers in physical therapy. Applicants may receive a total of $30,000 during their candidacy phase, with a maximum of $45,000 throughout their doctoral program. This initiative prioritizes academic excellence and alignment with APTA research priorities.

NEXT for AUTISM's grants program empowers autistic adults by funding innovative initiatives across work, home, social engagement, and health & well-being. With over 380 funded projects nationwide, the program supports 501(c)(3) organizations in the U.S. First-time grantees can apply for up to $10,000, while returning grantees may request up to $25,000. The program emphasizes community-based solutions and aims to enhance the quality of life for autistic individuals.

The Jean Griswold Foundation

The Jean Griswold Foundation (JGF) is a non-profit organization dedicated to supporting Caregivers through educational opportunities and scholarships. 

Our Mission

The mission of the Jean Griswold Foundation is to support Caregivers by providing educational scholarships* to enable them to further their training, enhance their careers, and better assist the clients they serve.

By offering educational scholarships*, our Foundation will not only make a positive impact on the Caregivers themselves, but also the clients they assist and the home healthcare agencies where they are employed, as well as help advance the overarching home-care industry.

Scholarships will be paid directly to the federally accredited educational institutions of the winning Scholars’ choosing.

Empowering Caregivers Through Education

The Jean Griswold Foundation Scholarship Program awards scholarships to deserving Caregivers who wish to further their education in a care-related field. Applicants do not have to be associated with Griswold in any way, and the funds will be paid directly to the institution where the caregiver will be receiving education.  

Our Winter 2026 Scholarship Application period is now open! Applications will be accepted until 11:59pm ET August 31, 2026. Join our email list to get the first notice of all Scholarship happenings.  

Where would we be without Caregivers? 

Their selflessness is astounding, yet they are often overlooked and underappreciated. 

The Jean Griswold Foundation is dedicated to supporting Caregivers, the backbone of the care industry. We provide educational scholarships so Care Professionals can further their training, enhance their skills, elevate their careers, and better assist the people they serve.

The Bar Success Intervention Grant Program, funded by AccessLex Institute, aims to enhance bar exam passage rates for at-risk law students and graduates. With grants ranging from $150,000 to $300,000 for programs lasting 12 to 24 months, the initiative seeks data-driven solutions that are scalable and replicable. Eligible applicants include U.S. nonprofit organizations and law schools. Programs should feature clear goals, measurable objectives, and a robust evaluation plan to ensure effectiveness and sustainability.

The Can'd Aid: Crush It Crusade Grant empowers nonprofits, local education, and government organizations to enhance recycling efforts. With grants ranging from $3,000 to $8,000, the program supports initiatives that promote recycling at community events, engage volunteers, and foster inclusive outreach. Since 2014, over 125 organizations have benefited from this funding, driving impactful change through community engagement and environmental stewardship.

The Solidaire Network's Janisha R. Gabriel Movement Protection Fund supports frontline organizers facing security threats while fostering long-term safety. With $7.9 million allocated, the fund aids groups working towards racial, climate, gender, and reproductive justice. Despite a pause on new applications due to high demand, the fund remains committed to resourcing movement partners and addressing the disproportionate targeting of marginalized leaders amidst rising aggression from right-wing forces.

The Innovations in Alzheimer’s Caregiving Awards, overseen by the Family Caregiver Alliance, recognize organizations that enhance support for family caregivers of individuals with Alzheimer’s disease. These awards highlight innovative approaches in three categories: Creative Expression, Increasing Access and Reducing Stigma, and Public Policy. Each award is valued at $20,000, and applicants must be non-profit organizations, government agencies, or universities operating within the U.S. that focus on the needs of unpaid caregivers.

The W. Storrs Cole Memorial Research Award, offered by the Geological Society of America (GSA), supports innovative research in invertebrate micropaleontology. This prestigious award honors the legacy of Dr. W. Storrs Cole, a pivotal figure in the society's history. Recipients may be previous awardees and must have published significant works in the field. The GSA aims to advance geoscience through such initiatives, fostering scientific discovery and professional growth among earth scientists globally.

Kickstart Your Project with a Mini-Grant

At H2O for Life, we never want finances to be a barrier to participating in a service project. The H2O for Life Mini-Grants are meant to be a supportive resource for teachers and students who want to kick-start their projects with us. Mini-grants of up to $500 will be awarded to support teachers and students with the necessary funds for their service-learning programs.

Our Mission

H2O for Life offers a service-learning opportunity designed to engage, educate and inspire youth to take action to solve the global water crisis by raising awareness and funds to support implementation of water, sanitation and hygiene education projects for global partner schools.

Since 2007, nearly 1 million students from H2O for Life schools have supported water, sanitation, and hygiene education projects for partner schools in the developing world.

What is H2O for Life doing to address the global water crisis?

H2O for Life’s service-learning opportunities are designed to engage, educate, and inspire youth to become global citizens. Our innovative school-to-school approach helps young people develop a concern for others by taking a major global crisis and scaling it down to a manageable size — one water project in the developing world.

Through the service-learning opportunity we provide, students learn that they can make a tangible difference for the students in their partner school.

The Jewish Foundation Professional Development Grants for Jewish Educators aim to enhance the skills of educators in local Jewish schools. Funded by the Judith A. Kaye Fund, these grants support attendance at workshops and conferences. Eligible participants include classroom educators from day schools, preschools, and synagogue schools in Greater New Haven. The initiative promotes professional development opportunities, fostering a community of skilled educators dedicated to Jewish education.

About Us

Midlands Community Foundation (MCF) is here to serve and add value to donors’ philanthropic needs by providing them an opportunity to “invest in the power of community.” It is our goal to identify current and emerging issues, channel resources to address community needs, and help prepare for the future.

MCF Mission

The mission of Midlands Community Foundation is to be a catalyst for lasting impact in Sarpy and Cass counties and to give opportunities to organizations and individuals to pursue their charitable goals.

Scholarships Through MCF

Midlands Community Foundation is committed to the futures of communities in Sarpy and Cass Counties, and across the country. Supporting higher education of students is a direct investment in the futures of these communities.

The Walt Secord “Always Sunny and 75” Memorial Trade Scholarship Application

The Fund shall annually distribute two (2) scholarships in the amount of $1,000 each.

The Talmud Torah Meyuchad Grant offers essential financial support for religious school programs catering to children with individualized learning needs. This grant seeks to enhance educational services by providing resources that improve the learning environment for students in grades K-12 with special needs. Funded by generous endowments from the Jewish Foundation, it fosters a collaborative effort involving schools, families, and the community to ensure that all children receive the education they deserve.

Marshall Community Foundation

The Marshall Community Foundation is a partnership of endowed funds established by individuals and organizations. A Board of Trustees, comprised of local community leaders, invest the pooled endowments. Income generated is then available for grants that address charitable needs in our community. Staff and trained volunteers monitor the grants to ensure fulfillment of the grant agreements.

The full circle of philanthropy is poetry in motion. The Foundation receives your gifts, grants to local non-profits, who in turn, give back by providing services to the community. Truly, the Foundation is all about improving the quality of life and making this a better place to live, work and raise a family.

Zink Family Scholarship

A scholarship awarded to residents of Marshall and surrounding townships pursuing an education or advanced training in skilled trades, as defined by the Committee and reflective of current industry needs, including but not limited to the fields of:

• healthcare technician,
• agriculture,
• information technology,
• manufacturing,
• construction or
• automotive.

The KUH P30 Resource Core Center funding opportunity invites applications for centers aimed at enhancing research in Kidney, Urology, and Hematology diseases. These centers will provide essential resources, including data and tools, to the research community, fostering collaboration through a national network with the Center Coordinating Hub. This initiative by the National Institutes of Health aims to drive innovative research and shared expertise for improved health outcomes.