Best Large Grants for Nonprofit Organizations in Connecticut

The 1772 Foundation, in collaboration with the National Preservation Partners Network, is opening its 2026 grant cycle for Historic Property Redevelopment Programs (HPRP). This initiative aims to support nonprofit organizations in the U.S. focused on historic property revitalization. Eligible organizations must hold a 501(c)(3) designation and be NPPN members. Grants typically range from $50,000 to $75,000, promoting sustainable practices that address community revitalization and heritage conservation.

The Bridge to Success Grant for Mid-Career/Senior Investigators, offered by the AASM Foundation, supports seasoned sleep and circadian science researchers seeking bridge funding while reapplying for larger grants. Eligible applicants include those with past NIH proposals that were not funded but scored. This initiative aims to retain experienced investigators in the field while ensuring a continued focus on vital research topics. The grant is a part of the AASM Foundation's commitment to advancing sleep research.

The Armstrong Foundation, established in 1949, focuses on funding educational initiatives that promote the significance of the U.S. Constitution. To be eligible, organizations must provide an IRS determination letter confirming their 501(c)(3) status. This foundation aims to enhance public understanding and appreciation of constitutional values through various educational mediums.

The JSF Scholarships aim to empower economically disadvantaged students by providing financial assistance for their education. This initiative addresses barriers to education and employment, enabling students to achieve academic success and meaningful careers. The Foundation supports various scholarship programs, partnering with schools and universities, and focusing on areas such as financial need and mentorship. By fostering educational opportunities, the JSF Scholarships contribute significantly to community development and individual empowerment.

The John H. Emery Rail Heritage Trust Grant aims to preserve the intercity rail passenger experience from 1920 to 1960. This private foundation supports projects that restore historic rail equipment and enhance passenger service. With an emphasis on operational railroads, the Trust encourages inclusive practices and the involvement of young people in rail heritage. Grant requests can reach up to $50,000, fostering opportunities for multiple annual awards to eligible organizations dedicated to rail heritage.

The Neighborhood Beautification RFP - Love Your Block Hartford invites residents to submit ideas for improving their neighborhoods through mini-grants. This program, supported by the Hartford Foundation for Public Giving, aims to combat litter, activate vacant lots, and enhance community pride. Eligible projects should be public, beautify the area, and involve at least ten volunteers. Grants of up to $2,500 are available for projects that can be completed within the specified timeframe.

The Home Depot Foundation's Path to Pro Scholarship aims to support U.S. veterans and train skilled tradespeople. With a commitment of $750 million by 2030, the Foundation has already trained over 44,000 participants. The program collaborates with industry leaders to address the skilled labor gap, offering resources and training in various trades such as carpentry and plumbing. By providing opportunities for high school seniors and graduates, this initiative fosters career development in the home improvement sector.

The Peter H. Brink Leadership Fund, supported by the National Trust for Historic Preservation, aims to enhance the capabilities of preservation organizations through mentoring and organizational development. Grants cover travel and mentor honoraria, fostering collaboration and peer-to-peer learning. Applications are accepted year-round on a rolling basis, prioritizing those who previously applied but did not receive funding. Eligible applicants include Forum members and nonprofit organizations, with a focus on innovative ideas for mentorship opportunities.

The PEDIGREE Foundation: Dogs Rule Grant aims to support innovative initiatives that enhance dog adoption rates in the U.S. Established in 2008, the foundation focuses on organizations that improve care for dogs in shelters and rescues. Grants are available to 501(c)(3) organizations with a commitment to creating best practices for increasing adoptions. The program requires a manual or toolkit to be developed and shared with the animal welfare community to ensure sustainability and broader impact.

The BioLEAP Classroom Grant, funded by the National Anti Vivisection Society, provides educators with up to $1,000 to purchase humane anatomy models, replacing traditional animal dissection methods. This initiative supports the use of innovative learning tools like 3D digital models and synthetic specimens, enhancing educational experiences while promoting ethical practices in science education. Eligible applicants must be U.S. educators teaching an anatomy lab in the upcoming school year.

The Swantz Family Foundation Grant aims to support innovative nonprofit organizations that reconnect young people with nature. Eligible organizations must be 501(c)(3) exempt, and grants are typically awarded for one year, with some exceptions for multi-year funding. Recipients are required to submit a final report detailing project activities and the use of funds within 12 months. The foundation may recover funds if misused, ensuring accountability and effective use of resources.

The National Center for Construction Safety and Health Research and Translation (U54) aims to enhance worker safety in the construction industry through innovative research and intervention strategies. By fostering partnerships and focusing on evidence-based solutions, the Center will address critical safety and health challenges faced by construction workers. The initiative aligns with NIOSH's strategic objectives, promoting collaboration among academic institutions and organizations to improve health outcomes and reduce the occupational health burden in this vital sector.

The NDEP STEM Open NFO invites innovative proposals for research and implementation of effective STEM education and outreach programs. This continuously open announcement from the Department of Defense encourages submissions that align with key initiatives, including support for community colleges and strategic partnerships. As funding becomes available, amendments detailing specific topics and submission guidelines will be released. Applicants must submit white papers to express interest in full applications for potential funding consideration.

The FY 2025 EDA Public Works and Economic Adjustment Assistance Programs aim to enhance economic growth and resilience in distressed communities. EDA invites ongoing applications for funding, focusing on innovative approaches that leverage regional strengths. The updated NOFO emphasizes timely reviews and outlines submission procedures for core programs under the Public Works and Economic Development Act. Grantees are encouraged to develop unique initiatives that foster lasting economic prosperity.

The Mark Wahlberg Youth Foundation, established in 2001 by Mark and Jim Wahlberg, aims to support youth service programs that eliminate barriers to success for inner city youth. By providing financial and community support, the foundation empowers young individuals to achieve their potential and dreams, fostering a nurturing environment reminiscent of the Boys and Girls Clubs of America, where Mark spent his formative years.

The Abbey Mural Prize, established in 1932, supports the creation and restoration of public murals across the United States. This prestigious award, administered by the National Academy of Design since 1940, emphasizes projects that enhance community engagement and social activism through art. Grants typically range from $10,000 to $40,000, with a total annual funding cap of $125,000. Eligible applicants include artists, architects, and nonprofit organizations committed to impactful mural projects.

Nestlé Purina offers pet food donations and disaster relief primarily to 501(c)(3) tax-exempt pet welfare organizations in the U.S. Their commitment includes supplying food and litter to over 900 organizations, reflecting their dedication to the well-being of pets and communities. Purina also assists during natural disasters, providing essential support to pets in distress. Organizations interested must ensure eligibility and can expect a decision within 10 business days after application submission.

The Centers of Research Excellence in Science and Technology (CREST) program, funded by the National Science Foundation, aims to strengthen research capabilities at Minority-serving institutions (MSIs). It encourages the integration of STEM research and education, promoting diversity within the workforce. Successful proposals are expected to demonstrate innovative strategies for broadening participation and achieving national competitiveness in research. CREST Centers will also foster partnerships that advance significant research themes, ensuring sustained support and development for underrepresented groups in STEM.

The Dog Enrichment Grant, offered by the Petfinder Foundation, aims to enhance the quality of life for dogs awaiting adoption through enrichment activities and items. Grants are available for play yard renovations (up to $3,000) and interactive items (up to $1,000). Applications are accepted monthly until funds are depleted, and the window closes on November 1. Eligible expenses must be utilized within three months, and reimbursement requests will not be accepted.

The Hartford Foundation for Public Giving offers Resident Engagement Grants aimed at nonprofits and community groups to enhance civic participation and trust within communities. This program supports projects that foster social issue awareness and allyship with marginalized populations through activities like community meetings and workshops. Grants range from $1,000 to $25,000 and are available for initiatives addressing various social justice issues, including housing and education.

The Pioneering Aerospace Capabilities, Engineering and Research (PACER) program is a 20-year Broad Agency Announcement (BAA) by the US Air Force aimed at advancing innovative aerospace technologies. This initiative encourages white papers and proposals for research and development to enhance technology readiness levels. It is designed to provide the warfighter with a decisive advantage through transformative technology solutions. Multiple awards are anticipated, allowing for a range of project durations and funding values.

The Find Your Light Foundation is committed to providing every child with access to quality arts education. By focusing on direct support for exceptional programs, along with education, advocacy, and outreach, they aim to highlight the importance of arts in youth development. Grants are awarded to arts education initiatives in low-income areas across North America, typically ranging from $5,000 to $15,000, with awards issued in the Summer and Winter each year.

The Make a SPLASH! Grant Contest, co-hosted by Inside Edge Safety Surfaces, offers two all-expenses-paid awards for Life Floor safety surfaces, aimed at enhancing community splash pads. The Need-Based Award targets municipalities and non-profits demonstrating financial need, with design options including planks, bubbles, and geometric shapes. Grant values range from $50,000 to $65,000, depending on project size, ensuring safety and accessibility for all users.

The PLTW Launch program, supported by Burns and McDonnell, aims to enhance student engagement in STEM education within eligible communities. This initiative will provide grants to schools that implement at least one PLTW Launch module in the 2025-2026 academic year, followed by another module in subsequent years. The program is designed to empower students with hands-on learning experiences that connect real-world challenges to essential skills, fostering a stronger future in STEM fields.

The Recordings at Risk Grant, administered by CLIR, supports the preservation of rare audio and audiovisual media of scholarly value through digital reformatting. With funding from The Andrew W. Mellon Foundation, the program aims to award $6.75 million across twelve competitions, offering grants between $10,000 and $50,000. It encourages U.S. nonprofit institutions to preserve vulnerable media, helping them to develop strategies for effective digital reformatting and promoting best preservation practices.

The Kids Run the Nation Grant Fund, managed by the RRCA, offers financial support to running clubs, schools, and nonprofits that promote inclusive youth running programs. Since 2007, the fund has awarded over $385,000 to 495+ programs, helping more than 198,500 children embrace running. Grants between $500 and $1,000 are available for structured, gender-inclusive programs that meet specific criteria, encouraging healthy lifestyles and regular participation in running activities.

The Cynthia Woods Mitchell Fund for Historic Interiors, established by George P. Mitchell in 1997, supports the preservation of historic interiors through grants ranging from $2,500 to $15,000. Eligible applicants include public agencies and nonprofits, while individuals may apply if their project involves a National Historic Landmark. The competitive selection process typically concludes within three months, with grant recipients required to match funds dollar-for-dollar. This initiative promotes education and planning activities crucial for maintaining historic interior integrity.