Best Large Grants for Nonprofit Organizations in Connecticut

The Intervention Research to Improve Native American Health (IRINAH), led by the National Institute on Drug Abuse, focuses on enhancing health outcomes in Native populations. It supports research to identify causes of health issues, develop and test effective interventions, and implement strategies that promote sustainability. Emphasizing community strengths, the initiative aims to rigorously evaluate solutions to reduce health disparities, ensuring interventions can be adapted and shared across diverse communities.

The Citi Foundation's Global Innovation Challenge invites proposals from community organizations worldwide developing innovative employment solutions for low-income youth aged 15 to 24. This initiative aims to enhance youth employability, addressing global unemployment challenges faced by millions. Eligible organizations can apply for funding to support programs such as vocational training, entrepreneurship, and financial education to empower young people. The deadline for application registration is March 4, 2025, at 12 p.m. Eastern Time.

About Us

Making a Difference, Together

The Community Foundation of Monroe County (CFMC) builds a thriving, inclusive community through the power of philanthropy. By connecting generous donors with local causes, we help ensure Monroe County remains a place where everyone can thrive. Since our founding, we’ve been a trusted steward of community resources, fostering impactful collaborations and sustainable solutions to address challenges in education, health, poverty, and community development.

Life Needs Support

Life Needs Support provides need-based financial assistance to students and young adults from the Greater Milan area who face barriers that may prevent them from completing a degree or skilled trades training program. 

Requests are reviewed on a case-by-case basis. We recognize that unexpected hardships can disrupt educational progress, including expenses related to books and supplies, medical care, transportation, childcare, trade tools.

Applications are evaluated two times each year for awarding in the six months after application and selection.

The Petit Family Foundation offers General Project Support Grants ranging from $500 to $10,000 to support local communities. Eligible organizations must have 501(c)(3) status and demonstrate programmatic capacity and leadership. The foundation prioritizes measurable outcomes and sustainability, focusing on projects that have a clear impact. Preference is given to local New England-based non-profits, while ineligible requests include funding for individuals, endowments, and political organizations. This initiative emphasizes collaboration and community alignment.

The Heistand Family Foundation Grant aims to empower children in poverty through impactful programs and partnerships. The foundation prioritizes projects that enhance human health, community well-being, and education, focusing on practical applications. Nonprofit organizations and governmental entities are encouraged to apply, particularly those located in the Omaha/Council Bluffs area or western Iowa. This grant supports initiatives that foster job skills and improve the quality of life for disadvantaged children.

Levine Impact Lab

The Levine Impact Lab powers equitable transformation by investing in nonprofit leadership, building community organizations’ capacities, and building their capacity to accelerate positive social and environmental change.

We combine venture-capital expertise and inspired philanthropic thinking to radically amplify the value of giving.

Levine Impact Lab Operational Support Program

The Levine Impact Lab’s Operational Support Program is an 18-month, high-engagement operational partnership designed to help environmental organizations move strategic and financial priorities forward.

At the core of the program is hands-on operational support: our team works side-by-side with your leaders to drive progress on a critical project, whether it’s strengthening your financial infrastructure, increasing earned revenue, or planning for growth.

This is a working partnership. The grant funding and peer-learning community are designed to support and accelerate your momentum.

We are the best fit for organizations that:

• Operate at the intersection of environmental impact and social enterprise
• Are past the startup phase but still in a critical growth stage
• See LIL as a thought partner in unlocking strategy, scale, and sustainability
• Show up with clear goals and a commitment to moving the work forward

More information about participation commitments here.

What is Operational Support?

To get the most out of this program, organizations must come prepared with a specific project, workstream, or organizational challenge they want to tackle over the 18 months with operational support. 

Potential Area(s) of Support: 

• Financial strategy and planning
• Fundraising, development and donor engagement strategy
• Cost structure analysis
• Program development or expansion
• Corporate partnership strategy 
• New location or geographic expansion
• RFP support/capital planning
• Strategic planning
• Board engagement

Find examples of what past cohorts have worked on here.

People

The success of this program relies on having the right organizational leaders at the table. Each organization must commit two senior staff members who are equipped to make key decisions, drive implementation, and stay closely involved throughout the 18-month engagement. These leaders must:

• Have clear decision-making authority and/or strong backing from the Executive Director or CEO
• Be directly involved in the project or challenge the organization is addressing
• Be able to commit time, energy, and focus to move the work forward

There will also be opportunities to include additional staff members in operational projects, as needed, to ensure the right voices and expertise are present. 

Who this might include: Executive Director and Finance Director, Business Development Manager and Operations Lead, or Marketing Manager and Development Director, depending on the nature of your project.

What We Offer

• Tailored 1:1 operational support and strategic advising
• A national cohort of up to 10 organizations
• Peer network of strategic thought partners
• Virtual and in-person workshops and events
• Private Slack channel
• Exclusive alumni programming
• Grant funds over two years
• Supportive peer-learning community
• Accelerated organizational growth and momentum through strategic partnership with LIL

View Program Flyer here.

The Goodyear Community Support Grant aims to empower nonprofit organizations that align with Goodyear's community engagement focus areas. With a strong commitment to safe, smart, and sustainable initiatives, Goodyear supports programs fostering safe mobility, inspiring students through education, and addressing environmental and societal needs. This grant serves as a catalyst for positive change, helping communities thrive by focusing on volunteerism and impactful partnerships.

The Rosenstiel Scholarship, part of the New Mexico Press Women Scholarship Fund, aims to support graduate students in journalism, communications, or law. Established in 2023, it encourages recipients to engage in investigative journalism and uphold First Amendment rights. Eligible candidates must maintain a minimum 3.0 GPA and submit relevant publications, letters of recommendation, and transcripts. This scholarship not only fosters academic excellence but also promotes ethical standards among future media professionals.

The Mary E. Kwiatkowski Social Services Scholarship Fund, offered by the Erie Community Foundation, supports female and LGBTQIA+ students pursuing social sciences and public service careers. In 2023, over $800,000 was awarded to more than 500 students for post-secondary education. This scholarship aims to eliminate financial barriers for diverse talents in Erie County's social services sector, requiring applicants to submit an essay on their public service aspirations and challenges in the Erie region.

The NIAID aims to support four Clinical Trials Networks (CTNs) by funding Statistical and Data Management Centers (SDMCs) to enhance HIV research. These SDMCs will oversee study designs, data collection, and compliance with regulatory standards while ensuring data quality and integration. This initiative is a crucial step toward ending the HIV epidemic, fostering innovative methods, and adhering to NIH data sharing policies. Applications for the SDMCs are now being solicited.

About Us

Who We Are

The National Federation of the Blind is the oldest and largest nationwide organization of blind Americans. Founded in 1940 and currently headquartered in Baltimore, the NFB consists of affiliates, chapters, and divisions in all fifty states, Washington, DC, and Puerto Rico.

What We Do

Through our network of blind members, we coordinate many programs, services, and resources to defend the rights of blind Americans, provide information and support to blind children and adults, and build a community that creates a future full of opportunities.

What We Believe

We are the only organization that believes in the full capacity of blind people and has the power to transform our dreams into reality. We believe in blind people because we are blind people—from our democratically elected leaders to our diverse nationwide membership.

Scholarship Program

Thanks to our generous partners, there are thirty $10,000 merit-based scholarships currently available. All scholarships are awarded on the basis of academic excellence, community service, and leadership. The finalists are announced every spring. They then attend our national convention in July when the winners of each individual scholarship are selected. 

Handid Braille Scholarship

This scholarship is awarded to an individual studying social science, international relations, or governmental affairs. Handid’s mission is to provide Braille and other forms of accessible media to organizations and individuals. The nonprofit specializes in Braille production in languages other than English, especially languages that do not use the Latin alphabet, and wishes to support a student with unique perspectives.

The U.S. Army Corps of Engineers (USACE) Engineer Research and Development Center (ERDC) is issuing this announcement for various research and development topic areas. The ERDC consists of the Coastal and Hydraulics Laboratory (CHL), the Geotechnical and Structures Laboratory (GSL), the Environmental Laboratory (EL) and the Information Technology Laboratory (ITL) in Vicksburg, Mississippi, the Cold Regions Research and Engineering Laboratory (CRREL) in Hanover, New Hampshire, the Construction Engineering Research Laboratory (CERL) in Champaign, Illinois, and the Geospatial Research Laboratory (GRL) in Alexandria, Virginia.

The ERDC is responsible for conducting research in the broad fields of hydraulics, dredging, coastal engineering, instrumentation, oceanography, remote sensing, geotechnical engineering, earthquake engineering, soil effects, vehicle mobility, self-contained munitions, military engineering, geophysics, pavements, protective structures, aquatic plants, water quality, dredged material, treatment of hazardous waste, wetlands, physical/mechanical/ chemical properties of snow and other frozen precipitation, infrastructure and environmental issues for installations, computer science, telecommunications management, energy, facilities maintenance, materials and structures, engineering processes, environmental processes, land and heritage conservation, and ecological processes.

The Foundation for Sustainability and Innovation Grant aims to support projects that promote environmental restoration, preservation, and education, with a focus on sustainable resource use and community development. This grant encourages innovative approaches that connect urban and rural settings, enhance biodiversity, and foster creativity in addressing societal challenges. Eligible applicants include IRS-designated non-profits that align with the foundation's vision. The foundation also supports small presses and periodicals that creatively address sustainability issues.

About Us

The American College of Obstetricians & Gynecologists (ACOG) is the leading professional membership organization for ob-gyns. ACOG champions ob-gyns in providing equitable, evidence-based care for patients today and into the future.

ACOG comprises more than 62,000 members across 12 Districts, representing regions in the United States, Canada, and Central and South America. These members maintain the highest professional standards and are united in their delivery of exceptional, respectful, science-backed care for patients. ACOG members include medical students, residents, practicing and retired physicians, and health professionals in related fields.

For nearly 75 years, ACOG has strengthened members with comprehensive, expert-reviewed practice guidelines; management tools; career development resources; and lifelong learning opportunities.

Pete and Weesie Hollis Community Service Award

The Pete and Weesie Hollis Community Service Award (formerly the President’s Community Service Award) was established by then President Richard “Pete” Hollis. The award was an outgrowth of Dr. Hollis’ presidential theme of caring for patients. Dr. Hollis felt strongly that many of the Fellows of ACOG gave hours of care and support within their community to underserved or poorly served patient populations, often with little or no remuneration or recognition.

The award is not to be given as a recognition of activities related to service to ACOG or activities that are based on support of the specialty in legislative or regulatory decisions. Recipients of the award will receive a $1,000 honorarium plus complimentary registration to the Annual Clinical and Scientific Meeting where the award is presented.

About

Founded in 1971, the Mensa Foundation was established by members of American Mensa to extend the organization’s impact. While connected by a shared purpose, the Foundation operates independently, guided by its own Board of Trustees, strategic plan, and initiatives.

Grants & Fellowships

Dissertation Mini-Grant

The Mensa Foundation empowers the next generation of researchers through its Dissertation Mini-Grant program.

Designed to support advanced doctoral students, this grant funds innovative studies that broaden our understanding of intelligence, creativity, gifted education, and related fields.

Details

The Mensa Foundation Dissertation Mini-Grant provides $2,500 to advanced doctoral students conducting research on intelligence and gifted education. By funding innovative studies, the grant promotes research that addresses the complexities of intelligence, creativity, and related fields.

Grant Components

Chelsea Groton Foundation, Inc. was established in 1998 as a Section 501(c)(3) organization. Initially endowed with a $2 million dollar donation from Chelsea Groton Bank, the Foundation has awarded over $8.1 million in grants to non-profit organizations in the Bank’s Connecticut and Rhode Island market areas.The Foundation’s mission is to support the ongoing commitment in partnership to the long-term growth of our community. Along with Chelsea Groton Bank, the Foundation is committed to belonging, equity, diversity, and inclusion, ensuring an ongoing sense of belonging for all, today and in the future.

The Marion Maccarrell Scott Scholarship, established by Gertrude F. Straub in memory of her father, supports students from Hawai'i public high schools planning to attend college on the mainland. Eligible applicants must demonstrate financial need, possess good character, and maintain a minimum GPA of 2.8. This scholarship encourages studies in fields related to history, government, and international relations, promoting an understanding of world cooperation and peace.

The Professional Formation of Engineers: Research Initiation in Engineering Formation (PFE: RIEF) program aims to foster research in the Professional Formation of Engineers (PFE) while expanding the community of researchers in this field. It targets early-career Principal Investigators (PIs) with limited experience in social science or education research, enabling them to develop expertise in engineering education research and address critical challenges in engineering formation.

The Stark County Dairy Promoters Scholarship Fund, established by the Stark Community Foundation, provides financial assistance to students from Stark County, Ohio. Eligible applicants must be pursuing college-level studies in dairy science, large animal veterinary medicine, human nutrition, or food science, and maintain a minimum GPA of 2.5. This scholarship aims to support the next generation of leaders in these essential fields, fostering educational growth and community development.

The Avon Community Fund invites local organizations, municipal departments, and resident-led groups (working with a fiscal sponsor) to apply for funding that strengthens the wellbeing, vibrancy, and resilience of the Avon community. This grant opportunity supports projects that directly benefit town residents and reflect the priorities, aspirations, and lived experiences of the community.

Community Funds at the Greater Hartford Gives Foundation was created to empower residents with resources to identify needs and champion solutions in their own towns. Each fund is guided by a committee of volunteer residents who review applications, elevate local voices, and recommend grants that respond to emerging issues, longstanding disparities, or new opportunities for improvement. These committees bring deep local knowledge and a commitment to strengthening the places they call home. 

QBE Foundation Inc.

The QBE Foundation’s focus is on creating strong, resilient and inclusive communities. We work in partnership with community organizations, working in climate resilience and inclusion – two areas where we believe we can have the greatest impact.

The QBE Foundation is one component that reflects our company’s focus, involvement, and investment in the neighborhoods where we do business, and where our employees live and work. The QBE Foundation also empowers our employees to volunteer with colleagues and community partners to make a difference for those in need. Employees can also coordinate fundraisers that are matched by the foundation.

QBE Foundation Local Grant Program

This program supports high-impact, community-based initiatives aligned to our focus on climate resilience and inclusion.

• Climate Resilience:
  • Helping communities prepare for, adapt to, and recover from climate-related risks, including preparedness, financial resilience, and risk reduction solutions.
• Inclusion:
  • Expanding access to opportunity for underserved communities through economic inclusion, workforce pathways, and removing systemic barriers.

Multiple grants of $30,000 will be awarded across our two focus areas.

The Thoroughbred Education and Research Foundation (TERF) offers grants to support education and research related to Thoroughbred horses. The foundation prioritizes funding for scholarships, educational programs, and equine research aimed at promoting thoroughbred health and welfare. Eligible applicants include qualified 501(c)(3) organizations, while those previously funded must submit reports before applying again. Notably, TERF does not provide funds for facilities caring for unwanted horses or cover overhead costs for grants.

Native Forward awards are allocated based on the financial aid information provided by the institution’s Financial Aid Office. Awards can vary, ranging from $100 to $30,000 per academic year.

Native Forward Scholars Fund members of federally and state-recognized Tribes as well as first and second-generation descendants. However, Native Forward Scholars Fund scholarship opportunities have different Tribal eligibility requirements and can be determined by submitting a Tribal Eligibility Certificate.

Land Conservation and Indigenous Languages Scholarship

The purpose of the Land Conservation and Indigenous Languages Scholarship is to provide financial assistance to eligible American Indian and Alaska Native undergraduate and graduate students enrolled full-time at an accredited institution and pursuing degrees with a focus in Indigenous languages, natural resources, land management, and conservation or cultural preservation. 

This opportunity is a need-based award.

The Bob Skiera Memorial Fund Building Bridges Initiative Grant Program supports urban forestry research and collaboration. With a maximum award of $30,000, it aims to enhance communication between arborists, urban foresters, and various professionals. The program welcomes proposals that explore the benefits of urban forests, policy implementation, and ecosystem services. This initiative honors Bob Skiera's legacy, fostering trust and cooperation within the urban planning community for sustainable urban forestry practices.

This funding opportunity aims to advance HIV/AIDS research by implementing human new approach methodologies (NAMs) to reduce the reliance on specific pathogen free (SPF) animal models. It emphasizes the integration of NAMs-enabled frameworks for in vitro testing while supporting essential SPF colony resources. The initiative seeks to enhance research rigor and reproducibility through innovative strategies that prioritize human-relevant models, ultimately improving HIV research outcomes and facilitating collaborative development in the field.

The Store-Based Giving Program by Ross Stores Foundation supports socioeconomically disadvantaged youth by providing gift cards for school or professional clothing. Organizations must be federal tax-exempt and serve at least 60% low-income youth. Eligible programs include academic achievement and life skills initiatives. Award amounts typically range from $300 to $500, depending on budget and mission alignment. Applications are not accepted from organizations that have received donations within the past 12 months.

The Jane Bruckel Early Career Investigator Award in Axial Spondyloarthritis, offered by the Spondylitis Association of America, aims to support MDs and PhDs at the Instructor or Assistant Professor level in the US and Canada. This annual $30,000 research grant promotes innovative research in ankylosing spondylitis and enhances patient care by encouraging emerging researchers to contribute to this important field.