Best Operating Grants for Nonprofits in Connecticut

The Sarah K. de Coizart Perpetual Charitable Trust, established in 1992, focuses on supporting species conservation and blindness-related services in the Northeast United States. Grants range from $20,000 to $75,000 for conservation projects and $20,000 to $50,000 for blindness initiatives. Priority is given to endangered species and innovative research efforts. Organizations must be IRS-designated public charities. The Trust does not fund individuals or matching gifts, ensuring support goes directly to impactful projects.

The US Department of Health & Human Services announces a competitive funding opportunity for the Head Start/Early Head Start programs across various states. This initiative aims to enhance services for low-income families and children, promoting their social and economic well-being. With approximately $818.3 million available, the program seeks to expand access to quality early childhood education, thereby strengthening community stability and prosperity. Interested applicants can seek further information through the OHS Operations Center.

John Estrella Foundation: Helping Hand GrantThe John Estrella Foundation for Cancer Research was founded in memory of John Estrella.

Our funding supports a clinical protocol to acquire tumor samples from kidney cancer patients who have a kidney removed. These important samples are being used to identify factors that help predict which patients are likely to require additional therapy for their disease. With our continued funding, this protocol has been expanded to other major hospitals in the area, including Brigham and Women’s Hospital, Dana-Farber Cancer Institute, and Beth-Israel Deaconess Medical Center. Purpose of the Grant: In addition to the ever-mounting cost of medicines and treatment, people with Kidney Cancer often need assistance with expenses like transportation, living expenses, home care, and childcare. The purpose of our grant is to provide support to individuals and their families experiencing financial burdens associated with a diagnosis of and treatment for Kidney Cancer.

The Connecticut Conservation Innovation Grants (CIG) program, funded by the USDA Natural Resource Conservation Service, aims to foster innovative conservation practices on private lands. While funding is unavailable for 2025, the program traditionally supports projects that enhance water quality, soil health, and wildlife habitats. CIG offers three annual funding opportunities: National CIG Classic, State CIG Classic, and On-Farm Trials, each targeting specific conservation priorities and encouraging agricultural producers' participation.

The Fence Authority Scholarship offers a $1,000 award to students pursuing a bachelor’s degree in fields that enhance community beautification, such as architecture, civil engineering, and environmental sciences. Applicants must be U.S. citizens, enrolled full-time, and involved in community service. This scholarship aims to empower students to contribute positively to society while furthering their education in impactful disciplines.

About Us

In 2020, Connecticut established the Office of Workforce Strategy as an executive branch agency to serve as the staff to the Governor’s Workforce Council to provide strategic guidance and support the implementation of workforce initiatives and investments across the state.

The Governor's Workforce Council (GWC) is Connecticut's State Workforce Board. The GWC is responsible for setting strategy and policy for the state’s Pre-K through retirement workforce pipeline, and to serve as the primary coordinator for businesses, educators, trainers, state agencies, state workforce boards, non-profits, and others.

In April 2025, the Governor’s Workforce Council published an updated Strategic Plan, designed to provide a roadmap for workforce development efforts throughout the state. The Plan is anchored by three guiding values: Collaboration; Opportunity; and Impact, and aligned across three objectives: Drive Growth; Build Skills; and Expand Access.

Career ConneCT: Work-based Learning and Employment Subsidy RFP

The ASHRAE Region I Setty Family Foundation Scholarship offers a one-year award for undergraduate mechanical or architectural engineering students attending institutions in ASHRAE Region I or those who graduated from high schools in the area. Eligible candidates must maintain a minimum GPA of 3.0 and meet specific program criteria, promoting excellence in HVAC&R education. This scholarship supports future leaders in the field, ensuring a sustainable built environment.

The JFNY Grant for Arts & Cultural Exchange supports U.S. non-profit organizations aiming to enhance understanding of Japanese arts and culture. Eligible projects include performances, workshops, and exhibitions, with priority given to those with additional funding and in areas with limited access to cultural events. Applications must be submitted at least one month prior for online projects and three months for others. The grant covers expenses like travel, publicity, and artist fees, and is reimbursed upon project completion.

The Wolf Kahn Foundation Grant supports nonprofit organizations focused on visual arts, enhancing education and artist careers through exhibitions and residencies. Grants range from $5,000 to $15,000, prioritizing projects that promote social justice and environmental awareness. Eligible applicants must be 501(c)(3) organizations located in specific regions, while school-based programs and certain other entities are excluded. This initiative honors Wolf Kahn's legacy by fostering artistic collaboration and public engagement.

The American Electric Power Foundation provides grants to 501(c)(3) organizations focused on educational improvement, particularly in STEM fields, and basic human services such as hunger and housing. Organizations must operate within AEP's service territory or have a broader beneficial purpose. The Foundation also supports social justice initiatives and environmental protection efforts. Eligible applicants must affirm compliance with anti-discrimination policies and demonstrate commitment to diversity and inclusion.

The US Department of Health & Human Services, through the NIH, invites applications for innovative approaches to implement SBIRT/P for addressing alcohol, tobacco, and other drug use in adults facing health disparities. This funding opportunity encourages research that tests screening, brief interventions, and referrals for treatment or prevention services. Applications are due on specified deadlines from February 2024 through March 2027, fostering collaboration with healthcare and community partners to enhance public health outcomes.

The Ethnic Minorities and Women’s Internship Grant supports entry-level athletics administrative positions for one academic year, promoting diversity in NCAA Division II. It provides $30,000 for intern salaries and $3,000 for professional development, benefiting six schools annually from a total budget of $180,000. Eligible applicants must be active NCAA members, with a focus on enhancing ethnic minority and gender representation in athletics administration. This initiative encourages professional growth and compliance in diverse environments.

The Great American Cleanup Grants, offered by Keep America Beautiful, aim to enhance community beautification and environmental efforts across the U.S. This initiative encourages KAB affiliates to remove litter, plant greenery, and restore public spaces, contributing to the larger goal of cleaning up 25 billion pieces of litter by 2026. With cash grants available, this program fosters collaboration among communities, promoting sustainable practices and a cleaner, greener future for all.

The Santander Charitable Sponsorship Program focuses on supporting low- to moderate-income communities primarily in the Northeast and Florida. With a commitment of $100 million in charitable giving, the program addresses key community development needs, including affordable housing, job creation, financial education, and disaster relief. Eligible organizations must have IRS 501(c)(3) status or be public agencies, demonstrating capacity to meet community needs. Unsolicited applications are not accepted.

The Patient-Centered Outcomes Research Institute (PCORI) intends to issue a Broad Pragmatic Studies (BPS) PCORI Funding Announcement (PFA) on Aug. 4, 2026, seeking to fund high-impact, patient-centered comparative clinical effectiveness research (CER) projects. This preannouncement provides potential applicants additional time to identify collaborators; obtain patient and stakeholder input on potential studies; and develop responsive, high-quality applications. 

Patient-centered CER compares at least two available health treatments, services or care delivery strategies. PCORI seeks proposals that compare clinical interventions (e.g., pharmacological and nonpharmacological treatments, screening and diagnostic approaches) and healthcare delivery system interventions (e.g., workforce, technologies, healthcare service delivery designs) to evaluate potential benefits and harms of different treatment and care delivery options, thus generating evidence that empowers patients, caregivers and the broader healthcare community with information to make informed choices that reflect their needs and preferences. 

The Bulkley Foundation Grant offers support for charitable organizations in Fairfield County, Connecticut, with a focus on those serving Norwalk. Eligible areas include animal welfare, arts and culture, civic activities, community development, education, environment, health and medical research, human and social services, and religious initiatives. This grant aims to enhance community welfare and promote various programs that benefit local residents.

Foundation for Children with Intellectual and Developmental Disabilities

The FCIDD was founded for the purpose of providing support to organizations that serve individuals with intellectual and developmental disabilities.

Mission Statement: The Foundation supports organizations which enhance the lives of persons with intellectual and developmental disabilities by promoting research, projects, education and advocacy. 

Nonprofit Project Grants

The Foundation for Children with Intellectual and Developmental Disabilities (FCIDD) funds 501(c)(3) organizations working with individuals with intellectual and developmental disabilities of all ages, primarily in the states of Maine, New Hampshire, Vermont, Massachusetts, Rhode Island, Connecticut, New York, New Jersey, Pennsylvania, Ohio, West Virginia, Delaware, Maryland, the District of Columbia, and Virginia. 

Funding Priorities

• Grants will be awarded for the purpose of primarily benefiting, including, or increasing accessibility for individuals with intellectual or development disabilities.
• Grants may be awarded for scholarships or training personnel in the care and education of individuals with developmental and/or intellectual disabilities. 
• Grants shall mainly be distributed to a Charity whose primary purpose or whose project is to support individuals with intellectual or developmental disabilities. A Charity which has a project to benefit individuals with developmental or intellectual disabilities based on financial need shall be awarded the grant money based upon its own objective criteria and without any special preference to members of Civitan or members of their family.

Grant Categories

A grant application typically fits into one of the following categories: Accessibility & Engagement; Educational Spaces; Program Area Improvements; Outreach and Education 

Accessibility & Engagement

For museums, parks, other public spaces without a specific I/DD focus wanting to make property or equipment improvements and additions to better include visitors with I/DD.

Our Mission

We are dedicated to empowering organizations that promote the arts and develop programs designed to inspire, educate, and engage. Our vision is a world where the arts are not viewed as a luxury or elective, but as a vital part of every individual’s development and well-being.

Through strong community partnerships, we harness the transformative power of the arts to elevate educational outcomes, foster creativity, and enhance quality of life.

We believe in the synergy that arises when artists, educators, advocates, and creatives from all disciplines—musicians, museum professionals, actors, writers, and teachers—come together and collaborate. It is scientifically proven that the arts play a fundamental role in youth development, nurturing healthy brain function, social growth, and emotional resilience.

Aligned with our mission, we also support initiatives that protect and utilize nature as a source of enrichment and healing. Conservation and beautification efforts are not only essential to environmental health but also to individual and community well-being. Research consistently shows that time spent in nature supports both physical and mental health, especially for children. We are committed to partnering with organizations that recognize the vital connection between a thriving natural environment and a thriving population.

Equally important is our dedication to supporting veterans. We recognize the sacrifices made by servicemen and women and believe they deserve meaningful pathways to recovery, healing, and renewed purpose. That’s why we invest in programs that provide therapeutic support, service animals, respite opportunities, and community-centered initiatives that help veterans and their families thrive. Veterans’ well-being is not only a moral imperative but also a cornerstone of a strong, resilient community.

As a charitable foundation, we remain committed to supporting initiatives that drive progress, improve lives, and create lasting, positive impact across the arts, the environment, education, and veteran support.

The P/Arts Program

The P/Arts Program was created to strengthen connections between the philanthropic, arts, and education communities, fostering meaningful collaborations that enrich learning and inspire growth.

Eligible applicants must be accredited 501(c)(3) organizations that integrate visual and/or performing arts education into their work. Through P/Arts, we seek to support programs that:

• Revitalize learning by enhancing and transforming outdated public school curricula.
• Motivate and inspire students of all ages, encouraging curiosity, creativity, and lifelong learning.
• Empower educators by deepening professional development opportunities for teachers, professors, and childcare providers.
• Bridge the gap between school and home, creating continuity in learning and support for children and families.
• Apply evidence-based, arts-based instruction proven to strengthen both academic and personal outcomes.
• Address inequities in education by helping to close the achievement gap and expand access to high-quality learning opportunities.

At its heart, the P/Arts Program reflects our belief that the arts are a powerful driver of educational transformation, unlocking potential not just in the classroom but in entire communities.

The Cigna Group Foundation is launching the Improving Youth Mental Health Grant, committing $9 million over three years to enhance mental health support for youth aged five to 18. This initiative targets post-pandemic challenges, offering resources to parents, caregivers, and youth service professionals. Nonprofits are encouraged to apply for funding between $100,000 and $150,000 to develop programs that promote social-emotional skills, enhance caregiver support, and improve access to mental health interventions in underserved communities.

Joyce C. Willis Equity in the Arts Award

The Joyce C. Willis Equity in the Arts Award is a new competitive grant as of 2025. Similar to our Creation of New Work grant, this award is designed to: 

• Foster creativity in Greater Hartford by supporting artists of color in the creation of new work
• Foster collaborations between artists of color and arts organizations that benefit the arts, the organization and the community
• Further the foundation’s mission to support and encourage excellence in the arts in the Hartford and the immediately surrounding communities. 

We hope this new program will provide greater support for artists of color in the Greater Hartford.  

The Aimlee Laderman Student Grant, offered by the Society for Ecological Restoration, supports emerging professionals in ecological restoration research. Established in 2005, this biennial grant is dedicated to Aimlee Laderman, a founding member of SER-NE. Applicants must be enrolled in or recently graduated from a relevant program, and their work must be completed by August 30, 2024. The next application cycle is anticipated in early 2025.

The Lloyd G. Balfour Foundation, established in 1973, focuses on educational support for underserved populations in New England. It offers scholarships for employees of the Balfour Company and their families, as well as funding for organizations that provide educational services in Attleboro and surrounding areas. The Foundation prioritizes programs aimed at college readiness and success, particularly for first-generation and low-income students, and encourages multi-year funding requests to enhance nonprofit sustainability.

The Express Health Information Outreach Awards aim to enhance public health by increasing access to biomedical information for U.S. health professionals and the general public. These awards support projects that improve health information literacy among consumers and caregivers, ensuring they can effectively find and utilize health information. Focused on partnerships and outreach to underrepresented communities, the initiative seeks to promote healthy behaviors, prevent illness, and improve health outcomes through informed decision-making.

Asia-Pacific Network for Global Change Research

The Asia-Pacific region, home to over half the world's population, faces challenges due to its development goals, which strain natural resources, communities, and cultural heritage. These issues are exacerbated by adverse environmental changes. While research has shed light on these problems, it's clear that more challenges lie ahead. The Asia-Pacific Network for Global Change Research (APN) is well-positioned to generate new knowledge and solutions for these evolving global change and sustainability issues by supporting collaborative research and scientific capacity development activities, particularly those aimed at training the next generation of early career professionals.

APN 2025 Call for Proposals: CAPaBLE Programmes

CAPaBLE, our scientific capacity development programme, aims to enhance the capacity of scientists, policymakers and practitioners to assess global change issues, and explore options to resolve issues towards achieving sustainability. Through CAPaBLE, we support activities that enhance capacity at individual, organizational and systemic levels.

Activities of interest under the CAPaBLE Programme

APN supports CAPaBLE activities that enhance existing capacities of developing countries at three levels of individual-based capacity development; group, organisation, network-based capacity development; and societies, governance, and system level capacity development. APN accepts CAPaBLE proposals that engage 1 or more member/approved countries. Proposals must address one or more of the following activities:

SCIENTIFIC CAPACITY DEVELOPMENT ACTIVITIES that promote the following approaches related to one or more of the six thematic areas of APN:

• Utilising and strengthening existing capacity, 
• Creating opportunities to use/instil capacity, 
• Developing new capacity through innovative approaches.

AWARENESS-RAISING AND DISSEMINATION activities through policy- and decision-making communities, civil society, and/or the general public.

SCIENCE-POLICY interfacing in the context of the priority topics.

CAPACITY DEVELOPMENT PARTNERSHIP ACTIVITIES that contribute to the capacity development components of the evolving global change arena, including the UNFCCC Paris Agreement, IPCC, IPBES, post-2015 Sustainable Development Goals, Sendai Framework for Disaster Risk Reduction, and the UN Decade of Ocean Science, and ongoing and new global change and sustainability research programmes.

Activities geared towards using SCIENCE COMMUNICATION to disseminate knowledge generated from projects, particularly to non-science audiences.

About PCORI

PCORI funds patient-centered comparative clinical effectiveness research (CER).

Our Mission

PCORI helps people make informed healthcare decisions, and improves healthcare delivery and outcomes, by producing and promoting high-integrity, evidence-based information that comes from research guided by patients, caregivers, and the broader healthcare community.

Broad Pragmatic Studies PCORI Funding

The Patient-Centered Outcomes Research Institute (PCORI) intends to issue a Broad Pragmatic Studies (BPS) PCORI Funding Announcement (PFA), seeking to fund patient-centered comparative clinical effectiveness research (CER) projects. 

Research Initiative Highlights

CER compares at least two available health treatments, services or care delivery strategies. PCORI seeks proposals that compare clinical interventions (e.g., pharmacological and nonpharmacological treatments, screening and diagnostic approaches) and healthcare delivery system interventions (e.g., workforce, technologies, healthcare service delivery designs) to evaluate potential benefits and harms of different treatment and care delivery options, thus generating evidence that empowers patients, caregivers and the broader healthcare community with information to make informed choices that reflect their needs and preferences.

Special Areas of Emphasis

For Cycle 2 2026, PCORI is particularly interested in submissions that address the following Special Areas of Emphasis (SAE) within the BPS funding opportunity. The purpose of identifying these SAEs is to encourage submissions to these areas, rather than limiting submissions to these topics. Applicants addressing one of the below SAEs should identify the area that is best associated with their research approach:  

• Addressing Obesity
• Diabetes Prevention, Care and Treatment
• Management of Urogynecological and Pelvic Pain
• Pain Management for Individuals Living With Sickle Cell Disease

In PCORI-funded research, patients and other research partners are expected to meaningfully contribute their lived experience or professional expertise to ensure studies are patient-centered, relevant and useful for healthcare decision making. Applicants must address PCORI’s Foundational Expectations for Partnerships in Research — an evidence-based framework supported by tools and resources to guide effective engagement strategies. Applicants are also strongly encouraged to consider the inclusion of a broad range of patient-centered burdens and economic outcomes. 

Broad Pragmatic Studies PFA: Category 1, Category 2 and Category 3 Study Specifications

PCORI will commit up to $120 million in direct costs through this funding opportunity. This funding opportunity contains three categories for funding:

• Category 1: Category 1 will support research projects with direct costs up to and including $5 million.

• Category 2: Category 2 will support research projects with direct costs greater than $5 million and up to a maximum of $12 million. Applications for funding under Category 2 will be required to provide additional information in the Letter of Intent (LOI) and application to justify the size and scope of the proposed research projects and to explain how additional funds are necessary with respect to the scale, scope and complexity of personnel and material resources needed to address the research question.

• Category 3: Category 3 will support research projects with direct costs up to $12 million that utilize PCORnet® to conduct observational studies and/or pragmatic trials that are national in scale. Category 3 PCORnet Studies® must include two or more Clinical Research Networks and share study progress, performance metrics and best practices with the network to promote continuous learning and improvement. PCORnet Studies® will leverage the PCORnet Common Data Model® as appropriate. Additional details about Category 3 can be found on the PCORI website.  

The NESOT Paper of the Year Award, presented by the Northeast Society of Toxicology, recognizes outstanding publications in toxicology by graduate students or postdoctoral fellows. Eligible applicants must be NESOT members affiliated with institutions in Connecticut, Maine, Massachusetts, New Hampshire, New York, Rhode Island, or Vermont. Papers must be published or in press in peer-reviewed journals between December 1, 2024, and November 30, 2025. The award includes a certificate and a $1,000 honorarium.

The U.S. Department of Transportation's Office of Small and Disadvantaged Business Utilization is offering funding to establish the Small Business Transportation Technical Assistance Center (SBTTAC) in Region 1. This initiative aims to provide crucial technical assistance and business development support to small businesses while ensuring compliance and reducing barriers. The program includes a 10-month base year with two potential option years, emphasizing the Department's commitment to accountability and support for small enterprises.