Best Grants for Small Nonprofits in District of Columbia

The Senator Paul D. Wellstone Muscular Dystrophy Specialized Research Centers (MDSRC) program is designed to enhance research on muscular dystrophy through a collaborative, center-based approach. By fostering interdisciplinary projects and providing essential training for emerging scientists, the MDSRCs aim to drive innovation in both basic and clinical research. Engaging patient and advocacy communities is a key component, ensuring research is patient-centered and informed by real-world needs. This initiative is supported by various legislative authorities.

The National Institutes of Health is funding a groundbreaking project to enhance our understanding of Type 1 diabetes (T1D) through multimodal AI. This initiative aims to integrate diverse datasets to explore the interactions of biological processes in T1D development. By leveraging advanced AI models, the research will uncover critical insights, identify biomarkers, and pave the way for personalized medicine approaches, ultimately improving prevention and treatment strategies for this complex disease.

The Alliant Credit Union Foundation, established in 2008, is dedicated to bridging the digital divide for underserved communities. By providing reliable broadband, digital literacy resources, and technology equipment, the foundation aims to promote economic empowerment and self-sufficiency. They support 501c3 organizations that share similar missions and emphasize the importance of financial literacy. Their initiatives include collaboration with community leaders and organizations to deliver essential resources where they are needed most.

About

The Community Foundation of Central Georgia was founded in 1993 by a group of citizens interested in encouraging philanthropy and strengthening communities.

The Foundation provides donors a simple, powerful, and highly personal approach to giving. Through their funds, CFCG donors support the causes and organizations that they care about, which enhances the quality of life for the people of Central Georgia.

Our vision is a Central Georgia where philanthropy thrives, communities are strong, and citizens work toward common goals.

Al Lucas Memorial Scholarship Fund

Albert James “Big Luke” Lucas was born September 1, 1978, to David E. and Elaine H. Lucas. He passed away on April 10, 2005, from a spinal cord injury he suffered during a Los Angeles Avengers arena football game. He was married to De’Shonda, and had a daughter, Mariah.

Al was a native of Macon, Georgia, graduating from Northeast High School in 1996. Following graduation, he attended Troy State University on a full athletic scholarship, and shined as a defensive lineman for the Trojans. Throughout college Al studied hard and cherished his time on the field and in 2000 was awarded the distinguished Buck Buchanan Award as the top defensive player in Division 1-AA. He was also an outstanding member of Omega Psi Phi Fraternity, Inc. He graduated in 2000 with a Bachelor of Science degree in Criminal Justice. Al went on to join the National Football League, signing as a free agent with the Pittsburgh Steelers and later playing for the Carolina Panthers. Later he joined the Arena Football League, playing for the Tampa Bay Storm, and finally the Los Angeles Avengers.

Al was a strong athlete with a heart of gold who believed in giving back to the community that supported him over the years. He especially loved working with children and served as a substitute teacher and coach at Northeast High School during the off-season. He was a member of Steward Chapel A.M.E. Church where he first learned the responsibility and power of tithing.

Al Lucas exemplified the characteristics of a scholar-athlete. He loved athletics, but knew his studies came first. He served his community and the Lord. He expected the best of himself and others. He excelled on the football field and in life. Recipients of the Al Lucas Memorial Scholarship will reflect Al’s ideals and carry on his legacy of excellence.

Purpose

• To honor the memory of Al Lucas by providing college scholarships to scholar athletes in Al’s hometown of Macon, Georgia.

Awards

• Amount of Award: $1,000, non-renewable.
• Number of Awards: 7 per year. Two awards will be given to scholar-athletes graduating from Northeast High School, Al’s alma mater. One winner shall be female and one male. The other five awards will be given to student-athletes from each of the other five Bibb County public high schools. One will be awarded at each school.

The Clifton-Whitehead Scholarship Fund, established by Edward S. Whitehead, Jr. in honor of his relatives, supports deserving students in Middle Georgia, particularly in Bibb County. This fund aims to assist students of good character facing financial challenges in obtaining a college education. Annually, approximately 12 awards of around $1,000 are granted. Eligible recipients must maintain a minimum GPA and can renew the scholarship for up to four years, provided they meet the established criteria.

The Donald & Ruby Branson Foundation Grant aims to promote environmental, educational, and social progress in America. Established by the Branson family, it seeks to instill values of community involvement and charitable responsibility in future generations. The foundation primarily supports tax-exempt organizations under Section 501(c)(3) and emphasizes the importance of education and environmental stewardship, ensuring a cleaner and more attractive world for all.

The Christine Riggins Shepherd Scholarship Fund, established by the Community Foundation of Central Georgia, aims to support students from Lamar, Pike, Monroe, Upson, or Spalding counties attending Georgia Southern University. With at least one award given annually, the scholarship amount varies. Recipients can renew their scholarships for up to four years if they maintain eligibility. Preference is given to applicants from Lamar County, promoting educational opportunities for local students.

The DoW Alzheimer’s Transforming Research Award supports innovative research aimed at reducing the risk and preventing Alzheimer’s disease and related dementias. It emphasizes projects that enhance understanding of risk factors and develop effective risk reduction strategies. Clinical research is permitted, but trials and animal studies are not. Collaboration and preliminary data are essential for proposal consideration, and an option for multiple principal investigators is available to foster partnerships.

The Willis C. Helm Charitable Trust, established in 1954, focuses on supporting organizations that work on juvenile delinquency and the development of boys from broken homes. It provides annual grants averaging between $5,000 and $15,000, with a total giving of around $60,000 for five grants each year. Eligible organizations must be 501(c)(3) exempt and preferably located in Minnesota. Applications are accepted year-round, with a deadline of March 31 for annual review.

The Alcon Foundation focuses on enhancing global eye health through charitable monetary donations to 501(c)(3) organizations. Grants aim to support programs that improve access to quality eye care and education, fostering community development. Eligible applicants must demonstrate high-quality services, well-defined goals, and the ability to report outcomes. The foundation does not fund organizations that discriminate or are not 501(c)(3) compliant, ensuring that resources are directed towards impactful initiatives.

The Civic Engagement Microgrant Grant Program, funded by Research!America, aims to enhance public engagement skills among early-career scientists. By providing financial support for innovative projects, this initiative encourages collaborations across various STEM disciplines. Grantees will develop essential skills in communication and policy-making to strengthen community ties and promote science as a national priority. This program addresses the critical need for scientists to connect with local communities and policymakers to ensure the relevance and impact of scientific research.

The National Fish Passage Program (NFPP) offers technical and financial support to restore aquatic connectivity for fish and other organisms. By improving infrastructure like culverts and bridges, the program enhances fish populations and ecosystem resilience, providing quality fishing experiences. Managed by the US Fish and Wildlife Service, NFPP collaborates with partners to implement strategic projects that align with conservation goals, ensuring biological diversity and effective use of scientific principles in project planning.

Manuel And Fillie Garcia Hispanic Scholarship

The Manuel & Fillie Garcia Hispanic Scholarship was established as a permanent fund of Taos Community Foundation in 2011.

The award is available to graduating seniors in Taos and western Colfax counties with preference to Hispanic students pursuing advancement of higher education. The scholarship is available to those applying to 4 year colleges and universities as well as 2 year vocational/trade schools.

The award amount will be determined at the time of committee review. This award is typically renewable for up to three years if a 2.5 GPA is maintained and all required paperwork is returned in accordance with the Scholarship Agreement.

Youth Service America

Youth Service America believes that youth, communities, and our democracy thrive when we all work together for the common good. YSA is a leading global nonprofit that activates young people, ages 5-25, to find their voice, take action, and acquire powerful civic and 21st Century skills as they solve problems facing their communities. YSA supports its activation campaigns with grants, training and resources, and recognition programs for young people and their adult champions. Youth-led projects use Awareness, Service, Advocacy, and Philanthropy (ASAP) strategies to create social and environmental change.

We Serve To Remember Grants

Projects that Engage 100 Youth Volunteers

YSA’s We Serve to Remember 9/11 Day of Service Grants are for organizations, schools, and youth changemakers ages 5-25 to lead service projects on or around September 11, 2026. Programming efforts should also honor and pay tribute to those who lost their lives on September 11, 2001, their families, and those who rose in service in response to that tragedy. (We suggest starting with eleven reflections about 9/11/01 and related ideas for service or service-learning projects.)

Grantees are required to engage at least 100 youth as volunteers in planning and implementing the service activities.

What are we looking for?

• Projects must be youth-led;
• Projects must include elements to honor and pay tribute to those who lost their lives on 9/11, their families, and those who rose in service in response;
• Projects must take place on or around September 11th National Day of Service and Remembrance (Friday, September 11, 2026) – between Friday, September 4 and Friday, September 18;
• Project organizers must make their best effort to recruit and engage youth volunteers who are not usually asked to serve;

Grantees are also required to provide evidence of volunteer participation and number of hours served. Approved documention includes sign in sheets, copies of pre-and-post-surveys, or reports from school attendance or volunteer management system. These documents must contain a unique identifier for each volunteer, such as the volunteer’s full first and last name, their full first name and last initial, or a volunteer/student ID number.

Reflecting on the spirit of togetherness that brought people together in the days, weeks, and months after September 11th, we are especially looking for ideas that bring together all members of the community.

The Alvin V. Palmer Scholarship Fund, established by the Community Foundation of Central Georgia, honors the legacy of Alvin V. Palmer, a dedicated veteran and entrepreneur. This fund provides financial support for college and technical school scholarships to current and former residents of Greene County, Georgia. With a commitment to enhancing educational opportunities, this scholarship aims to empower deserving students from Mr. Palmer's hometown to achieve their academic goals.

The AEESP Award for Outstanding Contribution to Environmental Engineering & Science Education recognizes exceptional teaching and educational initiatives in the field. Annually awarded by the AEESP Foundation, recipients receive a plaque, a cash prize of $500, and a $750 travel allotment for the awards ceremony. Nominations are open to all ranks, encouraging contributions that enhance student learning and improve engineering education practices.

The AEESP Award for Outstanding Teaching in Environmental Engineering & Science recognizes exceptional professors dedicated to teaching in environmental engineering. It honors those who demonstrate excellence in classroom engagement, innovative teaching practices, and mentorship. Open to nominations from all ranks, this award includes a plaque, a $500 cash prize, and a $750 travel allowance for the awards ceremony. Past winners are ineligible, ensuring fresh talent is acknowledged annually.

The Zachary Adam Giordan-Lascari Memorial Scholarship, offered by the Community Foundation of Southern New Mexico, supports fathers pursuing physical therapy education at accredited institutes. This scholarship aims to assist students from diverse backgrounds, including those with disabilities and members of the LGBTQIA+ community. With a focus on community impact, this fund exemplifies the Foundation's commitment to enhancing educational opportunities and fostering a thriving future for recipients in Southern New Mexico.

About The Children’s Heart Foundation

The Children’s Heart Foundation (CHF) is the country’s leading national organization solely dedicated to funding congenital heart defect (CHD) research. The mission of The Children’s Heart Foundation is to fund the most promising research to advance the diagnosis, treatment, and prevention of congenital heart defects. Since its inception, CHF has funded millions of dollars of CHD research across the U.S. and Canada. 

AHA/CHF Congenital Heart Defect Research Awards

The Children’s Heart Foundation partners with the American Heart Association to fund Congenital Heart Defect Research Awards. This collaborative investment of funds provides support for investigators who are actively conducting research directly related to advancing the prevention, diagnosis, and treatment of CHDs, which directly aligns with The Children's Heart Foundation's mission. 

Congenital Heart Defect Funding Opportunities

A multi-year commitment between the American Heart Association (AHA) and Children’s Heart Foundation (CHF) jointly supports Predoctoral Fellowship or Postdoctoral Fellowship investigators actively conducting basic, clinical, population, or translational congenital heart defects research.

Predoctoral Fellowship

Purpose

To enhance the integrated research and clinical training of promising students who are matriculated in pre-doctoral or clinical health professional degree training programs and who intend careers as scientists, physician-scientists or other clinician-scientists, or related careers aimed at improving global cardiovascular, cerebrovascular and brain health.

• AHA research awards are limited to U.S.-based non-profit institutions, including medical, osteopathic, and dental schools, veterinary schools, schools of public health, pharmacy schools, nursing schools, universities and colleges, public and voluntary hospitals and others that can demonstrate the ability to conduct the proposed research.

• Applicants must be AHA Professional Members at the time of proposal submission. The AHA expects all mentors associated with training/mentored research awards to maintain active AHA membership, as well.

• This award is not for individuals of faculty/staff rank.

Applicants are not required to reside in the United States for any period before applying for American Heart Association funding. However, applicants must have one of the following designations at the time of proposal submission – not award start date, depending on career stage and each individual’s situation. An awardee must maintain one of the designations listed below throughout the duration of the award. Please consult with your institution’s grant officer.

• U.S. citizen
• Permanent resident
• Pending permanent resident (must have filed Form I-485 for permanent resident status and obtained an I-797C 3 Notice of Action that the application has been received by USCIS and case is pending)
• E-3 Visa - specialty occupation worker
• F-1 Visa – student (for predoctoral and postdoctoral fellows only)
• G-4 Visa - family member of an international organization employee
• H1-B Visa - temporary worker in a specialty occupation
• J-1 Visa - exchange visitor (pre- and postdoctoral fellowships only; all other awardees must obtain an H-1B or equivalent by the award activation date)
• O-1 Visa - temporary worker with extraordinary abilities in the sciences
• TN Visa - NAFTA Professional
• DACA - Deferred Action for Childhood Arrivals

About The Children’s Heart Foundation

The Children’s Heart Foundation (CHF) is the country’s leading national organization solely dedicated to funding congenital heart defect (CHD) research. The mission of The Children’s Heart Foundation is to fund the most promising research to advance the diagnosis, treatment, and prevention of congenital heart defects. Since its inception, CHF has funded millions of dollars of CHD research across the U.S. and Canada. 

AHA/CHF Congenital Heart Defect Research Awards

The Children’s Heart Foundation partners with the American Heart Association to fund Congenital Heart Defect Research Awards. This collaborative investment of funds provides support for investigators who are actively conducting research directly related to advancing the prevention, diagnosis, and treatment of CHDs, which directly aligns with The Children's Heart Foundation's mission. 

Congenital Heart Defect Funding Opportunities

A multi-year commitment between the American Heart Association (AHA) and Children’s Heart Foundation (CHF) jointly supports Predoctoral Fellowship or Postdoctoral Fellowship investigators actively conducting basic, clinical, population, or translational congenital heart defects research.

Postdoctoral Fellowship

Purpose

To enhance the training of postdoctoral applicants who are not yet independent. The applicant must be embedded in an appropriate investigative group with the mentorship, support, and relevant scientific guidance of a research mentor. Recognizing the unique challenges that clinicians, in particular, experience in balancing research and clinical activity, this award mechanism aims to be as flexible as possible to enable applicants to develop academic careers in research alongside fulfilling clinical service commitments.

The trainee and mentor should collaboratively provide a thoughtfully planned, systematic proposal aimed at clearly answering an investigative question in cardiovascular, cerebrovascular or brain health research

• AHA research awards are limited to U.S.-based non-profit institutions, including medical, osteopathic, and dental schools, veterinary schools, schools of public health, pharmacy schools, nursing schools, universities and colleges, public and voluntary hospitals andothers that can demonstrate the ability to conduct the proposed research.

• Applicants must be AHA Professional Members at the time of proposal submission. The AHA expects all mentors associated with training/mentored research awards to maintain active AHA membership, as well.

• This award is not intended for individuals of faculty rank.

Applicants are not required to reside in the United States for any period before applying for American Heart Association funding. However, applicants must have one of the following designations at the time of proposal submission – not award start date, depending on career stage and each individual’s situation. An awardee must maintain one of the designations listed below throughout the duration of the award. Please consult with your institution’s grant officer.

• U.S. citizen
• Permanent resident
• Pending permanent resident (must have filed Form I-485 for permanent resident status and obtained an I-797C 3 Notice of Action that the application has been received by USCIS and case is pending)
• E-3 Visa - specialty occupation worker
• F-1 Visa – student (for predoctoral and postdoctoral fellows only)
• G-4 Visa - family member of an international organization employee
• H1-B Visa - temporary worker in a specialty occupation
• J-1 Visa - exchange visitor (pre- and postdoctoral fellowships only; all other awardees must obtain an H-1B or equivalent by the award activation date)
• O-1 Visa - temporary worker with extraordinary abilities in the sciences
• TN Visa - NAFTA Professional
• DACA - Deferred Action for Childhood Arrivals

Marshall High School Scholarship

The Alison Shuemake Scholarship is for a Marshall High School senior and graduates pursing an academic or technical degree or certification.

Applications are open year-round. After we receive all application requirements, we internally review applications and make decisions within two weeks of receipt. An email will be sent to the applicant to complete follow up requirements.

Scholarship payments are sent directly to the school.

Fuel Up

We’re Fuel Up – an initiative created by America’s Dairy Farmers to help meet the needs of schools across the country when it comes to fueling healthy bodies and healthy minds.

Fuel Up is all about educators, students and partners working together to make a difference in their schools and their communities.

Fuel Up is an initiative focused on helping educators and students fuel wellness in the areas that matter most, like being mindful and staying healthy. Our educational resources, partnerships and grant/funding opportunities aim to broaden access to good nutrition and overall wellness.

School Nutrition Equipment Grants

Nutrition equipment grants are now available through GENYOUth's End Student Hunger initiative, with applications now open in the new School Wellness Portal.

K-12 schools can apply for an equipment grant to help increase students' access to, and participation in, nutritious school meals.

Overview of Fuel Up Equipment Grant

• One of two nutrition equipment kits—each valued at $2,000—is available to qualified K-12 schools to improve access to nutritious foods.

• Your application must demonstrate how the funding will increase your students’ access to and their consumption of dairy products (milk, yogurt, cheese). Your local Dairy Council can help you with ideas for how to increase dairy.

• Applications will be evaluated based on a variety of factors, including school enrollment, student reach, in-school support, school location, and the sustainability of the proposed program. Consideration will be given to schools in underserved communities whose students are most at risk for poor nutrition and childhood obesity.

• You are encouraged to contact your local Dairy Council with questions about the application process. They can be especially helpful in suggesting ways to increase dairy consumption at your school.

Schools can visit the GENYOUth School Wellness Portal to review eligibility requirements, explore equipment options, and begin an application.  

Residential Substance Abuse Treatment for State Prisoners (RSAT) Program

Overview

The Residential Substance Abuse Treatment (RSAT) Program is a formula grant program that enhances the capabilities of state, local, and tribal governments to provide residential substance use disorder (SUD) treatment to adult and juvenile populations during detention or incarceration, initiate or continue evidence-based SUD treatment in jails, prepare individuals for reintegration into the community, and assist them and their communities throughout the reentry process by delivering community-based treatment and other recovery aftercare services.

The RSAT Program encourages the establishment and maintenance of drug-free prisons and jails and development and implementation of specialized residential SUD treatment for individuals with co-occurring mental health and substance use disorders. The program also encourages the inclusion of medication-assisted treatment as part of any SUD treatment protocol.

The National Swine Resource and Research Center (NSRRC) is a pivotal resource that enhances biomedical research by providing genetically modified models. This centralized facility reduces variability and costs for researchers, allowing them to focus on scientific discovery. NSRRC offers breeding, cryopreservation, and genotyping services, ensuring consistent access to high-quality models. By consolidating these resources, it promotes reproducibility and supports the development of innovative methodologies in research, ultimately advancing our understanding of human health and disease.

The Grant for Grassroots Exchange: U.S.-Japan Community Networking supports initiatives that foster connections between grassroots communities in the U.S. and Japan. With funding up to $10,000, projects should enhance mutual understanding through events like workshops and conferences. Eligibility is limited to U.S. organizations with 501(c)(3) status, and priority is given to collaborations with underrepresented groups. This grant aims to strengthen community ties and promote cultural exchange on a local level.

The Young Investigator Grant from Alex's Lemonade Stand Foundation supports early career researchers in pediatric oncology. This grant, offering up to $50,000 per year for three years, aims to cultivate promising researchers and encourage innovative research ideas. With a commitment to changing the lives of children with cancer, ALSF plays a crucial role in funding impactful research and empowering the next generation of scientists dedicated to this vital cause.

The Bernick Family Trades Scholarship, offered by CommunityGiving, aims to support high school seniors pursuing advanced education in technical or community college programs. Ten scholarships of $1,500 each are available. Eligible applicants must live in the Bernick Service Area and maintain a GPA of 3.0 or higher. Preference is given to students in fields related to the Bernick business, such as Mechanics, Transportation, and Accounting. This initiative seeks to empower local youth and foster community growth.