Best Large Grants for Nonprofit Organizations in District of Columbia

The State Biomonitoring Cooperative Agreement aims to enhance public health laboratories' ability to conduct biomonitoring and assess human exposure to environmental chemicals. This funding opportunity emphasizes community investigations, state-level studies, and emerging chemicals not covered in the National Exposure Report. By improving laboratory capacity and fostering collaboration, the initiative seeks to identify harmful exposures and evaluate intervention effectiveness over a three-year period.

The Bertha Parker Cody Award, offered by the Society for American Archaeology, supports Native American, Alaska Native, and Native Hawaiian women pursuing undergraduate or graduate studies in archaeology and museum studies. This scholarship fosters educational advancement and collaboration between archaeologists and Indigenous communities, promoting ethical practices and cultural preservation. Funded in part by the Autry Museum of the American West, it aims to empower diverse voices within the field of archaeology and is available annually.

The Guyon Scholarship for Veterans, established by Ann Guyon in memory of her husband Bill, supports U.S. military veterans from specific Wisconsin counties. It offers a non-renewable $1,000 scholarship for college costs during the first semester. Eligibility includes being a veteran and planning to attend an accredited institution. Financial need is considered, ensuring that the scholarship benefits those who require support for their educational pursuits.

The Ken and Eileen Gross Memorial Scholarship, established by friends of the couple, supports Saginaw County high school seniors pursuing a teaching degree. With a focus on fostering education, this scholarship honors Ken, a dedicated educator, and Eileen, a successful property manager. Eligible students must demonstrate a minimum 3.0 GPA and financial need, ensuring that those committed to teaching can pursue their aspirations. Awards typically range from $500 to $4,000, empowering the next generation of educators.

Implementing Germline and Somatic Testing for Precision Medicine in Community-Based Prostate Cancer Care 

The intent of this Request for Proposal (RFP) is to invite organizations to submit applications to host a 2.5-to-3 hour medical education program at or nearby the organization, to be led by 1-2 Visiting Professors (VPs) with expertise matched to the organization’s unmet educational and pragmatic needs related to integrating and acting on germline and somatic (tumor and/or ctDNA) testing for patients with prostate cancer. Following the education program, organizations will implement their action plan to incorporate, increase, or improve the use of guideline-concordant germline and somatic testing to improve prostate cancer patient care.

The total budget for the RFP is $250,000 USD, with plans to support 5-7 organizations. Individual project budgets should not exceed $50,000 USD.

About Us

The Community Foundation of Dickinson County, Inc. was established in 1999 by a group of civic-minded individuals who cherished their community and wanted to ensure future generations experience the same quality of living they had received in Dickinson County. These visionaries secured the future of the Foundation by establishing an Endowed Founder’s Fund.  

Woodrow and Esther Tyrell Technical Scholarship - (Up to 5) $10,000

The Woodrow and Esther Tyrell Technical Scholarship honors the legacy of Benjamin Woodrow Tyrell and Esther Tyrell, whose lives reflected a strong commitment to hard work, service, and education. Born in Talmage, Kansas, Woodrow Tyrell served in World War II before returning to Dickinson County, where he worked for 33 years at the Abilene Flour Mill. Esther Tyrell, originally from Longford, Kansas, dedicated her career to education in Dickinson County. Married in 1952, the Tyrells believed deeply in the value of education and skills-based training. 

About Us

The Community Foundation of Dickinson County, Inc. was established in 1999 by a group of civic-minded individuals who cherished their community and wanted to ensure future generations experience the same quality of living they had received in Dickinson County. These visionaries secured the future of the Foundation by establishing an Endowed Founder’s Fund.

Woodrow and Esther Tyrell Scholarship - (2 or more) $20,000

The Woodrow and Esther Tyrell Scholarship honors the lives and legacy of Benjamin Woodrow Tyrell and Esther Tyrell, whose commitment to hard work, service, and education continues to benefit students in Dickinson County. Born in Talmage, Kansas, Woodrow Tyrell served in World War II before returning home to work at the Abilene Flour Mill for 33 years. Esther Tyrell, originally from Longford, Kansas, was a longtime educator in Dickinson County. Married in 1952, the Tyrells shared a strong belief in the importance of education. Through their generous endowment at the Community Foundation of Dickinson County, their legacy continues to support students and foster brighter futures through educational opportunity.

Who We Are

Nevada Women’s Fund is a dedicated nonprofit organization committed to empowering women and strengthening communities across Nevada. Since our founding, we have worked to identify and fund critical initiatives that support women’s education, career development, and personal growth. Through scholarships, grants, and collaborative programs, we aim to break down barriers and create opportunities that foster self-sufficiency and achievement. Our mission is driven by a vision of a Nevada where women can thrive, lead, and make lasting contributions to their families, workplaces, and communities.

"The best way to empower women is to educate them.” ~ Michelle Obama

Scholarship History

Nevada Women's Fund scholarship program was established to empower women in Northern Nevada by supporting their educational pursuits. Since its inception, the program has awarded millions of dollars in scholarships to women across the region, helping them achieve their academic and career goals. Over the years, the program has expanded to include support for students in a variety of fields, with a focus on fostering economic self-sufficiency and professional advancement. Through this commitment, Nevada Women’s Fund continues to invest in the potential of women to drive positive change in their communities.

Workforce Ready Scholarships

These scholarships support individuals pursuing education and training pathways outside of a traditional academic degree program, such as:

• Certificate Programs
• Trade or Vocational Training
• Continuing Education or Professional Development
• Licensing

The Lowe's Foundation Gable Grants Program aims to address the skilled trades labor shortage by investing $50 million over five years to train 50,000 job-ready workers. The program supports community and technical colleges, as well as community-based nonprofit organizations, to enhance their skilled trades education initiatives. Eligible organizations can apply for grants from March 1, 2025, to October 1, 2025, to foster workforce development in essential trades such as HVAC, plumbing, and construction.

About Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Who we are and our impact

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Amyloidosis

Help with healthcare costs for amyloidosis

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

About the disease

Amyloidosis is characterized by a build-up in amyloid protein in specific organs or throughout the body. It is a rare disease that affects multiple systems. Subtypes include hereditary amyloidosis, light chain amyloidosis (AL amyloidosis), and amyloid A (AA) amyloidosis (secondary amyloidosis).

The SBE Postdoctoral Research Fellowships, offered by the National Science Foundation (NSF), are designed to promote early-career independence by supporting research and training goals in the social, behavioral, and economic sciences. Applicants can choose between two tracks: Fundamental Research and Broadening Participation. This initiative addresses significant scientific questions, aligning with NSF's mission to enhance the scientific workforce and foster diversity in research fields.

The Grant for Grassroots Exchange: Japan Festivals and Events supports cultural projects promoting understanding of Japan through local festivals and events. Aimed at community-driven initiatives, the grant encourages cross-cultural exchange and global perspectives while providing up to $7,000 in funding. Priority is given to projects reaching underserved communities in the Midwest, Mountain, and South regions, involving new participants in K-12 education, and demonstrating potential for replication in other areas.

The AbbVie Foundation Health Equity Accelerator seeks innovative solutions to enhance healthcare access for underserved communities. This program empowers nonprofit organizations by providing mentorship, resources, and financial support, including a $10,000 stipend for participants and a $50,000 grant for the best solution. By fostering community-led initiatives, the accelerator aims to address health disparities and improve the quality of care through tailored, grassroots approaches. Applications are encouraged from organizations rethinking care delivery models.

About Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Who we are and our impact

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Cushing’s disease or syndrome

Help with healthcare costs for Cushing's disease or syndrome

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

About the disease

Cushing’s Disease or Syndrome, also known as Cushing’s Syndrome, hypercortisolism and hyperadrenalism, is a condition where the pituitary gland releases high levels of the hormone cortisol. It is a rare disease that affects the endocrine system.

The Emily and Frank Smiddy Scholarship Endowment, established by the Grand Traverse Regional Community Foundation, offers financial support to graduating seniors from Benzie County high schools pursuing postsecondary education in sciences or STEM fields. This scholarship can be renewed annually for up to four years, helping students achieve their educational goals and contribute to the community's growth and development.

The BRAIN Initiative aims to foster innovation in the development of next-generation devices for recording and modulating the human central nervous system. This funding opportunity encourages clinical studies and translational research to create advanced therapeutic and diagnostic devices for neurological disorders. Applicants are advised to submit Letters of Intent 60 days before the proposal deadline. This initiative emphasizes milestones and collaboration with NIH staff throughout the project.

The AHA Institutional Research Enhancement Award (AIREA) aims to bolster cardiovascular and brain health research at smaller educational institutions that lack significant NIH funding. With a budget of $100,000 annually over two years, the award supports various research areas, encourages student involvement, and strengthens institutional research environments. Eligible applicants include accredited U.S. non-profit institutions with specific funding limitations, ensuring that deserving projects receive vital support for advancing health-related research.

The Freshman Winner's Circle Scholarships, established by the Iowa Foundation for Agricultural Advancement, aim to support high school students graduating in Spring 2026 who are pursuing degrees in agriculture. These scholarships encourage participation in livestock projects and reward dedication to the agricultural field. Eligible students must enroll in a post-secondary agricultural program at a university or college starting Fall 2026, fostering future leaders in the agricultural industry.

The Charles E. Crow Memorial Scholarship Fund, established in 1953, supports graduates of Big Pasture High School in Randlett, Oklahoma, by providing a one-year scholarship up to $5,000. This initiative aims to enhance educational opportunities for students pursuing college, community college, or trade school certifications. Applicants must demonstrate financial need and maintain a minimum GPA of 2.8. By investing in the potential of local youth, this fund contributes to building thriving communities and advancing equity in education.

This Funding Opportunity Announcement (FOA) aims to advance the identification and evaluation of candidate biomarkers for neurological and neuromuscular disorders. By facilitating the clinical development of neurotherapeutics, the FOA encourages research that includes both animal studies and preliminary human evaluations. The ultimate goal is to produce biomarkers ready for rigorous analytical and clinical validation, enhancing the effectiveness of treatments in clinical practice.

The Strategic Research Grant for Sleep Health Disparities Research, offered by the AASM Foundation, aims to address significant gaps in knowledge related to sleep disorders among disadvantaged populations in the U.S. This initiative focuses on enhancing screening, diagnosis, and treatment effectiveness, while promoting innovative interventions tailored to culturally diverse groups. The grant supports impactful research that seeks to mitigate sleep health disparities, ultimately improving health outcomes for racial/ethnic minorities, socioeconomically disadvantaged individuals, and other underserved communities.

The Carter Creech Scholarship offers financial support up to $8,000 for graduating seniors of Troy Buchanan High School in Missouri who aim to pursue a four-year degree. Eligible candidates must maintain a minimum 3.5 GPA, achieve an ACT score of 27 or higher, and rank in the top 10% of their class. This scholarship encourages academic excellence and allows recipients to reapply annually for up to $32,000 over four years, fostering educational opportunities in the community.

The Orran "Buzzy" Calhoun Memorial Scholarship Fund, established by the Stark Community Foundation, supports graduates and current seniors from select high schools in western Stark County. Eligible applicants must maintain a minimum GPA of 3.0, pursue a full-time degree at a college or university, and demonstrate significant academic and extracurricular involvement. This fund reflects a commitment to empowering local students through educational opportunities, fostering community growth and development.

The Joyce Bytof Memorial Cancer Survivors Scholarship, established by Joyce Bytof in collaboration with the American Cancer Society, supports childhood cancer survivors graduating from specific Wisconsin high schools. This scholarship aims to assist them in pursuing higher education despite the financial and academic challenges posed by their experiences. Joyce's legacy continues to inspire hope and resilience among young survivors as they strive for academic success and a brighter future.

The Margaret Ferris Scholarship for Hard of Hearing Students, established by Margaret Ferris, a dedicated teacher, supports hard of hearing students from Calumet, Outagamie, and Winnebago counties. It aims to assist graduating high school seniors pursuing higher education. This scholarship honors Margaret's impactful career and commitment to the deaf community, emphasizing aural/oral training over American Sign Language. By providing financial aid, it continues her legacy of fostering educational opportunities for hard of hearing individuals.

The AAUW Branch and State Affiliate Community Action Grants aim to empower AAUW branches and state organizations by providing up to $10,000 for innovative STEM programming targeted at girls in grades K-12. This initiative is designed to foster hands-on learning experiences, expand local impact, and showcase AAUW's commitment to gender equity in STEM. By collaborating with other organizations, AAUW seeks to build confidence and inspire the next generation of female STEM leaders.