Best Large Grants for Nonprofit Organizations in District of Columbia

The Tribal Epidemiology Centers initiative aims to support currently unserved areas through a new cohort of TEC sites. Funded by the US Dept. of Health & Human Services: Indian Health Service, this program seeks to enhance public health capacity within tribal communities, ensuring access to essential health services and resources. The initiative underscores a commitment to addressing health disparities and promoting wellness among Native populations.

Grand Rapids Community Foundation

Connecting people, passion and resources

The Community Foundation is a nonprofit organization that connects people, passion and resources. With our partners, the Community Foundation uses the tools of philanthropy to find solutions to pressing issues. We provide grants to support the work of nonprofits, scholarships to local students and other forms of support to communities working to eliminate barriers to opportunity, prosperity and belonging.

Our Mission is to build and manage our community’s permanent endowment and lead the community to strengthen the lives of its people.

We envision a magnetic and interconnected West Michigan community.

Integrity, Excellence, Inclusion, Sustainability and Bold Aspirations

Give and Receive Openly, Build Trust with Each Other, Create Brave and Safe Space, Embrace Vulnerability, Accountability

Our North Star

For West Michigan to grow and prosper, we must make sure that everyone can apply their talents and creativity to fuel our future. It is only by connecting across perspectives and overcoming inequities that we can build and sustain an inclusive economy and thriving community.

Opportunities for students

Apply for scholarships to support your ambitions

Each year Grand Rapids Community Foundation supports hundreds of students on their college or career training journeys. We are excited to remove barriers to academic success so that students like you can pursue what you're passionate about.

Scholarship Fund Details

Support for West Michigan Students

Attending college or trade school increases opportunity and opens doors to careers. Donor partners who establish a scholarship fund give students a boost on their path to higher education. Students who complete the general scholarship application are considered for these scholarships.

Open to full time, third-year or higher undergraduate students who are 2+ year residents of Kent County enrolled in a STEM major.

The Mary L. Fenker Scholarship, established in memory of a dedicated educator, supports graduating seniors from Erie County, Ohio, pursuing undergraduate degrees. Since 1995, the Erie County Community Foundation has prioritized community needs, offering this scholarship to enhance the quality of life in the region. Preference is given to African American students from Sandusky High School, with financial need considered. Renewable for up to three years, the scholarship aims to empower students to achieve their educational goals.

Grand Rapids Community Foundation

Connecting people, passion and resources

The Community Foundation is a nonprofit organization that connects people, passion and resources. With our partners, the Community Foundation uses the tools of philanthropy to find solutions to pressing issues. We provide grants to support the work of nonprofits, scholarships to local students and other forms of support to communities working to eliminate barriers to opportunity, prosperity and belonging.

Our Mission is to build and manage our community’s permanent endowment and lead the community to strengthen the lives of its people.

We envision a magnetic and interconnected West Michigan community.

Integrity, Excellence, Inclusion, Sustainability and Bold Aspirations

Give and Receive Openly, Build Trust with Each Other, Create Brave and Safe Space, Embrace Vulnerability, Accountability

Our North Star

For West Michigan to grow and prosper, we must make sure that everyone can apply their talents and creativity to fuel our future. It is only by connecting across perspectives and overcoming inequities that we can build and sustain an inclusive economy and thriving community.

Opportunities for students

Apply for scholarships to support your ambitions

Each year Grand Rapids Community Foundation supports hundreds of students on their college or career training journeys. We are excited to remove barriers to academic success so that students like you can pursue what you're passionate about.

Scholarship Fund Details

Support for West Michigan Students

Attending college or trade school increases opportunity and opens doors to careers. Donor partners who establish a scholarship fund give students a boost on their path to higher education. Students who complete the general scholarship application are considered for these scholarships.

Four scholarships are awarded, two in honor of George J. Slykhouse, the founder of the Economic Club.

The Urban Indian Health 4-in-1 Program is designed to enhance the health and well-being of urban Native Americans through targeted initiatives in immunization, health promotion, disease prevention, mental health support, and addressing alcohol and substance abuse issues. Funded by the US Dept. of Health & Human Services, this program aims to improve access to essential health services and foster healthier communities among urban Indian populations.

The Youth Regional Treatment Center Aftercare Program aims to support American Indian and Alaska Native youth in maintaining safety, sobriety, and success post-discharge from Youth Regional Treatment Centers. This initiative enhances culturally relevant, community-based aftercare by fostering care coordination, building partnerships, and addressing barriers to improve youth outcomes.

The TTF Advertising for the Environment Grant, established by the Temper of The Times Foundation in 1997, aims to enhance awareness of wildland conservation through marketing initiatives. This grant is exclusively available to 501(c)(3) nonprofit organizations and funds various advertising campaigns to protect native ecosystems. Priority is given to projects that demonstrate measurable impacts on conservation, rather than those focused solely on education.

Grand Rapids Community Foundation

Connecting people, passion and resources

The Community Foundation is a nonprofit organization that connects people, passion and resources. With our partners, the Community Foundation uses the tools of philanthropy to find solutions to pressing issues. We provide grants to support the work of nonprofits, scholarships to local students and other forms of support to communities working to eliminate barriers to opportunity, prosperity and belonging.

Our Mission is to build and manage our community’s permanent endowment and lead the community to strengthen the lives of its people.

We envision a magnetic and interconnected West Michigan community.

Integrity, Excellence, Inclusion, Sustainability and Bold Aspirations

Give and Receive Openly, Build Trust with Each Other, Create Brave and Safe Space, Embrace Vulnerability, Accountability

Our North Star

For West Michigan to grow and prosper, we must make sure that everyone can apply their talents and creativity to fuel our future. It is only by connecting across perspectives and overcoming inequities that we can build and sustain an inclusive economy and thriving community.

Opportunities for students

Apply for scholarships to support your ambitions

Each year Grand Rapids Community Foundation supports hundreds of students on their college or career training journeys. We are excited to remove barriers to academic success so that students like you can pursue what you're passionate about.

Scholarship Fund Details

Support for West Michigan Students

Attending college or trade school increases opportunity and opens doors to careers. Donor partners who establish a scholarship fund give students a boost on their path to higher education. Students who complete the general scholarship application are considered for these scholarships.

Open to full time undergraduate students who are residents of Kent County, and are a child of a veteran of first responder who was killed or disabled while on duty.

The Asthma and Allergic Diseases Cooperative Research Centers (AADCRC) program, supported by the National Institute of Allergy and Infectious Diseases (NIAID), aims to enhance research on asthma and related allergic diseases. This initiative fosters multi-center, multidisciplinary research to explore disease mechanisms and treatment responses. By promoting clinical trials and observational studies, the AADCRC seeks to advance understanding and improve interventions for conditions such as asthma and food allergies, ultimately benefiting public health.

The Clinical Data, Safety and Statistical Centers (CDSSC) program, supported by the National Institute of Allergy and Infectious Diseases (NIAID), aims to enhance clinical research through comprehensive support. This includes statistical analysis, protocol development, and oversight of safety monitoring in studies related to asthma, autoimmune diseases, and transplantation. By coordinating these efforts, the program seeks to facilitate impactful research outcomes and improve public health outcomes through informed data-driven decisions.

Community Foundation of the Fox River Valley

The Community Foundation of the Fox River Valley is a collection of individual funds and resources given by local citizens to enhance and support the quality of life in the Fox River Valley of Illinois.

We are a tax-exempt public charity that allows individuals, businesses, and non-profit organizations to establish permanent endowments and temporary funds within the confines of one large foundation.

Foundation funds are used to provide grants to non-profit organizations and scholarships to area students. The Foundation also hosts a Youth Engagement in Philanthropy (YEP) program, which helps high school students learn more about philanthropy and empowers them to make a difference in the community.

The Community Foundation of the Fox River Valley serves the City of Aurora, Kane County, and Kendall County within the State of Illinois.

Theodore Silseth Nelson Scholarship Endowment Fund

This fund provides scholarships to students returning to school after a lapse of several years since high school graduation. The awards are given to students pursuing a two or four-year degree in health care, with a preference for both financial need and students seeking a registered nurse certification. Theodore Nelson (1937-2017) was employed as a large commercial account underwriter in the insurance industry. He created this fund out of respect for the competency of those in the healthcare profession and to encourage those who wish to improve themselves by returning to school after being in the workforce. 

The Lois Lenski Covey Foundation offers the Bookmobile Grant to promote literacy among underserved children. Grants range from $500 to $3,000 specifically for purchasing books for youth from preschool to grade 8. Eligible organizations include 501(c)(3) nonprofits and public libraries that operate lending bookmobiles. The Foundation aims to ensure access to quality literature, fostering a love of reading in disadvantaged communities while addressing their limited book budgets.

The National Institute of Environmental Health Sciences (NIEHS) invites applications for the Superfund Hazardous Substance Research and Training Program (P42 Clinical Trial Optional). This program supports interdisciplinary research centers focused on biomedical and environmental science. Eligible institutions must be accredited higher education establishments. Applications are due by 5:00 PM local time, and successful submissions will undergo a rigorous peer-review process to ensure quality and relevance in addressing hazardous substance issues.

Community Foundation of the Fox River Valley

The Community Foundation of the Fox River Valley is a collection of individual funds and resources given by local citizens to enhance and support the quality of life in the Fox River Valley of Illinois.

We are a tax-exempt public charity that allows individuals, businesses, and non-profit organizations to establish permanent endowments and temporary funds within the confines of one large foundation.

Foundation funds are used to provide grants to non-profit organizations and scholarships to area students. The Foundation also hosts a Youth Engagement in Philanthropy (YEP) program, which helps high school students learn more about philanthropy and empowers them to make a difference in the community.

The Community Foundation of the Fox River Valley serves the City of Aurora, Kane County, and Kendall County within the State of Illinois.

Robert L. & Marjory J. Nelson Memorial Scholarship Endowment Fund

This fund provides scholarships to students pursuing a career in the medical field of study with a preference to those students entering the field of nursing.

Marjory Nelson (1928-1998) received her bachelor of arts degree from Aurora University and her R.N. certification from the Copley Hospital School of Nursing.

She also undertook additional graduate studies at Northern Illinois University and the National College of Education.

She was employed by Copley Memorial Hospital and later served as a nurse for the East Aurora Schools.

This fund was created by Mrs. Nelson’s family and friends to provide recognition of her extraordinary dedication to the field of nursing.

Upon the passing of her husband Robert, the Nelson family added his name to the fund.

Robert Nelson (1924-2015) was a veteran of World War II. He served with the Navy in Europe and the Marines in the Pacific.

He worked in the field of education and was a retired principal in School District 44 in Lombard, Illinois.

Mr. and Mrs. Nelson were survived by two daughters and three grandchildren.

Created in 2004, the fund became an endowment in 2005.

Justamere Foundation

Our goal is to remove barriers that are keeping hard working people from being fully self-sufficient. We support programs that are addressing these obstacles, big and small, in a way that opens a path to self-reliance.

The Justamere Foundation is dedicated to working with our community partners to find innovative ways to help our neighbors through education, coaching, and connections.

Small solutions can result in enormous change. The Justamere Foundation’s mission is to find those needs and connect them to the right resources to make the biggest impact.

Areas of Need We Support

The Justamere Foundation’s mission is to find those areas that are underserved by traditional resources and see if we can make a bigger difference with direct involvement. Solutions might involve grants, non-traditional scholarships or simply making the right connection.

We focus on four main areas of need in our community:

• Trade Education: Individuals working towards obtaining a family-sustaining income encounter many small barriers that can impede their progress. We’ve partnered with local community colleges and organizations that work to eliminate the barriers.
• Veterans Resources: Veterans entering the civilian workforce can struggle to find the right fit. We’re working with organizations to support veterans with this process.
• Childhood Literacy: Reading is essential. Fostering a love of reading and learning opens so many doors as children grow up. We support organizations with programs that focus on education and literacy resources for children in underserved areas.
• Arts Education: Arts programs inspire and help children express themselves. We support summer and after-school programs in music, art, and theatre.

How do we support these areas?

• Non-Traditional Scholarships
• Grants that make a real impact

Non-Traditional Scholarships

There are many traditional Scholarship and Financial Aid resources for high school kids going on to college. This is great but it leaves a whole lot of people out of the solution. Kids who couldn’t go directly to college or didn’t finish highschool – Adults who are in a job that cannot effectively support their family and want to make a change – or anyone simply looking for a better life. The resources available to them are limited. We want to work with organizations that are addressing those challenges and see if there’s a connection to be made, an existing program to utilize or even a new program to be developed.

This program aims to enhance education for healthcare professionals regarding new therapies and patient management in ulcerative colitis (UC). It focuses on multi-channel educational strategies to address the evolving landscape of UC treatment. Key areas include educating on new oral therapies, transitioning to advanced therapies, and managing isolated proctitis. Organizations such as healthcare institutions and medical education companies are eligible to apply, ensuring a comprehensive approach to improving UC care.

The NRF Foundation provides access to the education and opportunities needed for successful retail careers, helping people build better lives and stronger communities.

Retail Training Initiative

Building Career Pathways Through Retail Training

The NRF Foundation Retail Training Initiative expands access to industry‑recognized retail training and credentials for job seekers across the United States. Through partnerships with community‑based organizations, workforce development providers, and educational institutions, the fund equips individuals with the skills, confidence, and credentials needed to secure meaningful employment and advance in retail and related industries.

Retail is the nation’s largest private‑sector employer and offers accessible entry points, transferable skills, and clear pathways for career growth. By investing in training that aligns with employer needs, the NRF Foundation Retail Training Initiative helps individuals overcome barriers to employment while strengthening the talent pipeline for the retail industry and beyond.

Organizations selected to participate in the NRF Foundation Retail Training Initiative receive support designed to help them deliver high‑quality, employer‑aligned training programs, including:

• Access to the NRF Foundation RISE Up training and credentialing program
• Capacity awards to support program implementation and delivery
• Tools and resources to help participants earn industry‑recognized credentials

Together, these resources help organizations expand their impact and better support job seekers on their path to employment and career growth.

TryMarine Grant

The Reservoir Fish Habitat Partnership (RFHP) is seeking candidate pilot sites for evaluating two water quality treatment technologies—TryMarine and Oase Water Technology—in small urban fishing lakes (1–3 acres).

Urban fishing lakes are important community resources, providing accessible angling opportunities and supporting local outdoor recreation. Many of these lakes experience nutrient‑driven water quality impairments such as algal blooms, low dissolved oxygen, and reduced water clarity. These issues degrade fish habitat and diminish angler satisfaction.

This pilot initiative aims to identify lakes where these technologies can be tested to determine their effectiveness, feasibility, and potential for broader application across the RFHP network.

Objectives

Water Quality & Habitat Objectives

• Reduce nutrient concentrations (total phosphorus, total nitrogen).
• Improve water clarity and reduce turbidity.
• Reduce harmful algal blooms (HABs).
• Increase dissolved oxygen stability to support sportfish populations.
• Improve habitat conditions for stocked and naturally occurring fish species.
• Reduce internal nutrient loading from sediments.

RFHP Program Objectives

• Demonstrate scalable tools for improving fish habitat in small urban lakes.
• Support community‑based fisheries enhancement.
• Provide case studies and data for future RFHP guidance.
• Strengthen partnerships among agencies, municipalities, NGOs, and angling groups.

Beckley Area Foundation

Beckley Area Foundation was established in January 1985 by ten community-minded citizens. It began with a gift of $1.1 million from the Dr. Thomas Walker Memorial Health Foundation as “seed” money for this Raleigh County project. BAF assets have grown to over $70 million with over 500 different funds managed by our three trustee banks. Today, Beckley Area Foundation is one of West Virginia’s largest community foundations.

Since its inception, BAF has distributed over $23 million to charities and other worthy projects in the fields of education, public recreation, health & human services, the arts, animal services and beautification.

Scholarships

The Beckley Area Foundation proudly manages scholarship funds established by individuals, businesses, and organizations dedicated to helping students pursue higher education. Many of these scholarships are tailored for specific schools, fields of study, or graduates from local high schools, while others offer broader opportunities. No matter the path, our scholarships aim to support students from our region as they work toward achieving their educational goals.

Most of these scholarships must be awarded to students from our geographic area or at least preference given to such students. While the majority of scholarships benefit Raleigh County applicants there are others designated for Fayette, Summers, Webster, and Wyoming students. 

The File Girls Cystic Fibrosis Scholarship

Weighted for educational merit, personal achievement and financial need; West Virginia high school matriculating senior with a confirmed diagnosis of Cystic Fibrosis. Recipient will provide physician’s letter affirming a diagnosis of Cystic Fibrosis as part of the application process; The scholarship is to be awarded for post-secondary education through college, vocational or technical schools.

This scholarship is renewable.

Tree and Soil Research Fund for Landscape Architecture Grant Program

The TREE Fund Board of Trustees is launching the new Tree and Soil Research Grant, made possible by a permanently restricted endowment fund supporting areas of research of interest to the landscape architecture community with special focus in the area of trees and the soils that support them. Projects are expected to be completed within one to three years, with a maximum award value of $10,000. No project may receive more than one award from this program. 

Award amount:

• up to $10,000 (minimum $5,000) 

The Maternal, Infant, and Early Childhood Home Visiting Program (MIECHV) aims to enhance maternal and child health, promote early childhood development, and support family well-being. By providing voluntary, evidence-based home visiting services to pregnant women and families with young children, the program addresses critical needs in communities. Funded by the US HHS: Health Resources & Services Administration (HRSA), MIECHV empowers families through tailored support and resources, fostering healthier outcomes for mothers and their children.

The CAFE Group 

We resource leaders, invest in their genius, and bring people together to reimagine what philanthropy can do.

Founded by Liz and Don Thompson, The CAFE Group is a national nonprofit transforming how change is resourced. 

With a focus on education equity, social capital, and philanthropic transformation, we pair catalytic funding, community-rooted leadership development, and cross-sector collaboration to strengthen the people and institutions shaping a more just future. Everything we do is grounded in relationship, because we believe the way resources move matters just as much as where they land.

The 1954 Project Luminary Award

The 1954 Project Luminary Award celebrates transformational education nonprofit leaders dedicated to serving Black students and communities through powerful investments in their organizations' ability to create lasting change.

The Luminary Experience

Each Luminary organization gets more than funding. Through The 1954 Project, leaders gain a community, a platform, and space to grow with tailored support over the course of the three year journey.​

• $1 Million, Unrestricted: Catalytic funding to expand what’s working.
• Leadership Coaching + Capacity Support: Guidance from peers and experts who are committed to helping you build a lasting, impactful organization.
• National Network: Luminaries join a powerful community of innovators, change-makers, and visionaries driving systemic progress to support students and communities across the U.S.

The 1954 Project’s Impact Areas

We focus on three interconnected areas critical to advancing equity:

• Innovation in Teaching and Learning: Create education models that center Black students through culturally affirming approaches that challenge traditional structures and transform how learning happens, ultimately serving all students. 
• Diversity in Education: Build pathways that increase and sustain Black educators and education leaders who transform where and how students learn.
• Pathways to Economic Mobility: Build pathways to wealth, ownership, and economic power for Black students, families, and communities through innovative educational programming.

Our Selection Criteria

We seek out extraordinary applicants who embody our values and vision across three categories:

Leader: We look for leaders whose influence and vision contribute to the collective well-being and advancement of the Black community. These leaders:

• Are Visionary: They demonstrate a strategic and pragmatic mindset, articulating a transformative vision for significant, positive change.
• Show Demonstrated Commitment: They embody steadfast dedication to your cause, inspiring and influencing others, and galvanizing community involvement.
• Are Adaptive: They assertively tackle challenges, turning setbacks into opportunities for innovation, while maintaining humility and thoughtfulness in problem-solving.

Organization: We look for organizations that drive significant change, anchored by a deep love for people and driven by the genius within communities of color. These organizations: 

• Have a Defined Problem: They clearly identify the issue they are addressing and explain in detail how your organization tackles root causes. 
• Take a Strategic Approach: They have clear, measurable, and achievable organizational goals with a well-defined strategy informed by thorough analysis. 
• Show Demonstrated Impact: They have a tested model that has produced positive results, incorporating continuous learning and iteration. 
• Have a Transformation Plan: They present a clear plan for using the $1M award to advance your organization's mission, vision, and long-term goals. 
• Embrace Collaboration: They use collaborate to build partnerships based on trust, love, and common goals. 

Radical Imagination: We seek leaders who challenge and redesign societal norms to build a just and equitable future. They demonstrate:

• Community-Rooted Leadership: They maintain and cultivate genuine community ties, integrating professional expertise and personal commitment to drive visionary, impactful strategies. 
• Long-Term Commitment: They are in it for the long haul, committing to sustained impact across generations and prioritizing long-lasting solutions over short-term gains. 
• Collectivism: They embody the philosophy of "I am because we are," actively engaging in collaborative networks and fostering community-reflective solutions. 

The Undiagnosed Diseases Network (UDN) Clinical and Data Coordinating Center aims to enhance diagnosis and research for individuals with undiagnosed diseases. This initiative focuses on engagement, education, and innovative diagnostic approaches. The center will oversee recruitment, participant support, and data management while fostering collaboration among various stakeholders. NINDS seeks proposals demonstrating the necessary infrastructure and partnerships to ensure effective implementation of the UDN's mission and transfer successful diagnostic methods into mainstream healthcare.

Who We Are

Buiding a stronger, More Vibrant Community

For over 70 years, the Scranton Area Community Foundation has served Northeastern Pennsylvania as a steward of charitable resources, a grantmaker, and a catalyst for positive change. Guided by our core values of collaboration, trust, integrity, innovation, and inclusivity, we work to ensure that our communities thrive with opportunities for all.

This scholarship is awarded to a graduating senior who has demonstrated the qualities of honesty, care, trustworthiness, and personal integrity, and who is active in sports and shows an interest in working with children or the elderly.

The Pulmonary Hypertension Fund, supported by the Patient Advocate Foundation, offers financial assistance for patients dealing with pulmonary hypertension. This fund covers essential healthcare costs, including medication copays and health insurance premiums. Patients must meet specific eligibility criteria, such as having a confirmed diagnosis and appropriate health insurance. Since 1996, the foundation has empowered millions to navigate healthcare challenges, ensuring they receive the care they need without financial burden.

Community Foundation of the Fox River Valley

The Community Foundation of the Fox River Valley is a collection of individual funds and resources given by local citizens to enhance and support the quality of life in the Fox River Valley of Illinois.

We are a tax-exempt public charity that allows individuals, businesses, and non-profit organizations to establish permanent endowments and temporary funds within the confines of one large foundation.

Foundation funds are used to provide grants to non-profit organizations and scholarships to area students. The Foundation also hosts a Youth Engagement in Philanthropy (YEP) program, which helps high school students learn more about philanthropy and empowers them to make a difference in the community.

The Community Foundation of the Fox River Valley serves the City of Aurora, Kane County, and Kendall County within the State of Illinois.

Olsson Roofing Company, Inc. Scholarship Fund

In 1988, Olsson Roofing Company, Inc. of Aurora created a scholarship fund within the Community Foundation for area students.

Scholarships from this fund are awarded in recognition of high scholastic achievement, participation in school activities and leadership potential.

These awards are reserved for students whose parents are actively involved in the roofing trade or construction industry.

Through the generosity and commitment of this civic-minded company, many students have received needed assistance for their college educations.

Community Foundation of the Fox River Valley

The Community Foundation of the Fox River Valley is a collection of individual funds and resources given by local citizens to enhance and support the quality of life in the Fox River Valley of Illinois.

We are a tax-exempt public charity that allows individuals, businesses, and non-profit organizations to establish permanent endowments and temporary funds within the confines of one large foundation.

Foundation funds are used to provide grants to non-profit organizations and scholarships to area students. The Foundation also hosts a Youth Engagement in Philanthropy (YEP) program, which helps high school students learn more about philanthropy and empowers them to make a difference in the community.

The Community Foundation of the Fox River Valley serves the City of Aurora, Kane County, and Kendall County within the State of Illinois.

Jerry J. Murphy MSW Scholarship Fund

The Jerry J. Murphy MSW Scholarship Fund provides scholarships to students pursuing a Master of Social Work degree.

Jerry Murphy is the retired Executive Director of the INC Board. He served residents of Kane County for over 28 years during his time with the organization.

INC Board, NFP, is an Illinois, not-for-profit corporation which was chartered as Mental Health and Mental Retardation Services on April 21, 1969, to promote the creation of local mental health boards authorized under 405 Illinois Compiled Statutes §20/3a.